Vasodilating Agents

Name
Vasodilating Agents
Accession Number
DBCAT003676  (DBCAT000516)
Description

Drugs used to cause dilation of the blood vessels.

Drugs
DrugDrug Description
Nitric OxideA vasodilating agent used in the treatment of hypoxic respiratory failure in premature neonates.
NitroprussideA direct acting vasodilator used to treat hypertension, to induce controlled hypotension to reduce postoperative bleeding, and to manage acute heart failure.
SildenafilA phosphodiesterase inhibitor used for the treatment of erectile dysfunction.
MilrinoneAn inotropic vasodilator agent used to treat acute, decompensated heart failure.
IsradipineA dihydropyridine calcium channel blocker used for the treatment of hypertension.
TheophyllineA xanthine used to manage the symptoms of asthma, COPD, and other lung conditions caused by reversible airflow obstruction.
DiltiazemA calcium channel blocker used to treat hypertension and to manage chronic stable angina.
MinoxidilAn antihypertensive vasodilating agent used for resistant hypertension that is symptomatic or has caused end organ damage.
AmlodipineA calcium channel blocker used to treat hypertension and angina.
NimodipineA calcium channel blocker used to improve neurological outcomes in patients with subarachnoid hemorrhage due to a ruptured intracranial aneurysm.
NisoldipineA calcium channel blocker used as monotherapy or combined with other drugs for the treatment of hypertension.
RosiglitazoneA thiazolidinedione indicated as an adjunct to diet and exercise to maintain glycemic control in type 2 diabetes.
PropranololA non-selective beta adrenergic antagonist used to treat hypertension, angina, atrial fibrillation, myocardial infarction, migraine, essential tremor, hypertrophic subaortic stenosis, and pheochromocytoma.
NicardipineA calcium channel blocker used for the short-term treatment of hypertension and chronic stable angina.
NiacinA B vitamin used to treat hypertriglyceridemia and pellagra.
AdenosineA medication used in myocardial perfusion scintigraphy.
DyphyllineA theophylline derivative used to treat asthma, bronchospasm, and COPD.
VerapamilA non-dihydropyridine calcium channel blocker used in the treatment of angina, arrhythmia, and hypertension.
NicergolineFor the treatment of senile dementia, migraines of vascular origin, transient ischemia, platelet hyper-aggregability, and macular degeneration.
NitroglycerinA nitrate vasodilator used to treat or prevent angina, treat hypertension, control heart failure in myocardial infarction, and to induce hypotension intraoperatively.
AlprostadilA medication used to treat erectile dysfunction.
TolazolineA vasodilator used to treat pulmonary artery anomalies.
FenoldopamA dopamine D1 receptor agonist used for the short term management of hypertension.
PentoxifyllineA methylxanthine derivative used to treat intermittent claudication caused by chronic occlusive arterial disease of the limbs.
TadalafilA phosphodiesterase 5 inhibitor used to treat erectile dysfunction, benign prostatic hyperplasia, and pulmonary arterial hypertension.
VardenafilA phosphodiesterase 5 inhibitor used to treat erectile dysfunction.
Isosorbide dinitrateA vasodilator used to treat angina in coronary artery disease.
LevosimendanFor short term treatment of acutely decompensated severe chronic heart failure (CHF). Also being investigated for use/treatment in heart disease.
PhenoxybenzamineAn alpha adrenergic agonist used to treat pheochromocytoma and episodes of hypertension and sweating.
PindololA beta adrenoceptor antagonist used to treat hypertension, edema, ventricular tachycardias, and atrial fibrillation.
DipyridamoleA phosphodiesterase inhibitor used to prevent postoperative thromboembolic events.
Isosorbide mononitrateA nitrate used to prevent and treat angina and to treat angina caused by coronary artery disease.
FelodipineA calcium channel blocker used to treat hypertension.
Ergoloid mesylateA nootropic with an unknown mechanism of action indicated in individuals over sixty who manifest signs and symptoms of an idiopathic decline in mental capacity.
NitrendipineFor the treatment of mild to moderate hypertension
PerhexilineFor the management of severe angina pectoris.
IloprostA synthetic prostacyclin analog indicated to treat pulmonary arterial hypertension (PAH).
PapaverineAn alkaloid used to treat many types of smooth muscle spasms such as "vascular spasms" associated with acute myocardial infarction and angina pectoris, as well as "visceral spasms".
NifedipineA dihydropyridine calcium channel blocker indicated for the management of several subtypes of angina pectoris, and hypertension.
TrimethaphanFor the controlled reduction of blood pressure during surgery and in the treatment of hypertensive emergencies.
AmiodaroneA class III antiarrhythmic indicated for the treatment of recurrent hemodynamically unstable ventricular tachycardia and recurrent ventricular fibrillation.
DiazoxideA non diuretic benzothiadiazine indicated for the management of hypoglycemia in patients who produce an excess of insulin caused by a variety of conditions.
CarvedilolA non selective beta-adrenergic antagonist used to treat mild to severe chronic heart failure, hypertension, and left ventricular dysfunction following myocardial infarction in clinically stable patients.
CilostazolAn antiplatelet agent and vasodilator used for the symptomatic relief of intermittent claudication.
BepridilFor the treatment of hypertension, and chronic stable angina (classic effort-associated angina).
HydralazineAn antihypertensive agent used for the management of essential hypertension or severe hypertension associated with conditions requiring immediate action, heart failure, and pre-eclampsia or eclampsia .
MibefradilFor the treatment of angina and high blood pressure.
Theobrominetheobromine is used as a vasodilator, a diuretic, and heart stimulant. And similar to caffeine, it may be useful in management of fatigue and orthostatic hypotension.
AmrinoneA positive inotropic agent and phosphodiesterase inhibitor used in the management of treatment of congestive heart failure.
OxprenololA non-selective beta-adrenergic antagonist used to treat hypertension, angina pectoris, arrhythmias, and anxiety.
Amyl NitriteA fast acting vasodilator used for rapid relief of angina pectoris.
Erythrityl tetranitrateFor the prevention of angina.
ColforsinPotent activator of the adenylate cyclase system and the biosynthesis of cyclic AMP. From the plant Coleus forskohlii. Has antihypertensive, positive inotropic, platelet aggregation inhibitory, and smooth muscle relaxant activities;...
ResveratrolBeing investigated for the treatment of Herpes labialis infections (cold sores).
AcetylcholineA parasympathomimetic neurotransmitter used to induce miosis of the iris in seconds after delivery of the lens in cataract surgery, in penetrating keratoplasty, iridectomy and other anterior segment surgery where rapid miosis may be required.
N-(6-Aminohexyl)-5-Chloro-1-NaphthalenesulfonamideNot Available
PrenylaminePrenylamine was withdrawn from the Canadian, US, and UK markets in 1988 due to concerns regarding cardiac arrhythmias.
CyclandelateA vasodilator used for the treatment of various blood vessel diseases, such as claudication and arteriosclerosis.
FlunarizineA selective calcium-entry blocker used as migraine prophylaxis in patients with severe and frequent episodes who have not responded adequately to more common treatments.
CeliprololCeliprolol is indicated for the management of mild to moderate hypertension and effort-induced angina pectoris.
NebivololA beta blocking agent used to treat hypertension and aid in the management of heart failure.
EnoximoneFor the treatment of congestive heart failure.
BeraprostFor the treatment of pulmonary hypertension.
IbudilastFor the treatment of multiple sclerosis, asthma, and cerebrovascular disease.
NylidrinA vasodilator used to treat patients with peripheral vascular disorders, and elderly patients with symptoms associated with organic mental disorders.
Pentaerythritol tetranitrateUsed for the treatment of angina pectoris .
Calcitonin gene-related peptideInvestigated for use/treatment in myocardial infarction, heart disease, and asthma.
DotarizineInvestigated for use/treatment in migraine and cluster headaches.
TezosentanInvestigated for use/treatment in congestive heart failure, liver disease, and heart disease.
XylometazolineA direct acting sympathomimetic agent used for the symptomatic treatment of nasal congestion and minor inflammation due to allergies or colds.
BetahistineAn antivertigo agent used for the reduction of episodes of vertigo association with Ménière's disease.
DrotaverineUsed in the treatment of functional bowel disorders and alleviating pain in renal colic.
PinacidilPinacidil is a cyanoguanidine drug that acts by opening ATP-sensitive potassium channels, leading to peripheral vasodilatation of arterioles and decreasing peripheral vascular resistance. The above processes result in reduced blood...
IsoxsuprineA beta-adrenergic agonist used in the symptomatic treatment of cerebrovascular insufficiency, peripheral vascular disease of arteriosclerosis obliterans, thromboangiitis obliterans (Buerger's disease) and Raynaud's disease.
Inositol nicotinateA vasodilator and source of niacin found in dietary supplements.
IndenololIndenolol is a drug of the beta-adrenergic blocker class.
IfenprodilIfenprodil is a selective NMDA receptor (glutamate) antagonist.
EperisoneEperisone is an antispasmodic drug which relaxes both skeletal muscles and vascular smooth muscles, and demonstrates a variety of effects such as reduction of myotonia, improvement of circulation, and suppression...
TrimetazidineTrimetazidine is indicated for use in angina pectoris.
XanthinolA vasodilatory niacin found in diet supplements.
MoxisylyteBy the WHO, moxisylyte is indicated for the symptomatic management of sequelae of cerebral infarction or hemorrhage. The cerebral infarction is characterized by the blockage of the artery either by...
TrimazosinTrimazosin is a sympatholytic alpha blocker.
NicorandilIndicated for the prevention and treatment of chronic stable angina pectoris and reduction in the risk of acute coronary syndromes.
BenidipineBenidipine is a potent and long-lasting drug indicated for the treatment of cardiovascular diseases such as hypertension, renoparenchymal hypertension and angina pectoris.
MolsidomineThe indications for use of molsidomine include ischemic heart disease, angina, chronic heart failure, and pulmonary hypertension [L1370, L1371].
TrapidilUsed in the treatment of chronic stable angina .
ImolamineImolamine is indicated for the treatment of angina pectoris. The hydrochloride form is used as a local anesthetic.
PimobendanNot Annotated
AnisodamineAnisodamine has been investigated for the treatment of Intestinal Diseases.
BradykininBradykinin has been investigated for the basic science and treatment of Hypertension and Diabetes Type 2.
VinpocetineVinpocetine has been investigated for the treatment of Epilepsy.
SimendanSimendan is under investigation in clinical trial NCT00527059 (Renal Effects of Levosimendan in Patients Admitted With Acute Decompensated Heart Failure).
PuerarinPuerarin has been investigated for the treatment of Alcohol Abuse.
DopexamineDopexamine has been used in trials studying the diagnostic and treatment of Free Flap, Oral Cancer, Hypotension, Septic Shock, and Head and Neck Cancer.
UrapidilUrapidil has been investigated for the treatment of Hypertension During Pre-Eclampsia.
BucindololBucindolol has been investigated in Heart Failure.
CafedrineCafedrine is under investigation in clinical trial NCT01311414 (Effect of Cafedrine/Theodrenaline and Urapidil on Cerebral Oxygenation).
BamifyllineBamifylline is a selective A1 adenosine receptor antagonist.
BamethanNot Annotated
FlosequinanFlosequinan was approved in the USA and the UK for a year prior to being withdrawn from the market due to increased mortality in chronic heart failure patients, found in...
HexobendineHexobendine is a medication used to cause vasodilation, to treat several conditions including angina pectoris. It has not been approved in the United States or the United Kingdom, but has...
CarbocromenCarbocromen was marketed for use in Germany as a vasodilator, however, it has been discontinued due to the risk of arrhythmia development .
IbopamineNot Annotated
SuloctidilNot Annotated
DihydroergocristineAn ergot alkaloid used to delay progressive mental decline in conditions like Alzheimer's.
VincamineVincamine is a monoterpenoid indole alkaloid obtained from the leaves of Vinca minor with a vasodilatory property. Studies indicate that vincamine increases the regional cerebral blood flow.
DihydroergocryptineNot Annotated
OxyfedrineNot Annotated
LinsidomineNot Annotated
NicofuranoseNot Annotated
EndralazineNot Annotated
CadralazineNot Annotated
BencyclaneA vasodilator agent found to be effective in a variety of peripheral circulation disorders. It has various other potentially useful pharmacological effects. Its mechanism may involve block of calcium channels.
BuflomedilNot Annotated
NaftidrofurylNot Annotated
ButalamineNot Annotated
DilazepNot Annotated
CetiedilNot Annotated
LidoflazineNot Annotated
VinburnineNot Annotated
BufyllineNot Annotated
EtafenoneEtafenone is a vasodilator.
TreprostinilA prostacyclin vasodilator for the treatment of pulmonary arterial hypertension to relieve exercise associated symptoms and to prevent clinical deterioration after stopping epoprostenol.
BosentanA dual endothelin receptor antagonist used to treat pulmonary arterial hypertension.
EpoprostenolA vasodilator and platelet aggregation inhibitor used for the management of primary pulmonary hypertension and pulmonary hypertension in patients with heart failure.
AmbrisentanA selective type A endothelin receptor antagonist used to treat primary pulmonary arterial hypertension and pulmonary arterial hypertension based on diagnostic classifications.
RiociguatA stimulator of soluble guanylate cyclase indicated for the management of persistent or recurrent chronic thromboembolic pulmonary hypertension and pulmonary arterial hypertension.
MacitentanAn endothelin receptor antagonist used to manage pulmonary arterial hypertension to delay disease progression.
SelexipagA non prostanoid IP prostacyclin receptor agonist used to treat pulmonary arterial hypertension.
UdenafilInvestigated for use/treatment in erectile dysfunction and hypertension.
MirodenafilMirodenafil has been used in trials studying the treatment and supportive care of Kidney Diseases, Urologic Diseases, Renal Insufficiency, Erectile Dysfunction, and Male Erectile Dysfunction.
AvanafilA phosphodiesterase 5 (PDE5) inhibitor used to treat erectile dysfunction.
FostamatinibA spleen tyrosine kinase inhibitor used to treat chronic immune thrombocytopenia after attempting one other treatment.
LefradafibanFor the treatment of unstable angina.
Alferminogene tadenovecInvestigated for use/treatment in angina, coronary artery disease, and heart disease.
RanolazineAn anti-anginal drug used for the treatment of chronic angina.
Propatyl nitrateNot Annotated
Methylpropylpropanediol dinitrateNot Annotated
TenitramineNot Annotated
TrolnitrateNot Annotated
AgmatineAgmatine is being studied experimentally for several indications such as cardioprotection, diabetes, decreased kidney function, neuroprotection (stroke, severe CNS injuries, epilepsy, glaucoma, and neuropathic pain), and psychiatric conditions (depression, anxiety,...
AranidipineAranidipine has been used for many years to treat angina pectoris and hypertension.
AzelnidipineFor the treatment of hypertension.
BarnidipineIndicated for the treatment of mild to moderate essential hypertension and management of chronic stable angina.
CaroverineNot Annotated
CilnidipineCilnidipine is indicated for the management of hypertension for end-organ protection. It is reported to be useful in elderly patients and in those with diabetes and albuminuria. Cilnidipine has been...
CinnarizineFor the treatment of vertigo/meniere's disease, nausea and vomiting, motion sickness and also useful for vestibular symptoms of other origins.
ClevidipineA dihydropyridine L-type calcium channel blocker used to lower blood pressure when oral antihypertensive therapy is not feasible or not desirable.
DarodipineDarodipine is a calcium channel blocker.
EfonidipineFor the treatment of hypertension.
FendilineFendiline is a coronary vasodilator which inhibits calcium function in muscle cells in excitation-contraction coupling. It has been proposed as an antiarrhythmic and antianginal agent. Fendiline is non-selective.
Fish oilA source of essential fatty acids used as a source of calories in parenteral nutrition and as a dietary supplement.
GallopamilGallopamil has been used in trials studying the treatment of Asthma.
LacidipineIndicated for the treatment of hypertension either alone or in combination with other antihypertensive agents, including β-adrenoceptor antagonists, diuretics, and ACE-inhibitors .
LercanidipineFor the treatment of Hypertension, management of angina pectoris and Raynaud's syndrome
Magnesium sulfateA drug used to treat convulsions during pregnancy, nephritis in children, magnesium deficiency, and tetany.
ManidipineFor the treatment of hypertension.
LevomentholAn organic compound used to treat mild to moderate muscle and joint pain.
NaftopidilNaftopidil has been investigated for the treatment of Disorder of Urinary Stent.
NiguldipineNiguldipine is a calcium channel blocker drug (CCB) with a1-adrenergic antagonist properties.
NiludipineNiludipine is a calcium channel blocker.
NilvadipineFor the management of vasospastic angina, chronic stable angina and hypertension.
OtiloniumNot Annotated
PinaveriumA spasmolytic agent used for the symptomatic treatment of irritable bowel syndrome (IBS) and functional disorders of the biliary tract.
PregabalinAn anticonvulsant drug used to treat neuropathic pain conditions and fibromyalgia, and for the treatment of partial onset seizures in combination with other anticonvulsants.
SeletracetamInvestigated for use/treatment in epilepsy.
TerodilineNot Annotated
TetrahydropalmatineTetrahydropalmatine is under investigation in clinical trial NCT02118610 (Treatment of Schizophrenia With L-tetrahydropalmatine (l-THP): a Novel Dopamine Antagonist With Anti-inflammatory and Antiprotozoal Activity).
ZiconotideAn N-type calcium channel antagonist used to manage patients with severe chronic pain who cannot tolerate, or who have not responded adequately to other treatments such as intrathecal morphine and systemic analgesics.
PrazosinAn alpha-blocker that causes a decrease in total peripheral resistance and is used to treat hypertension.
KetamineA rapid-acting general anesthetic and NMDA receptor antagonist used for induction of anesthesia diagnostic and surgical procedures typically in combination with a muscle relaxant.
PhentolamineAn alpha adrenergic antagonist used to reverse soft tissue anesthesia.
FluoxetineA selective serotonin reuptake inhibitor used to treat major depressive disorder, bulimia, OCD, premenstrual dysphoric disorder, panic disorder, and bipolar I.
CitalopramA selective serotonin reuptake inhibitor (SSRI) used in the treatment of depression.
LabetalolAn alpha and beta adrenergic antagonist used to treat hypertension, angina, and sympathetic overactivity syndrome.
DexverapamilNot Annotated
DexpropranololNot Available
Nicotinyl alcoholA direct-acting peripheral vasodilator that causes flushing and may decrease blood pressure. It is used in vasospasm and threatened gangrene. [PubChem]
FasudilFasudil has been investigated in Carotid Stenosis.
IsosorbideA vasodilator used for the prevention and treatment of angina pectoris due to coronary artery disease.
NitrateNot Annotated
AnagrelideA platelet-reducing agent used to treat thrombocythemia, and its related complications, secondary to myeloproliferative neoplasms.
DoxofyllineIndicated for the treatment of chronic obstructive pulmonary disease (COPD), bronchial asthma and pulmonary disease with spastic bronchial component.
Angiotensin 1-7TXA127 has been investigated for the treatment of Miscellaneous Peripheral Blood Cell Abnormalities.
CinepazideCinepazide has been used in trials studying the treatment of Ischemic Stroke.
Atrial natriuretic peptideNot Annotated
ErythritolErythritol is a four-carbon sugar that is found in algae, fungi, and lichens. It is twice as sweet as sucrose and can be used as a coronary vasodilator.
Drugs & Drug Targets
DrugTargetType
Nitric OxideGuanylate cyclase soluble subunit alpha-2target
Nitric OxideAldehyde dehydrogenase, mitochondrialenzyme
Nitric OxideCytochrome P450 1A2enzyme
Nitric OxideCytochrome P450 2B6enzyme
Nitric OxideCytochrome P450 3A4enzyme
Nitric OxideMetallothionein-1Atarget
Nitric OxideIndoleamine 2,3-dioxygenase 1target
NitroprussideAtrial natriuretic peptide receptor 1target
NitroprussideCytochrome P450 1A1enzyme
SildenafilcGMP-specific 3',5'-cyclic phosphodiesterasetarget
SildenafilCytochrome P450 2C9enzyme
SildenafilRetinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gammatarget
SildenafilRetinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gammatarget
SildenafilCytochrome P450 3A4enzyme
SildenafilCytochrome P450 3A5enzyme
SildenafilCytochrome P450 3A7enzyme
SildenafilMultidrug resistance-associated protein 4transporter
SildenafilMultidrug resistance-associated protein 5transporter
SildenafilMultidrug resistance-associated protein 7transporter
SildenafilCytochrome P450 2C19enzyme
SildenafilCytochrome P450 2D6enzyme
SildenafilCytochrome P450 2E1enzyme
SildenafilSolute carrier organic anion transporter family member 1B1transporter
SildenafilP-glycoprotein 1transporter
MilrinonecGMP-inhibited 3',5'-cyclic phosphodiesterase Atarget
IsradipineVoltage-dependent calcium channel subunit alpha-2/delta-1target
IsradipineVoltage-dependent L-type calcium channel subunit alpha-1Ctarget
IsradipineCytochrome P450 3A4enzyme
IsradipineVoltage-dependent T-type calcium channel subunit alpha-1Htarget
IsradipineVoltage-dependent calcium channel subunit alpha-2/delta-2target
IsradipineVoltage-dependent L-type calcium channel subunit beta-2target
IsradipineVoltage-dependent L-type calcium channel subunit alpha-1Dtarget
IsradipineVoltage-dependent L-type calcium channel subunit alpha-1Starget
IsradipineBile salt export pumptransporter
TheophyllinecGMP-inhibited 3',5'-cyclic phosphodiesterase Atarget
TheophyllinecAMP-specific 3',5'-cyclic phosphodiesterase 4Btarget
TheophyllineAdenosine receptor A2btarget
TheophyllinecAMP-specific 3',5'-cyclic phosphodiesterase 4Atarget
TheophyllinecGMP-specific 3',5'-cyclic phosphodiesterasetarget
TheophyllineAdenosine receptor A1target
TheophyllineAdenosine receptor A2atarget
TheophyllineCytochrome P450 1A2enzyme
TheophyllineAdenosine deaminaseenzyme
TheophyllineCytochrome P450 2E1enzyme
TheophyllineCytochrome P450 3A4enzyme
TheophyllineSolute carrier family 22 member 7transporter
TheophyllineCytochrome P450 1A1enzyme
TheophyllineCytochrome P450 1B1enzyme
TheophyllineCytochrome P450 2D6enzyme
TheophyllineHistone deacetylase 2target
TheophyllineCopine-1target
TheophyllineMinor histocompatibility antigen H13target
TheophyllineNodal modulator 1target
TheophyllinePoly [ADP-ribose] polymerase 1target
TheophyllineProtein RIC-3target
TheophyllineTubulin monoglycylase TTLL3target
DiltiazemVoltage-dependent calcium channel gamma-1 subunittarget
DiltiazemCytochrome P450 3A4enzyme
DiltiazemCytochrome P450 2C19enzyme
DiltiazemCytochrome P450 2D6enzyme
DiltiazemCytochrome P450 3A5enzyme
DiltiazemCytochrome P450 3A7enzyme
DiltiazemP-glycoprotein 1transporter
DiltiazemCytochrome P450 2C8enzyme
DiltiazemSerum albumincarrier
DiltiazemAlpha-1-acid glycoprotein 1carrier
DiltiazemVoltage-dependent L-type calcium channel subunit alpha-1Ctarget
MinoxidilATP-sensitive inward rectifier potassium channel 1target
MinoxidilProstaglandin G/H synthase 1target
MinoxidilRenintarget
MinoxidilUDP-glucuronosyltransferase 1-1enzyme
AmlodipineCarbonic anhydrase 1target
AmlodipineCytochrome P450 3A4enzyme
AmlodipineVoltage-dependent L-type calcium channel subunit alpha-1Ctarget
AmlodipineCytochrome P450 1A1enzyme
AmlodipineCytochrome P450 2B6enzyme
AmlodipineVoltage-dependent N-type calcium channel subunit alpha-1Btarget
AmlodipineVoltage-dependent L-type calcium channel subunit beta-1target
AmlodipineVoltage-dependent calcium channel subunit alpha-2/delta-3target
AmlodipineCytochrome P450 3A5enzyme
AmlodipineP-glycoprotein 1transporter
AmlodipineCytochrome P450 2C8enzyme
AmlodipineCytochrome P450 2D6enzyme
AmlodipineSphingomyelin phosphodiesterasetarget
AmlodipineVoltage-dependent T-type calcium channel subunit alpha-1Itarget
AmlodipineVoltage-dependent N-type calcium channeltarget
NimodipineCytochrome P450 3A4enzyme
NimodipineMineralocorticoid receptortarget
NimodipineVoltage-dependent L-type calcium channel subunit alpha-1Dtarget
NimodipineVoltage-dependent L-type calcium channel subunit alpha-1Starget
NimodipineVoltage-dependent L-type calcium channel subunit alpha-1Ctarget
NimodipineVoltage-dependent L-type calcium channel subunit beta-2target
NimodipineVoltage-dependent L-type calcium channel subunit alpha-1Ftarget
NimodipineVoltage-dependent L-type calcium channel subunit beta-1target
NimodipineVoltage-dependent L-type calcium channel subunit beta-3target
NimodipineVoltage-dependent L-type calcium channel subunit beta-4target
NimodipineAryl hydrocarbon receptortarget
NisoldipineCytochrome P450 3A4enzyme
NisoldipineVoltage-dependent L-type calcium channel subunit alpha-1Dtarget
NisoldipineVoltage-dependent L-type calcium channel subunit alpha-1Starget
NisoldipineVoltage-dependent L-type calcium channel subunit alpha-1Ctarget
NisoldipineVoltage-dependent calcium channel subunit alpha-2/delta-1target
NisoldipineVoltage-dependent L-type calcium channel subunit beta-2target
NisoldipineCytochrome P450 3A5enzyme
NisoldipineCytochrome P450 3A7enzyme
NisoldipineP-glycoprotein 1transporter
RosiglitazonePeroxisome proliferator-activated receptor gammatarget
RosiglitazoneCytochrome P450 2C8enzyme
RosiglitazoneCytochrome P450 2C9enzyme
RosiglitazoneLong-chain-fatty-acid--CoA ligase 4target
RosiglitazoneSolute carrier organic anion transporter family member 1B1transporter
RosiglitazoneProstaglandin G/H synthase 1enzyme
RosiglitazoneCytochrome P450 1A2enzyme
RosiglitazoneCytochrome P450 2A6enzyme
RosiglitazoneCytochrome P450 2D6enzyme
RosiglitazoneSerum albumincarrier
RosiglitazonePeroxisome proliferator-activated receptor alphatarget
RosiglitazonePeroxisome proliferator-activated receptor deltatarget
RosiglitazoneRetinoic acid receptor RXR-alphatarget
RosiglitazoneRetinoic acid receptor RXR-betatarget
RosiglitazoneRetinoic acid receptor RXR-gammatarget
RosiglitazoneCytochrome P450 3A4enzyme
RosiglitazoneBile salt export pumptransporter
PropranololBeta-1 adrenergic receptortarget
PropranololBeta-2 adrenergic receptortarget
PropranololBeta-3 adrenergic receptortarget
Propranolol5-hydroxytryptamine receptor 1Atarget
Propranolol5-hydroxytryptamine receptor 1Btarget
PropranololCytochrome P450 1A2enzyme
PropranololCytochrome P450 2D6enzyme
PropranololAlpha-1-acid glycoprotein 1carrier
PropranololCytochrome P450 2C19enzyme
PropranololCytochrome P450 3A4enzyme
PropranololCytochrome P450 3A5enzyme
PropranololCytochrome P450 3A7enzyme
PropranololSolute carrier family 22 member 2transporter
PropranololP-glycoprotein 1transporter
PropranololCytochrome P450 1A1enzyme
PropranololAmine oxidase [flavin-containing] Aenzyme
PropranololSerum albumincarrier
NicardipineVoltage-dependent L-type calcium channel subunit alpha-1Ctarget
NicardipineCytochrome P450 3A4enzyme
NicardipineCytochrome P450 2C19enzyme
NicardipineCytochrome P450 2C8enzyme
NicardipineCytochrome P450 2D6enzyme
NicardipineCalcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1Btarget
NicardipineCalcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1Atarget
NicardipineAlpha-1A adrenergic receptortarget
NicardipineAlpha-1D adrenergic receptortarget
NicardipineAlpha-1B adrenergic receptortarget
NicardipineMuscarinic acetylcholine receptor M1target
NicardipineMuscarinic acetylcholine receptor M2target
NicardipineMuscarinic acetylcholine receptor M3target
NicardipineMuscarinic acetylcholine receptor M4target
NicardipineMuscarinic acetylcholine receptor M5target
NicardipineVoltage-dependent calcium channel subunit alpha-2/delta-1target
NicardipineVoltage-dependent L-type calcium channel subunit beta-2target
NicardipineVoltage-dependent L-type calcium channel subunit alpha-1Dtarget
NicardipineCalmodulintarget
NicardipineP-glycoprotein 1transporter
NicardipineCytochrome P450 2B6enzyme
NicardipineCytochrome P450 2E1enzyme
NicardipineCytochrome P450 3A5enzyme
NicardipineSolute carrier organic anion transporter family member 1B1transporter
NicardipineBile salt export pumptransporter
NicardipineCytochrome P450 2C9enzyme
NiacinHydroxycarboxylic acid receptor 2target
NiacinNicotinamide N-methyltransferasetarget
NiacinNicotinate-nucleotide pyrophosphorylase [carboxylating]target
NiacinHydroxycarboxylic acid receptor 3target
NiacinSolute carrier family 22 member 5transporter
NiacinSolute carrier organic anion transporter family member 2B1transporter
NiacinMonocarboxylate transporter 1transporter
NiacinCytochrome P450 2D6enzyme
NiacinSodium-coupled monocarboxylate transporter 1transporter
NiacinMonocarboxylate transporter 4transporter
NiacinThyroxine-binding globulincarrier
NiacinCytochrome P450 3A4enzyme
NiacinCytochrome P450 2E1enzyme
AdenosineAdenosine receptor A3target
AdenosineAdenosine deaminaseenzyme
AdenosineAdenosine kinaseenzyme
AdenosineAdenosine receptor A1target
AdenosineAdenosine receptor A2atarget
AdenosineAdenosine receptor A2btarget
AdenosineSolute carrier family 28 member 3transporter
DyphyllinecAMP-specific 3',5'-cyclic phosphodiesterase 4Btarget
DyphyllinecAMP-specific 3',5'-cyclic phosphodiesterase 4Atarget
DyphyllinecAMP-specific 3',5'-cyclic phosphodiesterase 4Ctarget
DyphyllinecAMP-specific 3',5'-cyclic phosphodiesterase 4Dtarget
DyphyllineAdenosine receptor A1target
DyphyllineAdenosine receptor A2atarget
VerapamilATP-sensitive inward rectifier potassium channel 11target
VerapamilVoltage-dependent T-type calcium channel subunit alpha-1Gtarget
VerapamilPotassium voltage-gated channel subfamily H member 2target
VerapamilVoltage-dependent L-type calcium channel subunit alpha-1Ctarget
VerapamilCytochrome P450 1A2enzyme
VerapamilCytochrome P450 3A5enzyme
VerapamilVoltage-dependent N-type calcium channel subunit alpha-1Btarget
VerapamilVoltage-dependent P/Q-type calcium channel subunit alpha-1Atarget
VerapamilSodium-dependent serotonin transportertarget
VerapamilCytochrome P450 3A4enzyme
VerapamilP-glycoprotein 1transporter
VerapamilSolute carrier family 22 member 1transporter
VerapamilCanalicular multispecific organic anion transporter 2transporter
VerapamilMultidrug resistance-associated protein 4transporter
VerapamilSolute carrier family 22 member 5transporter
VerapamilSolute carrier organic anion transporter family member 1A2transporter
VerapamilMultidrug resistance-associated protein 7transporter
VerapamilSolute carrier family 22 member 4transporter
VerapamilSolute carrier organic anion transporter family member 1B1transporter
VerapamilCytochrome P450 2C8enzyme
VerapamilCytochrome P450 2C9enzyme
VerapamilCytochrome P450 2B6enzyme
VerapamilCytochrome P450 2C19enzyme
VerapamilCytochrome P450 2D6enzyme
VerapamilAlpha-1A adrenergic receptortarget
VerapamilAlpha-1B adrenergic receptortarget
VerapamilAlpha-1D adrenergic receptortarget
VerapamilSerum albumincarrier
VerapamilAlpha-1-acid glycoprotein 1carrier
VerapamilCytochrome P450 2C18enzyme
VerapamilCytochrome P450 2E1enzyme
VerapamilMultidrug resistance-associated protein 1transporter
VerapamilMultidrug and toxin extrusion protein 1transporter
VerapamilMultidrug and toxin extrusion protein 2transporter
VerapamilVoltage-dependent T-type calcium channel subunit alpha-1Htarget
NicergolineAlpha-1A adrenergic receptortarget
NicergolineCytochrome P450 2D6enzyme
NitroglycerinAtrial natriuretic peptide receptor 1target
NitroglycerinAldehyde dehydrogenase, mitochondrialenzyme
AlprostadilProstaglandin E2 receptor EP2 subtypetarget
AlprostadilProstaglandin E2 receptor EP1 subtypetarget
AlprostadilMultidrug resistance-associated protein 5transporter
AlprostadilSolute carrier organic anion transporter family member 2B1transporter
AlprostadilSolute carrier organic anion transporter family member 3A1transporter
AlprostadilMultidrug resistance-associated protein 4transporter
AlprostadilSolute carrier organic anion transporter family member 2A1transporter
AlprostadilProstaglandin D2 receptor 2target
AlprostadilSolute carrier family 22 member 6transporter
TolazolineAlpha-1A adrenergic receptortarget
TolazolineAlpha-2A adrenergic receptortarget
TolazolineHistamine H1 receptortarget
TolazolineHistamine H2 receptortarget
TolazolineAlpha-2C adrenergic receptortarget
TolazolineAlpha-2B adrenergic receptortarget
FenoldopamDopamine D5 receptortarget
FenoldopamDopamine D1 receptortarget
FenoldopamAlpha-2B adrenergic receptortarget
FenoldopamAlpha-2C adrenergic receptortarget
FenoldopamAlpha-2A adrenergic receptortarget
FenoldopamAlpha-1B adrenergic receptortarget
FenoldopamAlpha-1D adrenergic receptortarget
FenoldopamAlpha-1A adrenergic receptortarget
Pentoxifylline5'-nucleotidasetarget
PentoxifyllineAdenosine receptor A1target
PentoxifyllineAdenosine receptor A2atarget
PentoxifyllineCytochrome P450 1A2enzyme
PentoxifyllinePhosphodiesterase enzymestarget
TadalafilcGMP-specific 3',5'-cyclic phosphodiesterasetarget
TadalafilCytochrome P450 3A4enzyme
TadalafilDual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11Atarget
TadalafilCytochrome P450 3A5enzyme
VardenafilcGMP-specific 3',5'-cyclic phosphodiesterasetarget
VardenafilCytochrome P450 3A4enzyme
VardenafilRetinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gammatarget
VardenafilRetinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gammatarget
VardenafilCytochrome P450 3A5enzyme
VardenafilP-glycoprotein 1transporter
Isosorbide dinitrateAtrial natriuretic peptide receptor 1target
Isosorbide dinitrateCytochrome P450 2E1enzyme
LevosimendanTroponin C, slow skeletal and cardiac musclestarget
LevosimendanATP-sensitive inward rectifier potassium channel 11target
LevosimendanATP-sensitive inward rectifier potassium channel 8target
LevosimendancGMP-inhibited 3',5'-cyclic phosphodiesterase Atarget
PhenoxybenzamineAlpha-1A adrenergic receptortarget
PhenoxybenzamineCalmodulintarget
PhenoxybenzamineSolute carrier family 22 member 2transporter
PhenoxybenzamineSolute carrier family 22 member 1transporter
PhenoxybenzamineSolute carrier family 22 member 3transporter
PhenoxybenzamineAlpha-2A adrenergic receptortarget
PhenoxybenzamineAlpha-2C adrenergic receptortarget
PhenoxybenzamineAlpha-2B adrenergic receptortarget
PhenoxybenzamineBeta-2 adrenergic receptortarget
PhenoxybenzamineAlpha-1B adrenergic receptortarget
PhenoxybenzamineAlpha-1D adrenergic receptortarget
PindololBeta-1 adrenergic receptortarget
PindololBeta-2 adrenergic receptortarget
Pindolol5-hydroxytryptamine receptor 1Atarget
Pindolol5-hydroxytryptamine receptor 1Btarget
PindololCytochrome P450 2D6enzyme
PindololBeta-3 adrenergic receptortarget
DipyridamolecAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10Atarget
DipyridamolecGMP-specific 3',5'-cyclic phosphodiesterasetarget
DipyridamolecAMP-specific 3',5'-cyclic phosphodiesterase 4Atarget
DipyridamoleAdenosine deaminasetarget
DipyridamoleMultidrug resistance-associated protein 4transporter
DipyridamoleMultidrug resistance-associated protein 5transporter
DipyridamoleP-glycoprotein 1transporter
DipyridamoleCalcipressin-1target
DipyridamoleAlpha-1-acid glycoprotein 1target
DipyridamoleSolute carrier organic anion transporter family member 1B1transporter
DipyridamoleSolute carrier organic anion transporter family member 1B3transporter
DipyridamoleSolute carrier organic anion transporter family member 2B1transporter
DipyridamoleBile salt export pumptransporter
Isosorbide mononitrateGuanylate cyclase soluble subunit alpha-2target
Isosorbide mononitrateGlutathione S-transferase Mu 1enzyme
Isosorbide mononitrateXanthine dehydrogenase/oxidaseenzyme
Isosorbide mononitrateAlcohol dehydrogenase class-3enzyme
FelodipineVoltage-dependent calcium channel subunit alpha-2/delta-1target
FelodipineCalmodulintarget
FelodipineCytochrome P450 3A4enzyme
FelodipineVoltage-dependent L-type calcium channel subunit alpha-1Ctarget
FelodipineVoltage-dependent L-type calcium channel subunit beta-2target
FelodipineCytochrome P450 2C8enzyme
FelodipineCalcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1Btarget
FelodipineCalcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1Atarget
FelodipineVoltage-dependent T-type calcium channel subunit alpha-1Htarget
FelodipineVoltage-dependent calcium channel subunit alpha-2/delta-2target
FelodipineTroponin C, skeletal muscletarget
FelodipineTroponin C, slow skeletal and cardiac musclestarget
FelodipineMineralocorticoid receptortarget
FelodipineVoltage-dependent L-type calcium channel subunit alpha-1Dtarget
FelodipineVoltage-dependent L-type calcium channel subunit alpha-1Starget
FelodipineCytochrome P450 3A5enzyme
FelodipineCytochrome P450 3A7enzyme
FelodipineP-glycoprotein 1transporter
FelodipineCytochrome P450 2C9enzyme
FelodipineCytochrome P450 2D6enzyme
FelodipineBile salt export pumptransporter
Ergoloid mesylateDopamine receptortarget
Ergoloid mesylateAlpha adrenergic receptortarget
Ergoloid mesylateBeta adrenergic receptortarget
Ergoloid mesylateSerotonin Receptorstarget
Ergoloid mesylateCytochrome P450 3A4enzyme
NitrendipineCytochrome P450 3A4enzyme
NitrendipineVoltage-dependent T-type calcium channel subunit alpha-1Htarget
NitrendipineVoltage-dependent calcium channel subunit alpha-2/delta-2target
NitrendipineVoltage-dependent L-type calcium channel subunit alpha-1Dtarget
NitrendipineVoltage-dependent L-type calcium channel subunit alpha-1Starget
NitrendipineVoltage-dependent L-type calcium channel subunit alpha-1Ctarget
NitrendipineVoltage-dependent calcium channel subunit alpha-2/delta-1target
NitrendipineVoltage-dependent L-type calcium channel subunit beta-2target
NitrendipineCytochrome P450 3A5enzyme
NitrendipineCytochrome P450 3A7enzyme
NitrendipineP-glycoprotein 1transporter
NitrendipineBile salt export pumptransporter
PerhexilineCarnitine O-palmitoyltransferase 1, liver isoformtarget
PerhexilineCarnitine O-palmitoyltransferase 2, mitochondrialtarget
PerhexilineCytochrome P450 2D6enzyme
PerhexilineCytochrome P450 2B6enzyme
PerhexilineCytochrome P450 3A4enzyme
PerhexilinePotassium voltage-gated channel subfamily H member 2target
IloprostProstacyclin receptortarget
IloprostTissue-type plasminogen activatortarget
IloprostcAMP-specific 3',5'-cyclic phosphodiesterase 4Atarget
IloprostSolute carrier organic anion transporter family member 2B1transporter
IloprostSolute carrier organic anion transporter family member 2A1transporter
IloprostSolute carrier organic anion transporter family member 3A1transporter
IloprostcAMP-specific 3',5'-cyclic phosphodiesterase 4Btarget
IloprostcAMP-specific 3',5'-cyclic phosphodiesterase 4Ctarget
IloprostcAMP-specific 3',5'-cyclic phosphodiesterase 4Dtarget
IloprostProstaglandin E2 receptor EP1 subtypetarget
IloprostProstaglandin D2 receptor 2target
PapaverinecAMP-specific 3',5'-cyclic phosphodiesterase 4Btarget
PapaverinecAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10Atarget
NifedipineCytochrome P450 3A4enzyme
NifedipineCytochrome P450 2E1enzyme
NifedipineCytochrome P450 2D6enzyme
NifedipineCalmodulintarget
NifedipineVoltage-dependent L-type calcium channel subunit alpha-1Dtarget
NifedipineVoltage-dependent L-type calcium channel subunit alpha-1Starget
NifedipineVoltage-dependent L-type calcium channel subunit alpha-1Ctarget
NifedipineVoltage-dependent L-type calcium channel subunit beta-2target
NifedipinePotassium voltage-gated channel subfamily D member 3target
NifedipineVoltage-dependent T-type calcium channeltarget
NifedipineCytochrome P450 1A2enzyme
NifedipineCytochrome P450 2A6enzyme
NifedipineCytochrome P450 2C8enzyme
NifedipineCanalicular multispecific organic anion transporter 2transporter
NifedipineP-glycoprotein 1transporter
NifedipineCanalicular multispecific organic anion transporter 1transporter
NifedipineCytochrome P450 1A1enzyme
NifedipineCytochrome P450 2B6enzyme
NifedipineNuclear receptor subfamily 1 group I member 2target
NifedipineSolute carrier organic anion transporter family member 1B1transporter
NifedipineBile salt export pumptransporter
NifedipineCytochrome P450 2C9enzyme
NifedipineSerum albumincarrier
Nifedipinealpha1-acid glycoproteincarrier
NifedipineCytochrome P450 3A5enzyme
TrimethaphanNeuronal acetylcholine receptor subunit alpha-10target
TrimethaphanCholinesteraseenzyme
AmiodaroneBeta adrenergic receptortarget
AmiodaroneHERG human cardiac K+ channeltarget
AmiodaroneCytochrome P450 2C8enzyme
AmiodaroneCytochrome P450 2C9enzyme
AmiodaroneCytochrome P450 2D6enzyme
AmiodaroneVoltage-dependent T-type calcium channel subunit alpha-1Itarget
AmiodaroneVoltage gated L-type calcium channeltarget
AmiodaroneCytochrome P450 3A4enzyme
AmiodaroneCytochrome P450 1A2enzyme
AmiodaroneCytochrome P450 1A1enzyme
AmiodaroneP-glycoprotein 1transporter
AmiodaroneCytochrome P450 2C19enzyme
AmiodaroneCytochrome P450 2A6enzyme
AmiodaroneThyroid hormone receptortarget
AmiodaronePeroxisome proliferator-activated receptor gammatarget
AmiodaroneBile salt export pumptransporter
AmiodaroneSolute carrier family 22 member 2transporter
AmiodaroneCytochrome P450 2J2enzyme
AmiodaronePeroxisome proliferator-activated receptor alphatarget
AmiodaronePeroxisome proliferator-activated receptor gamma coactivator 1-betatarget
AmiodaroneSerum albumincarrier
DiazoxideCarbonic anhydrase 1target
DiazoxideCarbonic anhydrase 2target
DiazoxideCalcium-activated potassium channel subunit alpha-1target
DiazoxideSodium/potassium-transporting ATPase subunit alpha-1target
DiazoxideATP-sensitive inward rectifier potassium channel 11target
DiazoxideGlutamine synthetaseenzyme
CarvedilolAlpha-1A adrenergic receptortarget
CarvedilolBeta-1 adrenergic receptortarget
CarvedilolNADH dehydrogenase [ubiquinone] 1 subunit C2target
CarvedilolBeta-2 adrenergic receptortarget
CarvedilolVascular endothelial growth factor Atarget
CarvedilolNatriuretic peptides Btarget
CarvedilolGap junction alpha-1 proteintarget
CarvedilolPotassium voltage-gated channel subfamily H member 2target
CarvedilolVascular cell adhesion protein 1target
CarvedilolCytochrome P450 2C9enzyme
CarvedilolCytochrome P450 2D6enzyme
CarvedilolXanthine dehydrogenase/oxidaseenzyme
CarvedilolP-glycoprotein 1transporter
CarvedilolCytochrome P450 1A2enzyme
CarvedilolCytochrome P450 3A4enzyme
CarvedilolCytochrome P450 1A1enzyme
CarvedilolCytochrome P450 2E1enzyme
CarvedilolAlpha-1D adrenergic receptortarget
CarvedilolAlpha-1B adrenergic receptortarget
CarvedilolAlpha-2C adrenergic receptortarget
CarvedilolAlpha-2B adrenergic receptortarget
CarvedilolAlpha-2A adrenergic receptortarget
CarvedilolE-selectintarget
CarvedilolHypoxia-inducible factor 1-alphatarget
CarvedilolInward rectifier potassium channel 4target
CarvedilolUDP-glucuronosyltransferase 1-1enzyme
CarvedilolSerum albumincarrier
CarvedilolUDP-glucuronosyltransferase 2B4enzyme
CarvedilolUDP-glucuronosyltransferase 2B7enzyme
CarvedilolInward rectifier potassium channel 2target
CarvedilolAlpha-1 adrenergic receptorstarget
CilostazolcGMP-inhibited 3',5'-cyclic phosphodiesterase Atarget
CilostazolCytochrome P450 2C19enzyme
CilostazolCytochrome P450 3A4enzyme
CilostazolCytochrome P450 3A5enzyme
CilostazolCytochrome P450 3A7enzyme
CilostazolCytochrome P450 1A2enzyme
CilostazolCytochrome P450 2D6enzyme
BepridilVoltage-dependent P/Q-type calcium channel subunit alpha-1Atarget
BepridilSodium/potassium-transporting ATPase subunit alpha-1target
BepridilPotassium voltage-gated channel subfamily KQT member 1target
BepridilTroponin C, slow skeletal and cardiac musclestarget
BepridilCalmodulintarget
BepridilVoltage-dependent T-type calcium channel subunit alpha-1Htarget
BepridilVoltage-dependent calcium channel subunit alpha-2/delta-2target
BepridilCalcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1Btarget
BepridilCalcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1Atarget
BepridilP-glycoprotein 1transporter
BepridilCytochrome P450 2D6enzyme
BepridilPotassium voltage-gated channel subfamily H member 2target
BepridilCytochrome P450 3A4enzyme
HydralazineMembrane primary amine oxidasetarget
HydralazineProlyl 4-hydroxylase subunit alpha-1target
HydralazineCytochrome P450 3A4enzyme
HydralazineSerum albumincarrier
HydralazineHypoxia-inducible factor 1-alphatarget
MibefradilVoltage-dependent T-type calcium channel subunit alpha-1Gtarget
MibefradilVoltage-dependent T-type calcium channel subunit alpha-1Htarget
MibefradilVoltage-dependent L-type calcium channel subunit alpha-1Ctarget
MibefradilVoltage-dependent L-type calcium channel subunit beta-1target
MibefradilCytochrome P450 3A4enzyme
MibefradilCytochrome P450 1A2enzyme
MibefradilCytochrome P450 2D6enzyme
MibefradilCytochrome P450 3A5enzyme
MibefradilCytochrome P450 3A7enzyme
MibefradilP-glycoprotein 1transporter
MibefradilVoltage-dependent T-type calcium channel subunit alpha-1Itarget
MibefradilVoltage-dependent L-type calcium channel subunit alpha-1Starget
MibefradilVoltage-dependent L-type calcium channel subunit alpha-1Ftarget
MibefradilVoltage-dependent L-type calcium channel subunit alpha-1Dtarget
MibefradilVoltage-dependent L-type calcium channel subunit beta-2target
MibefradilVoltage-dependent L-type calcium channel subunit beta-3target
MibefradilVoltage-dependent L-type calcium channel subunit beta-4target
MibefradilCytochrome P450 11B1, mitochondrialenzyme
MibefradilCytochrome P450 11B2, mitochondrialenzyme
TheobromineCytochrome P450 1A2enzyme
TheobromineCytochrome P450 2E1enzyme
TheobromineAdenosine receptor A1target
TheobromineAdenosine receptor A2atarget
TheobrominecAMP-specific 3',5'-cyclic phosphodiesterase 4Btarget
AmrinoneTumor necrosis factortarget
AmrinonecGMP-inhibited 3',5'-cyclic phosphodiesterase Atarget
AmrinonecGMP-inhibited 3',5'-cyclic phosphodiesterase Btarget
AmrinonecAMP-specific 3',5'-cyclic phosphodiesterase 4target
AmrinonecAMP-specific 3',5'-cyclic phosphodiesterase 3target
OxprenololBeta-1 adrenergic receptortarget
OxprenololBeta-2 adrenergic receptortarget
OxprenololSolute carrier family 22 member 2transporter
OxprenololCytochrome P450 2D6enzyme
OxprenololBeta-3 adrenergic receptortarget
Amyl NitriteAtrial natriuretic peptide receptor 1target
Amyl NitriteAldehyde dehydrogenase, mitochondrialenzyme
Erythrityl tetranitrateAtrial natriuretic peptide receptor 1target
Erythrityl tetranitrateAtrial natriuretic peptide receptor 2target
ColforsinP-glycoprotein 1transporter
ColforsinAdenylate cyclase type 2target
ColforsinGuanine nucleotide-binding protein G(s) subunit alpha isoforms shorttarget
ColforsinAdenylate cyclase type 5target
ColforsinCystic fibrosis transmembrane conductance regulatortarget
ResveratrolTransthyretincarrier
ResveratrolRibosyldihydronicotinamide dehydrogenase [quinone]target
ResveratrolProstaglandin G/H synthase 1target
ResveratrolCasein kinase II subunit alphatarget
ResveratrolProstaglandin G/H synthase 2target
ResveratrolNAD-dependent protein deacetylase sirtuin-1target
ResveratrolCytochrome P450 1A1enzyme
ResveratrolCytochrome P450 3A4enzyme
ResveratrolCytochrome P450 1A2enzyme
ResveratrolCytochrome P450 1B1enzyme
ResveratrolArachidonate 15-lipoxygenasetarget
ResveratrolArachidonate 5-lipoxygenasetarget
ResveratrolAryl hydrocarbon receptortarget
ResveratrolPhosphatidylinositol 4-kinase type 2-betatarget
ResveratrolIntegrin alpha-5target
ResveratrolIntegrin beta-3target
ResveratrolSerum albumincarrier
ResveratrolAmyloid beta A4 proteintarget
ResveratrolAlpha-synucleintarget
ResveratrolEstrogen receptor alphatarget
ResveratrolMelatonin receptor type 1Atarget
ResveratrolMelatonin receptor type 1Btarget
ResveratrolC-type lectin domain family 14 member Atarget
ResveratrolNuclear receptor subfamily 1 group I member 2target
ResveratrolNuclear receptor subfamily 1 group I member 3target
ResveratrolSolute carrier family 2, facilitated glucose transporter member 1target
ResveratrolCarbonyl reductase [NADPH] 1target
ResveratrolPeroxisome proliferator-activated receptor alphatarget
ResveratrolPeroxisome proliferator-activated receptor gammatarget
ResveratrolRAC-alpha serine/threonine-protein kinasetarget
ResveratrolFar upstream element-binding protein 2target
ResveratrolTyrosine--tRNA ligase, cytoplasmictarget
AcetylcholineAcetylcholinesterasetarget
AcetylcholineSolute carrier family 22 member 5transporter
AcetylcholineSolute carrier family 22 member 1transporter
AcetylcholineMuscarinic acetylcholine receptor M1target
AcetylcholineMuscarinic acetylcholine receptor M2target
AcetylcholineMuscarinic acetylcholine receptor M3target
AcetylcholineMuscarinic acetylcholine receptor M4target
AcetylcholineNeuronal acetylcholine receptor subunit alpha-7target
N-(6-Aminohexyl)-5-Chloro-1-NaphthalenesulfonamideCalmodulintarget
N-(6-Aminohexyl)-5-Chloro-1-NaphthalenesulfonamideTroponin C, slow skeletal and cardiac musclestarget
N-(6-Aminohexyl)-5-Chloro-1-NaphthalenesulfonamideTroponin I, cardiac muscletarget
PrenylamineCalmodulintarget
PrenylamineMyosin light chain kinase 2, skeletal/cardiac muscletarget
PrenylamineCytochrome P450 3A4enzyme
CyclandelateVoltage-dependent calcium channel subunit alpha-2/delta-1target
CyclandelateLiver carboxylesterase 1target
CyclandelateCytochrome P450 3A4enzyme
FlunarizineHistamine H1 receptortarget
FlunarizineVoltage-dependent T-type calcium channel subunit alpha-1Gtarget
FlunarizineVoltage-dependent T-type calcium channel subunit alpha-1Htarget
FlunarizineVoltage-dependent T-type calcium channel subunit alpha-1Itarget
FlunarizineCalmodulintarget
FlunarizineCytochrome P450 2D6enzyme
FlunarizineCytochrome P450 2C9enzyme
FlunarizineCytochrome P450 1A1enzyme
FlunarizineCytochrome P450 1A2enzyme
FlunarizineCytochrome P450 2A6enzyme
FlunarizineCytochrome P450 3A4enzyme
CeliprololBeta-1 adrenergic receptortarget
CeliprololBeta-2 adrenergic receptortarget
CeliprololBeta-3 adrenergic receptortarget
CeliprololAlpha-2A adrenergic receptortarget
CeliprololAlpha-2B adrenergic receptortarget
CeliprololAlpha-2C adrenergic receptortarget
CeliprololCytochrome P450 2D6enzyme
NebivololBeta-1 adrenergic receptortarget
NebivololCytochrome P450 2D6enzyme
NebivololBeta-2 adrenergic receptortarget
NebivololCytochrome P450 3A4enzyme
NebivololSerum albumincarrier
NebivololBeta-3 adrenergic receptortarget
NebivololCytochrome P450 2C19enzyme
EnoximonecGMP-inhibited 3',5'-cyclic phosphodiesterase Atarget
BeraprostProstacyclin receptortarget
BeraprostCytochrome P450 2C8enzyme
IbudilastcAMP-specific 3',5'-cyclic phosphodiesterase 4Atarget
IbudilastcGMP-inhibited 3',5'-cyclic phosphodiesterase Atarget
IbudilastcAMP-specific 3',5'-cyclic phosphodiesterase 4Btarget
IbudilastcAMP-specific 3',5'-cyclic phosphodiesterase 4Ctarget
IbudilastcAMP-specific 3',5'-cyclic phosphodiesterase 4Dtarget
NylidrinCatechol O-methyltransferaseenzyme
NylidrinVoltage-dependent T-type calcium channel subunit alpha-1Itarget
NylidrinInterferon alpha/beta receptor 2target
NylidrinCytochrome P450 3A4enzyme
Pentaerythritol tetranitrateHemoglobin subunit alphatarget
Pentaerythritol tetranitrateHemoglobin subunit betatarget
Pentaerythritol tetranitrateGuanylate cyclase soluble subunit alpha-2enzyme
Pentaerythritol tetranitrateFree radicalstarget
Pentaerythritol tetranitrateNitric oxide synthase, endothelialenzyme
Pentaerythritol tetranitrateAldehyde dehydrogenase, mitochondrialenzyme
Dotarizine5-hydroxytryptamine receptor 2Atarget
Dotarizine5-hydroxytryptamine receptor 1Atarget
DotarizineVoltage-dependent P/Q-type calcium channel subunit alpha-1Atarget
Dotarizine5-hydroxytryptamine receptor 2Ctarget
DotarizineCytochrome P450 3A4enzyme
TezosentanEndothelin-1 receptortarget
TezosentanEndothelin B receptortarget
XylometazolineAlpha-2A adrenergic receptortarget
XylometazolineAlpha-1A adrenergic receptortarget
XylometazolineAlpha-1B adrenergic receptortarget
XylometazolineAlpha-1D adrenergic receptortarget
XylometazolineAlpha-2B adrenergic receptortarget
XylometazolineAlpha-2C adrenergic receptortarget
BetahistineHistamine H1 receptortarget
BetahistineHistamine H3 receptortarget
DrotaverinecAMP-specific 3',5'-cyclic phosphodiesterase 4Atarget
DrotaverineVoltage-dependent L-type calcium channel subunit alpha-1Ctarget
PinacidilCytochrome P450 3A4enzyme
Inositol nicotinateSodium-coupled monocarboxylate transporter 1transporter
Inositol nicotinateATP synthase subunit beta, mitochondrialenzyme
Inositol nicotinateHydroxycarboxylic acid receptor 3target
Inositol nicotinateHydroxycarboxylic acid receptor 2target
Inositol nicotinateDiacylglycerol O-acyltransferase 2enzyme
IndenololCytochrome P450 2D6enzyme
IfenprodilGlutamate receptor ionotropic, NMDA 1target
IfenprodilGlutamate receptor ionotropic, NMDA 2Btarget
EperisoneCytochrome P450 3A4enzyme
Trimetazidine3-ketoacyl-CoA thiolase, peroxisomaltarget
Xanthinol60S ribosomal protein L3target
XanthinolNAD(P) transhydrogenase, mitochondrialtarget
XanthinolGlyceraldehyde-3-phosphate dehydrogenasetarget
XanthinolIsocitrate dehydrogenase [NAD] subunit alpha, mitochondrialtarget
Xanthinol2-oxoglutarate dehydrogenase, mitochondrialtarget
XanthinolMalate dehydrogenase, mitochondrialtarget
MoxisylyteCholinesteraseenzyme
MoxisylyteCytochrome P450 3A Subfamilyenzyme
MoxisylyteAlpha adrenergic receptortarget
NicorandilATP-binding cassette sub-family C member 9target
BenidipineVoltage-dependent L-type calcium channeltarget
BenidipineVoltage-dependent N-type calcium channel subunit alpha-1Btarget
BenidipineVoltage-dependent T-type calcium channeltarget
BenidipineCytochrome P450 3A4enzyme
BenidipineCytochrome P450 3A5enzyme
MolsidomineGuanylate cyclase soluble subunit alpha-2target
MolsidomineGuanylate cyclase soluble subunit alpha-2enzyme
MolsidominecGMP-specific 3',5'-cyclic phosphodiesteraseenzyme
TrapidilPlatelet-derived growth factor receptor betatarget
TrapidilCyclic nucleotide phosphodiesterasetarget
PimobendanCytochrome P450 1A2enzyme
AnisodamineCytochrome P450 2D6enzyme
VinpocetineCytochrome P450 3A4enzyme
BucindololCytochrome P450 2D6enzyme
BamifyllineCytochrome P450 1A2enzyme
DihydroergocristineSerotonin Receptorstarget
DihydroergocristineBeta adrenergic receptortarget
DihydroergocristineAlpha adrenergic receptortarget
DihydroergocristineDopamine receptortarget
DihydroergocristineBile salt export pumptransporter
DihydroergocristineCytochrome P450 3A4enzyme
DihydroergocryptineCytochrome P450 3A4enzyme
BencyclaneCytochrome P450 3A4enzyme
LidoflazineCytochrome P450 3A4enzyme
BufyllineCytochrome P450 1A2enzyme
TreprostinilP2Y purinoceptor 12target
TreprostinilPeroxisome proliferator-activated receptor deltatarget
TreprostinilProstacyclin receptortarget
TreprostinilCytochrome P450 2C9enzyme
BosentanEndothelin B receptortarget
BosentanEndothelin-1 receptortarget
BosentanCytochrome P450 3A4enzyme
BosentanCytochrome P450 2C9enzyme
BosentanBile salt export pumptransporter
EpoprostenolP2Y purinoceptor 12target
EpoprostenolProstacyclin receptortarget
EpoprostenolProstacyclin synthasetarget
AmbrisentanEndothelin B receptortarget
AmbrisentanEndothelin-1 receptortarget
AmbrisentanCytochrome P450 2C19enzyme
AmbrisentanCytochrome P450 3A4enzyme
AmbrisentanUDP-glucuronosyltransferase 1-9enzyme
AmbrisentanUDP-glucuronosyltransferase 1-3enzyme
AmbrisentanUDP-glucuronosyltransferase 2B7enzyme
AmbrisentanP-glycoprotein 1transporter
AmbrisentanSolute carrier organic anion transporter family member 1B1transporter
AmbrisentanSolute carrier organic anion transporter family member 1B3transporter
AmbrisentanCytochrome P450 3A5enzyme
RiociguatSerum albumincarrier
RiociguatAlpha-1-acid glycoprotein 1carrier
RiociguatGuanylate cyclase soluble subunit alpha-2target
RiociguatATP-binding cassette sub-family G member 2transporter
RiociguatCytochrome P450 1A1enzyme
RiociguatCytochrome P450 3A4enzyme
RiociguatCytochrome P450 2C8enzyme
RiociguatCytochrome P450 2J2enzyme
MacitentanCytochrome P450 3A4enzyme
MacitentanCytochrome P450 2C19enzyme
MacitentanEndothelin-1 receptortarget
MacitentanEndothelin B receptortarget
MacitentanSerum albumincarrier
SelexipagProstacyclin receptortarget
SelexipagLiver carboxylesterase 1enzyme
SelexipagCytochrome P450 2C8enzyme
SelexipagCytochrome P450 3A4enzyme
SelexipagSolute carrier organic anion transporter family member 1B1transporter
SelexipagSolute carrier organic anion transporter family member 1B3transporter
SelexipagP-glycoprotein 1transporter
UdenafilcGMP-specific 3',5'-cyclic phosphodiesterasetarget
UdenafilCytochrome P450 3A4enzyme
UdenafilCytochrome P450 3A5enzyme
MirodenafilCytochrome P450 3A Subfamilyenzyme
AvanafilcGMP-specific 3',5'-cyclic phosphodiesterasetarget
AvanafilCytochrome P450 3A4enzyme
FostamatinibAdenosine receptor A3target
Fostamatinibvesicular monoamine transporter 2 (VMAT2)target
FostamatinibFatty-acid amide hydrolase 1target
FostamatinibEquilibrative nucleoside transporter 1target
FostamatinibUDP-glucuronosyltransferase 1-1target
FostamatinibcGMP-specific 3',5'-cyclic phosphodiesterasetarget
FostamatinibArachidonate 5-lipoxygenasetarget
FostamatinibCathepsin Starget
FostamatinibCathepsin L1target
FostamatinibTyrosine-protein kinase ABL1target
FostamatinibCalcium-dependent protein kinase 1target
FostamatinibSerine/threonine-protein kinase PknBtarget
FostamatinibRibosomal protein S6 kinase alpha-6target
FostamatinibNon-receptor tyrosine-protein kinase TYK2target
FostamatinibAtypical kinase COQ8A, mitochondrialtarget
FostamatinibTyrosine-protein kinase JAK1target
FostamatinibHepatocyte growth factor receptortarget
FostamatinibSerine/threonine-protein kinase NIM1target
FostamatinibSerine/threonine-protein kinase MST4target
FostamatinibcAMP-dependent protein kinase catalytic subunit alphatarget
FostamatinibSerine/threonine-protein kinase 24target
FostamatinibSerine/threonine-protein kinase 3target
FostamatinibTyrosine-protein kinase Tectarget
FostamatinibTyrosine-protein kinase SYKtarget
FostamatinibSerine/threonine-protein kinase 33target
FostamatinibSerine/threonine-protein kinase 35target
FostamatinibSerine/threonine-protein kinase 36target
FostamatinibSerine/threonine-protein kinase 38target
FostamatinibSerine/threonine-protein kinase 38-liketarget
FostamatinibSTE20/SPS1-related proline-alanine-rich protein kinasetarget
FostamatinibSerine/threonine-protein kinase TAO1target
FostamatinibSerine/threonine-protein kinase TAO2target
FostamatinibSerine/threonine-protein kinase TAO3target
FostamatinibSerine/threonine-protein kinase TBK1target
FostamatinibAngiopoietin-1 receptortarget
FostamatinibDual specificity testis-specific protein kinase 1target
FostamatinibTGF-beta receptor type-1target
FostamatinibTGF-beta receptor type-2target
FostamatinibTyrosine-protein kinase receptor Tie-1target
FostamatinibSerine/threonine-protein kinase tousled-like 1target
FostamatinibSerine/threonine-protein kinase tousled-like 2target
FostamatinibTRAF2 and NCK-interacting protein kinasetarget
FostamatinibNon-receptor tyrosine-protein kinase TNK1target
FostamatinibActivated CDC42 kinase 1target
FostamatinibSerine/threonine-protein kinase TNNI3Ktarget
FostamatinibTestis-specific serine/threonine-protein kinase 1target
FostamatinibDual specificity protein kinase TTKtarget
FostamatinibTyrosine-protein kinase TXKtarget
FostamatinibTyrosine-protein kinase receptor TYRO3target
FostamatinibSerine/threonine-protein kinase ULK1target
FostamatinibSerine/threonine-protein kinase ULK2target
FostamatinibSerine/threonine-protein kinase ULK3target
FostamatinibWee1-like protein kinasetarget
FostamatinibTyrosine-protein kinase Yestarget
FostamatinibMitogen-activated protein kinase kinase kinase 19target
FostamatinibMitogen-activated protein kinase kinase kinase MLTtarget
FostamatinibTyrosine-protein kinase ZAP-70target
FostamatinibAP2-associated protein kinase 1target
FostamatinibAbelson tyrosine-protein kinase 2target
FostamatinibActivin receptor type-1target
FostamatinibActivin receptor type-1Btarget
FostamatinibAtypical kinase COQ8B, mitochondrialtarget
FostamatinibALK tyrosine kinase receptortarget
FostamatinibAnkyrin repeat and protein kinase domain-containing protein 1target
FostamatinibAurora kinase Atarget
FostamatinibAurora kinase Btarget
FostamatinibAurora kinase Ctarget
FostamatinibTyrosine-protein kinase receptor UFOtarget
FostamatinibTyrosine-protein kinase Blktarget
FostamatinibBMP-2-inducible protein kinasetarget
FostamatinibBone morphogenetic protein receptor type-1Btarget
FostamatinibBone morphogenetic protein receptor type-2target
FostamatinibCytoplasmic tyrosine-protein kinase BMXtarget
FostamatinibSerine/threonine-protein kinase B-raftarget
FostamatinibTyrosine-protein kinase BTKtarget
FostamatinibCalcium/calmodulin-dependent protein kinase type 1target
FostamatinibCalcium/calmodulin-dependent protein kinase type 1Dtarget
FostamatinibCalcium/calmodulin-dependent protein kinase type 1Gtarget
FostamatinibCalcium/calmodulin-dependent protein kinase type II subunit alphatarget
FostamatinibCalcium/calmodulin-dependent protein kinase type II subunit betatarget
FostamatinibCalcium/calmodulin-dependent protein kinase type II subunit deltatarget
FostamatinibCalcium/calmodulin-dependent protein kinase type II subunit gammatarget
FostamatinibCalcium/calmodulin-dependent protein kinase kinase 1target
FostamatinibCalcium/calmodulin-dependent protein kinase kinase 2target
FostamatinibPeripheral plasma membrane protein CASKtarget
FostamatinibKappa-caseintarget
FostamatinibCyclin-dependent kinase 1target
FostamatinibSerine/threonine-protein kinase MRCK gammatarget
FostamatinibCyclin-dependent kinase 4target
FostamatinibCyclin-dependent kinase-like 1target
FostamatinibCyclin-dependent kinase-like 2target
FostamatinibSerine/threonine-protein kinase Chk1target
FostamatinibSerine/threonine-protein kinase Chk2target
FostamatinibCitron Rho-interacting kinasetarget
FostamatinibDual specificity protein kinase CLK1target
FostamatinibDual specificity protein kinase CLK2target
FostamatinibDual specificity protein kinase CLK3target
FostamatinibDual specificity protein kinase CLK4target
FostamatinibMacrophage colony-stimulating factor 1 receptortarget
FostamatinibTyrosine-protein kinase CSKtarget
FostamatinibCasein kinase I isoform alphatarget
FostamatinibCasein kinase II subunit alphatarget
FostamatinibCasein kinase II subunit alpha'target
FostamatinibDeath-associated protein kinase 1target
FostamatinibDeath-associated protein kinase 2target
FostamatinibDeath-associated protein kinase 3target
FostamatinibSerine/threonine-protein kinase DCLK1target
FostamatinibSerine/threonine-protein kinase DCLK2target
FostamatinibSerine/threonine-protein kinase DCLK3target
FostamatinibEpithelial discoidin domain-containing receptor 1target
FostamatinibDiscoidin domain-containing receptor 2target
FostamatinibDual specificity tyrosine-phosphorylation-regulated kinase 1Atarget
FostamatinibDual specificity tyrosine-phosphorylation-regulated kinase 1Btarget
FostamatinibEpidermal growth factor receptortarget
FostamatinibEukaryotic translation initiation factor 2-alpha kinase 1target
FostamatinibInterferon-induced, double-stranded RNA-activated protein kinasetarget
FostamatinibeIF-2-alpha kinase GCN2target
FostamatinibEphrin type-A receptor 1target
FostamatinibEphrin type-A receptor 2target
FostamatinibEphrin type-A receptor 3target
FostamatinibEphrin type-A receptor 4target
FostamatinibEphrin type-A receptor 5target
FostamatinibEphrin type-A receptor 6target
FostamatinibEphrin type-A receptor 7target
FostamatinibEphrin type-A receptor 8target
FostamatinibEphrin type-B receptor 1target
FostamatinibEphrin type-B receptor 2target
FostamatinibEphrin type-B receptor 4target
FostamatinibEphrin type-B receptor 6target
FostamatinibReceptor tyrosine-protein kinase erbB-2target
FostamatinibReceptor tyrosine-protein kinase erbB-4target
FostamatinibSerine/threonine-protein kinase/endoribonuclease IRE1target
FostamatinibTyrosine-protein kinase Fertarget
FostamatinibTyrosine-protein kinase Fes/Fpstarget
FostamatinibFibroblast growth factor receptor 1target
FostamatinibFibroblast growth factor receptor 2target
FostamatinibFibroblast growth factor receptor 3target
FostamatinibTyrosine-protein kinase Fgrtarget
FostamatinibVascular endothelial growth factor receptor 1target
FostamatinibReceptor-type tyrosine-protein kinase FLT3target
FostamatinibVascular endothelial growth factor receptor 3target
FostamatinibSerine/threonine-protein kinase mTORtarget
FostamatinibTyrosine-protein kinase FRKtarget
FostamatinibTyrosine-protein kinase Fyntarget
FostamatinibCyclin-G-associated kinasetarget
FostamatinibGlycogen synthase kinase-3 alphatarget
FostamatinibGlycogen synthase kinase-3 betatarget
FostamatinibTyrosine-protein kinase HCKtarget
FostamatinibHomeodomain-interacting protein kinase 2target
FostamatinibHomeodomain-interacting protein kinase 3target
FostamatinibSerine/threonine-protein kinase ICKtarget
FostamatinibInhibitor of nuclear factor kappa-B kinase subunit betatarget
FostamatinibInhibitor of nuclear factor kappa-B kinase subunit epsilontarget
FostamatinibInsulin receptortarget
FostamatinibInsulin receptor-related proteintarget
FostamatinibInterleukin-1 receptor-associated kinase 1target
FostamatinibInterleukin-1 receptor-associated kinase 3target
FostamatinibInterleukin-1 receptor-associated kinase 4target
FostamatinibTyrosine-protein kinase ITK/TSKtarget
FostamatinibTyrosine-protein kinase JAK2target
FostamatinibTyrosine-protein kinase JAK3target
FostamatinibVascular endothelial growth factor receptor 2target
FostamatinibSerine/threonine-protein kinase SIK3target
FostamatinibMast/stem cell growth factor receptor Kittarget
FostamatinibSerine/threonine-protein kinase LATS1target
FostamatinibTyrosine-protein kinase Lcktarget
FostamatinibLIM domain kinase 1target
FostamatinibLIM domain kinase 2target
FostamatinibLeucine-rich repeat serine/threonine-protein kinase 2target
FostamatinibLeukocyte tyrosine kinase receptortarget
FostamatinibTyrosine-protein kinase Lyntarget
FostamatinibDual specificity mitogen-activated protein kinase kinase 2target
FostamatinibDual specificity mitogen-activated protein kinase kinase 3target
FostamatinibDual specificity mitogen-activated protein kinase kinase 5target
FostamatinibDual specificity mitogen-activated protein kinase kinase 6target
FostamatinibMitogen-activated protein kinase kinase kinase 1target
FostamatinibMitogen-activated protein kinase kinase kinase 10target
FostamatinibMitogen-activated protein kinase kinase kinase 11target
FostamatinibMitogen-activated protein kinase kinase kinase 12target
FostamatinibMitogen-activated protein kinase kinase kinase 13target
FostamatinibMitogen-activated protein kinase kinase kinase 15target
FostamatinibMitogen-activated protein kinase kinase kinase 2target
FostamatinibMitogen-activated protein kinase kinase kinase 3target
FostamatinibMitogen-activated protein kinase kinase kinase 4target
FostamatinibMitogen-activated protein kinase kinase kinase 6target
FostamatinibMitogen-activated protein kinase kinase kinase 9target
FostamatinibMitogen-activated protein kinase kinase kinase kinase 1target
FostamatinibMitogen-activated protein kinase kinase kinase kinase 2target
FostamatinibMitogen-activated protein kinase kinase kinase kinase 3target
FostamatinibMitogen-activated protein kinase kinase kinase kinase 4target
FostamatinibMitogen-activated protein kinase kinase kinase kinase 5target
FostamatinibMitogen-activated protein kinase 10target
FostamatinibMitogen-activated protein kinase 13target
FostamatinibMitogen-activated protein kinase 14target
FostamatinibMitogen-activated protein kinase 15target
FostamatinibMitogen-activated protein kinase 4target
FostamatinibMitogen-activated protein kinase 7target
FostamatinibMitogen-activated protein kinase 9target
FostamatinibMAP kinase-activated protein kinase 5target
FostamatinibSerine/threonine-protein kinase MARK1target
FostamatinibSerine/threonine-protein kinase MARK2target
FostamatinibMAP/microtubule affinity-regulating kinase 3target
FostamatinibMAP/microtubule affinity-regulating kinase 4target
FostamatinibCLIP-associating protein 1target
FostamatinibMicrotubule-associated serine/threonine-protein kinase 1target
FostamatinibMegakaryocyte-associated tyrosine-protein kinasetarget
FostamatinibMaternal embryonic leucine zipper kinasetarget
FostamatinibTyrosine-protein kinase Mertarget
FostamatinibMisshapen-like kinase 1target
FostamatinibMAP kinase-interacting serine/threonine-protein kinase 1target
FostamatinibMAP kinase-interacting serine/threonine-protein kinase 2target
FostamatinibMacrophage-stimulating protein receptortarget
FostamatinibMuscle, skeletal receptor tyrosine-protein kinasetarget
FostamatinibMyosin light chain kinase, smooth muscletarget
FostamatinibMyosin light chain kinase 2, skeletal/cardiac muscletarget
FostamatinibMyosin light chain kinase 3target
FostamatinibMyosin light chain kinase family member 4target
FostamatinibMyosin-IIIatarget
FostamatinibSerine/threonine-protein kinase Nek1target
FostamatinibSerine/threonine-protein kinase Nek11target
FostamatinibSerine/threonine-protein kinase Nek2target
FostamatinibSerine/threonine-protein kinase Nek3target
FostamatinibSerine/threonine-protein kinase Nek4target
FostamatinibSerine/threonine-protein kinase Nek5target
FostamatinibSerine/threonine-protein kinase Nek9target
FostamatinibHigh affinity nerve growth factor receptortarget
FostamatinibBDNF/NT-3 growth factors receptortarget
FostamatinibNT-3 growth factor receptortarget
FostamatinibNUAK family SNF1-like kinase 1target
FostamatinibNUAK family SNF1-like kinase 2target
FostamatinibSerine/threonine-protein kinase OSR1target
FostamatinibSerine/threonine-protein kinase PAK 1target
FostamatinibSerine/threonine-protein kinase PAK 2target
FostamatinibSerine/threonine-protein kinase PAK 3target
FostamatinibSerine/threonine-protein kinase PAK 4target
FostamatinibSerine/threonine-protein kinase PAK 6target
FostamatinibSerine/threonine-protein kinase PAK 5target
FostamatinibCyclin-dependent kinase 16target
FostamatinibCyclin-dependent kinase 17target
FostamatinibPlatelet-derived growth factor receptor alphatarget
FostamatinibPlatelet-derived growth factor receptor betatarget
Fostamatinib3-phosphoinositide-dependent protein kinase 1target
FostamatinibCyclin-dependent kinase 15target
FostamatinibPhosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoformtarget
FostamatinibPhosphatidylinositol 4-kinase betatarget
FostamatinibPhosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit betatarget
FostamatinibPhosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gammatarget
FostamatinibPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoformtarget
FostamatinibPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoformtarget
FostamatinibSerine/threonine-protein kinase pim-1target
FostamatinibSerine/threonine-protein kinase pim-3target
FostamatinibPhosphatidylinositol 5-phosphate 4-kinase type-2 betatarget
FostamatinibPhosphatidylinositol 5-phosphate 4-kinase type-2 gammatarget
FostamatinibMembrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinasetarget
FostamatinibSerine/threonine-protein kinase N1target
FostamatinibSerine/threonine-protein kinase N2target
FostamatinibSerine/threonine-protein kinase PLK1target
FostamatinibSerine/threonine-protein kinase PLK2target
FostamatinibSerine/threonine-protein kinase PLK3target
FostamatinibSerine/threonine-protein kinase PLK4target
Fostamatinib5'-AMP-activated protein kinase catalytic subunit alpha-1target
Fostamatinib5'-AMP-activated protein kinasetarget
FostamatinibcAMP-dependent protein kinase catalytic subunit betatarget
FostamatinibProtein kinase C delta typetarget
FostamatinibProtein kinase C epsilon typetarget
FostamatinibProtein kinase C gamma type (PRKCG)target
FostamatinibProtein kinase C iota typetarget
FostamatinibProtein kinase C theta typetarget
FostamatinibSerine/threonine-protein kinase D1target
FostamatinibcGMP-dependent protein kinase 2target
FostamatinibSerine/threonine-protein kinase PRP4 homologtarget
FostamatinibFocal adhesion kinase 1target
FostamatinibProtein-tyrosine kinase 2-betatarget
FostamatinibProtein-tyrosine kinase 6target
FostamatinibRAF proto-oncogene serine/threonine-protein kinasetarget
FostamatinibProto-oncogene tyrosine-protein kinase receptor Rettarget
FostamatinibSerine/threonine-protein kinase RIO1target
FostamatinibSerine/threonine-protein kinase RIO2target
FostamatinibSerine/threonine-protein kinase RIO3target
FostamatinibReceptor-interacting serine/threonine-protein kinase 1target
FostamatinibReceptor-interacting serine/threonine-protein kinase 2target
FostamatinibReceptor-interacting serine/threonine-protein kinase 4target
FostamatinibRho-associated protein kinase 2target
FostamatinibProto-oncogene tyrosine-protein kinase ROStarget
FostamatinibRibosomal protein S6 kinase alpha-1target
FostamatinibRibosomal protein S6 kinase alpha-3target
FostamatinibSerine/threonine-protein kinase SBK1target
FostamatinibUncharacterized serine/threonine-protein kinase SBK3target
FostamatinibSerine/threonine-protein kinase Sgk3target
FostamatinibSerine/threonine-protein kinase SIK1target
FostamatinibSerine/threonine-protein kinase SIK2target
FostamatinibSTE20-like serine/threonine-protein kinasetarget
FostamatinibSNF-related serine/threonine-protein kinasetarget
FostamatinibProto-oncogene tyrosine-protein kinase Srctarget
FostamatinibTyrosine-protein kinase Srmstarget
FostamatinibSerine/threonine-protein kinase 10target
FostamatinibSerine/threonine-protein kinase 16target
FostamatinibSerine/threonine-protein kinase 17Atarget
FostamatinibSerine/threonine-protein kinase 17Btarget
FostamatinibSerine/threonine-protein kinase 32Atarget
FostamatinibCytochrome P450 3A4enzyme
FostamatinibATP-binding cassette sub-family G member 2transporter
FostamatinibATP-binding cassette sub-family B member 5transporter
FostamatinibUDP-glucuronosyltransferase 1-9enzyme
LefradafibanIntegrin alpha-IIbtarget
LefradafibanIntegrin beta-3target
RanolazineCytochrome P450 3A4enzyme
RanolazineCytochrome P450 2D6enzyme
RanolazineBile salt export pumptransporter
RanolazineP-glycoprotein 1transporter
RanolazineSodium channel proteintarget
RanolazineInward rectifier potassium channeltarget
RanolazineVoltage gated L-type calcium channeltarget
RanolazineAlpha-1 adrenergic receptorstarget
RanolazineBeta-1 adrenergic receptortarget
RanolazineFatty acidtarget
RanolazineAlpha-1-acid glycoprotein 1carrier
RanolazineMultidrug and toxin extrusion protein 1transporter
RanolazineMultidrug and toxin extrusion protein 2transporter
AgmatineSolute carrier family 22 member 1transporter
AgmatineSolute carrier family 22 member 2transporter
AgmatineSolute carrier family 22 member 3transporter
AgmatineAlpha-2C adrenergic receptortarget
AgmatineNischarintarget
AgmatineAcetylcholine receptor subunit alphatarget
AgmatineGlutamate receptor ionotropic, NMDA 1target
AgmatineATP-sensitive inward rectifier potassium channel 1target
AgmatineVoltage-dependent N-type calcium channel subunit alpha-1Btarget
AgmatineAcid-sensing ion channel 3target
AgmatineY+L amino acid transporter 1transporter
AgmatineCytochrome P450 3A4enzyme
AranidipineVoltage-dependent L-type calcium channel subunit alpha-1Ctarget
AranidipineVoltage-dependent L-type calcium channel subunit alpha-1Dtarget
AranidipineVoltage-dependent L-type calcium channel subunit alpha-1Ftarget
AranidipineVoltage-dependent L-type calcium channel subunit alpha-1Starget
AranidipineAlpha adrenergic receptortarget
AranidipineSerum albumincarrier
AranidipineAlpha-1-acid glycoprotein 1carrier
AranidipineCytochrome P450 3A4enzyme
AzelnidipineCytochrome P450 3A4enzyme
AzelnidipineVoltage-dependent L-type calcium channel subunit beta-1target
BarnidipineVoltage-dependent L-type calcium channel subunit alpha-1Ctarget
BarnidipineCytochrome P450 3A4enzyme
CaroverineCytochrome P450 3A4enzyme
CilnidipineVoltage-dependent N-type calcium channel subunit alpha-1Btarget
CilnidipineVoltage-dependent L-type calcium channeltarget
CilnidipineCytochrome P450 3A4enzyme
CinnarizineHistamine H1 receptortarget
CinnarizineDopamine D2 receptortarget
CinnarizineVoltage-dependent T-type calcium channel subunit alpha-1Htarget
CinnarizineCytochrome P450 2D6enzyme
CinnarizineCytochrome P450 2B6enzyme
CinnarizineCytochrome P450 2C9enzyme
CinnarizineCytochrome P450 1A1enzyme
CinnarizineCytochrome P450 1A2enzyme
CinnarizineCytochrome P450 2A6enzyme
CinnarizineVoltage-dependent L-type calcium channel subunit alpha-1Ctarget
CinnarizineVoltage-dependent L-type calcium channel subunit alpha-1Starget
CinnarizineVoltage-dependent L-type calcium channel subunit alpha-1Ftarget
CinnarizineVoltage-dependent L-type calcium channel subunit alpha-1Dtarget
CinnarizineVoltage-dependent T-type calcium channel subunit alpha-1Gtarget
CinnarizineVoltage-dependent T-type calcium channel subunit alpha-1Itarget
CinnarizineD(1) dopamine receptortarget
CinnarizineMuscarinic acetylcholine receptortarget
CinnarizineCytochrome P450 3A4enzyme
ClevidipineVoltage-dependent L-type calcium channel subunit alpha-1Ftarget
ClevidipineVoltage-dependent L-type calcium channel subunit alpha-1Starget
ClevidipineVoltage-dependent L-type calcium channel subunit alpha-1Dtarget
ClevidipineVoltage-dependent L-type calcium channel subunit alpha-1Ctarget
ClevidipineCytochrome P450 2C9enzyme
ClevidipineCytochrome P450 2D6enzyme
ClevidipineCytochrome P450 2E1enzyme
ClevidipineCytochrome P450 2C19enzyme
ClevidipineCytochrome P450 3A4enzyme
ClevidipineCholinesteraseenzyme
DarodipineCytochrome P450 3A4enzyme
EfonidipineVoltage-dependent T-type calcium channel subunit alpha-1Itarget
EfonidipineVoltage-dependent L-type calcium channel subunit alpha-1Ctarget
EfonidipineCytochrome P450 3A4enzyme
FendilineCytochrome P450 3A4enzyme
Fish oilDiacylglycerol O-acyltransferase 2target
Fish oilProstaglandin G/H synthase 2target
Fish oilFree fatty acid receptor 4target
Fish oilVoltage gated L-type calcium channeltarget
Fish oilSodium channel proteintarget
Fish oilFree radicalstarget
Fish oilNuclear factor NF-kappa-Btarget
Fish oilSterol regulatory element-binding protein 1target
Fish oilPeroxisome proliferator-activated receptor alphatarget
Fish oilPeroxisome proliferator-activated receptor gammatarget
Fish oilPeroxisome proliferator-activated receptor deltatarget
Fish oilCytochrome P450 3A4enzyme
GallopamilCytochrome P450 3A4enzyme
GallopamilP-glycoprotein 1transporter
LacidipineCytochrome P450 3A4enzyme
LacidipineSerum albumincarrier
LacidipineAlpha-1-acid glycoprotein 1carrier
LacidipineVoltage-dependent L-type calcium channeltarget
LercanidipineVoltage-dependent calcium channel gamma-1 subunittarget
LercanidipineCytochrome P450 3A4enzyme
LercanidipineCytochrome P450 3A5enzyme
LercanidipineCytochrome P450 3A7enzyme
LercanidipineCytochrome P450 2D6enzyme
Magnesium sulfateVoltage-dependent L-type calcium channeltarget
ManidipineVoltage-dependent L-type calcium channeltarget
ManidipineVoltage-dependent T-type calcium channeltarget
ManidipineCytochrome P450 2C9enzyme
ManidipineCytochrome P450 2D6enzyme
ManidipineCytochrome P450 1A1enzyme
ManidipineCytochrome P450 2B6enzyme
ManidipineCytochrome P450 2C19enzyme
ManidipineCytochrome P450 3A4enzyme
LevomentholTransient receptor potential cation channel subfamily A member 1target
LevomentholTransient receptor potential cation channel subfamily M member 8target
LevomentholTransient receptor potential cation channel subfamily V member 3target
LevomentholKappa-type opioid receptortarget
LevomentholVoltage-dependent L-type calcium channeltarget
LevomentholCytochrome P450 3A4enzyme
NaftopidilCytochrome P450 3A4enzyme
NiguldipineAlpha-1A adrenergic receptortarget
NiguldipineCytochrome P450 3A4enzyme
NiguldipineP-glycoprotein 1transporter
NiludipineCytochrome P450 3A4enzyme
NilvadipineCytochrome P450 3A4enzyme
NilvadipineCytochrome P450 2A6enzyme
NilvadipineCytochrome P450 2C19enzyme
NilvadipineCytochrome P450 2C8enzyme
NilvadipineCytochrome P450 2E1enzyme
NilvadipineVoltage-dependent L-type calcium channel subunit alpha-1Ctarget
NilvadipineVoltage-dependent calcium channel subunit alpha-2/delta-1target
NilvadipineVoltage-dependent L-type calcium channel subunit beta-2target
NilvadipineVoltage-dependent L-type calcium channel subunit alpha-1Dtarget
NilvadipineVoltage-dependent L-type calcium channel subunit alpha-1Starget
NilvadipineVoltage-dependent calcium channel subunit alpha-2/delta-3target
OtiloniumCytochrome P450 3A4enzyme
PinaveriumVoltage-dependent L-type calcium channel subunit alpha-1Starget
PinaveriumCytochrome P450 3A4enzyme
PregabalinExcitatory amino acid transporter 3transporter
PregabalinVoltage-dependent calcium channel subunit alpha-2/delta-1target
PregabalinLarge neutral amino acids transporter small subunit 1transporter
SeletracetamSynaptic vesicle glycoprotein 2Atarget
SeletracetamVoltage-dependent N-type calcium channel subunit alpha-1Btarget
SeletracetamGlycine receptor (alpha-1/beta)target
SeletracetamCytochrome P450 3A4enzyme
TerodilineCytochrome P450 3A4enzyme
TetrahydropalmatineDopamine D1 receptortarget
TetrahydropalmatineDopamine D2 receptortarget
TetrahydropalmatineCytochrome P450 3A4enzyme
ZiconotideVoltage-dependent N-type calcium channel subunit alpha-1Btarget
ZiconotideVoltage-dependent P/Q-type calcium channel subunit alpha-1Atarget
PrazosinAlpha-1A adrenergic receptortarget
PrazosinAlpha-1B adrenergic receptortarget
PrazosinAlpha-1D adrenergic receptortarget
PrazosinPotassium voltage-gated channel subfamily H member 2target
PrazosinAlpha-1-acid glycoprotein 1carrier
PrazosinSolute carrier family 22 member 1transporter
PrazosinSolute carrier family 22 member 3transporter
PrazosinP-glycoprotein 1transporter
PrazosinATP-binding cassette sub-family G member 2transporter
PrazosinAlpha-2A adrenergic receptortarget
PrazosinAlpha-2B adrenergic receptortarget
PrazosinAlpha-1 adrenergic receptorstarget
KetamineGlutamate receptor ionotropic, NMDA 3Atarget
KetamineNeurokinin 1 receptortarget
KetamineCytochrome P450 2B6enzyme
KetamineCytochrome P450 2C9enzyme
KetamineCytochrome P450 3A4enzyme
KetamineDopamine D2 receptortarget
KetamineProstaglandin G/H synthase 1enzyme
KetamineCytochrome P450 2C8enzyme
KetamineDelta-type opioid receptortarget
KetamineSodium-dependent noradrenaline transportertarget
KetamineKappa-type opioid receptortarget
KetamineMu-type opioid receptortarget
KetamineMuscarinic acetylcholine receptortarget
Ketamine5-hydroxytryptamine receptor 2target
Ketamine5-hydroxytryptamine receptor 1target
Ketamine5-hydroxytryptamine receptor 3Atarget
KetamineAlpha-7 nicotinic cholinergic receptor subunittarget
KetamineCholinesterasetarget
KetamineNitric oxide synthase, braintarget
PhentolamineAlpha-2A adrenergic receptortarget
PhentolamineAlpha-1A adrenergic receptortarget
PhentolamineAlpha-1B adrenergic receptortarget
PhentolamineAlpha-1D adrenergic receptortarget
FluoxetineSodium-dependent serotonin transportertarget
FluoxetineCytochrome P450 2C9enzyme
FluoxetineCytochrome P450 2D6enzyme
FluoxetineCYP2B proteinenzyme
FluoxetineCytochrome P450 1A2enzyme
FluoxetineCytochrome P450 3A4enzyme
FluoxetineCytochrome P450 2C19enzyme
FluoxetineP-glycoprotein 1transporter
FluoxetineCytochrome P450 2B6enzyme
FluoxetineCytochrome P450 3A5enzyme
FluoxetineSerum albumincarrier
FluoxetineAlpha-1-acid glycoprotein 1carrier
FluoxetinePotassium voltage-gated channel subfamily H member 2target
Fluoxetine5-hydroxytryptamine receptor 2Ctarget
FluoxetineCyclin-dependent kinases regulatory subunit 1target
FluoxetineNeuronal acetylcholine receptor subunit alpha-2target
FluoxetineNeuronal acetylcholine receptor subunit alpha-3target
FluoxetineNeuronal acetylcholine receptor subunit beta-4target
CitalopramSodium-dependent serotonin transportertarget
CitalopramCytochrome P450 2C19enzyme
CitalopramCytochrome P450 2D6enzyme
CitalopramCytochrome P450 3A4enzyme
CitalopramP-glycoprotein 1transporter
CitalopramCytochrome P450 1A2enzyme
CitalopramHistamine H1 receptortarget
LabetalolAlpha-1 adrenergic receptorstarget
LabetalolBeta-1 adrenergic receptortarget
LabetalolBeta-2 adrenergic receptortarget
LabetalolCytochrome P450 2D6enzyme
LabetalolCytochrome P450 2C19enzyme
LabetalolSerum albumincarrier
Labetalolalpha1-acid glycoproteincarrier
LabetalolATP-binding cassette sub-family B member 5transporter
LabetalolUDP-glucuronosyltransferase 1-1enzyme
LabetalolUDP-glucuronosyltransferase 2B7enzyme
LabetalolUDP-glucuronosyltransferase 1-9enzyme
DexverapamilP-glycoprotein 1target
DexverapamilCytochrome P450 3A4enzyme
DexverapamilP-glycoprotein 1transporter
FasudilcAMP-dependent protein kinase inhibitor alphatarget
FasudilcAMP-dependent protein kinase catalytic subunit alphatarget
FasudilRho-associated protein kinase 1target
FasudilRho-associated protein kinase 2target
IsosorbideApoptosis regulator Bcl-2target
IsosorbideBcl-2-like protein 1target
IsosorbideInduced myeloid leukemia cell differentiation protein Mcl-1target
AnagrelidecGMP-inhibited 3',5'-cyclic phosphodiesterase Atarget
AnagrelideCytochrome P450 1A2enzyme
DoxofyllinePhosphodiesterase 2A, cGMP-stimulatedtarget
DoxofyllineAdenosine receptor A2atarget
DoxofyllineBeta-2 adrenergic receptortarget
DoxofyllineCytochrome P450 1A2enzyme
Erythritol5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferasetarget