Crown Compounds

Macrocyclic compounds analogous to CROWN ETHERS but which lack any OXYGEN atoms.
DrugDrug NameDrug Description
DB11737IcotinibIcotinib hydrochloride is a novel epidermal growth factor receptor (EGFR)–tyrosine kinase inhibitor, exhibits encouraging efficacy and tolerability in patients with advanced non-small-cell lung cancer (NSCLC) who failed previous chemotherapy.