COX-1 Inhibitors

Name

COX-1 Inhibitors

Accession Number

DBCAT003907 (DBCAT003903)

Description

Not Available

Drugs

Drug	Drug Description
Ibuprofen	An NSAID and non-selective COX inhibitor used to treat mild-moderate pain, fever, and inflammation.

Drugs & Drug Targets

Drug	Target	Type
Ibuprofen	Prostaglandin G/H synthase 1	target
Ibuprofen	Prostaglandin G/H synthase 2	target
Ibuprofen	Cytochrome P450 2C9	enzyme
Ibuprofen	Serum albumin	carrier
Ibuprofen	Multidrug resistance-associated protein 4	transporter
Ibuprofen	Multidrug resistance-associated protein 1	transporter
Ibuprofen	Solute carrier organic anion transporter family member 1A2	transporter
Ibuprofen	Solute carrier family 22 member 6	transporter
Ibuprofen	Solute carrier family 22 member 8	transporter
Ibuprofen	Solute carrier family 22 member 11	transporter
Ibuprofen	Solute carrier organic anion transporter family member 2B1	transporter
Ibuprofen	P-glycoprotein 1	transporter
Ibuprofen	UDP-glucuronosyltransferase 1-3	enzyme
Ibuprofen	UDP-glucuronosyltransferase 1-9	enzyme
Ibuprofen	UDP-glucuronosyltransferase 2B4	enzyme
Ibuprofen	UDP-glucuronosyltransferase 2B7	enzyme
Ibuprofen	Cytochrome P450 2C8	enzyme
Ibuprofen	Cytochrome P450 2C19	enzyme
Ibuprofen	Apoptosis regulator Bcl-2	target
Ibuprofen	Thrombomodulin	target
Ibuprofen	Fatty acid-binding protein, intestinal	target
Ibuprofen	Peroxisome proliferator-activated receptor gamma	target
Ibuprofen	Cystic fibrosis transmembrane conductance regulator	target
Ibuprofen	Peroxisome proliferator-activated receptor alpha	target
Ibuprofen	Platelet glycoprotein Ib alpha chain	target
Ibuprofen	Protein S100-A7	target
Ibuprofen	Alpha-methylacyl-CoA racemase	enzyme
Ibuprofen	Cytochrome P450 3A4	enzyme