Guanine Nucleotides

Name
Guanine Nucleotides
Accession Number
DBCAT003013
Description

Complex compounds of high molecular weight occurring in living cells. These are basically of two types, ribonucleic (RNA) and deoxyribonucleic (DNA) acids, both of which consist of nucleotides (nucleoside phosphates linked together by phosphate bridges).

Drugs
DrugDrug Description
Guanosine 3'-monophosphateNot Available
Cyclic GMPCyclic guanosine monophosphate (Cyclic GMP) is a guanine nucleotide containing one phosphate group which is esterified to the sugar moiety in both the 3'- and 5'-positions. It is a cellular...
Guanosine tetraphosphateGuanosine tetraphosphate is a guanine nucleotide containing four phosphate groups. Two phosphate groups are esterified to the sugar moiety in the 5' position and the other two in the 2'...
TriazavirinAn antiviral used to treat several strains of influenza.
5'-Guanosine-Diphosphate-MonothiophosphateGuanosine 5'-(trihydrogen diphosphate), monoanhydride with phosphorothioic acid. A stable GTP analog which enjoys a variety of physiological actions such as stimulation of guanine nucleotide-binding proteins, phosphoinositide hydrolysis, cyclic AMP accumulation,...
Guanosine-2'-monophosphateNot Available
8-oxo-dGMPNot Available
Phosphoaminophosphonic acid guanylate esterA non-hydrolyzable analog of GTP, in which the oxygen atom bridging the beta to the gamma phosphate is replaced by a nitrogen atom. It binds tightly to G-protein in the...
7-methyl-5'-guanylic acidNot Available
5'-GuanylylmethylenebisphosphonateNot Available
BMS-986094INX-08189 has been used in trials studying the treatment of Hepatitis C, HCV (Genotype 1), and Hepatitis C Virus.
AT-527Not Available
Drugs & Drug Targets
DrugTargetType
Guanosine 3'-monophosphateRibonucleasetarget
Guanosine 3'-monophosphateBifunctional protein PyrRtarget
Cyclic GMPcGMP-dependent 3',5'-cyclic phosphodiesterasetarget
Cyclic GMPPotassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2target
Cyclic GMPcAMP-dependent protein kinase type I-alpha regulatory subunittarget
Cyclic GMPSolute carrier family 22 member 6transporter
Guanosine tetraphosphateXanthine phosphoribosyltransferasetarget
Guanosine tetraphosphateGTPase ObgEtarget
5'-Guanosine-Diphosphate-MonothiophosphateADP-ribosylation factor 6target
5'-Guanosine-Diphosphate-MonothiophosphateProtein-glutamine gamma-glutamyltransferase Etarget
5'-Guanosine-Diphosphate-MonothiophosphateCell division protein FtsZtarget
5'-Guanosine-Diphosphate-MonothiophosphateRas-related protein Rab-11Atarget
Guanosine-2'-monophosphateGuanyl-specific ribonuclease Satarget
8-oxo-dGMP8-oxo-dGTP diphosphatasetarget
Phosphoaminophosphonic acid guanylate esterRas-related protein Rab-8Btarget
7-methyl-5'-guanylic acidm7GpppX diphosphatasetarget
5'-GuanylylmethylenebisphosphonatePhosphoenolpyruvate carboxykinase, cytosolic [GTP]target