Cytochrome P-450 CYP2A6 Inducers

Name
Cytochrome P-450 CYP2A6 Inducers
Accession Number
DBCAT002617
Description
Not Available
Drugs
DrugDrug Description
PentobarbitalA barbiturate drug used to induce sleep, cause sedation, and control certain types of seizures.
RifampicinAn antibiotic used to treat several types of mycobacterial infections including Mycobacterium avium complex, leprosy, and in combination with other antibacterials to treat latent or active tuberculosis.
Valproic acidAn anticonvulsant used to control complex partial seizures and both simple and complex absence seizures.
DexamethasoneA glucocorticoid available in various modes of administration that is used for the treatment of various inflammatory conditions, including bronchial asthma, as well as endocrine and rheumatic disorders.
EletriptanA triptan used for the treatment of migraines.
PhenobarbitalA long-lasting barbiturate and anticonvulsant used in the treatment of all types of seizures, except for absent seizures.
ProgesteroneA hormone used for a variety of functions, including contraception, control of abnormal uterine bleeding, maintenance of pregnancy, and prevention of endometrial hyperplasia.
PrednisoneA corticosteroid used to treat inflammation or immune-mediated reactions and to treat endocrine or neoplastic diseases.
HydrocortisoneA glucocorticoid used to treat corticosteroid-responsive dermatoses, endocrine disorders, immune conditions, and allergic disorders.
BudesonideA corticosteroid used to treat Crohn's disease, asthma, COPD, hay fever and allergies, and ulcerative colitis.
MethylprednisoloneA corticosteroid used to treat inflammation or immune reactions across a variety of organ systems, endocrine conditions, and neoplastic diseases.
BetamethasoneA systemic corticosteroid used to relieve inflammation in various conditions, including but not limited to allergic states, dermatologic disorders, gastrointestinal diseases, and hematological disorders.
Prednisolone phosphateA corticosteroid used to treat inflammation, immune reactions, as well as endocrine or neoplastic conditions.
Dexamethasone acetateCommonly known as decadron, dexamethasone acetate is a glucocorticosteroid previously marketed in the USA for the treatment of inflammatory respiratory, allergic, autoimmune, and other conditions.[T797,L10695,L14348] Developed in 1957, dexamethasone is...
Drugs & Drug Targets
DrugTargetType
PentobarbitalGamma-aminobutyric acid receptor subunit alpha-1target
PentobarbitalCytochrome P450 3A4enzyme
PentobarbitalGamma-aminobutyric acid receptor subunit alpha-4target
PentobarbitalGamma-aminobutyric acid receptor subunit alpha-6target
PentobarbitalGamma-aminobutyric acid receptor subunit alpha-2target
PentobarbitalGamma-aminobutyric acid receptor subunit alpha-3target
PentobarbitalGamma-aminobutyric acid receptor subunit alpha-5target
PentobarbitalNeuronal acetylcholine receptor subunit alpha-4target
PentobarbitalNeuronal acetylcholine receptor subunit alpha-7target
PentobarbitalGlutamate receptor 2target
PentobarbitalGlutamate receptor ionotropic, kainate 2target
PentobarbitalCytochrome P450 2C19enzyme
PentobarbitalCytochrome P450 2A6enzyme
PentobarbitalGABA(A) Receptortarget
PentobarbitalNMDA receptortarget
PentobarbitalNuclear receptor subfamily 1 group I member 2target
RifampicinDNA-directed RNA polymerase subunit betatarget
RifampicinNuclear receptor subfamily 1 group I member 2target
RifampicinCytochrome P450 3A4enzyme
RifampicinCytochrome P450 1A2enzyme
RifampicinCytochrome P450 2C8enzyme
RifampicinUDP-glucuronosyltransferase 1-1enzyme
RifampicinCytochrome P450 2C9enzyme
RifampicinCytochrome P450 2B6enzyme
RifampicinCytochrome P450 2C19enzyme
RifampicinCanalicular multispecific organic anion transporter 2transporter
RifampicinMultidrug resistance-associated protein 5transporter
RifampicinP-glycoprotein 1transporter
RifampicinCanalicular multispecific organic anion transporter 1transporter
RifampicinSolute carrier organic anion transporter family member 2B1transporter
RifampicinBile salt export pumptransporter
RifampicinMultidrug resistance-associated protein 1transporter
RifampicinSolute carrier organic anion transporter family member 1A2transporter
RifampicinSolute carrier organic anion transporter family member 1B3transporter
RifampicinSolute carrier family 22 member 7transporter
RifampicinSolute carrier organic anion transporter family member 1B1transporter
RifampicinCytochrome P450 2A6enzyme
RifampicinCytochrome P450 2E1enzyme
RifampicinCytochrome P450 3A43enzyme
RifampicinCytochrome P450 3A7enzyme
RifampicinSolute carrier family 22 member 6transporter
RifampicinSolute carrier family 22 member 8transporter
RifampicinUDP-glucuronosyltransferase 1-9enzyme
RifampicinCytochrome P450 3A5enzyme
RifampicinSerum albumincarrier
Rifampicinalpha1-acid glycoproteincarrier
Valproic acidHistone deacetylase 9target
Valproic acidShort/branched chain specific acyl-CoA dehydrogenase, mitochondrialtarget
Valproic acidCytochrome P450 2A6enzyme
Valproic acidCytochrome P450 2B6enzyme
Valproic acidCytochrome P450 2C9enzyme
Valproic acidSolute carrier family 22 member 5transporter
Valproic acidSolute carrier family 22 member 6transporter
Valproic acidSolute carrier family 22 member 8transporter
Valproic acidMonocarboxylate transporter 1transporter
Valproic acidSolute carrier family 22 member 7transporter
Valproic acidCytochrome P450 3A5enzyme
Valproic acidUDP-glucuronosyltransferase 1-9enzyme
Valproic acidProstaglandin G/H synthase 1enzyme
Valproic acidCytochrome P450 1A2enzyme
Valproic acidCytochrome P450 2C19enzyme
Valproic acidCytochrome P450 3A4enzyme
Valproic acidUDP-glucuronosyltransferase 1-4enzyme
Valproic acidUDP-glucuronosyltransferase 1-8enzyme
Valproic acidUDP-glucuronosyltransferase 1-10enzyme
Valproic acidUDP-glucuronosyltransferase 1-6enzyme
Valproic acidUDP-glucuronosyltransferase 1-3enzyme
Valproic acidUDP-glucuronosyltransferase 2B7enzyme
Valproic acidUDP-glucuronosyltransferase 2B15enzyme
Valproic acid2-oxoglutarate dehydrogenase, mitochondrialtarget
Valproic acidSuccinate-semialdehyde dehydrogenase, mitochondrialtarget
Valproic acidSodium channel proteintarget
Valproic acidHistone deacetylase 2target
Valproic acidPeroxisome proliferator-activated receptor alphatarget
Valproic acidPeroxisome proliferator-activated receptor deltatarget
Valproic acidPeroxisome proliferator-activated receptor gammatarget
Valproic acidSerum albumincarrier
Valproic acidUDP-glucuronosyltransferase 1-1enzyme
Valproic acidSolute carrier organic anion transporter family member 2B1transporter
DexamethasoneGlucocorticoid receptortarget
DexamethasoneAnnexin A1target
DexamethasoneNitric oxide synthase, inducibletarget
DexamethasoneNuclear receptor subfamily 0 group B member 1target
DexamethasoneCytochrome P450 3A4enzyme
DexamethasoneCytochrome P450 3A5enzyme
DexamethasoneCytochrome P450 3A7enzyme
DexamethasoneBile salt export pumptransporter
DexamethasoneP-glycoprotein 1transporter
DexamethasoneCanalicular multispecific organic anion transporter 1transporter
DexamethasoneSolute carrier organic anion transporter family member 1A2transporter
DexamethasoneATP-binding cassette sub-family G member 2transporter
DexamethasoneSteroid 17-alpha-hydroxylase/17,20 lyaseenzyme
DexamethasoneCytochrome P450 1A1enzyme
DexamethasoneCytochrome P450 2A6enzyme
DexamethasoneCytochrome P450 2B6enzyme
DexamethasoneCytochrome P450 2C19enzyme
DexamethasoneCytochrome P450 2C8enzyme
DexamethasoneCytochrome P450 2E1enzyme
DexamethasoneCytochrome P450 3A43enzyme
DexamethasoneCytochrome P450 4A11enzyme
DexamethasoneNuclear receptor subfamily 1 group I member 2target
DexamethasoneCytochrome P450 11B1, mitochondrialenzyme
DexamethasoneSerum albumincarrier
DexamethasoneCorticosteroid 11-beta-dehydrogenase isozyme 2enzyme
DexamethasoneCorticosteroid 11-beta-dehydrogenase isozyme 1enzyme
DexamethasoneSolute carrier family 22 member 8transporter
Eletriptan5-hydroxytryptamine receptor 1Dtarget
Eletriptan5-hydroxytryptamine receptor 1Atarget
Eletriptan5-hydroxytryptamine receptor 1Ftarget
Eletriptan5-hydroxytryptamine receptor 1Btarget
EletriptanCytochrome P450 3A4enzyme
EletriptanCytochrome P450 2D6enzyme
EletriptanCytochrome P450 2C9enzyme
EletriptanCytochrome P450 2C19enzyme
EletriptanProstaglandin G/H synthase 1enzyme
EletriptanCytochrome P450 2A6enzyme
EletriptanP-glycoprotein 1transporter
PhenobarbitalGamma-aminobutyric acid receptor subunit alpha-1target
PhenobarbitalCytochrome P450 2C19enzyme
PhenobarbitalCytochrome P450 2C9enzyme
PhenobarbitalCytochrome P450 2B6enzyme
PhenobarbitalCytochrome P450 2C8enzyme
PhenobarbitalCytochrome P450 1A2enzyme
PhenobarbitalCytochrome P450 3A4enzyme
PhenobarbitalCanalicular multispecific organic anion transporter 2transporter
PhenobarbitalBile salt export pumptransporter
PhenobarbitalP-glycoprotein 1transporter
PhenobarbitalMultidrug resistance-associated protein 1transporter
PhenobarbitalSolute carrier organic anion transporter family member 2A1transporter
PhenobarbitalCanalicular multispecific organic anion transporter 1transporter
PhenobarbitalNeuronal acetylcholine receptor subunit alpha-4target
PhenobarbitalNeuronal acetylcholine receptor subunit alpha-7target
PhenobarbitalGlutamate receptor 2target
PhenobarbitalGlutamate receptor ionotropic, kainate 2target
PhenobarbitalCytochrome P450 2A6enzyme
PhenobarbitalCytochrome P450 2E1enzyme
PhenobarbitalCytochrome P450 3A5enzyme
PhenobarbitalCytochrome P450 1A1enzyme
PhenobarbitalCytochrome P450 2C18enzyme
PhenobarbitalCytochrome P450 3A7enzyme
PhenobarbitalCytochrome P450 4B1enzyme
PhenobarbitalNMDA receptortarget
PhenobarbitalNuclear receptor subfamily 1 group I member 2target
PhenobarbitalUDP-glucuronosyltransferase 1-1enzyme
PhenobarbitalUDP-glucuronosyltransferase 2B7enzyme
ProgesteroneProgesterone receptortarget
ProgesteroneEstrogen receptor alphatarget
ProgesteroneSteroid 17-alpha-hydroxylase/17,20 lyasetarget
ProgesteroneCytochrome P450 2C19enzyme
ProgesteroneCytochrome P450 2C9enzyme
ProgesteroneCytochrome P450 3A4enzyme
ProgesteroneCytochrome P450 3A5enzyme
ProgesteroneCytochrome P450 3A7enzyme
ProgesteroneP-glycoprotein 1transporter
ProgesteroneSolute carrier family 22 member 2transporter
ProgesteroneSolute carrier family 22 member 1transporter
ProgesteroneSolute carrier family 22 member 3transporter
ProgesteroneBile salt export pumptransporter
ProgesteroneMultidrug resistance-associated protein 1transporter
ProgesteroneSodium/bile acid cotransportertransporter
ProgesteroneSteroid 17-alpha-hydroxylase/17,20 lyaseenzyme
ProgesteroneCytochrome P450 1A1enzyme
ProgesteroneCytochrome P450 1B1enzyme
ProgesteroneCytochrome P450 2A6enzyme
ProgesteroneCytochrome P450 2D6enzyme
ProgesteroneMineralocorticoid receptortarget
ProgesteroneKappa-type opioid receptortarget
ProgesteroneAlpha-1-acid glycoprotein 1target
ProgesteroneGlucocorticoid receptortarget
ProgesteroneAndrogen receptortarget
ProgesteroneSex hormone-binding globulintarget
ProgesteroneSolute carrier organic anion transporter family member 1B1transporter
ProgesteroneATP-binding cassette sub-family G member 2transporter
ProgesteroneEstrogen receptor betatarget
ProgesteroneSolute carrier organic anion transporter family member 1B3transporter
PrednisoneGlucocorticoid receptortarget
PrednisoneCytochrome P450 3A4enzyme
PrednisoneP-glycoprotein 1transporter
PrednisoneSolute carrier organic anion transporter family member 1A2transporter
PrednisoneCytochrome P450 2C19enzyme
PrednisoneSerum albumincarrier
PrednisoneCytochrome P450 3A5enzyme
PrednisoneCorticosteroid-binding globulincarrier
PrednisoneCytochrome P450 3A Subfamilyenzyme
PrednisoneCytochrome P450 2A6enzyme
PrednisoneCytochrome P450 1B1enzyme
PrednisoneCytochrome P450 2B6enzyme
PrednisoneCytochrome P450 2C8enzyme
PrednisoneCytochrome P450 2C9enzyme
PrednisoneCorticosteroid 11-beta-dehydrogenase isozyme 1enzyme
HydrocortisoneAnnexin A1target
HydrocortisoneGlucocorticoid receptortarget
HydrocortisoneSex hormone-binding globulincarrier
HydrocortisoneCytochrome P450 3A4enzyme
HydrocortisoneCytochrome P450 3A5enzyme
HydrocortisoneCytochrome P450 3A7enzyme
HydrocortisoneP-glycoprotein 1transporter
HydrocortisoneSolute carrier organic anion transporter family member 1A2transporter
HydrocortisoneCytochrome P450 11B1, mitochondrialenzyme
HydrocortisoneCytochrome P450 11B2, mitochondrialenzyme
HydrocortisoneCytochrome P450 2C8enzyme
HydrocortisoneCorticosteroid-binding globulincarrier
HydrocortisoneSolute carrier family 22 member 8transporter
Hydrocortisone3-oxo-5-beta-steroid 4-dehydrogenaseenzyme
Hydrocortisone3-oxo-5-alpha-steroid 4-dehydrogenase 2enzyme
HydrocortisoneCorticosteroid 11-beta-dehydrogenase isozyme 2enzyme
HydrocortisoneCorticosteroid 11-beta-dehydrogenase isozyme 1enzyme
HydrocortisoneCytochrome P450 2A6enzyme
HydrocortisoneCytochrome P450 1B1enzyme
HydrocortisoneCytochrome P450 2B6enzyme
HydrocortisoneCytochrome P450 2C9enzyme
HydrocortisoneCytochrome P450 2C19enzyme
BudesonideGlucocorticoid receptortarget
BudesonideCytochrome P450 3A4enzyme
BudesonideCytochrome P450 3A5enzyme
BudesonideBile salt export pumptransporter
BudesonideP-glycoprotein 1transporter
BudesonideAnnexin A1target
BudesonideCytochrome P450 3A Subfamilyenzyme
BudesonideCytochrome P450 2A6enzyme
BudesonideCytochrome P450 1B1enzyme
BudesonideCytochrome P450 2B6enzyme
BudesonideCytochrome P450 2C8enzyme
BudesonideCytochrome P450 2C9enzyme
BudesonideCytochrome P450 2C19enzyme
BudesonideCorticosteroid-binding globulincarrier
BudesonideSolute carrier organic anion transporter family member 1A2transporter
BudesonideSolute carrier family 22 member 8transporter
BudesonideSerum albumincarrier
MethylprednisoloneGlucocorticoid receptortarget
MethylprednisoloneCytochrome P450 3A4enzyme
MethylprednisoloneP-glycoprotein 1transporter
MethylprednisoloneCytochrome P450 3A Subfamilyenzyme
MethylprednisoloneCytochrome P450 2A6enzyme
MethylprednisoloneCytochrome P450 1B1enzyme
MethylprednisoloneCytochrome P450 2B6enzyme
MethylprednisoloneCytochrome P450 2C8enzyme
MethylprednisoloneCytochrome P450 2C9enzyme
MethylprednisoloneCytochrome P450 2C19enzyme
MethylprednisoloneAnnexin A1target
Methylprednisolone20-ketosteroid reductase (20-hydroxysteroid dehydrogenase)enzyme
Methylprednisolone11beta-hydroxysteroid dehydrogenaseenzyme
MethylprednisoloneSerum albumincarrier
BetamethasoneGlucocorticoid receptortarget
BetamethasoneCytochrome P450 3A4enzyme
BetamethasoneP-glycoprotein 1transporter
BetamethasoneCytochrome P450 19A1enzyme
BetamethasoneCytochrome P450 3A5enzyme
BetamethasoneCytochrome P450 3A7enzyme
BetamethasoneCytochrome P450 2A6enzyme
BetamethasoneCytochrome P450 1B1enzyme
BetamethasoneCytochrome P450 2B6enzyme
BetamethasoneCytochrome P450 2C8enzyme
BetamethasoneCytochrome P450 2C9enzyme
BetamethasoneCytochrome P450 2C19enzyme
BetamethasoneSerum albumincarrier
BetamethasoneCorticosteroid-binding globulincarrier
Prednisolone phosphateCytochrome P450 3A4enzyme
Prednisolone phosphateCytochrome P450 3A5enzyme
Prednisolone phosphateCytochrome P450 3A Subfamilyenzyme
Prednisolone phosphateCytochrome P450 2A6enzyme
Prednisolone phosphateCytochrome P450 1B1enzyme
Prednisolone phosphateCytochrome P450 2B6enzyme
Prednisolone phosphateCytochrome P450 2C8enzyme
Prednisolone phosphateCytochrome P450 2C9enzyme
Prednisolone phosphateCytochrome P450 2C19enzyme
Prednisolone phosphateCorticosteroid 11-beta-dehydrogenase isozyme 2enzyme
Prednisolone phosphateCorticosteroid 11-beta-dehydrogenase isozyme 1enzyme
Prednisolone phosphateGlucocorticoid receptortarget
Prednisolone phosphateAnnexin A1target
Prednisolone phosphateSolute carrier organic anion transporter family member 1A2transporter
Prednisolone phosphateP-glycoprotein 1transporter
Prednisolone phosphateSolute carrier family 22 member 8transporter
Prednisolone phosphateCorticosteroid-binding globulincarrier
Prednisolone phosphateSerum albumincarrier
Dexamethasone acetateGlucocorticoid receptortarget
Dexamethasone acetateAnnexin A1target
Dexamethasone acetateNitric oxide synthase, inducibletarget
Dexamethasone acetateNuclear receptor subfamily 0 group B member 1target
Dexamethasone acetateCytochrome P450 3A4enzyme
Dexamethasone acetateCytochrome P450 3A5enzyme
Dexamethasone acetateCytochrome P450 3A7enzyme
Dexamethasone acetateBile salt export pumptransporter
Dexamethasone acetateP-glycoprotein 1transporter
Dexamethasone acetateCanalicular multispecific organic anion transporter 1transporter
Dexamethasone acetateSolute carrier organic anion transporter family member 1A2transporter
Dexamethasone acetateATP-binding cassette sub-family G member 2transporter
Dexamethasone acetateSteroid 17-alpha-hydroxylase/17,20 lyaseenzyme
Dexamethasone acetateCytochrome P450 1A1enzyme
Dexamethasone acetateCytochrome P450 2A6enzyme
Dexamethasone acetateCytochrome P450 2B6enzyme
Dexamethasone acetateCytochrome P450 2C19enzyme
Dexamethasone acetateCytochrome P450 2C8enzyme
Dexamethasone acetateCytochrome P450 2E1enzyme
Dexamethasone acetateCytochrome P450 3A43enzyme
Dexamethasone acetateCytochrome P450 4A11enzyme
Dexamethasone acetateNuclear receptor subfamily 1 group I member 2target
Dexamethasone acetateCytochrome P450 11B1, mitochondrialenzyme
Dexamethasone acetateSerum albumincarrier
Dexamethasone acetateCorticosteroid 11-beta-dehydrogenase isozyme 2enzyme
Dexamethasone acetateCorticosteroid 11-beta-dehydrogenase isozyme 1enzyme
Dexamethasone acetateSolute carrier family 22 member 8transporter