Trimethoprim and Derivatives
- Name
- Trimethoprim and Derivatives
- Accession Number
- DBCAT002375
- Description
Not Available
- ATC Classification
- Drugs
Drug Drug Description Iclaprim Investigated for use/treatment in bacterial infection, skin infections/disorders, obesity, liver disease, kidney disease, and pneumonia. Brodimoprim Not Annotated Trimethoprim An antifolate antibiotic often used in combination with sulfamethoxazole to treat a number of infections, including those of the urinary tract, respiratory tract, and gastrointestinal tract. - Drugs & Drug Targets
Drug Target Type Iclaprim Dihydrofolate reductase target Trimethoprim Dihydrofolate reductase target Trimethoprim Cytochrome P450 2C8 enzyme Trimethoprim Cytochrome P450 3A4 enzyme Trimethoprim P-glycoprotein 1 transporter Trimethoprim Cytochrome P450 2C9 enzyme Trimethoprim Cytochrome P450 1A2 enzyme Trimethoprim Multidrug and toxin extrusion protein 1 transporter Trimethoprim Multidrug and toxin extrusion protein 2 transporter