DPP-IV Inhibitors
- Name
- DPP-IV Inhibitors
- Accession Number
- DBCAT002653 (DBCAT001315, DBCAT002433, DBCAT003757)
- Description
Compounds that suppress the degradation of INCRETINS by blocking the action of DIPEPTIDYL-PEPTIDASE IV. This helps to correct the defective INSULIN and GLUCAGON secretion characteristic of TYPE 2 DIABETES MELLITUS by stimulating insulin secretion and suppressing glucagon release.
- ATC Classification
- Drugs
Drug Drug Description Gemigliptin A dipeptidyl peptidase-4 (DPP-4) inhibitor used to manage hyperglycemia in patients with type 2 diabetes mellitus. Evogliptin Evogliptin has been used in trials studying the treatment and screening of Osteoporosis, Renal Impairment, Type 2 Diabetes Mellitus, Diabetes Mellitis Type 2, and Diabetes Mellitus, Type 2. Gosogliptin Gosogliptin has been used in trials studying the treatment of Renal Insufficiency, Chronic. Dutogliptin Dutogliptin has been investigated for the treatment of Diabetes Mellitus, Type II. Carmegliptin Carmegliptin has been used in trials studying the treatment of Diabetes Mellitus Type 2. Bisegliptin Investigated for use/treatment in diabetes mellitus type 2. AMG-222 Investigated for use/treatment in diabetes mellitus type 2. Teneligliptin Teneligliptin has been investigated for the treatment of Type 2 Diabetes Mellitus. Omarigliptin Omarigliptin has been used in trials studying the treatment of Type 2 Diabetes Mellitus and Chronic Renal Insufficiency. Anagliptin Anagliptin is under investigation for the treatment of LDL Cholesterol, Coronary Disease, Diabetes Mellitus, Glycosylated Hemoglobin, and Dipeptidyl-Peptidase 4 Inhibitors. Sitagliptin An oral dipeptidyl peptidase-4 (DPP-4) inhibitor used for the management of type 2 diabetes mellitus. Vildagliptin A once-daily dipeptidyl peptidase 4 (DPP-4) inhibitor used in the management of type 2 diabetes mellitus. Alogliptin A dipeptidyl peptidase-4 (DPP-4) inhibitor used to treat hyperglycemia in patients with type 2 diabetes mellitus. Saxagliptin An DPP-4 inhibitor used for the management of type 2 diabetes mellitus. Linagliptin A dipeptidyl peptidase-4 (DPP-4) inhibitor used to manage hyperglycemia in patients with type 2 diabetes mellitus. - Drugs & Drug Targets