Antimalarial methanolquinolines

Accession Number

DBCAT002335

Description

Not Available

ATC Classification

Drugs

Drug	Drug Description
Quinine	An alkaloid used to treat uncomplicated Plasmodium falciparum malaria.
Mefloquine	An antimalarial agent used in the prophylaxis and treatment of malaria caused by Plasmodium falciparum and Plasmodium vivax.

Drugs & Drug Targets

Drug	Target	Type
Quinine	Platelet glycoprotein IX	target
Quinine	Intermediate conductance calcium-activated potassium channel protein 4	target
Quinine	Cytochrome P450 3A4	enzyme
Quinine	Cytochrome P450 3A5	enzyme
Quinine	Cytochrome P450 1A1	enzyme
Quinine	Cytochrome P450 2D6	enzyme
Quinine	Cytochrome P450 1A2	enzyme
Quinine	Cytochrome P450 2C8	enzyme
Quinine	Cytochrome P450 2C9	enzyme
Quinine	Cytochrome P450 2C19	enzyme
Quinine	Cytochrome P450 2E1	enzyme
Quinine	Cytochrome P450 3A7	enzyme
Quinine	Solute carrier family 22 member 2	transporter
Quinine	Solute carrier family 22 member 1	transporter
Quinine	Solute carrier family 22 member 5	transporter
Quinine	P-glycoprotein 1	transporter
Quinine	Solute carrier organic anion transporter family member 1A2	transporter
Quinine	Solute carrier family 22 member 4	transporter
Quinine	Fe(II)-protoporphyrin IX	target
Quinine	Solute carrier organic anion transporter family member 1B1	transporter
Mefloquine	Cholinesterase	enzyme
Mefloquine	Cytochrome P450 3A4	enzyme
Mefloquine	Adenosine receptor A2a	target
Mefloquine	Fe(II)-protoporphyrin IX	target
Mefloquine	P-glycoprotein 1	transporter
Mefloquine	Cytochrome P450 19A1	enzyme
Mefloquine	Acetylcholinesterase	enzyme
Mefloquine	80S ribosomal subunit	target