Mollusk Venoms

Venoms from mollusks, including CONUS and OCTOPUS species. The venoms contain proteins, enzymes, choline derivatives, slow-reacting substances, and several characterized polypeptide toxins that affect the nervous system. Mollusk venoms include cephalotoxin, venerupin, maculotoxin, surugatoxin, conotoxins, and murexine.
DrugDrug NameDrug Description
DB06283ZiconotideAn N-type calcium channel antagonist used to manage patients with severe chronic pain who cannot tolerate, or who have not responded adequately to other treatments such as intrathecal morphine and systemic analgesics.
DB05724alpha-Conotoxin VC 1.1Investigated for use/treatment in pain (acute or chronic).
DrugDrug NameTargetType
DB06283ZiconotideCytochrome P450 3A4enzyme