Adrenergic beta2-Antagonists

Accession Number

DBCAT004124

Description

Not Available

Drugs

Drug	Drug Description
Carvedilol	A non selective beta-adrenergic antagonist used to treat mild to severe chronic heart failure, hypertension, and left ventricular dysfunction following myocardial infarction in clinically stable patients.

Drugs & Drug Targets

Drug	Target	Type
Carvedilol	Alpha-1A adrenergic receptor	target
Carvedilol	Beta-1 adrenergic receptor	target
Carvedilol	NADH dehydrogenase [ubiquinone] 1 subunit C2	target
Carvedilol	Beta-2 adrenergic receptor	target
Carvedilol	Vascular endothelial growth factor A	target
Carvedilol	Natriuretic peptides B	target
Carvedilol	Gap junction alpha-1 protein	target
Carvedilol	Potassium voltage-gated channel subfamily H member 2	target
Carvedilol	Vascular cell adhesion protein 1	target
Carvedilol	Cytochrome P450 2C9	enzyme
Carvedilol	Cytochrome P450 2D6	enzyme
Carvedilol	Xanthine dehydrogenase/oxidase	enzyme
Carvedilol	P-glycoprotein 1	transporter
Carvedilol	Cytochrome P450 1A2	enzyme
Carvedilol	Cytochrome P450 3A4	enzyme
Carvedilol	Cytochrome P450 1A1	enzyme
Carvedilol	Cytochrome P450 2E1	enzyme
Carvedilol	Alpha-1D adrenergic receptor	target
Carvedilol	Alpha-1B adrenergic receptor	target
Carvedilol	Alpha-2C adrenergic receptor	target
Carvedilol	Alpha-2B adrenergic receptor	target
Carvedilol	Alpha-2A adrenergic receptor	target
Carvedilol	E-selectin	target
Carvedilol	Hypoxia-inducible factor 1-alpha	target
Carvedilol	Inward rectifier potassium channel 4	target
Carvedilol	UDP-glucuronosyltransferase 1-1	enzyme
Carvedilol	Serum albumin	carrier
Carvedilol	UDP-glucuronosyltransferase 2B4	enzyme
Carvedilol	UDP-glucuronosyltransferase 2B7	enzyme
Carvedilol	Inward rectifier potassium channel 2	target
Carvedilol	Alpha-1 adrenergic receptors	target