Cytoprotective Agent

Name
Cytoprotective Agent
Accession Number
DBCAT003319
Description

Not Available

Drugs
DrugDrug Description
BleomycinA chemotherapy agent used to treat various malignancies, including head and neck malignancy, lymphoma, and testicular tumors, among others.
DexrazoxaneA cytoprotective drug used to prevent and improve cardiomyopathy associated with doxorubicin treatment for metastatic breast cancer.
AmifostineA cytoprotective adjuvant used for reduction in the cumulative renal toxicity in patients with ovarian cancer and moderate to severe xerostomia in patients undergoing post-operative radiation treatment for head and neck cancer.
Coenzyme MA uroprotective agent used for the reduction and prophylaxis of oxazaphosphorine-induced toxicity in the urinary tract.
Dimethyl fumarateA medication used to treat patients with the relapsing-remitting form of multiple sclerosis.
Drugs & Drug Targets
DrugTargetType
BleomycinDNA ligase 3target
BleomycinDNA ligase 1target
BleomycinDNAtarget
BleomycinBleomycin hydrolaseenzyme
DexrazoxaneDNA topoisomerase 2-alphatarget
DexrazoxaneDNA topoisomerase 2-betatarget
AmifostineAlkaline phosphatase, germ cell typetarget
AmifostineAlkaline phosphatase, tissue-nonspecific isozymeenzyme
Dimethyl fumarateKelch-like ECH-associated protein 1target
Dimethyl fumarateTranscription factor p65target