Androgens and Estrogens

Name
Androgens and Estrogens
Accession Number
DBCAT002429
Description
Not Available
ATC Classification
Drugs
DrugDrug Description
PrasteroneA steroid formulated as a vaginal insert indicated for the treatment of moderate to severe dyspareunia associated with menopausal vulvar and vaginal atrophy.
TestosteroneA hormone used to treat hypogonadism, breast carcinoma in women, or the vasomotor symptoms of menopause.
EstradiolAn estrogenic steroid used to treat vasomotor symptoms of vulvar and vaginal atrophy in menopause, hypoestrogenism, prevention of postmenopausal osteoporosis, treatment of breast cancer, and advanced androgen-dependent carcinoma of the prostate.
MethyltestosteroneA synthetic anabolic steroid used for the replacement therapy in conditions associated with testosterone deficiencies in males, such as hypogonadism, and treatment of advancing inoperable metastatic breast cancer in females.
Drugs & Drug Targets
DrugTargetType
PrasteroneCytochrome P450 3A7enzyme
PrasteronePeroxisome proliferator-activated receptor alphatarget
PrasteroneEstrogen receptor alphatarget
PrasteroneSigma non-opioid intracellular receptor 1target
PrasteroneEstrogen receptor betatarget
PrasteroneNuclear receptor subfamily 1 group I member 2target
PrasteroneNuclear receptor subfamily 1 group I member 3target
PrasteroneGABA(A) Receptortarget
PrasteroneNMDA receptortarget
PrasteroneAndrogen receptortarget
PrasteroneEstradiol 17-beta-dehydrogenase 1enzyme
PrasteroneBile salt sulfotransferaseenzyme
PrasteroneSulfotransferase family cytosolic 2B member 1enzyme
Prasterone3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1enzyme
PrasteroneCholesterol oxidaseenzyme
PrasteroneSteroid 17-alpha-hydroxylase/17,20 lyaseenzyme
PrasteroneSolute carrier organic anion transporter family member 1B3transporter
PrasteroneSolute carrier organic anion transporter family member 2B1transporter
PrasteroneSolute carrier organic anion transporter family member 1B1transporter
PrasteroneSolute carrier organic anion transporter family member 1A2transporter
PrasteroneMultidrug resistance-associated protein 1transporter
PrasteroneATP-binding cassette sub-family G member 2transporter
PrasteroneMultidrug resistance-associated protein 4transporter
TestosteroneAndrogen receptortarget
TestosteroneCytochrome P450 3A4enzyme
TestosteroneCytochrome P450 19A1enzyme
TestosteroneAmine oxidase [flavin-containing] Aenzyme
TestosteroneCholesterol side-chain cleavage enzyme, mitochondrialenzyme
TestosteroneSerum albumincarrier
TestosteroneSex hormone-binding globulincarrier
TestosteroneCytochrome P450 3A5enzyme
TestosteroneCytochrome P450 3A7enzyme
TestosteroneSolute carrier family 22 member 8transporter
TestosteroneSolute carrier family 22 member 7transporter
TestosteroneSodium/bile acid cotransportertransporter
TestosteroneATP-binding cassette sub-family G member 2transporter
TestosteroneCytochrome P450 1A1enzyme
TestosteroneCytochrome P450 1B1enzyme
TestosteroneCytochrome P450 2A13enzyme
TestosteroneCytochrome P450 2B6enzyme
TestosteroneCytochrome P450 2C19enzyme
TestosteroneCytochrome P450 2C8enzyme
TestosteroneCytochrome P450 2C9enzyme
TestosteroneCytochrome P450 3A43enzyme
TestosteroneEstrogen receptor alphatarget
TestosteroneMineralocorticoid receptortarget
TestosteroneSolute carrier organic anion transporter family member 1B3transporter
EstradiolEstrogen receptor alphatarget
EstradiolNuclear receptor subfamily 1 group I member 2target
EstradiolSex hormone-binding globulincarrier
EstradiolEstrogen receptor betatarget
EstradiolCytochrome P450 1A2enzyme
EstradiolUDP-glucuronosyltransferase 1-1enzyme
EstradiolSerum albumincarrier
EstradiolFatty acid-binding protein, intestinalcarrier
EstradiolCytochrome P450 3A4enzyme
EstradiolCytochrome P450 3A5enzyme
EstradiolCytochrome P450 3A7enzyme
EstradiolSolute carrier family 22 member 2transporter
EstradiolSolute carrier family 22 member 3transporter
EstradiolMultidrug resistance-associated protein 7transporter
EstradiolSolute carrier family 22 member 11transporter
EstradiolATP-binding cassette sub-family G member 2transporter
EstradiolSolute carrier organic anion transporter family member 1B1transporter
EstradiolP-glycoprotein 1transporter
EstradiolCytochrome P450 1A1enzyme
EstradiolCytochrome P450 1B1enzyme
EstradiolCytochrome P450 2C19enzyme
EstradiolCytochrome P450 2C8enzyme
EstradiolCytochrome P450 2C9enzyme
EstradiolSolute carrier family 22 member 8transporter
EstradiolSolute carrier organic anion transporter family member 1B3transporter
EstradiolSolute carrier organic anion transporter family member 1C1transporter
EstradiolNeuronal acetylcholine receptor subunit alpha-4target
EstradiolG-protein coupled estrogen receptor 1target
EstradiolATP synthase subunit atarget
EstradiolBeclin-1target
EstradiolUDP-glucuronosyltransferase 2B15enzyme
EstradiolCatechol O-methyltransferaseenzyme
EstradiolUDP-glucuronosyltransferases (UGTs)enzyme
MethyltestosteroneCytochrome P450 2B6enzyme
MethyltestosteroneCytochrome P450 3A4enzyme
MethyltestosteroneAndrogen receptortarget
MethyltestosteroneSolute carrier organic anion transporter family member 1A2transporter
MethyltestosteroneSolute carrier family 22 member 8transporter
MethyltestosteroneSerum albumincarrier
MethyltestosteroneSex hormone-binding globulincarrier
MethyltestosteroneEstrogen receptor alphatarget
MethyltestosteroneCytochrome P450 19A1enzyme