Local Anesthesia

DrugDrug NameDrug Description
DB00297BupivacaineA local anesthetic used in a wide variety of superficial and invasive procedures.
DB00750PrilocaineA local anesthetic used in dental procedures.
DB00296RopivacaineAn analgesic drug used for local or regional anesthesia for surgery and short-term management of pain.
DB00807ProparacaineA topical anesthetic used for ophthalmic practice.
DB01161ChloroprocaineA local anesthetic agent indicated for intrathecal injection in adults for the production of subarachnoid block, or spinal anesthesia.
DB00961MepivacaineA local anesthetic used for local or regional analgesia or anesthesia.
DB00281LidocaineA local anesthetic used in a wide variety of superficial and invasive procedures.
DB09085TetracaineA local anaesthetic agent used to induce local analgesia in the eyes and skin during medical procedures.
DB09009ArticaineA local anesthetic used for inducing local, infiltrative, or conductive anesthesia in both simple and complex dental procedures.
DrugDrug NameTargetType
DB00297BupivacaineSodium channel protein type 10 subunit alphatarget
DB00297BupivacaineProstaglandin E2 receptor EP1 subtypetarget
DB00297BupivacaineCytochrome P450 3A4enzyme
DB00297BupivacaineCytochrome P450 2C19enzyme
DB00297BupivacaineCytochrome P450 2D6enzyme
DB00750PrilocaineSodium channel protein type 5 subunit alphatarget
DB00296RopivacaineSodium channel protein type 10 subunit alphatarget
DB00296RopivacaineCytochrome P450 1A2enzyme
DB00296RopivacaineCytochrome P450 2B6enzyme
DB00296RopivacaineCytochrome P450 3A4enzyme
DB00807ProparacaineSodium channel protein type 10 subunit alphatarget
DB01161ChloroprocaineSodium channel protein type 10 subunit alphatarget
DB01161ChloroprocaineNeuronal acetylcholine receptor subunit alpha-10target
DB01161ChloroprocaineSodium-dependent dopamine transportertarget
DB01161ChloroprocaineGlutamate receptor ionotropic, NMDA 3Atarget
DB01161Chloroprocaine5-hydroxytryptamine receptor 3Atarget
DB01161ChloroprocaineCholinesteraseenzyme
DB00961MepivacaineSodium channel protein type 10 subunit alphatarget
DB00281LidocaineSodium channel protein type 5 subunit alphatarget
DB00281LidocaineSodium channel protein type 10 subunit alphatarget
DB00281LidocaineEpidermal growth factor receptortarget
DB00281LidocaineSodium channel protein type 9 subunit alphatarget
DB00281LidocaineCytochrome P450 1A2enzyme
DB00281LidocaineCytochrome P450 2D6enzyme
DB00281LidocaineCytochrome P450 3A4enzyme
DB00281LidocaineCytochrome P450 3A5enzyme
DB00281LidocaineCytochrome P450 3A7enzyme
DB00281LidocaineSolute carrier family 22 member 5transporter
DB00281LidocaineP-glycoprotein 1transporter
DB00281LidocaineCytochrome P450 2A6enzyme
DB00281LidocaineCytochrome P450 2B6enzyme
DB00281LidocaineCytochrome P450 2C8enzyme
DB00281LidocaineCytochrome P450 2C9enzyme
DB00281LidocaineSodium channel protein type 4 subunit alphatarget
DB00281LidocaineAlpha-1-acid glycoprotein 1target
DB00281LidocaineAlpha-1-acid glycoprotein 2target
DB09085TetracaineRyanodine receptor 1target
DB09085TetracaineRyanodine receptor 2target
DB09085TetracaineVoltage-gated sodium channel alpha subunittarget