Opiate Partial Agonists

Name
Opiate Partial Agonists
Accession Number
DBCAT003704
Description

Not Available

Drugs
DrugDrug Description
ButorphanolAn opioid agonist-antagonist used to treat moderate to severe pain.
PentazocineAn analgesic used to treat moderate to severe pain.
NalbuphineAn opioid agonist-antagonist used to treat pain, for pre and postoperative analgesia, and for analgesia in labor and delivery.
BuprenorphineA partial opioid agonist used for management of severe pain that is not responsive to alternative treatments. Also used for maintenance treatment of opioid addiction.
Drugs & Drug Targets
DrugTargetType
ButorphanolKappa-type opioid receptortarget
ButorphanolMu-type opioid receptortarget
ButorphanolDelta-type opioid receptortarget
PentazocineMu-type opioid receptortarget
PentazocineKappa-type opioid receptortarget
PentazocineSigma non-opioid intracellular receptor 1target
PentazocineP-glycoprotein 1transporter
NalbuphineKappa-type opioid receptortarget
NalbuphineMu-type opioid receptortarget
NalbuphineDelta-type opioid receptortarget
BuprenorphineKappa-type opioid receptortarget
BuprenorphineMu-type opioid receptortarget
BuprenorphineCytochrome P450 3A4enzyme
BuprenorphineCytochrome P450 2D6enzyme
BuprenorphineP-glycoprotein 1transporter
BuprenorphineATP-binding cassette sub-family G member 2transporter
BuprenorphineCytochrome P450 2C9enzyme
BuprenorphineCytochrome P450 3A5enzyme
BuprenorphineCytochrome P450 2C8enzyme
BuprenorphineCytochrome P450 3A7enzyme
BuprenorphineDelta-type opioid receptortarget
BuprenorphineCytochrome P450 2C18enzyme
BuprenorphineCytochrome P450 2C19enzyme
BuprenorphineNociceptin receptortarget