|DB00244||Mesalazine||Mesalazine is indicated for the induction of remission in patients with active or mild to moderate acute exacerbations of ulcerative colitis and for the maintenance of remission of ulcerative colitis [FDA Label], [L5101]. Prescribing information for mesalazine in the UK also indicates the medication for the maintenance of remission of Crohn's ileo-colitis [L5101].|
|DB00328||Indometacin||Oral indometacin is indicated for symptomatic management of moderate to severe rheumatoid arthritis including acute flares of chronic disease, moderate to severe ankylosing spondylitis, moderate to severe osteoarthritis, acute painful shoulder (bursitis and/or tendinitis) and acute gouty arthritis.[A177871,Label]
Intravenous indometacin is indicated to induce closure of a hemodynamically significant patent ductus arteriosus in premature infants weighing between 500 and 1750 g when after 48 hours usual medical management (e.g., fluid restriction, diuretics, digitalis, respiratory support, etc.) is ineffective.[F4600]|
1) Symptomatic relief in rheumatoid arthritis
2) Symptomatic relief in osteoarthritis|
|DB00465||Ketorolac||Ketorolac is a Non-steroidal anti-inflammatory drug (NSAID) and has antipyretic, analgesic and anti-inflammatory properties. [A176131] It is indicated for short term management of acute pain that requires the caliber of pain management offered by opioids. [L6526] Clinicians may choose to initiate ketorolac to manage post-operative pain, spinal and soft tissue pain, rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, menstrual disorders and headaches among other ailments. [L6520] Regardless of the etiology of pain, patients should use the lowest possible dose, and avoid using ketorolac for an extended period of time (ideally ≤ 5 days).[L6526] A benefit of choosing ketorolac over other analgesics with similar potency is that that there does not appear to be a risk of dependence or tolerance with ketorolac use.[A176131] |
|DB00469||Tenoxicam||For the treatment of rheumatoid arthritis, osteoarthritis, backache, and pain.|
|DB00500||Tolmetin||For the relief of signs and symptoms of rheumatoid arthritis and osteoarthritis, including the treatment of acute flares long-term management. Also for treatment of juvenile rheumatoid arthritis.|
|DB00554||Piroxicam||For treatment of osteoarthritis and rheumatoid arthritis.|
|DB00573||Fenoprofen||For relief of the signs and symptoms of rheumatoid arthritis and osteoarthritis. Also for the relief of mild to moderate pain.|
|DB00749||Etodolac||For acute and long-term management of signs and symptoms of osteoarthritis and rheumatoid arthritis, as well as for the management of pain.|
|DB00861||Diflunisal||For symptomatic treatment of mild to moderate pain accompanied by inflammation (e.g. musculoskeletal trauma, post-dental extraction, post-episiotomy), osteoarthritis, and rheumatoid arthritis.|
|DB00870||Suprofen||Used as eye drops to inhibit the miosis (pupil constriction) that may occur during ocular surgery.|
|DB00939||Meclofenamic acid||For the relief of mild to moderate pain, for the treatment of primary dysmenorrhea and for the treatment of idiopathic heavy menstrual blood loss. Also for relief of the signs and symptoms of acute and chronic rheumatoid arthritis and osteoarthritis.|
|DB00945||Acetylsalicylic acid||**Pain, fever, and inflammation**
Acetylsalicylic acid (ASA), in the regular tablet form (immediate-release), is indicated to relieve pain, fever, and inflammation associated with many conditions, including the flu, the common cold, neck and back pain, dysmenorrhea, headache, tooth pain, sprains, fractures, myositis, neuralgia, synovitis, arthritis, bursitis, burns, and various injuries. It is also used for symptomatic pain relief after surgical and dental procedures [FDA label].
The _extra strength_ formulation of acetylsalicylic acid is also indicated for the management migraine pain with photophobia (sensitivity to light) and phonophobia (sensitivity to sound)[FDA label].
ASA is also indicated for various other purposes, due to its ability to inhibit platelet aggregation. These include:
Reducing the risk of cardiovascular death in suspected cases of myocardial infarction (MI) [FDA label].
Reducing the risk of a first non-fatal myocardial infarction in patients, and for reducing the risk of morbidity and mortality in cases of unstable angina and in those who have had a prior myocardial infarction [FDA label].
For reducing the risk of transient ischemic attacks (TIA) and to prevent atherothrombotic cerebral infarction (in conjunction with other treatments) [FDA label].
For the prevention of thromboembolism after hip replacement surgery [FDA label].
For decreasing platelet to platelet adhesion following carotid endarterectomy, aiding in the prevention of transient ischemic attacks (TIA) [FDA label].
Used for patients undergoing hemodialysis with a silicone rubber arteriovenous cannula inserted to prevent thrombosis at the insertion site [FDA Label].
**Important note regarding use of the extended-release formulation [F4405]**
In the setting of acute myocardial infarction, or before percutaneous interventions, the extended-release form of acetylsalicylic acid should not be used. Use immediate-release formulations in scenarios requiring rapid onset of action [Label, F4405]. The extended-release form is taken to decrease the incidence of mortality and myocardial infarction (MI) for individuals diagnosed with chronic coronary artery disease (CAD), including patients with previous myocardial infarction (MI) or unstable angina or with chronic stable angina. Additionally, the extended-release form is used to decrease the risk of death and recurrent episodes of stroke in patients with a history of stroke or TIA [F4405].
|DB00963||Bromfenac||For the treatment of postoperative inflammation in patients who have undergone cataract extraction.|
|DB01009||Ketoprofen||For symptomatic treatment of acute and chronic rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, primary dysmenorrhea and mild to moderate pain associated with musculotendinous trauma (sprains and strains), postoperative (including dental surgery) or postpartum pain.|
|DB01014||Balsalazide||For the treatment of mildly to moderately active ulcerative colitis.|
|DB00159||Icosapent||EPA can be used for lowering elevated triglycerides in those who are hyperglyceridemic. In addition, EPA may play a therapeutic role in patients with cystic fibrosis by reducing disease severity and may play a similar role in type 2 diabetics in slowing the progression of diabetic nephropathy.|
|DB00712||Flurbiprofen||Flurbiprofen tablets are indicated for the acute or long-term symptomatic treatment of rheumatoid arthritis, osteorarthritis and anklosing spondylitis. It may also be used to treat pain associated with dysmenorrhea and mild to moderate pain accompanied by inflammation (e.g. bursitis, tendonitis, soft tissue trauma). Topical ophthalmic formulations may be used pre-operatively to prevent intraoperative miosis. |
|DB00784||Mefenamic acid||For the treatment of rheumatoid arthritis, osteoarthritis, dysmenorrhea, and mild to moderate pain, inflammation, and fever.|
|DB01399||Salsalate||For relief of the signs and symptoms of rheumatoid arthritis, osteoarthritis and related rheumatic disorders.|
|DB00605||Sulindac||For acute or long-term use in the relief of signs and symptoms of osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, acute painful shoulder (acute subacromial bursitis/supraspinatus tendinitis), and acute gouty arthritis.|
|DB00936||Salicylic acid||Key additive in many skin-care products for the treatment of acne, psoriasis, callouses, corns, keratosis pilaris and warts.|
|DB00814||Meloxicam||For symptomatic treatment of arthritis and osteoarthritis.|
|DB00991||Oxaprozin||Used to relieve the inflammation, swelling, stiffness, and joint pain associated with rheumatoid arthritis and osteoarthritis.|
|DB01600||Tiaprofenic acid||Tiaprofenic acid is used to treat pain, especially arthritic pain.|
|DB01397||Magnesium salicylate||Magnesium salicylate is a common analgesic and non-steroidal anti-inflammatory drug (NSAID) used to treat mild to moderate muscular pain|
|DB06725||Lornoxicam||For the treatment of acute mild to moderate pain, as well as pain and inflammation of the joints caused by certain types of rheumatic diseases.|
|DB00821||Carprofen||For use as a pain reliever in the treatment of joint pain and post-surgical pain.|
|DB00812||Phenylbutazone||For the treatment of backache and ankylosing spondylitis|
|DB06802||Nepafenac||For the treatment of pain and inflammation associated with cataract surgery.|
|DB00795||Sulfasalazine||For the treatment of Crohn's disease and rheumatoid arthritis as a second-line agent.|
|DB01435||Antipyrine||Antipyrine is an analgesic often used to test effects of other drugs on liver enzymes..|
|DB01419||Antrafenine||Antrafenine is used as an anti-inflammatory and analgesic agent for the relief of mild to moderate pain.|
|DB01401||Choline magnesium trisalicylate||Choline magnesium trisalicylate is used to reduce pain and inflammation caused by conditions such as arthritis. This medication is also used to treat fever in adults.|
|DB09213||Dexibuprofen||For more information, refer to [ibuprofen].|
|DB06736||Aceclofenac||Aceclofenac is indicated for the relief of pain and inflammation in osteoarthritis, rheumatoid arthritis and ankylosing spondylitis. |
|DB09215||Droxicam||Droxicam is an NSAID previously used for the treatment of inflammation and rheumatoid arthritis [L1119].|
|DB11079||Trolamine salicylate||Indicated for the temporary relief of aches, and pains of muscles and joints associated with backache, lumbago, strains, bruises, sprains and arthritic or rheumatic pain, pain of tendons and ligaments [L1791].|
|DB13346||Bufexamac||Indicated for the treatment of various skin conditions, such as atopic eczema and other inflammatory dermatoses. |
|DB09214||Dexketoprofen||For short-term treatment of mild to moderate pain, including dysmenorrhoea, musculoskeletal pain and toothache [L1302]. |
|DB00586||Diclofenac||For the acute and chronic treatment of signs and symptoms of osteoarthritis and rheumatoid arthritis.|