Name
Chromans
Accession Number
DBCAT002799
Description

Benzopyrans saturated in the 2 and 3 positions.

Drugs
DrugDrug Description
EpigallocatechinNot Available
CrofelemerAn antidiarrheal agent used for the symptomatic relief of drug-induced non-infectious diarrhea in adult patients with HIV/AIDS receiving antiretroviral therapy.
EpicatechinEpicatechin has been used in trials studying the treatment of Pre-diabetes.
Epigallocatechin gallateEpigallocatechin gallate has been investigated for the treatment of Hypertension and Diabetic Nephropathy.
CianidanolAn antioxidant flavonoid, occurring especially in woody plants as both (+)-catechin and (-)-epicatechin (cis) forms.
TroglitazoneFor the treatment of Type II diabetes mellitus. It is used alone or in combination with a sulfonylurea, metformin, or insulin as an adjunct to diet and exercise.
Drugs & Drug Targets
DrugTargetType
CrofelemerCystic fibrosis transmembrane conductance regulatortarget
CrofelemerAnoctamin-1target
Epigallocatechin gallateAryl hydrocarbon receptortarget
Epigallocatechin gallateDNA (cytosine-5)-methyltransferase 1target
Epigallocatechin gallateDihydrofolate reductase, mitochondrialtarget
TroglitazonePeroxisome proliferator-activated receptor gammatarget
TroglitazoneLong-chain-fatty-acid--CoA ligase 4target
TroglitazonePlasminogen activator inhibitor 1target
TroglitazoneEquilibrative nucleoside transporter 1target
TroglitazoneCytochrome P450 3A4enzyme
TroglitazoneCytochrome P450 2C19enzyme
TroglitazoneUDP-glucuronosyltransferase 1-1enzyme
TroglitazoneCytochrome P450 2C8enzyme
TroglitazoneBile salt export pumptransporter
TroglitazoneSolute carrier organic anion transporter family member 1B1transporter
TroglitazoneEstrogen-related receptor gammatarget
TroglitazoneSteroid hormone receptor ERR1target
TroglitazoneCytochrome P450 19A1enzyme
TroglitazoneCytochrome P450 1A1enzyme
TroglitazoneCytochrome P450 2B6enzyme
TroglitazoneCytochrome P450 2C9enzyme
TroglitazoneCytochrome P450 3A5enzyme
TroglitazoneCytochrome P450 3A7enzyme
TroglitazoneUDP-glucuronosyltransferase 1-3enzyme
TroglitazoneUDP-glucuronosyltransferase 1-4enzyme
TroglitazoneUDP-glucuronosyltransferase 1-6enzyme
TroglitazoneUDP-glucuronosyltransferase 1-7enzyme
TroglitazoneUDP-glucuronosyltransferase 1-8enzyme
TroglitazoneUDP-glucuronosyltransferase 1-9enzyme
TroglitazoneUDP-glucuronosyltransferase 1-10enzyme
TroglitazoneUDP-glucuronosyltransferase 2B7enzyme
TroglitazoneUDP-glucuronosyltransferase 2B15enzyme
TroglitazonePeroxisome proliferator-activated receptor deltatarget
TroglitazonePeroxisome proliferator-activated receptor alphatarget
TroglitazoneGlutathione S-transferase Ptarget