Cytochrome P-450 CYP2B6 Inducers (weak)

Name
Cytochrome P-450 CYP2B6 Inducers (weak)
Accession Number
DBCAT003034
Description
Not Available
Drugs
DrugDrug Description
IsavuconazoleIndicated for patients 18 years of age and older for the treatment of invasive aspergillosis [FDA Label]. Indicated for patients 18 years of age and older for the treatment of...
RifabutinAn antibiotic used to treat mycobacterium avium complex disease in patients with HIV.
EsketamineA NMDA receptor antagonist used for treatment-resistant depression.
PerampanelA non-competitive AMPA glutamate receptor antagonist used to treat partial-onset seizures with or without secondarily generalized seizures, and as adjunctive treatment of primary generalized tonic-clonic seizures in patients with epilepsy.
ArtemetherAn antimalarial agent used in combination with lumefantrine for the treatment of acute uncomplicated malaria caused by Plasmodium falciparum.
RitonavirAn HIV protease inhibitor used in combination with other antivirals in the treatment of HIV infection.
Drugs & Drug Targets
DrugTargetType
IsavuconazoleCytochrome P450 3A4enzyme
IsavuconazoleCytochrome P450 3A5enzyme
IsavuconazoleCytochrome P450 2C8enzyme
IsavuconazoleCytochrome P450 2C9enzyme
IsavuconazoleCytochrome P450 2C19enzyme
IsavuconazoleCytochrome P450 2D6enzyme
IsavuconazoleCytochrome P450 2B6enzyme
IsavuconazoleUDP-glucuronosyltransferase 1-9enzyme
IsavuconazoleUDP-glucuronosyltransferase 1-8enzyme
IsavuconazoleP-glycoprotein 1transporter
IsavuconazoleATP-binding cassette sub-family G member 2transporter
IsavuconazoleSolute carrier family 22 member 2transporter
IsavuconazoleLanosterol 14-alpha demethylasetarget
IsavuconazolePotassium voltage-gated channel subfamily H member 2target
IsavuconazoleVoltage-dependent L-type calcium channel subunit alpha-1Ctarget
IsavuconazoleG protein-activated inward rectifier potassium channel 2target
IsavuconazoleG protein-activated inward rectifier potassium channel 3target
IsavuconazoleATP-sensitive inward rectifier potassium channel 11target
IsavuconazolePotassium voltage-gated channel subfamily A member 5target
IsavuconazolePotassium voltage-gated channel subfamily D member 3target
IsavuconazolePotassium voltage-gated channel subfamily KQT member 1target
IsavuconazoleSodium channel protein type 5 subunit alphatarget
RifabutinDNA-directed RNA polymerase subunit alphatarget
RifabutinHeat shock protein HSP 90-alphatarget
RifabutinEndoplasmintarget
RifabutinCytochrome P450 3A4enzyme
RifabutinDNA-directed RNA polymerase subunit betatarget
RifabutinDNA-directed RNA polymerase subunit beta'target
RifabutinCytochrome P450 2C19enzyme
RifabutinCytochrome P450 2B6enzyme
RifabutinCytochrome P450 2C8enzyme
RifabutinCytochrome P450 2C9enzyme
RifabutinP-glycoprotein 1transporter
EsketamineNMDA receptortarget
EsketamineCytochrome P450 2B6enzyme
EsketamineCytochrome P450 3A4enzyme
EsketamineCytochrome P450 2C19enzyme
EsketamineCytochrome P450 2C9enzyme
EsketamineGlutamate receptor ionotropic, NMDA 2Btarget
EsketamineElongation factor 2target
EsketamineBrain-derived neurotrophic factortarget
EsketamineBDNF/NT-3 growth factors receptortarget
PerampanelGlutamate receptor 1target
PerampanelCytochrome P450 3A4enzyme
PerampanelCytochrome P450 3A5enzyme
PerampanelCytochrome P450 1A2enzyme
PerampanelCytochrome P450 2B6enzyme
ArtemetherCytochrome P450 3A4enzyme
ArtemetherCytochrome P450 3A5enzyme
ArtemetherCytochrome P450 2B6enzyme
ArtemetherCytochrome P450 2C9enzyme
ArtemetherCytochrome P450 2C19enzyme
RitonavirHuman immunodeficiency virus type 1 proteasetarget
RitonavirCytochrome P450 2D6enzyme
RitonavirCytochrome P450 2C9enzyme
RitonavirCytochrome P450 2C19enzyme
RitonavirCytochrome P450 2B6enzyme
RitonavirCytochrome P450 2C8enzyme
RitonavirP-glycoprotein 1transporter
RitonavirMultidrug resistance-associated protein 1transporter
RitonavirCanalicular multispecific organic anion transporter 1transporter
RitonavirSolute carrier organic anion transporter family member 1A2transporter
RitonavirATP-binding cassette sub-family G member 2transporter
RitonavirSolute carrier organic anion transporter family member 1B1transporter
RitonavirCytochrome P450 1A2enzyme
RitonavirNuclear receptor subfamily 1 group I member 2target
RitonavirSerum albumincarrier
RitonavirCytochrome P450 3A4enzyme
RitonavirCytochrome P450 3A5enzyme
RitonavirCytochrome P450 3A7enzyme
RitonavirUDP-glucuronosyltransferases (UGTs)enzyme
RitonavirSolute carrier organic anion transporter family member 2B1transporter
RitonavirBile salt export pumptransporter
RitonavirAlpha-1-acid glycoprotein 1carrier
RitonavirSolute carrier organic anion transporter family member 1B3transporter