DrugDrug NameDrug Indication
DB01016GlyburideIndicated as an adjunct to diet to lower the blood glucose in patients with NIDDM whose hyperglycemia cannot be satisfactorily controlled by diet alone.
DB01586Ursodeoxycholic acidThe drug reduces cholesterol absorption and is used to dissolve (cholesterol) gallstones in patients who want an alternative to surgery.
DB02659Cholic AcidOral cholic acid is indicated for: treatment of bile acid synthesis disorders due to single enzyme defects; and as adjunctive treatment of peroxisomal disorders including Zellweger spectrum disorders in patients who exhibit manifestations of liver disease, steatorrhea or complications from decreased fat soluble vitamin absorption.
DB00977Ethinyl EstradiolFor treatment of moderate to severe vasomotor symptoms associated with the menopause, female hypogonadism, prostatic carcinoma-palliative therapy of advanced disease, breast cancer, as an oral contraceptive, and as emergency contraceptive.
DB01045RifampicinFor the treatment of Tuberculosis and Tuberculosis-related mycobacterial infections.
DB02123Glycochenodeoxycholic AcidNot Available
DB00675TamoxifenTamoxifen is indicated for the treatment of metastatic breast cancer in women and men and ductal carcinoma in Situ.
DB00091CyclosporineFor treatment of transplant (kidney, liver, and heart) rejection, rheumatoid arthritis, severe psoriasis.
DB00845ClofazimineFor the treatment of lepromatous leprosy, including dapsone-resistant lepromatous leprosy and lepromatous leprosy complicated by erythema nodosum leprosum.
DB00206ReserpineFoe the treatment of hypertension
DB00570VinblastineFor treatment of breast cancer, testicular cancer, lymphomas, neuroblastoma, Hodgkin's and non-Hodgkin's lymphomas, mycosis fungoides, histiocytosis, and Kaposi's sarcoma.
DB00477ChlorpromazineFor the treatment of schizophrenia, control nausea and vomiting, For relief of restlessness and apprehension before surgery, adjunct in the treatment of tetanus, control the manifestations of the manic type of manic-depressive illness.
DB00908QuinidineFor the treatment of ventricular pre-excitation and cardiac dysrhythmias
DB00396ProgesteroneFor progesterone supplementation or replacement as part of an Assisted Reproductive Technology (ART) treatment for infertile women with progesterone deficiency and for the treatment of secondary amenorrhea. Also used for the reduction of the incidence of endometrial hyperplasia and the attendant risk of endometrial carcinoma in postmenopausal women receiving estrogen replacement therapy, as well as treatment of abnormal uterine bleeding due to hormonal imbalance in the absence of organic pathology such as fibroids or uterine cancer.
DB01026KetoconazoleFor the treatment of the following systemic fungal infections: candidiasis, chronic mucocutaneous candidiasis, oral thrush, candiduria, blastomycosis, coccidioidomycosis, histoplasmosis, chromomycosis, and paracoccidioidomycosis.
DB00501CimetidineFor the treatment and the management of acid-reflux disorders (GERD), peptic ulcer disease, heartburn, and acid indigestion.
DB00661VerapamilFor the treatment of hypertension, angina, and cluster headache prophylaxis.
DB00197TroglitazoneFor the treatment of Type II diabetes mellitus. It is used alone or in combination with a sulfonylurea, metformin, or insulin as an adjunct to diet and exercise.
DB01229PaclitaxelUsed in the treatment of Kaposi's sarcoma and cancer of the lung, ovarian, and breast. Abraxane® is specfically indicated for the treatment of metastatic breast cancer and locally advanced or metastatic non-small cell lung cancer.
DB02703Fusidic AcidFor the treatment of bacterial infections.
DB00559BosentanUsed in the treatment of pulmonary arterial hypertension (PAH), to improve exercise ability and to decrease the rate of clinical worsening (in patients with WHO Class III or IV symptoms).
DB01051NovobiocinFor the treatment of infections due to staphylococci and other susceptible organisms
DB08901PonatinibPonatinib is indicated for the treatment of adult patients with chronic phase, accelerated phase, or blast phase chronic myeloid leukemia (CML) that is resistant or intolerant to prior tyrosine kinase inhibitor therapy or Philadelphia chromosome positive acute lymphoblastic leukemia (Ph+ALL) that is resistant or intolerant to prior tyrosine kinase inhibitor therapy.
DB06290SimeprevirIndicated for the treatment of adults with chronic hepatitis C virus (HCV) infection: typically in combination with sofosbuvir in patients with HCV genotype 1 without cirrhosis or with compensated cirrhosis and in combination with peginterferon alfa (Peg-IFN-alfa) and ribavirin (RBV) in patients with HCV genotype 1 or 4 without cirrhosis or with compensated cirrhosis. Resistance: Reduced susceptibility to simeprevir was most commonly associated with the viral NS3 Q80K polymorphism. Amino acid substitutions at NS3 positions S122, R155 and/or D168 are also shown to reduce susceptibility to simeprevir in genotype 1a/b patients.
DrugDrug NameTargetType
DB01016GlyburideATP-binding cassette sub-family C member 9target
DB01016GlyburideBile salt export pumptarget
DB01016GlyburideATP-binding cassette sub-family A member 1target
DB01016GlyburideCystic fibrosis transmembrane conductance regulatortarget
DB01016GlyburideSulfonylurea receptor 1, Kir6.2target
DB01016GlyburideG protein-activated inward rectifier potassium channel 4target
DB01016GlyburideCytochrome P450 2C9enzyme
DB01016GlyburideCanalicular multispecific organic anion transporter 2transporter
DB01016GlyburideBile salt export pumptransporter
DB01016GlyburideMultidrug resistance protein 1transporter
DB01016GlyburideMultidrug resistance-associated protein 1transporter
DB01016GlyburideSolute carrier family 15 member 1transporter
DB01016GlyburideSolute carrier organic anion transporter family member 1A2transporter
DB01016GlyburideSolute carrier family 15 member 2transporter
DB01016GlyburideSolute carrier family 22 member 6transporter
DB01016GlyburideCanalicular multispecific organic anion transporter 1transporter
DB01016GlyburideATP-binding cassette sub-family G member 2transporter
DB01016GlyburideSolute carrier family 22 member 7transporter
DB01016GlyburideSolute carrier organic anion transporter family member 2B1transporter
DB01016GlyburideCytochrome P450 2C19enzyme
DB01016GlyburideCytochrome P450 3A4enzyme
DB01016GlyburideSerum albumincarrier
DB01016GlyburideMitochondrial ATP-sensitive potassium channeltarget
DB01016GlyburideCarnitine O-palmitoyltransferase 1, liver isoformtarget
DB01586Ursodeoxycholic acidAldo-keto reductase family 1 member C2target
DB01586Ursodeoxycholic acidBile salt export pumptransporter
DB01586Ursodeoxycholic acidSolute carrier organic anion transporter family member 1A2transporter
DB01586Ursodeoxycholic acidCanalicular multispecific organic anion transporter 1transporter
DB01586Ursodeoxycholic acidMultidrug resistance-associated protein 4transporter
DB01586Ursodeoxycholic acidIleal sodium/bile acid cotransportertransporter
DB01586Ursodeoxycholic acidSodium/bile acid cotransportertransporter
DB01586Ursodeoxycholic acidCytochrome P450 2E1enzyme
DB01586Ursodeoxycholic acidBile acid receptortarget
DB02659Cholic AcidFerrochelatase, mitochondrialtarget
DB02659Cholic AcidBile salt export pumptransporter
DB02659Cholic AcidMultidrug resistance protein 1transporter
DB02659Cholic AcidMultidrug resistance-associated protein 1transporter
DB02659Cholic AcidSolute carrier organic anion transporter family member 1A2transporter
DB02659Cholic AcidIleal sodium/bile acid cotransportertransporter
DB02659Cholic AcidCanalicular multispecific organic anion transporter 1transporter
DB02659Cholic AcidSolute carrier organic anion transporter family member 1B1transporter
DB02659Cholic AcidCanalicular multispecific organic anion transporter 2transporter
DB02659Cholic AcidMultidrug resistance-associated protein 4transporter
DB02659Cholic AcidSodium/bile acid cotransportertransporter
DB02659Cholic AcidSolute carrier family 22 member 8transporter
DB02659Cholic AcidSolute carrier family 22 member 7transporter
DB02659Cholic AcidSolute carrier organic anion transporter family member 1B3transporter
DB02659Cholic AcidAlcohol dehydrogenase 1Ctarget
DB02659Cholic AcidEstrogen-related receptor gammatarget
DB02659Cholic AcidGastrotropintarget
DB02659Cholic AcidCytochrome c oxidase subunit 4 isoform 1, mitochondrialtarget
DB02659Cholic AcidCytochrome c oxidase subunit 1target
DB02659Cholic AcidCytochrome c oxidase subunit 2target
DB02659Cholic AcidCytochrome c oxidase subunit 3target
DB02659Cholic AcidCytochrome c oxidase subunit 5A, mitochondrialtarget
DB02659Cholic AcidCytochrome c oxidase subunit 5B, mitochondrialtarget
DB02659Cholic AcidCytochrome c oxidase subunit 6Ctarget
DB02659Cholic AcidCytochrome c oxidase subunit 7B, mitochondrialtarget
DB02659Cholic AcidCytochrome c oxidase subunit 7C, mitochondrialtarget
DB02659Cholic AcidCytochrome c oxidase subunit 8A, mitochondrialtarget
DB02659Cholic AcidCytochrome c oxidase subunit 6A2, mitochondrialtarget
DB02659Cholic AcidCytochrome c oxidase subunit 6B1target
DB02659Cholic AcidCytochrome c oxidase subunit 7A1, mitochondrialtarget
DB02659Cholic AcidPhospholipase A2target
DB02659Cholic AcidLiver carboxylesterase 1target
DB02659Cholic AcidFatty acid-binding protein, livercarrier
DB02659Cholic AcidFerrochelatasetarget
DB02659Cholic AcidCholoylglycine hydrolasetarget
DB02659Cholic AcidBile acid receptortarget
DB02659Cholic AcidG-protein coupled bile acid receptor 1target
DB00977Ethinyl EstradiolEstrogen receptor alphatarget
DB00977Ethinyl EstradiolNuclear receptor subfamily 1 group I member 2target
DB00977Ethinyl EstradiolCytochrome P450 3A4enzyme
DB00977Ethinyl EstradiolCytochrome P450 2C8enzyme
DB00977Ethinyl EstradiolBile salt export pumptransporter
DB00977Ethinyl EstradiolSodium/bile acid cotransportertransporter
DB00977Ethinyl EstradiolCanalicular multispecific organic anion transporter 1transporter
DB00977Ethinyl EstradiolMultidrug resistance protein 1transporter
DB00977Ethinyl EstradiolSex hormone-binding globulintarget
DB01045RifampicinDNA-directed RNA polymerase subunit betatarget
DB01045RifampicinNuclear receptor subfamily 1 group I member 2target
DB01045RifampicinCytochrome P450 3A4enzyme
DB01045RifampicinCytochrome P450 1A2enzyme
DB01045RifampicinCytochrome P450 2C8enzyme
DB01045RifampicinUDP-glucuronosyltransferase 1-1enzyme
DB01045RifampicinCytochrome P450 2C9enzyme
DB01045RifampicinCytochrome P450 2B6enzyme
DB01045RifampicinCytochrome P450 2C19enzyme
DB01045RifampicinCanalicular multispecific organic anion transporter 2transporter
DB01045RifampicinMultidrug resistance-associated protein 5transporter
DB01045RifampicinMultidrug resistance protein 1transporter
DB01045RifampicinCanalicular multispecific organic anion transporter 1transporter
DB01045RifampicinSolute carrier organic anion transporter family member 2B1transporter
DB01045RifampicinBile salt export pumptransporter
DB01045RifampicinMultidrug resistance-associated protein 1transporter
DB01045RifampicinSolute carrier organic anion transporter family member 1A2transporter
DB01045RifampicinSolute carrier organic anion transporter family member 1B3transporter
DB01045RifampicinSolute carrier family 22 member 7transporter
DB01045RifampicinSolute carrier organic anion transporter family member 1B1transporter
DB01045RifampicinDNA-directed RNA polymerase subunit beta'target
DB01045RifampicinCytochrome P450 2A6enzyme
DB01045RifampicinCytochrome P450 2E1enzyme
DB01045RifampicinCytochrome P450 3A43enzyme
DB01045RifampicinCytochrome P450 3A5enzyme
DB01045RifampicinCytochrome P450 3A7enzyme
DB01045RifampicinCytochrome P450 4A11enzyme
DB01045RifampicinSolute carrier organic anion transporter family member 1B1target
DB01045RifampicinSolute carrier organic anion transporter family member 1A2target
DB01045RifampicinSolute carrier organic anion transporter family member 1B3target
DB01045RifampicinLanosterol 14-alpha demethylasetarget
DB01045RifampicinSerum albumintarget
DB01045RifampicinSolute carrier organic anion transporter family member 2B1target
DB02123Glycochenodeoxycholic Acid7-alpha-hydroxysteroid dehydrogenasetarget
DB02123Glycochenodeoxycholic AcidBile salt export pumptransporter
DB02123Glycochenodeoxycholic AcidSolute carrier organic anion transporter family member 1A2transporter
DB02123Glycochenodeoxycholic AcidIleal sodium/bile acid cotransportertransporter
DB02123Glycochenodeoxycholic AcidSodium/bile acid cotransportertransporter
DB00675TamoxifenEstrogen receptor alphatarget
DB00675TamoxifenEstrogen receptor betatarget
DB00675TamoxifenCytochrome P450 2C9enzyme
DB00675TamoxifenCytochrome P450 3A4enzyme
DB00675TamoxifenCytochrome P450 2D6enzyme
DB00675TamoxifenCytochrome P450 2C8enzyme
DB00675TamoxifenCytochrome P450 2B6enzyme
DB00675TamoxifenLiver carboxylesterase 1enzyme
DB00675TamoxifenCytochrome P450 3A5enzyme
DB00675TamoxifenCytochrome P450 1A1enzyme
DB00675TamoxifenCytochrome P450 1A2enzyme
DB00675TamoxifenCytochrome P450 1B1enzyme
DB00675TamoxifenCytochrome P450 2C19enzyme
DB00675TamoxifenDimethylaniline monooxygenase [N-oxide-forming] 1enzyme
DB00675TamoxifenDimethylaniline monooxygenase [N-oxide-forming] 3enzyme
DB00675TamoxifenCytochrome P450 3A7enzyme
DB00675TamoxifenMultidrug resistance protein 1transporter
DB00675TamoxifenBile salt export pumptransporter
DB00675TamoxifenATP-binding cassette sub-family G member 2transporter
DB00675TamoxifenCytochrome P450 19A1enzyme
DB00675TamoxifenCytochrome P450 2A6enzyme
DB00675TamoxifenCytochrome P450 2E1enzyme
DB00675TamoxifenUDP-glucuronosyltransferase 1-10enzyme
DB00675TamoxifenSulfotransferase 1A1enzyme
DB00675TamoxifenCanalicular multispecific organic anion transporter 1transporter
DB00675Tamoxifen3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerasetarget
DB00675TamoxifenProtein kinase Ctarget
DB00675TamoxifenAndrogen receptortarget
DB00675TamoxifenPotassium voltage-gated channel subfamily H member 2target
DB00675TamoxifenNuclear receptor subfamily 1 group I member 2target
DB00675TamoxifenEstrogen-related receptor gammatarget
DB00675TamoxifenSex hormone-binding globulintarget
DB00091CyclosporineCalcium signal-modulating cyclophilin ligandtarget
DB00091CyclosporinePeptidyl-prolyl cis-trans isomerase Atarget
DB00091CyclosporineCalcineurin subunit B type 2target
DB00091CyclosporineCytochrome P450 3A5enzyme
DB00091CyclosporineCytochrome P450 3A4enzyme
DB00091CyclosporineCytochrome P450 3A7enzyme
DB00091CyclosporineMultidrug resistance protein 1transporter
DB00091CyclosporineCanalicular multispecific organic anion transporter 2transporter
DB00091CyclosporineBile salt export pumptransporter
DB00091CyclosporineMultidrug resistance-associated protein 1transporter
DB00091CyclosporineSolute carrier organic anion transporter family member 1A2transporter
DB00091CyclosporineIleal sodium/bile acid cotransportertransporter
DB00091CyclosporineSodium/bile acid cotransportertransporter
DB00091CyclosporineSolute carrier family 22 member 6transporter
DB00091CyclosporineMultidrug resistance-associated protein 7transporter
DB00091CyclosporineCanalicular multispecific organic anion transporter 1transporter
DB00091CyclosporineATP-binding cassette sub-family G member 2transporter
DB00091CyclosporineSolute carrier organic anion transporter family member 1B1transporter
DB00091CyclosporineCytochrome P450 2C19enzyme
DB00091CyclosporineCytochrome P450 2C8enzyme
DB00091CyclosporineCytochrome P450 2C9enzyme
DB00091CyclosporineCytochrome P450 2D6enzyme
DB00091CyclosporinePeptidyl-prolyl cis-trans isomerase F, mitochondrialtarget
DB00845ClofazimineUncharacterized oxidoreductase CzcO-liketarget
DB00845ClofazimineDNAtarget
DB00845ClofazimineBile salt export pumptransporter
DB00845ClofazimineMultidrug resistance protein 1transporter
DB00845ClofazimineCytochrome P450 3A4enzyme
DB00845ClofazimineBile salt export pumptarget
DB00206ReserpineSynaptic vesicular amine transportertarget
DB00206ReserpineMultidrug resistance protein 1transporter
DB00206ReserpineSolute carrier family 22 member 1transporter
DB00206ReserpineBile salt export pumptransporter
DB00206ReserpineCanalicular multispecific organic anion transporter 1transporter
DB00206ReserpineSolute carrier family 22 member 2transporter
DB00206ReserpineCytochrome P450 3A5enzyme
DB00206ReserpineChromaffin granule amine transportertarget
DB00206ReserpineBaculoviral IAP repeat-containing protein 5target
DB00570VinblastineTubulin beta chaintarget
DB00570VinblastineTranscription factor AP-1target
DB00570VinblastineCytochrome P450 3A4enzyme
DB00570VinblastineMultidrug resistance protein 1transporter
DB00570VinblastineMultidrug resistance-associated protein 1transporter
DB00570VinblastineCanalicular multispecific organic anion transporter 1transporter
DB00570VinblastineMultidrug resistance-associated protein 6transporter
DB00570VinblastineBile salt export pumptransporter
DB00570VinblastineSolute carrier family 22 member 2transporter
DB00570VinblastineTubulin alpha-1A chaintarget
DB00570VinblastineTubulin delta chaintarget
DB00570VinblastineTubulin epsilon chaintarget
DB00570VinblastineTubulin gamma-1 chaintarget
DB00570VinblastineCytochrome P450 2D6enzyme
DB00477ChlorpromazineD(2) dopamine receptortarget
DB00477Chlorpromazine5-hydroxytryptamine receptor 2Atarget
DB00477ChlorpromazineCytochrome P450 2D6enzyme
DB00477ChlorpromazineCholinesteraseenzyme
DB00477ChlorpromazineCytochrome P450 1A2enzyme
DB00477ChlorpromazineSerum albumincarrier
DB00477ChlorpromazineSolute carrier family 22 member 1transporter
DB00477ChlorpromazineBile salt export pumptransporter
DB00477ChlorpromazineMultidrug resistance protein 1transporter
DB00477ChlorpromazineD(1A) dopamine receptortarget
DB00477Chlorpromazine5-hydroxytryptamine receptor 1Atarget
DB00477ChlorpromazineAlpha-1A adrenergic receptortarget
DB00477ChlorpromazineAlpha-1B adrenergic receptortarget
DB00477ChlorpromazineCytochrome P450 2E1enzyme
DB00477ChlorpromazineCytochrome P450 3A4enzyme
DB00477ChlorpromazineHistamine H1 receptortarget
DB00477ChlorpromazinePotassium voltage-gated channel subfamily H member 2target
DB00477ChlorpromazineD(1) dopamine receptortarget
DB00477ChlorpromazineD(3) dopamine receptortarget
DB00477ChlorpromazineD(4) dopamine receptortarget
DB00477ChlorpromazineD(1B) dopamine receptortarget
DB00477Chlorpromazine5-hydroxytryptamine receptor 2Ctarget
DB00477Chlorpromazine5-hydroxytryptamine 2 receptortarget
DB00477ChlorpromazineAlpha-1 adrenergic receptorstarget
DB00477ChlorpromazineAlpha-2 adrenergic receptorstarget
DB00477ChlorpromazineMuscarinic acetylcholine receptor M1target
DB00477ChlorpromazineMuscarinic acetylcholine receptor M3target
DB00477ChlorpromazineSphingomyelin phosphodiesterasetarget
DB00477ChlorpromazineCalmodulintarget
DB00477Chlorpromazinealpha1-acid glycoproteintarget
DB00477Chlorpromazine5-hydroxytryptamine receptor 6target
DB00477Chlorpromazine5-hydroxytryptamine receptor 7target
DB00477ChlorpromazineHistamine H4 receptortarget
DB00908QuinidineSodium channel protein type 5 subunit alphatarget
DB00908QuinidineAlpha-1-acid glycoprotein 1carrier
DB00908QuinidinePotassium voltage-gated channel subfamily H member 2target
DB00908QuinidinePotassium channel subfamily K member 1target
DB00908QuinidinePotassium channel subfamily K member 6target
DB00908QuinidineCytochrome P450 1A2enzyme
DB00908QuinidineCytochrome P450 2E1enzyme
DB00908QuinidineCytochrome P450 1A1enzyme
DB00908QuinidineCytochrome P450 2D6enzyme
DB00908QuinidineCytochrome P450 3A4enzyme
DB00908QuinidineCytochrome P450 3A7enzyme
DB00908QuinidineSolute carrier family 22 member 2transporter
DB00908QuinidineSolute carrier family 22 member 1transporter
DB00908QuinidineSolute carrier family 22 member 5transporter
DB00908QuinidineBile salt export pumptransporter
DB00908QuinidineMultidrug resistance protein 1transporter
DB00908QuinidineSolute carrier organic anion transporter family member 1A2transporter
DB00908QuinidineSolute carrier family 22 member 8transporter
DB00908QuinidineCanalicular multispecific organic anion transporter 1transporter
DB00908QuinidineSolute carrier family 22 member 4transporter
DB00908QuinidineSolute carrier organic anion transporter family member 1B1transporter
DB00908QuinidineCytochrome P450 2B6enzyme
DB00908QuinidineCytochrome P450 2C8enzyme
DB00908QuinidineCytochrome P450 2C9enzyme
DB00908QuinidineAlpha-1A adrenergic receptortarget
DB00908QuinidineAlpha-1B adrenergic receptortarget
DB00908QuinidineAlpha-1D adrenergic receptortarget
DB00396ProgesteroneProgesterone receptortarget
DB00396ProgesteroneEstrogen receptor alphatarget
DB00396ProgesteroneSteroid 17-alpha-hydroxylase/17,20 lyasetarget
DB00396ProgesteroneCytochrome P450 2C19enzyme
DB00396ProgesteroneCytochrome P450 2C9enzyme
DB00396ProgesteroneCytochrome P450 3A4enzyme
DB00396ProgesteroneCytochrome P450 3A5enzyme
DB00396ProgesteroneCytochrome P450 3A7enzyme
DB00396ProgesteroneMultidrug resistance protein 1transporter
DB00396ProgesteroneSolute carrier family 22 member 2transporter
DB00396ProgesteroneSolute carrier family 22 member 1transporter
DB00396ProgesteroneSolute carrier family 22 member 3transporter
DB00396ProgesteroneBile salt export pumptransporter
DB00396ProgesteroneMultidrug resistance-associated protein 1transporter
DB00396ProgesteroneSodium/bile acid cotransportertransporter
DB00396ProgesteroneSteroid 17-alpha-hydroxylase/17,20 lyaseenzyme
DB00396ProgesteroneCytochrome P450 1A1enzyme
DB00396ProgesteroneCytochrome P450 1A2enzyme
DB00396ProgesteroneCytochrome P450 1B1enzyme
DB00396ProgesteroneCytochrome P450 2A6enzyme
DB00396ProgesteroneCytochrome P450 2C8enzyme
DB00396ProgesteroneCytochrome P450 2D6enzyme
DB00396ProgesteroneMineralocorticoid receptortarget
DB00396ProgesteroneKappa-type opioid receptortarget
DB00396ProgesteroneNuclear receptor subfamily 1 group I member 2target
DB00396ProgesteroneAlpha-1-acid glycoprotein 1target
DB00396ProgesteroneGlucocorticoid receptortarget
DB00396ProgesteroneAndrogen receptortarget
DB00396ProgesteroneSex hormone-binding globulintarget
DB01026KetoconazoleCytochrome P450 3A4enzyme
DB01026KetoconazoleCytochrome P450 2C9enzyme
DB01026KetoconazoleCytochrome P450 2C19enzyme
DB01026KetoconazoleCytochrome P450 3A5enzyme
DB01026KetoconazoleCytochrome P450 1A2enzyme
DB01026KetoconazoleCytochrome P450 2C8enzyme
DB01026KetoconazoleCytochrome P450 1A1enzyme
DB01026KetoconazoleCytochrome P450 2D6enzyme
DB01026KetoconazoleCytochrome P450 3A7enzyme
DB01026KetoconazoleBile salt export pumptransporter
DB01026KetoconazoleMultidrug resistance protein 1transporter
DB01026KetoconazoleSolute carrier organic anion transporter family member 1A2transporter
DB01026KetoconazoleCholesterol side-chain cleavage enzyme, mitochondrialenzyme
DB01026KetoconazoleCytochrome P450 11B1, mitochondrialenzyme
DB01026KetoconazoleCytochrome P450 1B1enzyme
DB01026KetoconazoleCytochrome P450 26A1enzyme
DB01026KetoconazoleCytochrome P450 2A6enzyme
DB01026KetoconazoleCytochrome P450 2B6enzyme
DB01026KetoconazoleLanosterol 14-alpha demethylaseenzyme
DB01026KetoconazoleLanosterol 14-alpha demethylasetarget
DB01026KetoconazoleAndrogen receptortarget
DB01026Ketoconazole17-hydroxylasetarget
DB01026KetoconazoleSteroid 21-hydroxylasetarget
DB01026Ketoconazole11-hydroxylasetarget
DB01026KetoconazoleCytochrome P450 19A1target
DB01026KetoconazolePotassium voltage-gated channel subfamily H member 2target
DB01026KetoconazoleNuclear receptor subfamily 1 group I member 2target
DB01026KetoconazoleNuclear receptor subfamily 1 group I member 3target
DB00501CimetidineHistamine H2 receptortarget
DB00501CimetidineCytochrome P450 1A2enzyme
DB00501CimetidineCytochrome P450 2D6enzyme
DB00501CimetidineCytochrome P450 2C19enzyme
DB00501CimetidineCytochrome P450 3A4enzyme
DB00501CimetidineCytochrome P450 3A5enzyme
DB00501CimetidineCytochrome P450 3A7enzyme
DB00501CimetidineMultidrug resistance protein 1transporter
DB00501CimetidineSolute carrier family 22 member 2transporter
DB00501CimetidineSolute carrier family 22 member 1transporter
DB00501CimetidineSolute carrier family 22 member 3transporter
DB00501CimetidineSolute carrier family 22 member 5transporter
DB00501CimetidineBile salt export pumptransporter
DB00501CimetidineSolute carrier family 22 member 6transporter
DB00501CimetidineSolute carrier family 22 member 8transporter
DB00501CimetidineMultidrug and toxin extrusion protein 1transporter
DB00501CimetidineSolute carrier family 22 member 4transporter
DB00501CimetidineSolute carrier family 22 member 11transporter
DB00501CimetidineSolute carrier family 22 member 7transporter
DB00501CimetidineCytochrome P450 11B1, mitochondrialenzyme
DB00501CimetidineCytochrome P450 2C8enzyme
DB00501CimetidineCytochrome P450 2C9enzyme
DB00501CimetidineCytochrome P450 2E1enzyme
DB00501CimetidineDimethylaniline monooxygenase [N-oxide-forming] 3enzyme
DB00501CimetidineDimethylaniline monooxygenase [N-oxide-forming] 1enzyme
DB00661VerapamilSodium channel protein type 5 subunit alphatarget
DB00661VerapamilATP-sensitive inward rectifier potassium channel 11target
DB00661VerapamilVoltage-dependent L-type calcium channel subunit beta-4target
DB00661VerapamilVoltage-dependent T-type calcium channel subunit alpha-1Gtarget
DB00661VerapamilVoltage-dependent L-type calcium channel subunit alpha-1Ftarget
DB00661VerapamilVoltage-dependent L-type calcium channel subunit beta-3target
DB00661VerapamilVoltage-dependent L-type calcium channel subunit alpha-1Dtarget
DB00661VerapamilVoltage-dependent L-type calcium channel subunit beta-1target
DB00661VerapamilVoltage-dependent L-type calcium channel subunit beta-2target
DB00661VerapamilPotassium voltage-gated channel subfamily H member 2target
DB00661VerapamilVoltage-dependent L-type calcium channel subunit alpha-1Starget
DB00661VerapamilVoltage-dependent L-type calcium channel subunit alpha-1Ctarget
DB00661VerapamilVoltage-dependent T-type calcium channel subunit alpha-1Itarget
DB00661VerapamilCytochrome P450 1A2enzyme
DB00661VerapamilCytochrome P450 3A5enzyme
DB00661VerapamilVoltage-dependent N-type calcium channel subunit alpha-1Btarget
DB00661VerapamilVoltage-dependent P/Q-type calcium channel subunit alpha-1Atarget
DB00661VerapamilSodium-dependent serotonin transportertarget
DB00661VerapamilCytochrome P450 3A4enzyme
DB00661VerapamilCytochrome P450 3A7enzyme
DB00661VerapamilMultidrug resistance protein 1transporter
DB00661VerapamilSolute carrier family 22 member 1transporter
DB00661VerapamilCanalicular multispecific organic anion transporter 2transporter
DB00661VerapamilMultidrug resistance-associated protein 4transporter
DB00661VerapamilSolute carrier family 22 member 5transporter
DB00661VerapamilBile salt export pumptransporter
DB00661VerapamilMultidrug resistance-associated protein 1transporter
DB00661VerapamilSolute carrier organic anion transporter family member 1A2transporter
DB00661VerapamilMultidrug resistance-associated protein 7transporter
DB00661VerapamilCanalicular multispecific organic anion transporter 1transporter
DB00661VerapamilSolute carrier family 22 member 4transporter
DB00661VerapamilATP-binding cassette sub-family G member 2transporter
DB00661VerapamilSolute carrier organic anion transporter family member 1B1transporter
DB00661VerapamilCytochrome P450 2C8enzyme
DB00661VerapamilCytochrome P450 2C9enzyme
DB00661VerapamilCytochrome P450 2C18enzyme
DB00661VerapamilCytochrome P450 2B6enzyme
DB00661VerapamilCytochrome P450 2C19enzyme
DB00661VerapamilCytochrome P450 2D6enzyme
DB00661VerapamilAlpha-1A adrenergic receptortarget
DB00661VerapamilAlpha-1B adrenergic receptortarget
DB00661VerapamilAlpha-1D adrenergic receptortarget
DB00197TroglitazonePeroxisome proliferator-activated receptor gammatarget
DB00197TroglitazoneLong-chain-fatty-acid--CoA ligase 4target
DB00197TroglitazonePlasminogen activator inhibitor 1target
DB00197TroglitazoneEquilibrative nucleoside transporter 1target
DB00197TroglitazoneCytochrome P450 3A4enzyme
DB00197TroglitazoneCytochrome P450 2C19enzyme
DB00197TroglitazoneUDP-glucuronosyltransferase 1-1enzyme
DB00197TroglitazoneCytochrome P450 2C8enzyme
DB00197TroglitazoneBile salt export pumptransporter
DB00197TroglitazoneSolute carrier organic anion transporter family member 1B1transporter
DB00197TroglitazoneEstrogen-related receptor gammatarget
DB00197TroglitazoneSteroid hormone receptor ERR1target
DB00197TroglitazoneCytochrome P450 19A1enzyme
DB00197TroglitazoneCytochrome P450 1A1enzyme
DB00197TroglitazoneCytochrome P450 2B6enzyme
DB00197TroglitazoneCytochrome P450 2C9enzyme
DB00197TroglitazoneCytochrome P450 3A5enzyme
DB00197TroglitazoneCytochrome P450 3A7enzyme
DB00197TroglitazoneUDP-glucuronosyltransferase 1-3enzyme
DB00197TroglitazoneUDP-glucuronosyltransferase 1-4enzyme
DB00197TroglitazoneUDP-glucuronosyltransferase 1-6enzyme
DB00197TroglitazoneUDP-glucuronosyltransferase 1-7enzyme
DB00197TroglitazoneUDP-glucuronosyltransferase 1-8enzyme
DB00197TroglitazoneUDP-glucuronosyltransferase 1-9enzyme
DB00197TroglitazoneUDP-glucuronosyltransferase 1-10enzyme
DB00197TroglitazoneUDP-glucuronosyltransferase 2B7enzyme
DB00197TroglitazoneUDP-glucuronosyltransferase 2B15enzyme
DB00197TroglitazonePeroxisome proliferator-activated receptor deltatarget
DB00197TroglitazonePeroxisome proliferator-activated receptor alphatarget
DB00197TroglitazoneGlutathione S-transferase Ptarget
DB01229PaclitaxelApoptosis regulator Bcl-2target
DB01229PaclitaxelTubulin beta-1 chaintarget
DB01229PaclitaxelCytochrome P450 2C8enzyme
DB01229PaclitaxelCytochrome P450 3A4enzyme
DB01229PaclitaxelCytochrome P450 3A5enzyme
DB01229PaclitaxelCytochrome P450 3A7enzyme
DB01229PaclitaxelCytochrome P450 2C9enzyme
DB01229PaclitaxelBile salt export pumptransporter
DB01229PaclitaxelMultidrug resistance protein 1transporter
DB01229PaclitaxelMultidrug resistance-associated protein 1transporter
DB01229PaclitaxelMultidrug resistance-associated protein 7transporter
DB01229PaclitaxelCytochrome P450 19A1enzyme
DB01229PaclitaxelCytochrome P450 1B1enzyme
DB01229PaclitaxelSolute carrier organic anion transporter family member 1B3transporter
DB01229PaclitaxelNuclear receptor subfamily 1 group I member 2target
DB01229PaclitaxelMicrotubule-associated protein 4target
DB01229PaclitaxelMicrotubule-associated protein 2target
DB01229PaclitaxelMicrotubule-associated protein tautarget
DB01229PaclitaxelATP-binding cassette sub-family G member 2transporter
DB01229PaclitaxelCanalicular multispecific organic anion transporter 1transporter
DB02703Fusidic AcidChloramphenicol acetyltransferase 3target
DB02703Fusidic AcidChloramphenicol acetyltransferasetarget
DB02703Fusidic AcidBile salt export pumptransporter
DB02703Fusidic AcidCanalicular multispecific organic anion transporter 1transporter
DB02703Fusidic AcidElongation factor Gtarget
DB00559BosentanEndothelin B receptortarget
DB00559BosentanEndothelin-1 receptortarget
DB00559BosentanCytochrome P450 3A4enzyme
DB00559BosentanCytochrome P450 2C9enzyme
DB00559BosentanBile salt export pumptransporter
DB01051NovobiocinDNA gyrase subunit Btarget
DB01051NovobiocinBile salt export pumptransporter
DB01051NovobiocinSolute carrier family 22 member 6transporter
DB01051NovobiocinSolute carrier family 22 member 8transporter
DB01051NovobiocinSolute carrier family 22 member 11transporter
DB01051NovobiocinATP-binding cassette sub-family G member 2transporter
DB01051NovobiocinDNA topoisomerase 1target
DB08901PonatinibTyrosine-protein kinase ABL1target
DB08901PonatinibBreakpoint cluster region proteintarget
DB08901PonatinibMast/stem cell growth factor receptor Kittarget
DB08901PonatinibProto-oncogene tyrosine-protein kinase receptor Rettarget
DB08901PonatinibAngiopoietin-1 receptortarget
DB08901PonatinibReceptor-type tyrosine-protein kinase FLT3target
DB08901PonatinibCytochrome P450 3A4enzyme
DB08901PonatinibCytochrome P450 2C8enzyme
DB08901PonatinibCytochrome P450 2D6enzyme
DB08901PonatinibCytochrome P450 3A5enzyme
DB08901PonatinibMultidrug resistance protein 1transporter
DB08901PonatinibATP-binding cassette sub-family G member 2transporter
DB08901PonatinibFibroblast growth factor receptor 1target
DB08901PonatinibFibroblast growth factor receptor 2target
DB08901PonatinibFibroblast growth factor receptor 3target
DB08901PonatinibFibroblast growth factor receptor 4target
DB08901PonatinibTyrosine-protein kinase Lcktarget
DB08901PonatinibProto-oncogene tyrosine-protein kinase Srctarget
DB08901PonatinibTyrosine-protein kinase Lyntarget
DB08901PonatinibVascular endothelial growth factor receptor 2target
DB08901PonatinibPlatelet-derived growth factor receptor alphatarget
DB08901PonatinibBile salt export pumptransporter
DB06290SimeprevirNS3 proteasetarget
DB06290SimeprevirSerum albumincarrier
DB06290SimeprevirCytochrome P450 1A2enzyme
DB06290SimeprevirMultidrug resistance protein 1transporter
DB06290SimeprevirSolute carrier organic anion transporter family member 1B1transporter
DB06290SimeprevirSolute carrier organic anion transporter family member 1B3transporter
DB06290SimeprevirCYP3Aenzyme
DB06290SimeprevirCytochrome P450 3A4enzyme
DB06290SimeprevirCanalicular multispecific organic anion transporter 1transporter
DB06290SimeprevirATP-binding cassette sub-family G member 2transporter
DB06290SimeprevirSolute carrier organic anion transporter family member 2B1transporter
DB06290SimeprevirSodium/bile acid cotransportertransporter
DB06290SimeprevirBile salt export pumptransporter