Immunoglobulin Variable Region
- Name
- Immunoglobulin Variable Region
- Accession Number
- DBCAT002927
- Description
The paired immunoglobulin fragments composed of the variable domains of the heavy and light chains.
- Drugs
Drug Drug Description Caplacizumab A von Willebrand factor (vWF)-directed antibody fragment used to treat acquired thrombotic thrombocytopenic purpura (aTTP). Pexelizumab For the treatment of inflammation during cardiac surgery. Gancotamab Gancotamab is under investigation in clinical trial NCT02213744 (MM-302 Plus Trastuzumab vs. Chemotherapy of Physician's Choice Plus Trastuzumab in HER2-Positive Locally Advanced/Metastatic Breast Cancer Patients). Vobarilizumab Vobarilizumab is under investigation in clinical trial NCT02101073 (ALX-0061 Phase I Bioavailability Study in Healthy Volunteers). Gontivimab Gontivimab is under investigation in clinical trial NCT03468829 (Efficacy and Safety of ALX-0171 in Adult Hematopoietic Stem Cell Transplant (HSCT) Recipients Who Present With Respiratory Syncytial Virus (RSV) Infection). - Drugs & Drug Targets
Drug Target Type Caplacizumab von Willebrand factor target