Immunoglobulin Variable Region

Name
Immunoglobulin Variable Region
Accession Number
DBCAT002927
Description

The paired immunoglobulin fragments composed of the variable domains of the heavy and light chains.

Drugs
DrugDrug Description
PexelizumabFor the treatment of inflammation during cardiac surgery.
CaplacizumabA von Willebrand factor (vWF)-directed antibody fragment used to treat acquired thrombotic thrombocytopenic purpura (aTTP).
VobarilizumabVobarilizumab is under investigation in clinical trial NCT02101073 (ALX-0061 Phase I Bioavailability Study in Healthy Volunteers).
GancotamabGancotamab is under investigation in clinical trial NCT02213744 (MM-302 Plus Trastuzumab vs. Chemotherapy of Physician's Choice Plus Trastuzumab in HER2-Positive Locally Advanced/Metastatic Breast Cancer Patients).
Drugs & Drug Targets
DrugTargetType
Caplacizumabvon Willebrand factortarget