Somatotropin Agonists

All categories
Name
Somatotropin Agonists
Accession Number
DBCAT003614
Description

Not Available

Drugs
DrugDrug Description
SomatotropinA recombinant human growth hormone used as replacement therapy in various conditions of growth failure, growth hormone deficiency, and weakness in children and adults.
TesamorelinA growth hormone releasing factor (GRF) analog used to reduce excessive abdominal fat in HIV patients who have developed lipodystrophy.
MecaserminA recombinant insulin-like growth factor-1 used for the long-term treatment of growth failure in pediatric patients with primary IGF-1 deficiency or with growth hormone gene deletion due to the development of neutralizing antibodies to GH.
Drugs & Drug Targets
DrugTargetType
SomatotropinGrowth hormone receptortarget
SomatotropinProlactin receptortarget
SomatotropinCytochrome P450 1A2enzyme
SomatotropinCytochrome P450 2C19enzyme
SomatotropinP-glycoprotein 1transporter
TesamorelinGrowth hormone-releasing hormone receptortarget
MecaserminInsulin-like growth factor 1 receptortarget
MecaserminInsulin-like growth factor-binding protein 3target
MecaserminInsulin receptortarget
MecaserminCation-independent mannose-6-phosphate receptortarget
MecaserminInsulin-like growth factor-binding protein 3carrier
MecaserminInsulin-like growth factor-binding protein complex acid labile subunitcarrier
MecaserminInsulin-like growth factor-binding protein 1carrier
MecaserminInsulin-like growth factor-binding protein 2carrier
MecaserminInsulin-like growth factor-binding protein 4carrier
MecaserminInsulin-like growth factor-binding protein 5carrier
MecaserminInsulin-like growth factor-binding protein 6carrier