Other Miscellaneous Therapeutic Agents

Name
Other Miscellaneous Therapeutic Agents
Accession Number
DBCAT003610
Description
Not Available
Drugs
DrugDrug Description
Botulinum Toxin Type BA purified form of botulinum toxin type B used to block acetylcholine release in the treatment of cervical dystonia and sialorrhea.
Botulinum toxin type AA purified form of botulinum toxin type A used to block acetylcholine release in the treatment of chronic sialorrhea, muscle spasticity, and dystonia, as well as in cosmetic applications.
NitisinoneA hydroxyphenylpyruvate dioxygenase inhibitor used as an adjunct to dietary restrictions for the treatment of hereditary tyrosinemia type 1 (HT-1), which causes intolerance to tyrosine containing foods.
SapropterinA cofactor used as an adjunct to phenylalanine restriction in the treatment of phenylketonuria (PKU).
CysteamineA cystine depleting agent used to treat nephrotic cystinosis.
CinacalcetA calcium sensing receptor agonist used to treat secondary hyperparathyroidism in chronic kidney disease and hypercalcemia in parathyroid carcinoma.
YohimbineAn alpha-2-adrenergic blocker and sympatholytic found in supplements used to.
Deoxycholic acidA cytolytic agent injected subcutaneously to improve the appearance submental fat.
Cyproterone acetateA steroid used in combination with ethinyl estradiol to treat women with severe acne and symptoms of androgenization. Also used alone at much higher doses for palliative treatment of patients with prostate cancer
MigalastatAn alpha-galactosidase A chaperone used for the treatment of Fabry disease in patients with an amenable galactosidase alpha gene (GLA) variant.
DalfampridineA potassium channel blocker used for the improvement of motor function in patients with multiple sclerosis (MS).
Glycine betaineA methyl group donor used for the treatment of homocystinuria to decrease elevated homocysteine blood levels.
LanreotideA somatostatin analog used for the treatment of unresectable, well- or moderately-differentiated, locally advanced or metastatic gastroenteropancreatic neuroendocrine tumors and acromegaly.
EliglustatA glucosylceramide synthase used to treat type 1 Gaucher disease in patients who are CYP2D6 extensive, intermediate, or poor metabolizers, based on the FDA-approved test.
CobicistatA CYP3A inhibitor used to increase the systemic exposure of atazanavir or darunavir in combination with other antiretroviral agents in the treatment of HIV-1 infection.
OxygenAn essential element for human survival used in clinical conditions in which there is a lack of oxygen, such as, but not limited to, anoxia, hypoxia or dyspnea.
WaterA naturally-occurring element used as an ingredient and vehicle in various pharmaceutical preparations of water.
NitrogenA cryogenic agent used to treat various benign and malignant skin lesions.
Sodium chlorideAn ingredient found in a variety of nutritional products as a source of electrolytes and water.
HeliumA gas used for medical conditions where there is a need for increased oxygen intake, such as upper airway obstruction in asthma and COPD.
Carbon dioxideA naturally-occurring gas used as a insufflation gas during minimally invasive surgeries to enlarge and stabilize body cavities to provide better visibility of the surgical area.
Medical airA mixture of gases that is primarily composed of nitrogen and oxygen used for respiratory support in a variety of conditions.
NusinersenA medication used to treat spinal muscular atrophy.
PatisiranA transthyretin-directed small interfering RNA used to treat polyneuropathy of hereditary transthyretin-mediated amyloidosis.
MiglustatA glucosylceramide synthase inhibitor used for the management of mild to moderate type I Gaucher disease for patients who are not candidates for whole enzyme replacement.
Drugs & Drug Targets
DrugTargetType
Botulinum Toxin Type BVesicle-associated membrane protein 1target
Botulinum Toxin Type BVesicle-associated membrane protein 2target
Botulinum Toxin Type BSynaptotagmin-2target
Botulinum toxin type ASynaptosomal-associated protein 25target
Botulinum toxin type ARho-related GTP-binding protein RhoBtarget
Nitisinone4-hydroxyphenylpyruvate dioxygenasetarget
SapropterinPhenylalanine-4-hydroxylasetarget
SapropterinNitric oxide synthase, endothelialtarget
SapropterinTyrosine 3-monooxygenasetarget
SapropterinTryptophan 5-hydroxylase 1target
SapropterinProstaglandin G/H synthase 2enzyme
CysteamineSomatostatintarget
CysteamineNeuropeptide Y receptor type 2target
CysteamineCystinetarget
CysteamineMyeloperoxidaseenzyme
CinacalcetExtracellular calcium-sensing receptortarget
CinacalcetCytochrome P450 3A4enzyme
CinacalcetCytochrome P450 2D6enzyme
CinacalcetCytochrome P450 1A2enzyme
YohimbineAlpha-2A adrenergic receptortarget
YohimbineAlpha-2B adrenergic receptortarget
YohimbineAlpha-2C adrenergic receptortarget
Yohimbine5-hydroxytryptamine receptor 1Atarget
Yohimbine5-hydroxytryptamine receptor 1Btarget
Yohimbine5-hydroxytryptamine receptor 1Dtarget
YohimbineDopamine D2 receptortarget
YohimbineDopamine D3 receptortarget
Yohimbine5-hydroxytryptamine receptor 2Atarget
Yohimbine5-hydroxytryptamine receptor 2Ctarget
YohimbineCytochrome P450 2D6enzyme
YohimbineCytochrome P450 3A4enzyme
YohimbineATP-sensitive potassium channeltarget
Yohimbine5-hydroxytryptamine receptor 2Btarget
Deoxycholic acidBile salt export pumptransporter
Deoxycholic acidSolute carrier organic anion transporter family member 1A2transporter
Deoxycholic acidIleal sodium/bile acid cotransportertransporter
Deoxycholic acidSodium/bile acid cotransportertransporter
Deoxycholic acidSteroid Delta-isomerasetarget
Deoxycholic acidPpcAtarget
Deoxycholic acidElongation factor Tu GTP-binding domain-containing protein 1target
Deoxycholic acidCholoylglycine hydrolasetarget
Deoxycholic acidLactaldehyde dehydrogenasetarget
Deoxycholic acidAcriflavine resistance protein Btarget
Deoxycholic acidCytochrome c oxidase subunit 1target
Deoxycholic acidCytochrome c oxidase subunit 2target
Deoxycholic acidBile acid receptortarget
Deoxycholic acidGlutathione S-transferase Ptarget
Deoxycholic acidG-protein coupled bile acid receptor 1target
Cyproterone acetateAndrogen receptortarget
Cyproterone acetateProstate-specific antigentarget
Cyproterone acetateCytochrome P450 3A4enzyme
Cyproterone acetateCytochrome P450 19A1enzyme
MigalastatAlpha-galactosidase Atarget
MigalastatUDP-glucuronosyltransferase 1-1enzyme
DalfampridineCytochrome P450 2E1enzyme
DalfampridinePotassium voltage-gated channel subfamily D member 2target
DalfampridinePotassium voltage-gated channel subfamily D member 3target
DalfampridinePotassium voltage-gated channel subfamily A member 1target
DalfampridinePotassium voltage-gated channel subfamily A member 4target
DalfampridinePotassium voltage-gated channel subfamily A member 2target
DalfampridinePotassium voltage-gated channel subfamily A member 3target
DalfampridinePotassium voltage-gated channel subfamily A member 5target
DalfampridinePotassium voltage-gated channel subfamily A member 6target
DalfampridinePotassium voltage-gated channel subfamily A member 7target
DalfampridinePotassium voltage-gated channel subfamily A member 10target
DalfampridinePotassium voltage-gated channel subfamily B member 1target
DalfampridinePotassium voltage-gated channel subfamily B member 2target
DalfampridinePotassium voltage-gated channel subfamily C member 1target
DalfampridinePotassium voltage-gated channel subfamily C member 2target
DalfampridinePotassium voltage-gated channel subfamily C member 3target
DalfampridinePotassium voltage-gated channel subfamily D member 1target
DalfampridineSolute carrier family 22 member 2transporter
Glycine betaineCholinesteraseenzyme
Glycine betaineProline dehydrogenase 1, mitochondrialenzyme
Glycine betaineApoptosis regulator Bcl-2target
LanreotideSomatostatin receptor type 2target
LanreotideSomatostatin receptor type 5target
LanreotideCytochrome P450 3A4enzyme
EliglustatCeramide glucosyltransferasetarget
EliglustatCytochrome P450 2D6enzyme
EliglustatCytochrome P450 3A4enzyme
EliglustatP-glycoprotein 1transporter
CobicistatCytochrome P450 2D6enzyme
CobicistatP-glycoprotein 1transporter
CobicistatATP-binding cassette sub-family G member 2transporter
CobicistatCytochrome P450 3A4enzyme
CobicistatCytochrome P450 3A5enzyme
CobicistatCytochrome P450 3A7enzyme
CobicistatCytochrome P450 3A43enzyme
CobicistatSolute carrier organic anion transporter family member 1B1transporter
CobicistatSolute carrier organic anion transporter family member 1B3transporter
OxygenNADPH oxidase 1target
OxygenCytochrome c oxidase subunit 1target
OxygenHemoglobin subunit betacarrier
OxygenHemoglobin subunit alphacarrier
NusinersenExonucleaseenzyme
NusinersenSurvival motor neuron proteintarget
PatisiranTransthyretin mRNAtarget
PatisiranSerum albumincarrier
Patisiranalpha1-acid glycoproteincarrier
MiglustatCeramide glucosyltransferasetarget