Penicillins With Extended Spectrum

DrugDrug NameDrug Indication
DB00415AmpicillinFor treatment of infection (Respiratory, GI, UTI and meningitis) due to E. coli, P. mirabilis, enterococci, Shigella, S. typhosa and other Salmonella, nonpenicillinase-producing N. gononhoeae, H. influenzae, staphylococci, streptococci including streptoc
DB00578CarbenicillinFor the treatment of acute and chronic infections of the upper and lower urinary tract and in asymptomatic bacteriuria due to susceptible strains of bacteria.
DB00739HetacillinHetacillin is a beta-lactam antibiotic prodrug used to treat bacterial infections. In the body it gets converted to ampicillin.
DB00948MezlocillinUsed to treat serious gram–negative infections of the lungs, urinary tract, and skin.
DB01061AzlocillinFor the treatment of infections caused by Pseudomonas aeruginosa, Escherichia coli, and Haemophilus influenzae.
DB01163AmdinocillinUsed in the treatment of urinary tract infections caused by some strains of E. coli and klebsiella and enterobacter species. Used mainly against Gram negative organisms.
DB01602BacampicillinFor infections at the following sites: upper and lower respiratory tract; skin and soft tissue; urinary tract and acute uncomplicated gonococcal urethritis, when due to sensitive strains of the following organisms: Gram-positive: streptococci (including S. faecalis and S. pneumoniae) and nonpenicillinase-producing staphylococci; Gram-negative: H. influenzae, N. gonorrhoeae, E. coli, P. mirabilis, Salmonellae and Shigellae.
DB01604Pivampicillinor the treatment of respiratory tract infections (including acute bronchitis, acute exacerbations of chronic bronchitis and pneumonia); ear, nose and throat infections; gynecological infections; urinary tract infections (including acute uncomplicated gonococcal urethritis) when caused by non penicillinase-producing susceptible strains of the following organisms: gram-positive organisms, e.g., streptococci, pneumococci and staphylococci; gram-negative organisms, e.g., H. influenzae, N. gonorrhoeae, E. coli, P. mirabilis.
DB01605PivmecillinamUsed to treat infections due to mecillinam-sensitive organisms such as urinary tract infections, salmonellosis and typhoid fever.
DB01607TicarcillinFor the treatment of bacterial infections.
DB09319CarindacillinFor the treatment of acute and chronic infections of the upper and lower urinary tract and in asymptomatic bacteriuria (due to susceptible strains Escherichia coli, Proteus mirabilis, Morganella morganii, Providencia rettgeri, Proteus vulgaris, Pseudomonas, Enterobacter, and Enterococci.). Also indicated in the treatment of prostatitis (due to susceptible strains Escherichia coli Enterococcus (S. faecalis), Proteus mirabilis Enterobacter sp.).
DB12343TemocillinNot Available
DB13300EpicillinNot Available
DB13693SulbenicillinNot Available
DB13814TalampicillinNot Available
DB13816AspoxicillinNot Available
DB13836MetampicillinNot Available
DB00319PiperacillinFor the treatment of polymicrobial infections.
DB01060AmoxicillinFor the treatment of infections of the ear, nose, and throat, the genitourinary tract, the skin and skin structure, and the lower respiratory tract due to susceptible (only b-lactamase-negative) strains of Streptococcus spp. (a- and b-hemolytic strains only), S. pneumoniae, Staphylococcus spp., H. influenzae, E. coli, P. mirabilis, or E. faecalis. Also for the treatment of acute, uncomplicated gonorrhea (ano-genital and urethral infections) due to N. gonorrhoeae (males and females).
DrugDrug NameTargetType
DB00415AmpicillinSerum albumincarrier
DB00415AmpicillinSolute carrier family 22 member 5transporter
DB00415AmpicillinSolute carrier family 15 member 1transporter
DB00415AmpicillinSolute carrier family 15 member 2transporter
DB00415AmpicillinPenicillin-binding protein 2atarget
DB00415AmpicillinPenicillin-binding protein 1btarget
DB00415AmpicillinPenicillin-binding protein 3target
DB00415AmpicillinPenicillin-binding protein 1Atarget
DB00415AmpicillinPenicillin-binding protein 2Btarget
DB00415AmpicillinMonocarboxylate transporter 1transporter
DB00415AmpicillinSolute carrier family 15 member 1target
DB00415AmpicillinSolute carrier family 15 member 2target
DB00415AmpicillinAngiopoietin-1 receptortarget
DB00578CarbenicillinSolute carrier family 22 member 6transporter
DB00578CarbenicillinPenicillin-binding proteintarget
DB00578CarbenicillinCytosolic phospholipase A2enzyme
DB00739HetacillinPenicillin-binding protein 2atarget
DB00739HetacillinPenicillin-binding protein 1btarget
DB00739HetacillinPenicillin-binding protein 3target
DB00739HetacillinPenicillin-binding protein 1Atarget
DB00739HetacillinPenicillin-binding protein 2Btarget
DB00948MezlocillinPenicillin-binding protein 1Atarget
DB00948MezlocillinPenicillin-binding protein 2target
DB00948MezlocillinPenicillin-binding protein 3target
DB01061AzlocillinPenicillin-binding protein 1Atarget
DB01163AmdinocillinPenicillin-binding protein 2target
DB01163AmdinocillinPenicillin-binding protein 2atarget
DB01163AmdinocillinPenicillin-binding protein 3target
DB01163AmdinocillinPenicillin-binding protein 1Atarget
DB01163AmdinocillinPenicillin-binding protein 2Btarget
DB01163AmdinocillinPenicillin-binding protein 1btarget
DB01602BacampicillinPenicillin-binding protein 1Atarget
DB01604PivampicillinPenicillin-binding protein 1Atarget
DB01605PivmecillinamPenicillin-binding protein 1Atarget
DB01607TicarcillinPenicillin binding protein 2atarget
DB09319CarindacillinPenicillin-binding proteintarget
DB00319PiperacillinSolute carrier family 22 member 6transporter
DB00319PiperacillinPenicillin-binding protein 3target
DB00319PiperacillinPenicillin-binding protein 2Btarget
DB00319PiperacillinPenicillin-binding protein 2atarget
DB00319PiperacillinPenicillin-binding protein 1btarget
DB00319PiperacillinSolute carrier family 22 member 8transporter
DB01060AmoxicillinPenicillin-binding protein 1Atarget
DB01060AmoxicillinSolute carrier family 15 member 1transporter
DB01060AmoxicillinSolute carrier family 15 member 2transporter
DB01060AmoxicillinSolute carrier family 22 member 6transporter