Depsipeptides

Name
Depsipeptides
Accession Number
DBCAT003905
Description

Peptolides forming 16-membered macrolides, composed of two ester linkages, two amide linkages and seven asymmetric centers. They have been found in CYANOBACTERIA and are TUBULIN MODULATORS.

Drugs
DrugDrug Description
ValinomycinA cyclododecadepsipeptide ionophore antibiotic produced by Streptomyces fulvissimus and related to the enniatins. It is composed of 3 moles each of L-valine, D-alpha-hydroxyisovaleric acid, D-valine, and L-lactic acid linked alternately...
EchinomycinEchinomycin is a cytotoxic polypeptide quinoxaline antibiotic isolated from Streptomyces echinatus that binds to DNA and inhibits RNA synthesis.
Drugs & Drug Targets
DrugTargetType
ValinomycinBile salt export pumptransporter
ValinomycinP-glycoprotein 1transporter