Tubulin Inhibiting Agent

Name
Tubulin Inhibiting Agent
Accession Number
DBCAT003343
Description

Not Available

Drugs
DrugDrug Description
GriseofulvinAn antifungal agent used to treat a variety of superficial tinea infections and fungal infections of the fingernails and toes.
ColchiceineColchiceine is one of several metabolites of the anti-gout medication colchicine.
Belantamab mafodotinAn anti B-cell maturation antigen antibody conjugated to a microtubule inhibitor to treat relapsed or refractory multiple myeloma.
TirbanibulinA tyrosine kinase and tubulin inhibitor used to treat actinic keratosis on the face or scalp.
Drugs & Drug Targets
DrugTargetType
GriseofulvinKeratin, type I cytoskeletal 12target
GriseofulvinCytochrome P450 1A2enzyme
GriseofulvinCytochrome P450 3A4enzyme
GriseofulvinTubulin beta chaintarget
ColchiceineTubulin beta chaintarget
ColchiceineTubulin alpha-1A chaintarget
ColchiceineSerum albumincarrier
Belantamab mafodotinSolute carrier organic anion transporter family member 1B1transporter
Belantamab mafodotinSolute carrier organic anion transporter family member 1B3transporter
Belantamab mafodotinMultidrug resistance-associated protein 1transporter
Belantamab mafodotinCanalicular multispecific organic anion transporter 1transporter
Belantamab mafodotinCanalicular multispecific organic anion transporter 2transporter
Belantamab mafodotinBile salt export pumptransporter
Belantamab mafodotinP-glycoprotein 1transporter
Belantamab mafodotinTumor necrosis factor receptor superfamily member 17target
TirbanibulinProto-oncogene tyrosine-protein kinase Srctarget
TirbanibulinTubulin beta chaintarget
TirbanibulinCytochrome P450 3A4enzyme
TirbanibulinCytochrome P450 2C8enzyme
TirbanibulinCytochrome P450 1A2enzyme
TirbanibulinCytochrome P450 2B6enzyme
TirbanibulinCytochrome P450 2C9enzyme
TirbanibulinCytochrome P450 2C19enzyme
TirbanibulinCytochrome P450 2D6enzyme
TirbanibulinMultidrug and toxin extrusion protein 1transporter
TirbanibulinMultidrug and toxin extrusion protein 2transporter
TirbanibulinSolute carrier organic anion transporter family member 1B1transporter
TirbanibulinSolute carrier organic anion transporter family member 1B3transporter
TirbanibulinSolute carrier family 22 member 1transporter
TirbanibulinSolute carrier family 22 member 2transporter