Peripheral Vasodilators

Name
Peripheral Vasodilators
Accession Number
DBCAT002432
Description
Not Available
ATC Classification
Drugs
DrugDrug Description
FasudilFasudil has been investigated in Carotid Stenosis.
Ergoloid mesylateA nootropic with an unknown mechanism of action indicated in individuals over sixty who manifest signs and symptoms of an idiopathic decline in mental capacity.
NiacinA B vitamin used to treat hypertriglyceridemia and pellagra.
PhentolamineAn alpha adrenergic antagonist used to reverse soft tissue anesthesia.
NicergolineFor the treatment of senile dementia, migraines of vascular origin, transient ischemia, platelet hyper-aggregability, and macular degeneration.
TolazolineA vasodilator used to treat pulmonary artery anomalies.
PentoxifyllineA methylxanthine derivative used to treat intermittent claudication caused by chronic occlusive arterial disease of the limbs.
PhenoxybenzamineAn alpha adrenergic agonist used to treat pheochromocytoma and episodes of hypertension and sweating.
CyclandelateA vasodilator used for the treatment of various blood vessel diseases, such as claudication and arteriosclerosis.
NylidrinA vasodilator used to treat patients with peripheral vascular disorders, and elderly patients with symptoms associated with organic mental disorders.
IsoxsuprineA beta-adrenergic agonist used in the symptomatic treatment of cerebrovascular insufficiency, peripheral vascular disease of arteriosclerosis obliterans, thromboangiitis obliterans (Buerger's disease) and Raynaud's disease.
Inositol nicotinateA vasodilator and source of niacin found in dietary supplements.
IfenprodilIfenprodil is a selective NMDA receptor (glutamate) antagonist.
XanthinolA vasodilatory niacin found in diet supplements.
CinepazideCinepazide has been used in trials studying the treatment of Ischemic Stroke.
KallidinogenaseNot Annotated
BamethanNot Annotated
SuloctidilNot Annotated
DihydroergocristineAn ergot alkaloid used to delay progressive mental decline in conditions like Alzheimer's.
VisnadineNot Annotated
VincamineVincamine is a monoterpenoid indole alkaloid obtained from the leaves of Vinca minor with a vasodilatory property. Studies indicate that vincamine increases the regional cerebral blood flow.
BencyclaneA vasodilator agent found to be effective in a variety of peripheral circulation disorders. It has various other potentially useful pharmacological effects. Its mechanism may involve block of calcium channels.
BuflomedilNot Annotated
NaftidrofurylNot Annotated
PentifyllineNot Annotated
ButalamineNot Annotated
CiclonicateNot Annotated
AzapetineNot Annotated
CetiedilNot Annotated
VinburnineNot Annotated
Etofylline nicotinateEtofylline nicotinate, a theophylline derivative, is a drug that causes vasodilation and relaxation of smooth muscle.
MoxisylyteBy the WHO, moxisylyte is indicated for the symptomatic management of sequelae of cerebral infarction or hemorrhage. The cerebral infarction is characterized by the blockage of the artery either by...
Nicotinyl alcoholA direct-acting peripheral vasodilator that causes flushing and may decrease blood pressure. It is used in vasospasm and threatened gangrene. [PubChem]
Drugs & Drug Targets
DrugTargetType
FasudilcAMP-dependent protein kinase inhibitor alphatarget
FasudilcAMP-dependent protein kinase catalytic subunit alphatarget
FasudilRho-associated protein kinase 1target
FasudilRho-associated protein kinase 2target
Ergoloid mesylateDopamine receptortarget
Ergoloid mesylateAlpha adrenergic receptortarget
Ergoloid mesylateBeta adrenergic receptortarget
Ergoloid mesylateSerotonin Receptorstarget
Ergoloid mesylateCytochrome P450 3A4enzyme
NiacinHydroxycarboxylic acid receptor 2target
NiacinNicotinamide N-methyltransferasetarget
NiacinNicotinate-nucleotide pyrophosphorylase [carboxylating]target
NiacinHydroxycarboxylic acid receptor 3target
NiacinSolute carrier family 22 member 5transporter
NiacinSolute carrier organic anion transporter family member 2B1transporter
NiacinMonocarboxylate transporter 1transporter
NiacinCytochrome P450 2D6enzyme
NiacinSodium-coupled monocarboxylate transporter 1transporter
NiacinMonocarboxylate transporter 4transporter
NiacinThyroxine-binding globulincarrier
NiacinCytochrome P450 3A4enzyme
NiacinCytochrome P450 2E1enzyme
PhentolamineAlpha-2A adrenergic receptortarget
PhentolamineAlpha-1A adrenergic receptortarget
PhentolamineAlpha-1B adrenergic receptortarget
PhentolamineAlpha-1D adrenergic receptortarget
NicergolineAlpha-1A adrenergic receptortarget
NicergolineCytochrome P450 2D6enzyme
TolazolineAlpha-1A adrenergic receptortarget
TolazolineAlpha-2A adrenergic receptortarget
TolazolineHistamine H1 receptortarget
TolazolineHistamine H2 receptortarget
TolazolineAlpha-2C adrenergic receptortarget
TolazolineAlpha-2B adrenergic receptortarget
PentoxifyllinecAMP-specific 3',5'-cyclic phosphodiesterase 4Btarget
PentoxifyllinecAMP-specific 3',5'-cyclic phosphodiesterase 4Atarget
Pentoxifylline5'-nucleotidasetarget
PentoxifyllinecGMP-specific 3',5'-cyclic phosphodiesterasetarget
PentoxifyllineAdenosine receptor A1target
PentoxifyllineAdenosine receptor A2atarget
PentoxifyllineCytochrome P450 1A2enzyme
PhenoxybenzamineAlpha-1A adrenergic receptortarget
PhenoxybenzamineCalmodulintarget
PhenoxybenzamineSolute carrier family 22 member 2transporter
PhenoxybenzamineSolute carrier family 22 member 1transporter
PhenoxybenzamineSolute carrier family 22 member 3transporter
PhenoxybenzamineAlpha-2A adrenergic receptortarget
PhenoxybenzamineAlpha-2C adrenergic receptortarget
PhenoxybenzamineAlpha-2B adrenergic receptortarget
PhenoxybenzamineBeta-2 adrenergic receptortarget
PhenoxybenzamineAlpha-1B adrenergic receptortarget
PhenoxybenzamineAlpha-1D adrenergic receptortarget
CyclandelateVoltage-dependent calcium channel subunit alpha-2/delta-1target
CyclandelateLiver carboxylesterase 1target
CyclandelateCytochrome P450 3A4enzyme
NylidrinCatechol O-methyltransferaseenzyme
NylidrinVoltage-dependent T-type calcium channel subunit alpha-1Itarget
NylidrinInterferon alpha/beta receptor 2target
NylidrinCytochrome P450 3A4enzyme
Inositol nicotinateSodium-coupled monocarboxylate transporter 1transporter
Inositol nicotinateATP synthase subunit beta, mitochondrialenzyme
Inositol nicotinateHydroxycarboxylic acid receptor 3target
Inositol nicotinateHydroxycarboxylic acid receptor 2target
Inositol nicotinateDiacylglycerol O-acyltransferase 2enzyme
IfenprodilGlutamate receptor ionotropic, NMDA 1target
IfenprodilGlutamate receptor ionotropic, NMDA 2Btarget
Xanthinol60S ribosomal protein L3target
XanthinolNAD(P) transhydrogenase, mitochondrialtarget
XanthinolGlyceraldehyde-3-phosphate dehydrogenasetarget
XanthinolIsocitrate dehydrogenase [NAD] subunit alpha, mitochondrialtarget
Xanthinol2-oxoglutarate dehydrogenase, mitochondrialtarget
XanthinolMalate dehydrogenase, mitochondrialtarget
DihydroergocristineSerotonin Receptorstarget
DihydroergocristineBeta adrenergic receptortarget
DihydroergocristineAlpha adrenergic receptortarget
DihydroergocristineDopamine receptortarget
DihydroergocristineBile salt export pumptransporter
DihydroergocristineCytochrome P450 3A4enzyme
BencyclaneCytochrome P450 3A4enzyme
PentifyllineCytochrome P450 1A2enzyme
MoxisylyteCholinesteraseenzyme
MoxisylyteCytochrome P450 3A Subfamilyenzyme
MoxisylyteAlpha adrenergic receptortarget