Corticosteroid Hormone Receptor Agonists

DrugDrug NameDrug Description
DB00180FlunisolideAn inhaled corticosteroid used as a prophylactic therapy in the maintenance treatment of asthma.
DB11750ClobetasolClobetasol is under investigation for the treatment of Scleroderma. Clobetasol has been investigated for the prevention of Psoriasis and Cutaneous Atrophy Due to Corticosteroids.
DB13867FluticasoneFluticasone's 2 esters are indicated as inhalers for the treatment and management of asthma by prophylaxis[FDA Label] as well as inflammatory and pruritic dermatoses . A DB00588 nasal spray is...
DB00240AlclometasoneA topical corticosteroid used to relieve the symptoms of corticosteroid-responsive dermatoses.
DB06786HalcinonideA corticosteroid used for the management and symptomatic relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses.
DB01260DesonideA topical corticosteroid used for the symptomatic treatment of inflammatory and pruritic manifestations of corticosteroid responsive dermatoses.
DB01222BudesonideA corticosteroid used in the management of asthma, nasal polyposis, and rhinitis via inhalation, as well as mild to moderate active Crohn's disease and ulcerative colitis via ingestion.
DB01130PrednicarbateA medium potency topical corticosteroid used to manage pruritus and inflammation associated with responsive skin conditions.
DB00394Beclomethasone dipropionateAn inhaled corticosteroid used as maintenance treatment in the prophylaxis of asthma attacks.
DB00838ClocortoloneA corticosteroid used to treat inflammatory and pruritic dermatoses of the scalp.
DB00223DiflorasoneA topical corticosteroid used to treat the symptoms of various inflammatory skin conditions that cause erythema, pruritus, and discomfort.
DB00873LoteprednolNot Annotated
DB00741HydrocortisoneA glucocorticoid used to treat corticosteroid-responsive dermatoses, endocrine disorders, immune conditions, and allergic disorders.
DB00860PrednisoloneA glucocorticoid used to treat adrenocortical insufficiency, inflammatory conditions, and some cancers.
DB00596UlobetasolA lipocortin corticosteroid used to treat inflammatory and pruritic corticosteroid-responsive dermatoses.
DB00764MometasoneA corticosteroid used to treat asthma and allergic rhinitis.
DB00959MethylprednisoloneA corticosteroid used to treat inflammation or immune reactions across a variety of organ systems, endocrine conditions, and neoplastic diseases.
DB00620TriamcinoloneA glucocorticoid used to treat a wide variety of inflammatory conditions of organ systems and tissues.
DB01234DexamethasoneA glucocorticoid available in various modes of administration that is used for the treatment of various inflammatory conditions, including bronchial asthma, as well as endocrine and rheumatic disorders.
DB00547DesoximetasoneA glucocorticoid used to treat inflammatory and pruritic corticosteroid-responsive dermatoses.
DB00324FluorometholoneAn ophthalmic corticosteroid used for the relief of inflammation located in both the palpebral and bulbar conjunctiva, the cornea, and the anterior segment of the globe of the eye.
DB00443BetamethasoneA systemic corticosteroid used to relieve inflammation in various conditions, including but not limited to allergic states, dermatologic disorders, gastrointestinal diseases, and hematological disorders.
DB00288AmcinonideA topical corticosteroid used in the treatment of inflammation and pruritus due to a variety of dermatoses.
DB00896RimexoloneA glucocorticoid used to treat inflammation of the eye.
DB01047FluocinonideA high potency corticosteroid commonly used topically for a number of inflammatory skin conditions.
DB00846FlurandrenolideA corticosteroid used to treat corticosteroid-responsive dermatoses.
DB00591Fluocinolone acetonideA corticosteroid used to treat skin conditions, eczematous otitis externa, diabetic macular edema, and non-infectious uveitis of the posterior segment of the eye.
DB00253MedrysoneA topical glucocorticoid applied ophthalmically for the treatment of various ocular inflammatory or allergic conditions.
DB11921DeflazacortA corticosteroid used to treat Duchenne muscular dystrophy.
DB14681CortisoneA naturally occurring glucocorticoid. It has been used in replacement therapy for adrenal insufficiency and as an anti-inflammatory agent. Cortisone itself is inactive. It is converted in the liver to...
DB00635PrednisoneA corticosteroid used to treat inflammation or immune-mediated reactions and to treat endocrine or neoplastic diseases.
DrugDrug NameTargetType
DB00180FlunisolideCorticosteroid-binding globulincarrier
DB00180FlunisolideGlucocorticoid receptortarget
DB00180FlunisolideCytochrome P450 3A4enzyme
DB11750ClobetasolCytochrome P450 3A4enzyme
DB11750ClobetasolCytochrome P450 3A5enzyme
DB13867FluticasoneCytochrome P450 3A4enzyme
DB13867FluticasoneCytochrome P450 2C8enzyme
DB13867FluticasoneP-glycoprotein 1carrier
DB13867FluticasoneSolute carrier organic anion transporter family member 1B1carrier
DB13867FluticasoneP-glycoprotein 1transporter
DB13867FluticasoneSolute carrier organic anion transporter family member 1B1transporter
DB13867FluticasoneGlucocorticoid receptortarget
DB13867FluticasoneCorticosteroid-binding globulincarrier
DB13867FluticasoneCytochrome P450 3A5enzyme
DB13867FluticasoneCytochrome P450 3A7enzyme
DB13867FluticasoneProgesterone receptortarget
DB13867FluticasoneCytosolic phospholipase A2target
DB13867FluticasoneMineralocorticoid receptortarget
DB00240AlclometasoneCorticosteroid-binding globulincarrier
DB00240AlclometasoneGlucocorticoid receptortarget
DB00240AlclometasoneCytochrome P450 3A4enzyme
DB06786HalcinonideSmoothened homologtarget
DB06786HalcinonideCytochrome P450 3A4enzyme
DB01260DesonideGlucocorticoid receptortarget
DB01260DesonideCytochrome P450 3A4enzyme
DB01222BudesonideGlucocorticoid receptortarget
DB01222BudesonideCytochrome P450 3A4enzyme
DB01222BudesonideCytochrome P450 3A5enzyme
DB01222BudesonideBile salt export pumptransporter
DB01222BudesonideP-glycoprotein 1transporter
DB01130PrednicarbateGlucocorticoid receptortarget
DB01130PrednicarbateCytochrome P450 3A4enzyme
DB00394Beclomethasone dipropionateCorticosteroid-binding globulincarrier
DB00394Beclomethasone dipropionateGlucocorticoid receptortarget
DB00394Beclomethasone dipropionateCytochrome P450 3A5enzyme
DB00394Beclomethasone dipropionateCytochrome P450 3A4enzyme
DB00394Beclomethasone dipropionateP-glycoprotein 1transporter
DB00394Beclomethasone dipropionateATP-binding cassette sub-family G member 2transporter
DB00394Beclomethasone dipropionateSolute carrier organic anion transporter family member 1B1transporter
DB00394Beclomethasone dipropionateSolute carrier organic anion transporter family member 1B3transporter
DB00838ClocortoloneGlucocorticoid receptortarget
DB00223DiflorasoneGlucocorticoid receptortarget
DB00741HydrocortisoneAnnexin A1target
DB00741HydrocortisoneGlucocorticoid receptortarget
DB00741HydrocortisoneSex hormone-binding globulincarrier
DB00741HydrocortisoneCytochrome P450 3A4enzyme
DB00741HydrocortisoneCytochrome P450 3A5enzyme
DB00741HydrocortisoneCytochrome P450 3A7enzyme
DB00741HydrocortisoneP-glycoprotein 1transporter
DB00741HydrocortisoneSolute carrier organic anion transporter family member 1A2transporter
DB00741HydrocortisoneCytochrome P450 11B1, mitochondrialenzyme
DB00741HydrocortisoneCytochrome P450 11B2, mitochondrialenzyme
DB00741HydrocortisoneCytochrome P450 2C8enzyme
DB00741HydrocortisoneCorticosteroid-binding globulincarrier
DB00741HydrocortisoneSolute carrier family 22 member 8transporter
DB00741Hydrocortisone3-oxo-5-beta-steroid 4-dehydrogenaseenzyme
DB00741Hydrocortisone3-oxo-5-alpha-steroid 4-dehydrogenase 2enzyme
DB00741HydrocortisoneCorticosteroid 11-beta-dehydrogenase isozyme 2enzyme
DB00741HydrocortisoneCorticosteroid 11-beta-dehydrogenase isozyme 1enzyme
DB00741HydrocortisoneCytochrome P450 2A6enzyme
DB00741HydrocortisoneCytochrome P450 1B1enzyme
DB00741HydrocortisoneCytochrome P450 2B6enzyme
DB00741HydrocortisoneCytochrome P450 2C9enzyme
DB00741HydrocortisoneCytochrome P450 2C19enzyme
DB00741HydrocortisoneP-glycoprotein 1enzyme
DB00860PrednisoloneCorticosteroid-binding globulincarrier
DB00860PrednisoloneCytochrome P450 3A4enzyme
DB00860PrednisoloneGlucocorticoid receptortarget
DB00860PrednisoloneSolute carrier organic anion transporter family member 1A2transporter
DB00860PrednisoloneP-glycoprotein 1transporter
DB00860PrednisoloneSerum albumincarrier
DB00596UlobetasolCorticosteroid-binding globulincarrier
DB00596UlobetasolGlucocorticoid receptortarget
DB00764MometasoneGlucocorticoid receptortarget
DB00764MometasoneCytochrome P450 2C8enzyme
DB00764MometasoneProgesterone receptortarget
DB00764MometasoneCytochrome P450 3A4enzyme
DB00764MometasoneCytochrome P450 3A5enzyme
DB00959MethylprednisoloneGlucocorticoid receptortarget
DB00959MethylprednisoloneCytochrome P450 3A4enzyme
DB00959MethylprednisoloneP-glycoprotein 1transporter
DB00620TriamcinoloneCorticosteroid-binding globulincarrier
DB00620TriamcinoloneGlucocorticoid receptortarget
DB00620TriamcinoloneCytochrome P450 3A4enzyme
DB00620TriamcinoloneProstaglandin G/H synthase 2enzyme
DB00620TriamcinoloneCholinesteraseenzyme
DB00620TriamcinoloneCytochrome P450 3A5enzyme
DB00620TriamcinoloneCytochrome P450 3A7enzyme
DB00620TriamcinoloneSerum albumincarrier
DB01234DexamethasoneGlucocorticoid receptortarget
DB01234DexamethasoneAnnexin A1target
DB01234DexamethasoneNitric oxide synthase, inducibletarget
DB01234DexamethasoneNuclear receptor subfamily 0 group B member 1target
DB01234DexamethasoneCytochrome P450 3A4enzyme
DB01234DexamethasoneCytochrome P450 3A5enzyme
DB01234DexamethasoneCytochrome P450 3A7enzyme
DB01234DexamethasoneBile salt export pumptransporter
DB01234DexamethasoneP-glycoprotein 1transporter
DB01234DexamethasoneCanalicular multispecific organic anion transporter 1transporter
DB01234DexamethasoneSolute carrier organic anion transporter family member 1A2transporter
DB01234DexamethasoneATP-binding cassette sub-family G member 2transporter
DB01234DexamethasoneSteroid 17-alpha-hydroxylase/17,20 lyaseenzyme
DB01234DexamethasoneCytochrome P450 1A1enzyme
DB01234DexamethasoneCytochrome P450 2A6enzyme
DB01234DexamethasoneCytochrome P450 2B6enzyme
DB01234DexamethasoneCytochrome P450 2C19enzyme
DB01234DexamethasoneCytochrome P450 2C8enzyme
DB01234DexamethasoneCytochrome P450 2E1enzyme
DB01234DexamethasoneCytochrome P450 3A43enzyme
DB01234DexamethasoneCytochrome P450 4A11enzyme
DB01234DexamethasoneNuclear receptor subfamily 1 group I member 2target
DB01234DexamethasoneCytochrome P450 11B1, mitochondrialenzyme
DB00547DesoximetasoneGlucocorticoid receptortarget
DB00324FluorometholoneCorticosteroid-binding globulincarrier
DB00324FluorometholoneCytochrome P450 3A4enzyme
DB00324FluorometholoneGlucocorticoid receptortarget
DB00324FluorometholoneCytochrome P450 3A5enzyme
DB00443BetamethasoneGlucocorticoid receptortarget
DB00443BetamethasoneCytochrome P450 3A4enzyme
DB00443BetamethasoneP-glycoprotein 1transporter
DB00443BetamethasoneCytochrome P450 19A1enzyme
DB00443BetamethasoneCytochrome P450 3A5enzyme
DB00288AmcinonideGlucocorticoid receptortarget
DB00288AmcinonideAnnexin A1target
DB00288AmcinonideCytochrome P450 3A4enzyme
DB00288AmcinonideCytochrome P450 3A5enzyme
DB00896RimexoloneCorticosteroid-binding globulincarrier
DB00896RimexoloneGlucocorticoid receptortarget
DB00896RimexoloneCytochrome P450 3A4enzyme
DB00896RimexoloneCytochrome P450 3A5enzyme
DB01047FluocinonideCorticosteroid-binding globulincarrier
DB01047FluocinonideGlucocorticoid receptortarget
DB01047FluocinonideSmoothened homologtarget
DB01047FluocinonideCytochrome P450 3A4enzyme
DB01047FluocinonideCytochrome P450 3A5enzyme
DB00846FlurandrenolideCorticosteroid-binding globulincarrier
DB00846FlurandrenolideGlucocorticoid receptortarget
DB00846FlurandrenolideCytochrome P450 3A4enzyme
DB00591Fluocinolone acetonideCorticosteroid-binding globulincarrier
DB00591Fluocinolone acetonideGlucocorticoid receptortarget
DB00591Fluocinolone acetonideCytochrome P450 3A4enzyme
DB00591Fluocinolone acetonideAnnexin A1target
DB00591Fluocinolone acetonideAnnexin A2target
DB00591Fluocinolone acetonideAnnexin A3target
DB00591Fluocinolone acetonideAnnexin A4target
DB00591Fluocinolone acetonideAnnexin A5target
DB00253MedrysoneCorticosteroid-binding globulincarrier
DB00253MedrysoneGlucocorticoid receptortarget
DB00253MedrysoneCytochrome P450 3A4enzyme
DB00253MedrysoneCytochrome P450 3A5enzyme
DB11921DeflazacortCytochrome P450 3A4enzyme
DB11921DeflazacortGlucocorticoid receptortarget
DB11921DeflazacortCytochrome P450 3A5enzyme
DB14681CortisoneCytochrome P450 3A4enzyme
DB14681CortisoneCytochrome P450 3A5enzyme
DB00635PrednisoneGlucocorticoid receptortarget
DB00635PrednisoneCytochrome P450 3A4enzyme
DB00635PrednisoneP-glycoprotein 1transporter
DB00635PrednisoneSolute carrier organic anion transporter family member 1A2transporter
DB00635PrednisoneCytochrome P450 2C19enzyme
DB00635PrednisoneSerum albumincarrier
DB00635PrednisoneCytochrome P450 3A5enzyme
DB00635PrednisoneCorticosteroid-binding globulincarrier
DB00635PrednisoneCytochrome P450 3A Subfamilyenzyme
DB00635PrednisoneCytochrome P450 2A6enzyme
DB00635PrednisoneCytochrome P450 1B1enzyme
DB00635PrednisoneCytochrome P450 2B6enzyme
DB00635PrednisoneCytochrome P450 2C8enzyme
DB00635PrednisoneCytochrome P450 2C9enzyme
DB00635PrednisoneCorticosteroid 11-beta-dehydrogenase isozyme 1enzyme