Immunoglobulin Variable Region
- Immunoglobulin Variable Region
- Accession Number
The paired immunoglobulin fragments composed of the variable domains of the heavy and light chains.
Drug Drug Description Pexelizumab For the treatment of inflammation during cardiac surgery. Caplacizumab A von Willebrand factor (vWF)-directed antibody fragment used to treat acquired thrombotic thrombocytopenic purpura (aTTP). Vobarilizumab Vobarilizumab is under investigation in clinical trial NCT02101073 (ALX-0061 Phase I Bioavailability Study in Healthy Volunteers). Gancotamab Gancotamab is under investigation in clinical trial NCT02213744 (MM-302 Plus Trastuzumab vs. Chemotherapy of Physician's Choice Plus Trastuzumab in HER2-Positive Locally Advanced/Metastatic Breast Cancer Patients).
- Drugs & Drug Targets
Drug Target Type Caplacizumab von Willebrand factor target