Nitroimidazole Derivatives

Name
Nitroimidazole Derivatives
Accession Number
DBCAT002484
Description
Not Available
ATC Classification
Drugs
DrugDrug Description
BenznidazoleA trypanocidal agent used to treat Chagas disease.
NimorazoleNimorazole has been used in trials studying the treatment of Hypoxia, Radiotherapy, Hypoxic Modification, Gene Profile, Gene Signature, and Head and Neck Squamous Cell Carcinoma, among others.
PropenidazoleNot Annotated
TinidazoleA nitroimidazole used to treat trichomoniasis, giardiasis, amebiasis, and bacterial vaginosis.
MetronidazoleA nitroimidazole used to treat trichomoniasis, amebiasis, inflammatory lesions of rosacea, and bacterial infections, as well as prevent postoperative infections.
SecnidazoleA nitroimidazole antibiotic used to treat bacterial vaginosis.
OrnidazoleOrnidazole has been used in trials studying the prevention of Elective Colorectal Surgery.
AzanidazoleNot Annotated
FexinidazoleFexinidazole has been investigated for the treatment of Disease, Chagas and South American Trypanosomiasis.
Drugs & Drug Targets
DrugTargetType
TinidazoleCytochrome P450 3A4enzyme
TinidazoleDNAtarget
TinidazoleBile salt export pumptransporter
MetronidazoleOxygen-insensitive NADPH nitroreductasetarget
MetronidazoleCytochrome P450 2C9enzyme
MetronidazoleCytochrome P450 3A4enzyme
MetronidazoleCytochrome P450 2C8enzyme
MetronidazoleUDP-glucuronosyltransferase 1-1enzyme
MetronidazoleAnaerobic bacterial DNAtarget
MetronidazoleProtozoal DNAtarget
MetronidazoleP-glycoprotein 1transporter
MetronidazoleCytochrome P450 2A6enzyme
MetronidazoleCytochrome P450 3A5enzyme
MetronidazoleCytochrome P450 3A7enzyme