Neprilysin Inhibitor

Accession Number

DBCAT004016

Description

Not Available

Drugs

Drug	Drug Description
Sacubitrilat	A metabolite of LCZ696 with neprilysin inhibitory activity.
Sacubitril	A neprilysin inhibitor used in combination with valsartan as an adjunct to reduce the risk of cardiovascular death and hospitalization for heart failure in patients with chronic heart failure (NYHA Class II-IV) and reduced ejection fraction.

Drugs & Drug Targets

Drug	Target	Type
Sacubitril	Neprilysin	target
Sacubitril	Solute carrier organic anion transporter family member 1B1	transporter
Sacubitril	Solute carrier organic anion transporter family member 1B3	transporter