Corticosteroid Hormone Receptor Agonists

Name
Corticosteroid Hormone Receptor Agonists
Accession Number
DBCAT004050
Description
Not Available
Drugs
DrugDrug Description
FlunisolideAn inhaled corticosteroid used as a prophylactic therapy in the maintenance treatment of asthma.
ClobetasolClobetasol is under investigation for the treatment of Scleroderma. Clobetasol has been investigated for the prevention of Psoriasis and Cutaneous Atrophy Due to Corticosteroids.
FluticasoneFluticasone's 2 esters are indicated as inhalers for the treatment and management of asthma by prophylaxis[FDA Label] as well as inflammatory and pruritic dermatoses . A DB00588 nasal spray is...
AlclometasoneA topical corticosteroid used to relieve the symptoms of corticosteroid-responsive dermatoses.
HalcinonideA corticosteroid used for the management and symptomatic relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses.
DesonideA topical corticosteroid used for the symptomatic treatment of inflammatory and pruritic manifestations of corticosteroid responsive dermatoses.
BudesonideA corticosteroid used to treat Crohn's disease, asthma, COPD, hay fever and allergies, and ulcerative colitis.
PrednicarbateA medium potency topical corticosteroid used to manage pruritus and inflammation associated with responsive skin conditions.
Beclomethasone dipropionateAn inhaled corticosteroid used as maintenance treatment in the prophylaxis of asthma attacks.
ClocortoloneA corticosteroid used to treat inflammatory and pruritic dermatoses of the scalp.
DiflorasoneA topical corticosteroid used to treat the symptoms of various inflammatory skin conditions that cause erythema, pruritus, and discomfort.
LoteprednolNot Annotated
HydrocortisoneA glucocorticoid used to treat corticosteroid-responsive dermatoses, endocrine disorders, immune conditions, and allergic disorders.
PrednisoloneA glucocorticoid used to treat adrenocortical insufficiency, inflammatory conditions, and some cancers.
UlobetasolA lipocortin corticosteroid used to treat inflammatory and pruritic corticosteroid-responsive dermatoses.
MometasoneA corticosteroid with no indications.
MethylprednisoloneA corticosteroid used to treat inflammation or immune reactions across a variety of organ systems, endocrine conditions, and neoplastic diseases.
TriamcinoloneA glucocorticoid used to treat a wide variety of inflammatory conditions of organ systems and tissues.
DexamethasoneA glucocorticoid available in various modes of administration that is used for the treatment of various inflammatory conditions, including bronchial asthma, as well as endocrine and rheumatic disorders.
DesoximetasoneA glucocorticoid used to treat inflammatory and pruritic corticosteroid-responsive dermatoses.
FluorometholoneAn ophthalmic corticosteroid used for the relief of inflammation located in both the palpebral and bulbar conjunctiva, the cornea, and the anterior segment of the globe of the eye.
BetamethasoneA systemic corticosteroid used to relieve inflammation in various conditions, including but not limited to allergic states, dermatologic disorders, gastrointestinal diseases, and hematological disorders.
AmcinonideA topical corticosteroid used in the treatment of inflammation and pruritus due to a variety of dermatoses.
RimexoloneA glucocorticoid used to treat inflammation of the eye.
FluocinonideA high potency corticosteroid commonly used topically for a number of inflammatory skin conditions.
FlurandrenolideA corticosteroid used to treat corticosteroid-responsive dermatoses.
Fluocinolone acetonideA corticosteroid used to treat skin conditions, eczematous otitis externa, diabetic macular edema, and non-infectious uveitis of the posterior segment of the eye.
MedrysoneA topical glucocorticoid applied ophthalmically for the treatment of various ocular inflammatory or allergic conditions.
DeflazacortA corticosteroid used to treat Duchenne muscular dystrophy.
CortisoneA naturally occurring glucocorticoid. It has been used in replacement therapy for adrenal insufficiency and as an anti-inflammatory agent. Cortisone itself is inactive. It is converted in the liver to...
PrednisoneA corticosteroid used to treat inflammation or immune-mediated reactions and to treat endocrine or neoplastic diseases.
Drugs & Drug Targets
DrugTargetType
FlunisolideCorticosteroid-binding globulincarrier
FlunisolideGlucocorticoid receptortarget
FlunisolideCytochrome P450 3A4enzyme
ClobetasolCytochrome P450 3A4enzyme
ClobetasolCytochrome P450 3A5enzyme
FluticasoneCytochrome P450 3A4enzyme
FluticasoneCytochrome P450 2C8enzyme
FluticasoneP-glycoprotein 1carrier
FluticasoneSolute carrier organic anion transporter family member 1B1carrier
FluticasoneP-glycoprotein 1transporter
FluticasoneSolute carrier organic anion transporter family member 1B1transporter
FluticasoneGlucocorticoid receptortarget
FluticasoneCorticosteroid-binding globulincarrier
FluticasoneCytochrome P450 3A5enzyme
FluticasoneCytochrome P450 3A7enzyme
FluticasoneProgesterone receptortarget
FluticasoneCytosolic phospholipase A2target
FluticasoneMineralocorticoid receptortarget
AlclometasoneCorticosteroid-binding globulincarrier
AlclometasoneGlucocorticoid receptortarget
AlclometasoneCytochrome P450 3A4enzyme
HalcinonideSmoothened homologtarget
HalcinonideCytochrome P450 3A4enzyme
DesonideGlucocorticoid receptortarget
DesonideCytochrome P450 3A4enzyme
BudesonideGlucocorticoid receptortarget
BudesonideCytochrome P450 3A4enzyme
BudesonideCytochrome P450 3A5enzyme
BudesonideBile salt export pumptransporter
BudesonideP-glycoprotein 1transporter
BudesonideAnnexin A1target
BudesonideCytochrome P450 3A Subfamilyenzyme
BudesonideCytochrome P450 2A6enzyme
BudesonideCytochrome P450 1B1enzyme
BudesonideCytochrome P450 2B6enzyme
BudesonideCytochrome P450 2C8enzyme
BudesonideCytochrome P450 2C9enzyme
BudesonideCytochrome P450 2C19enzyme
BudesonideCorticosteroid-binding globulincarrier
BudesonideSolute carrier organic anion transporter family member 1A2transporter
BudesonideSolute carrier family 22 member 8transporter
BudesonideSerum albumincarrier
PrednicarbateGlucocorticoid receptortarget
PrednicarbateCytochrome P450 3A4enzyme
Beclomethasone dipropionateCorticosteroid-binding globulincarrier
Beclomethasone dipropionateGlucocorticoid receptortarget
Beclomethasone dipropionateCytochrome P450 3A5enzyme
Beclomethasone dipropionateCytochrome P450 3A4enzyme
Beclomethasone dipropionateP-glycoprotein 1transporter
Beclomethasone dipropionateATP-binding cassette sub-family G member 2transporter
Beclomethasone dipropionateSolute carrier organic anion transporter family member 1B1transporter
Beclomethasone dipropionateSolute carrier organic anion transporter family member 1B3transporter
ClocortoloneGlucocorticoid receptortarget
DiflorasoneGlucocorticoid receptortarget
HydrocortisoneAnnexin A1target
HydrocortisoneGlucocorticoid receptortarget
HydrocortisoneSex hormone-binding globulincarrier
HydrocortisoneCytochrome P450 3A4enzyme
HydrocortisoneCytochrome P450 3A5enzyme
HydrocortisoneCytochrome P450 3A7enzyme
HydrocortisoneP-glycoprotein 1transporter
HydrocortisoneSolute carrier organic anion transporter family member 1A2transporter
HydrocortisoneCytochrome P450 11B1, mitochondrialenzyme
HydrocortisoneCytochrome P450 11B2, mitochondrialenzyme
HydrocortisoneCytochrome P450 2C8enzyme
HydrocortisoneCorticosteroid-binding globulincarrier
HydrocortisoneSolute carrier family 22 member 8transporter
Hydrocortisone3-oxo-5-beta-steroid 4-dehydrogenaseenzyme
Hydrocortisone3-oxo-5-alpha-steroid 4-dehydrogenase 2enzyme
HydrocortisoneCorticosteroid 11-beta-dehydrogenase isozyme 2enzyme
HydrocortisoneCorticosteroid 11-beta-dehydrogenase isozyme 1enzyme
HydrocortisoneCytochrome P450 2A6enzyme
HydrocortisoneCytochrome P450 1B1enzyme
HydrocortisoneCytochrome P450 2B6enzyme
HydrocortisoneCytochrome P450 2C9enzyme
HydrocortisoneCytochrome P450 2C19enzyme
PrednisoloneCorticosteroid-binding globulincarrier
PrednisoloneCytochrome P450 3A4enzyme
PrednisoloneGlucocorticoid receptortarget
PrednisoloneSolute carrier organic anion transporter family member 1A2transporter
PrednisoloneP-glycoprotein 1transporter
PrednisoloneSerum albumincarrier
UlobetasolCorticosteroid-binding globulincarrier
UlobetasolGlucocorticoid receptortarget
MometasoneGlucocorticoid receptortarget
MometasoneCytochrome P450 2C8enzyme
MometasoneProgesterone receptortarget
MometasoneCytochrome P450 3A4enzyme
MometasoneCytochrome P450 3A5enzyme
MethylprednisoloneGlucocorticoid receptortarget
MethylprednisoloneCytochrome P450 3A4enzyme
MethylprednisoloneP-glycoprotein 1transporter
MethylprednisoloneCytochrome P450 3A Subfamilyenzyme
MethylprednisoloneCytochrome P450 2A6enzyme
MethylprednisoloneCytochrome P450 1B1enzyme
MethylprednisoloneCytochrome P450 2B6enzyme
MethylprednisoloneCytochrome P450 2C8enzyme
MethylprednisoloneCytochrome P450 2C9enzyme
MethylprednisoloneCytochrome P450 2C19enzyme
MethylprednisoloneAnnexin A1target
Methylprednisolone20-ketosteroid reductase (20-hydroxysteroid dehydrogenase)enzyme
Methylprednisolone11beta-hydroxysteroid dehydrogenaseenzyme
MethylprednisoloneSerum albumincarrier
TriamcinoloneCorticosteroid-binding globulincarrier
TriamcinoloneGlucocorticoid receptortarget
TriamcinoloneCytochrome P450 3A4enzyme
TriamcinoloneProstaglandin G/H synthase 2enzyme
TriamcinoloneCholinesteraseenzyme
TriamcinoloneCytochrome P450 3A5enzyme
TriamcinoloneCytochrome P450 3A7enzyme
TriamcinoloneSerum albumincarrier
DexamethasoneGlucocorticoid receptortarget
DexamethasoneAnnexin A1target
DexamethasoneNitric oxide synthase, inducibletarget
DexamethasoneNuclear receptor subfamily 0 group B member 1target
DexamethasoneCytochrome P450 3A4enzyme
DexamethasoneCytochrome P450 3A5enzyme
DexamethasoneCytochrome P450 3A7enzyme
DexamethasoneBile salt export pumptransporter
DexamethasoneP-glycoprotein 1transporter
DexamethasoneCanalicular multispecific organic anion transporter 1transporter
DexamethasoneSolute carrier organic anion transporter family member 1A2transporter
DexamethasoneATP-binding cassette sub-family G member 2transporter
DexamethasoneSteroid 17-alpha-hydroxylase/17,20 lyaseenzyme
DexamethasoneCytochrome P450 1A1enzyme
DexamethasoneCytochrome P450 2A6enzyme
DexamethasoneCytochrome P450 2B6enzyme
DexamethasoneCytochrome P450 2C19enzyme
DexamethasoneCytochrome P450 2C8enzyme
DexamethasoneCytochrome P450 2E1enzyme
DexamethasoneCytochrome P450 3A43enzyme
DexamethasoneCytochrome P450 4A11enzyme
DexamethasoneNuclear receptor subfamily 1 group I member 2target
DexamethasoneCytochrome P450 11B1, mitochondrialenzyme
DexamethasoneSerum albumincarrier
DexamethasoneCorticosteroid 11-beta-dehydrogenase isozyme 2enzyme
DexamethasoneCorticosteroid 11-beta-dehydrogenase isozyme 1enzyme
DexamethasoneSolute carrier family 22 member 8transporter
DesoximetasoneGlucocorticoid receptortarget
FluorometholoneCorticosteroid-binding globulincarrier
FluorometholoneCytochrome P450 3A4enzyme
FluorometholoneGlucocorticoid receptortarget
FluorometholoneCytochrome P450 3A5enzyme
BetamethasoneGlucocorticoid receptortarget
BetamethasoneCytochrome P450 3A4enzyme
BetamethasoneP-glycoprotein 1transporter
BetamethasoneCytochrome P450 19A1enzyme
BetamethasoneCytochrome P450 3A5enzyme
BetamethasoneCytochrome P450 3A7enzyme
BetamethasoneCytochrome P450 2A6enzyme
BetamethasoneCytochrome P450 1B1enzyme
BetamethasoneCytochrome P450 2B6enzyme
BetamethasoneCytochrome P450 2C8enzyme
BetamethasoneCytochrome P450 2C9enzyme
BetamethasoneCytochrome P450 2C19enzyme
BetamethasoneSerum albumincarrier
BetamethasoneCorticosteroid-binding globulincarrier
AmcinonideGlucocorticoid receptortarget
AmcinonideAnnexin A1target
AmcinonideCytochrome P450 3A4enzyme
AmcinonideCytochrome P450 3A5enzyme
RimexoloneCorticosteroid-binding globulincarrier
RimexoloneGlucocorticoid receptortarget
RimexoloneCytochrome P450 3A4enzyme
RimexoloneCytochrome P450 3A5enzyme
FluocinonideCorticosteroid-binding globulincarrier
FluocinonideGlucocorticoid receptortarget
FluocinonideSmoothened homologtarget
FluocinonideCytochrome P450 3A4enzyme
FluocinonideCytochrome P450 3A5enzyme
FlurandrenolideCorticosteroid-binding globulincarrier
FlurandrenolideGlucocorticoid receptortarget
FlurandrenolideCytochrome P450 3A4enzyme
Fluocinolone acetonideCorticosteroid-binding globulincarrier
Fluocinolone acetonideGlucocorticoid receptortarget
Fluocinolone acetonideCytochrome P450 3A4enzyme
Fluocinolone acetonideAnnexin A1target
Fluocinolone acetonideAnnexin A2target
Fluocinolone acetonideAnnexin A3target
Fluocinolone acetonideAnnexin A4target
Fluocinolone acetonideAnnexin A5target
MedrysoneCorticosteroid-binding globulincarrier
MedrysoneGlucocorticoid receptortarget
MedrysoneCytochrome P450 3A4enzyme
MedrysoneCytochrome P450 3A5enzyme
MedrysoneSolute carrier organic anion transporter family member 1A2transporter
MedrysoneP-glycoprotein 1transporter
MedrysoneSolute carrier family 22 member 8transporter
DeflazacortCytochrome P450 3A4enzyme
DeflazacortGlucocorticoid receptortarget
DeflazacortCytochrome P450 3A5enzyme
CortisoneCytochrome P450 3A4enzyme
CortisoneCytochrome P450 3A5enzyme
PrednisoneGlucocorticoid receptortarget
PrednisoneCytochrome P450 3A4enzyme
PrednisoneP-glycoprotein 1transporter
PrednisoneSolute carrier organic anion transporter family member 1A2transporter
PrednisoneCytochrome P450 2C19enzyme
PrednisoneSerum albumincarrier
PrednisoneCytochrome P450 3A5enzyme
PrednisoneCorticosteroid-binding globulincarrier
PrednisoneCytochrome P450 3A Subfamilyenzyme
PrednisoneCytochrome P450 2A6enzyme
PrednisoneCytochrome P450 1B1enzyme
PrednisoneCytochrome P450 2B6enzyme
PrednisoneCytochrome P450 2C8enzyme
PrednisoneCytochrome P450 2C9enzyme
PrednisoneCorticosteroid 11-beta-dehydrogenase isozyme 1enzyme