Vitamins (Fat Soluble)

DrugDrug NameDrug Description
DB00162Vitamin AA vitamin important for retinal function that is used clinically to correct vitamin A deficiency.
DB00163Vitamin EAn antioxidant vitamin used in many skin creams and multivitamin preparations.
DB01022PhylloquinoneA fat soluble vitamin used to treat hemorrhagic conditions in infants and coumarin overdoses.
DB00136CalcitriolAn active metabolite of vitamin D that is used to treat hyperparathyroidism and is also used in dialysis patients to combat hypocalcemia.
DB00170MenadioneThe primary known function of vitamin K is to assist in the normal clotting of blood, but it may also play a role in normal bone calcification.
DB11251TocopherolTocopherol can be used as a dietary supplement for patients with a deficit of vitamin E; this is mainly prescribed in the alpha form. Vitamin E deficiency is rare, and...
DB12647TocotrienolTocotrienol has been investigated for the treatment of Cholesterol Lowering.
DB14001alpha-Tocopherol succinateA form of vitamin E used to treat and prevent vitamin deficiencies.
DB14002D-alpha-Tocopherol acetateA form of vitamin E used to treat and prevent vitamin deficiencies.
DB14003alpha-Tocopherol acetateA form of vitamin E used to treat and prevent vitamin deficiencies.
DB11635TocofersolanA derivative of alpha tocopherol used to treat vitamin E deficiencies.
DB14476DL-alpha-TocopherolNot Annotated
DB12148MenatetrenoneMenatetrenone has been used in trials studying the treatment of Diabetes, Osteoporosis, Prediabetic State, and Hepatocellular Carcinoma.
DB13075Menaquinone 7Menaquinone 7 is under investigation in clinical trial NCT00402974 (The Effect of Vitamin K Supplementation on Osteocalcin Carboxylation in Healthy Children).
DB00523AlitretinoinA vitamin A derivative used to treat Kaposi's sarcoma and used off label to treat chronic hand eczema and psoriasis.
DB00755TretinoinA vitamin A derivative used to treat acne vulgaris, certain types of promyelocytic leukemia, and fine wrinkles.
DB13368MotretinideNot Annotated
DB06755Beta caroteneA vitamin A precursor found in various nutritional supplements and health products.
DB1409713-cis-12-(3'-Carboxyphenyl)retinoic acidNot Annotated
DB06410DoxercalciferolA synthetic vitamin D2 analog used to treat secondary hyperparathyroidism in patients with chronic kidney disease with or without therapy of dialysis.
DB00910ParicalcitolA vitamin D analog used to treat hyperparathyroidism associated with stage 3 or greater chronic kidney disease.
DB04258SeocalcitolNot Available
DB04796InecalcitolInvestigated for use/treatment in prostate cancer, psoriasis and hyperparathyroidism.
DB04891BecocalcidiolFor topical treatment of psoriasis and psoriatic disorders.
DB05295EldecalcitolInvestigated for use/treatment in osteoporosis.
DB06194ElocalcitolInvestigated for use/treatment in benign prostatic hyperplasia, urinary incontinence, prostate disorders, and infertility.
DB06272MaxacalcitolNot Annotated
DB130971alpha-Hydroxyvitamin D51alpha-Hydroxyvitamin D5 (CARD-024) has been used in trials studying the treatment of Drug Safety and Heart; Disease, Activity.
DB13689TacalcitolNot Annotated
DB00146CalcifediolAn active metabolite of vitamin D used to treat hyperparathyroidism as well as to combat hypocalcemia in dialysis patients.
DB00153ErgocalciferolA vitamin found in many supplement products.
DB01070DihydrotachysterolA synthetic analog of vitamin D that does not require renal activation like vitamin D2 or Vitamin D3.
DB02300CalcipotriolA topical synthetic vitamin D2 derivative used in the treatment of plaque psoriasis.
DB11094Vitamin DAn ingredient found in a variety of supplements and vitamins.
DB00169CholecalciferolA form of Vitamin D used in the treatment of specific medical conditions such as refractory rickets, hypoparathyroidism, and familial hypophosphatemia, as well as osteoporosis and chronic kidney disease.
DB01436AlfacalcidolA vitamin D analogue used for the management of hypocalcemia, secondary hyperparathyroidism, and osteodystrophy in patients with chronic renal failure.
DB15394gamma-Tocopherolgamma-Tocopherol is under investigation in clinical trial NCT00836368 (In Vitro Basophil Responsiveness to Allergen Challenge After Gamma-tocopherol Supplementation in Allergic Asthmatics).
DB14936Menaquinone 6Menaquinone 6 is under investigation in clinical trial NCT01194778 (Comparison of Efficacy of Different Dosages Vitamin K2).
DB15381MenaquinoneMenaquinone is under investigation in clinical trial NCT01533441 (Vitamin K2 Intervention in Patients With Vitamin K Antagonists).
DB061171alpha,24S-Dihydroxyvitamin D2Investigated for use/treatment in parathyroid disorders.
DB1555724-Homo-1,25-dihydroxyvitamin D324-Homo-1,25-dihydroxyvitamin D3 is a novel vitamin D analogue.
DrugDrug NameTargetType
DB00162Vitamin ARetinol dehydrogenase 12target
DB00162Vitamin ARetinol-binding protein 1target
DB00162Vitamin A11-cis retinol dehydrogenasetarget
DB00162Vitamin ARetinol dehydrogenase 13target
DB00162Vitamin ARetinol-binding protein 3target
DB00162Vitamin ARetinol-binding protein 5carrier
DB00162Vitamin ARetinoid-binding protein 7carrier
DB00162Vitamin ARetinol-binding protein 4carrier
DB00162Vitamin ARetinol-binding protein 2carrier
DB00162Vitamin ARetinal dehydrogenase 2target
DB00162Vitamin ARetinal dehydrogenase 1target
DB00162Vitamin ARetinaldehyde-binding protein 1target
DB00162Vitamin ALecithin retinol acyltransferasetarget
DB00162Vitamin AShort-chain dehydrogenase/reductase 3target
DB00162Vitamin AAldehyde dehydrogenase family 1 member A3target
DB00162Vitamin AAll-trans-retinol 13,14-reductasetarget
DB00162Vitamin ARetinol dehydrogenase 11target
DB00162Vitamin ADehydrogenase/reductase SDR family member 4target
DB00162Vitamin ARetinol dehydrogenase 14target
DB00162Vitamin ARetinol dehydrogenase 8target
DB00162Vitamin ACytochrome P450 26A1enzyme
DB00162Vitamin AApolipoprotein Dtarget
DB00162Vitamin AHematopoietic prostaglandin D synthasetarget
DB00162Vitamin ASerum albumincarrier
DB00163Vitamin ESEC14-like protein 4target
DB00163Vitamin ESEC14-like protein 3target
DB00163Vitamin ESEC14-like protein 2target
DB00163Vitamin ENuclear receptor subfamily 1 group I member 2target
DB00163Vitamin EProtein kinase C beta typetarget
DB00163Vitamin EArachidonate 5-lipoxygenasetarget
DB00163Vitamin EProtein kinase C alpha typetarget
DB00163Vitamin EDiacylglycerol kinase alphatarget
DB00163Vitamin ESerine/threonine-protein phosphatase 2A catalytic subunit beta isoformtarget
DB00163Vitamin ESerine/threonine-protein phosphatase 2A catalytic subunit alpha isoformtarget
DB00163Vitamin EAlpha-tocopherol transfer proteincarrier
DB00163Vitamin EGlutathione S-transferase A2enzyme
DB00163Vitamin EGlutathione S-transferase Penzyme
DB00163Vitamin EGlutathione S-transferase omega-1enzyme
DB00163Vitamin EGlutathione S-transferase Mu 3enzyme
DB00163Vitamin EGlutamate--cysteine ligase catalytic subunitenzyme
DB00163Vitamin ENAD(P)H dehydrogenase [quinone] 1enzyme
DB00163Vitamin EHeme oxygenase 1enzyme
DB00163Vitamin ESuperoxide dismutase [Cu-Zn]enzyme
DB00163Vitamin EScavenger receptor class B member 1transporter
DB00163Vitamin EATP-binding cassette sub-family A member 1transporter
DB00163Vitamin ENiemann-Pick C1-like protein 1transporter
DB00163Vitamin EATP-binding cassette sub-family G member 1transporter
DB00163Vitamin ESEC14-like protein 2carrier
DB00163Vitamin ESEC14-like protein 3carrier
DB00163Vitamin EPhospholipid transfer proteincarrier
DB00163Vitamin ECytochrome P450 3A4enzyme
DB01022PhylloquinoneVitamin K-dependent gamma-carboxylasetarget
DB01022PhylloquinoneOsteocalcintarget
DB00136CalcitriolVitamin D3 receptortarget
DB00136Calcitriol1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrialenzyme
DB00136CalcitriolCytochrome P450 3A4enzyme
DB00136CalcitriolHomeobox protein Hox-A10target
DB00136CalcitriolVitamin D-binding proteincarrier
DB00170MenadioneVitamin K-dependent protein Ztarget
DB00170MenadioneProthrombintarget
DB00170MenadioneVitamin K epoxide reductase complex subunit 1target
DB00170MenadioneCoagulation factor IXtarget
DB00170MenadioneCoagulation factor VIItarget
DB00170MenadioneCoagulation factor Xtarget
DB00170MenadioneVitamin K-dependent gamma-carboxylasetarget
DB00170MenadioneVitamin K-dependent protein Ctarget
DB00170MenadioneVitamin K-dependent protein Starget
DB00170MenadioneNAD(P)H dehydrogenase [quinone] 1target
DB00170MenadioneRibosyldihydronicotinamide dehydrogenase [quinone]target
DB00170MenadioneVitamin K epoxide reductase complex subunit 1-like protein 1target
DB00170MenadioneXanthine dehydrogenase/oxidaseenzyme
DB00170MenadioneAldehyde oxidaseenzyme
DB00170MenadioneMethylenetetrahydrofolate reductaseenzyme
DB00170MenadioneCytochrome P450 1A1enzyme
DB00170MenadioneOsteocalcintarget
DB00170MenadioneCytochrome P450 1A2enzyme
DB00170MenadioneCytochrome P450 2A6enzyme
DB11251TocopherolFree radicalstarget
DB11251TocopherolLeukotriene-B(4) omega-hydroxylase 1enzyme
DB11251TocopherolCytochrome P450 3A4enzyme
DB11251TocopherolVery low-density lipoprotein receptorcarrier
DB11251TocopherolLow-density lipoprotein receptorcarrier
DB11251TocopherolAlpha-tocopherol transfer proteintransporter
DB11251TocopherolSEC14-like protein 4transporter
DB11251TocopherolSEC14-like protein 2transporter
DB11251TocopherolSEC14-like protein 3transporter
DB11251TocopherolApolipoprotein B receptortransporter
DB11251TocopherolScavenger receptor class B member 1transporter
DB11251TocopherolP-glycoprotein 1transporter
DB14001alpha-Tocopherol succinateSEC14-like protein 4target
DB14001alpha-Tocopherol succinateSEC14-like protein 3target
DB14001alpha-Tocopherol succinateSEC14-like protein 2target
DB14001alpha-Tocopherol succinateNuclear receptor subfamily 1 group I member 2target
DB14001alpha-Tocopherol succinateProtein kinase C beta typetarget
DB14001alpha-Tocopherol succinateArachidonate 5-lipoxygenasetarget
DB14001alpha-Tocopherol succinateProtein kinase C alpha typetarget
DB14001alpha-Tocopherol succinateDiacylglycerol kinase alphatarget
DB14001alpha-Tocopherol succinateSerine/threonine-protein phosphatase 2A catalytic subunit beta isoformtarget
DB14001alpha-Tocopherol succinateSerine/threonine-protein phosphatase 2A catalytic subunit alpha isoformtarget
DB14001alpha-Tocopherol succinateAlpha-tocopherol transfer proteincarrier
DB14001alpha-Tocopherol succinateGlutathione S-transferase A2enzyme
DB14001alpha-Tocopherol succinateGlutathione S-transferase Penzyme
DB14001alpha-Tocopherol succinateGlutathione S-transferase omega-1enzyme
DB14001alpha-Tocopherol succinateGlutathione S-transferase Mu 3enzyme
DB14001alpha-Tocopherol succinateGlutamate--cysteine ligase catalytic subunitenzyme
DB14001alpha-Tocopherol succinateNAD(P)H dehydrogenase [quinone] 1enzyme
DB14001alpha-Tocopherol succinateHeme oxygenase 1enzyme
DB14001alpha-Tocopherol succinateSuperoxide dismutase [Cu-Zn]enzyme
DB14001alpha-Tocopherol succinateLung epithelial cellstarget
DB14002D-alpha-Tocopherol acetateSEC14-like protein 4target
DB14002D-alpha-Tocopherol acetateSEC14-like protein 3target
DB14002D-alpha-Tocopherol acetateSEC14-like protein 2target
DB14002D-alpha-Tocopherol acetateNuclear receptor subfamily 1 group I member 2target
DB14002D-alpha-Tocopherol acetateProtein kinase C beta typetarget
DB14002D-alpha-Tocopherol acetateArachidonate 5-lipoxygenasetarget
DB14002D-alpha-Tocopherol acetateProtein kinase C alpha typetarget
DB14002D-alpha-Tocopherol acetateDiacylglycerol kinase alphatarget
DB14002D-alpha-Tocopherol acetateSerine/threonine-protein phosphatase 2A catalytic subunit beta isoformtarget
DB14002D-alpha-Tocopherol acetateSerine/threonine-protein phosphatase 2A catalytic subunit alpha isoformtarget
DB14002D-alpha-Tocopherol acetateAlpha-tocopherol transfer proteincarrier
DB14002D-alpha-Tocopherol acetateGlutathione S-transferase A2enzyme
DB14002D-alpha-Tocopherol acetateGlutathione S-transferase Penzyme
DB14002D-alpha-Tocopherol acetateGlutathione S-transferase omega-1enzyme
DB14002D-alpha-Tocopherol acetateGlutathione S-transferase Mu 3enzyme
DB14002D-alpha-Tocopherol acetateGlutamate--cysteine ligase catalytic subunitenzyme
DB14002D-alpha-Tocopherol acetateNAD(P)H dehydrogenase [quinone] 1enzyme
DB14002D-alpha-Tocopherol acetateHeme oxygenase 1enzyme
DB14002D-alpha-Tocopherol acetateSuperoxide dismutase [Cu-Zn]enzyme
DB14003alpha-Tocopherol acetateLeukotriene-B(4) omega-hydroxylase 1enzyme
DB14003alpha-Tocopherol acetateCytochrome P450 3A4enzyme
DB14003alpha-Tocopherol acetateFree radicalstarget
DB14003alpha-Tocopherol acetateAlpha-tocopherol transfer proteintransporter
DB14003alpha-Tocopherol acetateSEC14-like protein 4transporter
DB14003alpha-Tocopherol acetateSEC14-like protein 2transporter
DB14003alpha-Tocopherol acetateSEC14-like protein 3transporter
DB14003alpha-Tocopherol acetateApolipoprotein B receptortransporter
DB14003alpha-Tocopherol acetateScavenger receptor class B member 1transporter
DB14003alpha-Tocopherol acetateP-glycoprotein 1transporter
DB14003alpha-Tocopherol acetateVery low-density lipoprotein receptorcarrier
DB14003alpha-Tocopherol acetateLow-density lipoprotein receptorcarrier
DB11635TocofersolanP-glycoprotein 1target
DB11635TocofersolanLeukotriene-B(4) omega-hydroxylase 1enzyme
DB11635TocofersolanAlpha-tocopherol transfer proteintransporter
DB11635TocofersolanScavenger receptor class B member 1transporter
DB11635TocofersolanNiemann-Pick C1-like protein 1transporter
DB11635TocofersolanATP-binding cassette sub-family G member 5transporter
DB11635TocofersolanATP-binding cassette sub-family G member 8transporter
DB11635TocofersolanATP-binding cassette sub-family A member 1transporter
DB11635TocofersolanSEC14-like protein 4transporter
DB11635TocofersolanSEC14-like protein 2transporter
DB11635TocofersolanSEC14-like protein 3transporter
DB11635TocofersolanApolipoprotein B receptortransporter
DB11635TocofersolanCytochrome P450 3A4enzyme
DB00523AlitretinoinRetinoic acid receptor alphatarget
DB00523AlitretinoinRetinoic acid receptor RXR-betatarget
DB00523AlitretinoinRetinoic acid receptor gammatarget
DB00523AlitretinoinRetinoic acid receptor betatarget
DB00523AlitretinoinRetinoic acid receptor RXR-gammatarget
DB00523AlitretinoinRetinoic acid receptor RXR-alphatarget
DB00523AlitretinoinCellular retinoic acid-binding protein 2carrier
DB00523AlitretinoinCellular retinoic acid-binding protein 1carrier
DB00523AlitretinoinP-glycoprotein 1transporter
DB00523AlitretinoinInsulin-like growth factor-binding protein 3target
DB00523AlitretinoinPregnancy-specific beta-1-glycoprotein 5target
DB00523AlitretinoinCytochrome P450 26C1target
DB00755TretinoinRetinoic acid receptor gammatarget
DB00755TretinoinRetinoic acid receptor RXR-betatarget
DB00755TretinoinRetinal dehydrogenase 1target
DB00755TretinoinRetinoic acid-induced protein 3target
DB00755TretinoinRetinoic acid receptor RXR-gammatarget
DB00755TretinoinNuclear receptor subfamily 0 group B member 1target
DB00755TretinoinRetinal dehydrogenase 2target
DB00755TretinoinRetinoic acid receptor responder protein 1target
DB00755TretinoinCytochrome P450 2C8enzyme
DB00755TretinoinCellular retinoic acid-binding protein 1transporter
DB00755TretinoinCellular retinoic acid-binding protein 2transporter
DB00755TretinoinCytochrome P450 2B6enzyme
DB00755TretinoinCytochrome P450 3A4enzyme
DB00755TretinoinCytochrome P450 3A5enzyme
DB00755TretinoinCytochrome P450 2A6enzyme
DB00755TretinoinCytochrome P450 3A7enzyme
DB00755TretinoinCytochrome P450 2C18enzyme
DB00755TretinoinCytochrome P450 2C9enzyme
DB00755TretinoinCytochrome P450 4A11enzyme
DB00755TretinoinCytochrome P450 1A1enzyme
DB00755TretinoinRetinoic acid receptor alphatarget
DB00755TretinoinRetinoic acid receptor betatarget
DB00755TretinoinLipocalin-1target
DB00755TretinoinOdorant-binding protein 2atarget
DB00755TretinoinRetinol-binding protein 4target
DB00755TretinoinSerum albumincarrier
DB00755Tretinoin[Pyruvate dehydrogenase [lipoamide]] kinase isozyme 4, mitochondrialtarget
DB00755TretinoinRetinoic acid receptor RXR-alphatarget
DB00755TretinoinCytochrome P450 26A1target
DB00755TretinoinCytochrome P450 26B1target
DB00755TretinoinCytochrome P450 26C1target
DB00755TretinoinHematopoietic prostaglandin D synthasetarget
DB06755Beta caroteneBeta,beta-carotene 15,15'-dioxygenaseenzyme
DB06755Beta caroteneFree radicalstarget
DB06755Beta caroteneVery low-density lipoprotein receptorcarrier
DB06755Beta caroteneRetinol-binding protein 1carrier
DB06755Beta caroteneRetinol-binding protein 2carrier
DB06755Beta caroteneRetinol-binding protein 3carrier
DB06755Beta caroteneRetinol-binding protein 4carrier
DB06755Beta caroteneRetinol-binding protein 5carrier
DB06410DoxercalciferolSterol 26-hydroxylase, mitochondrialenzyme
DB06410DoxercalciferolVitamin D3 receptortarget
DB00910ParicalcitolVitamin D3 receptortarget
DB00910Paricalcitol1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrialenzyme
DB00910ParicalcitolCytochrome P450 3A4enzyme
DB00910ParicalcitolUDP-glucuronosyltransferase 1-4enzyme
DB04258SeocalcitolVitamin D3 receptortarget
DB04796InecalcitolVitamin D3 receptortarget
DB04891BecocalcidiolMediator of RNA polymerase II transcription subunit 1target
DB04891BecocalcidiolVitamin D3 receptortarget
DB05295EldecalcitolVitamin D3 receptortarget
DB06194ElocalcitolVitamin D3 receptortarget
DB00146Calcifediol25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrialenzyme
DB00146CalcifediolVitamin D3 receptortarget
DB00146Calcifediol1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrialenzyme
DB00153ErgocalciferolVitamin D3 receptortarget
DB00153Ergocalciferol1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrialenzyme
DB00153Ergocalciferol25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrialenzyme
DB00153ErgocalciferolSterol 26-hydroxylase, mitochondrialenzyme
DB00153ErgocalciferolVitamin D 25-hydroxylaseenzyme
DB00153ErgocalciferolVitamin D-binding proteincarrier
DB00153ErgocalciferolVoltage-dependent calcium channeltarget
DB00153ErgocalciferolRibulose-phosphate 3-epimeraseenzyme
DB00153ErgocalciferolCholesterol side-chain cleavage enzyme, mitochondrialenzyme
DB01070DihydrotachysterolVitamin D3 receptortarget
DB02300CalcipotriolVitamin D3 receptortarget
DB02300CalcipotriolMyeloperoxidaseenzyme
DB02300Calcipotriol1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrialenzyme
DB11094Vitamin DVitamin D3 receptortarget
DB11094Vitamin DVitamin D-binding proteintarget
DB11094Vitamin DVitamin D 25-hydroxylaseenzyme
DB11094Vitamin D25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrialenzyme
DB11094Vitamin DCytochrome P450 3A4enzyme
DB00169CholecalciferolVitamin D-binding proteincarrier
DB00169CholecalciferolCholesterol side-chain cleavage enzyme, mitochondrialenzyme
DB00169CholecalciferolVitamin D 25-hydroxylaseenzyme
DB00169CholecalciferolSterol 26-hydroxylase, mitochondrialenzyme
DB00169CholecalciferolCytochrome P450 2J2enzyme
DB00169CholecalciferolCytochrome P450 3A4enzyme
DB00169CholecalciferolVitamin D3 receptortarget
DB00169CholecalciferolCytochrome P450 1A1enzyme
DB00169CholecalciferolCytochrome P450 2C8enzyme
DB01436AlfacalcidolVitamin D-binding proteincarrier
DB01436AlfacalcidolVitamin D3 receptortarget
DB01436Alfacalcidol25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrialtarget
DB01436AlfacalcidolRetinoic acid receptor RXR-alphatarget