Sulfatases
- Name
- Sulfatases
- Accession Number
- DBCAT002901
- Description
A group of carbon-oxygen lyases. These enzymes catalyze the breakage of a carbon-oxygen bond in polysaccharides leading to an unsaturated product and the elimination of an alcohol. EC 4.2.2.
- Drugs
Drug Drug Description Idursulfase A purified lysosomal enzyme used as a replacement therapy for Hunter syndrome in pediatric and adult patients. Galsulfase A recombinant human enzyme used as replacement enzyme therapy for the treatment of of adults and children with Mucopolysaccharidosis VI, a rare genetic disorder caused by a deficiency of a lysosomal enzyme. Elosulfase alfa A lysosomal glycosaminoglycan (GAG)-specific enzyme indicated as an enzyme replacement therapy for Mucopolysaccharidosis type IV A. - Drugs & Drug Targets
Drug Target Type Idursulfase Perilipin-3 target Idursulfase Dermatan sulfate target Idursulfase Heparan sulfate target Galsulfase Perilipin-3 target Galsulfase Dermatan sulfate target