Mollusk Venoms
- Name
- Mollusk Venoms
- Accession Number
- DBCAT002964
- Description
Venoms from mollusks, including CONUS and OCTOPUS species. The venoms contain proteins, enzymes, choline derivatives, slow-reacting substances, and several characterized polypeptide toxins that affect the nervous system. Mollusk venoms include cephalotoxin, venerupin, maculotoxin, surugatoxin, conotoxins, and murexine.
- Drugs
Drug Drug Description Ziconotide An N-type calcium channel antagonist used to manage patients with severe chronic pain who cannot tolerate, or who have not responded adequately to other treatments such as intrathecal morphine and systemic analgesics. alpha-Conotoxin VC 1.1 Investigated for use/treatment in pain (acute or chronic). Neosaxitoxin Neosaxitoxin is under investigation in clinical trial NCT01786655 (Safety Study of Long-Acting Local Anesthetic). - Drugs & Drug Targets
Drug Target Type Ziconotide Voltage-dependent N-type calcium channel subunit alpha-1B target Ziconotide Voltage-dependent P/Q-type calcium channel subunit alpha-1A target