Cytochrome P-450 CYP2C19 inhibitors (strength unknown)

Inhibitors of CYP2C19 enzyme with unknown strength of inhibition.
DrugDrug NameDrug Description
DB01171MoclobemideA monoamine oxidase inhibitor used in the treatment of major depressive disorder and bipolar disorder.
DB00622NicardipineA calcium channel blocker used for the short-term treatment of hypertension and chronic stable angina.
DB00328IndomethacinA nonsteroidal anti-inflammatory (NSAID) used for symptomatic management of chronic musculoskeletal pain conditions and to induce closure of a hemodynamically significant patent ductus arteriosus in premature infants.
DB00396ProgesteroneA hormone used for a variety of functions, including contraception, control of abnormal uterine bleeding, maintenance of pregnancy, and prevention of endometrial hyperplasia.
DB00949FelbamateAn anticonvulsant used to treat severe epilepsy.
DB01129RabeprazoleA proton pump inhibitor used to help gastrointestinal ulcers heal, to treat symptoms of gastroesophageal reflux disease (GERD), to eradicate Helicobacter pylori, and to treat hypersecretory conditions such as Zollinger-Ellison Syndrome.
DB00197TroglitazoneFor the treatment of Type II diabetes mellitus. It is used alone or in combination with a sulfonylurea, metformin, or insulin as an adjunct to diet and exercise.
DB00321AmitriptylineA tricyclic antidepressant indicated in the treatment of depressive illness, either endogenous or psychotic, and to relieve depression associated anxiety.
DB00458ImipramineA tricyclic antidepressant indicated for the treatment of depression and to reduce childhood enuresis.
DB00503RitonavirAn HIV protease inhibitor used in combination with other antivirals in the treatment of HIV infection.
DB00532MephenytoinA phenylhydantoin used to treat refractory partial epilepsy.
DB00752TranylcypromineA monoamine oxidase inhibitor used to treat major depressive disorder.
DB00776OxcarbazepineAn anti-epileptic used in the treatment of partial-onset seizures.
DB01026KetoconazoleA broad spectrum antifungal used to treat seborrheic dermatitis and fungal skin infections.
DB01041ThalidomideA medication used to treat newly diagnosed multiple myeloma and erythema nodosum leprosum.
DB01424AminophenazoneFormerly widely used as an antipyretic and analgesic in rheumatism, neuritis, and common colds. Currently used to measure total body water.
DB01095FluvastatinAn HMG-CoA reductase inhibitor used to lower lipid levels and reduce the risk of cardiovascular disease including myocardial infarction and stroke.
DB00468QuinineAn alkaloid used to treat uncomplicated Plasmodium falciparum malaria.
DB00682WarfarinA vitamin K antagonist used to treat venous thromboembolism, pulmonary embolism, thromboembolism with atrial fibrillation, thromboembolism with cardiac valve replacement, and thromboembolic events post myocardial infarction.
DB00829DiazepamA long-acting benzodiazepine with rapid onset commonly used to treat panic disorders, severe anxiety, alcohol withdrawal, and seizures.
DB00501CimetidineA histamine H2 receptor antagonist used to manage GERD, peptic ulcer disease, and indigestion.
DB01032ProbenecidA medication used to treat gouty arthritis, tophaceous gout, and hyperuricemia.
DB00564CarbamazepineAn anticonvulsant used to treat various types of seizures and pain resulting from trigeminal neuralgia.
DB00921BuprenorphineA partial opioid agonist used for management of severe pain that is not responsive to alternative treatments. Also used for maintenance treatment of opioid addiction.
DB00091CyclosporineA steroid-sparing immunosuppressant used in organ and bone marrow transplants as well as inflammatory conditions such as ulcerative colitis, rheumatoid arthritis, and atopic dermatitis.
DB01093Dimethyl sulfoxideA reversible mitogen-activated extracellular signal-regulated kinase-1 (MEK1) and MEK2 inhibitor used to treat certain types of melanoma, metastatic non-small cell lung cancer, and locally advanced or metastatic anaplastic thyroid cancer.
DB00678LosartanAn angiotensin receptor blocker used to treat hypertension and diabetic nephropathy, and is used to reduce the risk of stroke.
DB00780PhenelzineA monoamine oxidase inhibitor used to treat atypical, nonendogenous, or neurotic depression.
DB00259SulfanilamideA sulfonamide anti-infective used to treat vulvovaginal candidiasis caused by Candida albicans.
DB00966TelmisartanAn ARB used to treat hypertension, diabetic nephropathy, and congestive heart failure.
DB00763MethimazoleA thionamide antithyroid agent that inhibits the actions of thyroid peroxidase, leading to a reduction in thyroid hormone synthesis and amelioration of hyperthyroidism.
DB00313Valproic acidAn anticonvulsant used to control complex partial seizures and both simple and complex absence seizures.
DB00398SorafenibA kinase inhibitor used in the treatment of unresectable liver carcinoma and advanced renal carcinoma.
DB01128BicalutamideAn androgen receptor inhibitor used to treat Stage D2 metastatic carcinoma of the prostate.
DB04920ClevidipineA dihydropyridine L-type calcium channel blocker used to lower blood pressure when oral antihypertensive therapy is not feasible or not desirable.
DB08828VismodegibA hedgehog pathway inhibitor used to treat patients with locally advanced or metastatic basal cell carcinoma.
DB09054IdelalisibAn antineoplastic kinase inhibitor used to treat chronic lymphocytic leukemia (CLL), relapsed follicular B-cell non-Hodgkin lymphoma (FL), and relapsed small lymphocytic lymphoma (SLL).
DB01685TopiroxostatIndicated for the treatment of gout and hyperurcemia in Japan.
DB09198LobeglitazoneLobeglitazone was approved by the Ministry of Food and Drug Safety (South Korea) in 2013, and is being monitored by postmarketing surveillance until 2019. Lobeglitazone is not approved for use...
DB09167DosulepinIndicated in the treatment of symptoms of depressive illness, especially where an anti-anxiety effect is required.
DB12319BenzbromaroneBenzbromarone has been used in trials studying the basic science and treatment of Heart Failure, Hyperuricemia, Chronic Kidney Disease, Abnormal Renal Function, and Gout and Asymptomatic Hyperuricemia.
DB13874EnasidenibAn isocitrate dehydrogenase-2 inhibitor used to treat relapsed or refractory acute myeloid leukemia with an isocitrate dehydrogenase-2 mutation.
DB13941PiperaquineFor the treatment of uncomplicated Plasmodium falciparum infection in adults, children, and infants aged 6 months and up weighing over 5 kg [FDA Label]. Used in combination with DB11638.
DB11633IsavuconazoleIndicated for patients 18 years of age and older for the treatment of invasive aspergillosis [FDA Label]. Indicated for patients 18 years of age and older for the treatment of...
DB06654SafinamideA MAO-B inhibitor used as an add-on treatment to levodopa/carbidopa for Parkinson's disease during "off" episodes.
DB09078LenvatinibA receptor tyrosine kinase inhibitor used for the treatment of metastatic thyroid cancer, advanced renal cell carcinoma in combination with everolimus, and unresectable hepatocellular carcinoma.
DB05246MethsuximideA succinimide anticonvulsant that increases the seizure threshold. Primarily used for childhood absence seizures. Functions by suppressing paroxysmal spike-and-wave patterns associated with lapses of consciousness in absence seizures.
DB06414EtravirineA non-nucleoside reverse transcriptase inhibitor (NNRTI) used in the treatment of HIV-1 infections in combination with other antiretroviral agents.
DB00745ModafinilA stimulant used to improve wakefulness in patients with sleep apnea, narcolepsy, or shift work disorder.
DB01118AmiodaroneA class III antiarrhythmic indicated for the treatment of recurrent hemodynamically unstable ventricular tachycardia and recurrent ventricular fibrillation.
DB00972AzelastineA histamine H1-receptor antagonist used intranasally to treat allergic and vasomotor rhinitis and in an ophthalmic solution to treat allergic conjunctivitis.
DB06268SitaxentanInvestigated for use/treatment in pulmonary hypertension, connective tissue diseases, hypertension, and congestive heart failure.
DB00363ClozapineAn antipsychotic drug used in treatment resistant schizophrenia and to decrease suicide risk in schizophrenic patients.
DB00701AmprenavirA protease inhibitor used to treat HIV infection.
DB01110MiconazoleAn antifungal used to treat fungal infections affecting the vagina, mouth and skin.
DB00317GefitinibA tyrosine kinase inhibitor used as first-line therapy to treat non-small cell lung carcinoma (NSCLC) that meets certain genetic mutation criteria.
DB06731SeproxetineSeproxetine is also known as (S)-norfluoxetine. It is a selective serotonin reuptake inhibitor (SSRI). It is an active metabolite of fluoxetine. Seproxetine was being investigated by Eli Lilly as an...
DB11753RifamycinAn antibacterial used to treat traveler's diarrhea.
DB00196FluconazoleA triazole antifungal used to treat various fungal infections including candidiasis.
DB12245TriclabendazoleAn anthelmintic drug used to treat fascioliasis.
DB12015AlpelisibAlpelisib is indicated in combination with fulvestrant to treat postmenopausal women, and men, with advanced or metastatic breast cancer.[Label] This cancer must be hormone receptor (HR)-positive, human epidermal growth factor...
DB12474LynestrenolLynestrenol has been used in trials studying the basic science of Transsexualism and Gender Dysphoria.
DB00977EthinylestradiolAn estradiol used as a contraceptive.
DB06730GestodeneGestodene is a progestogen hormonal contraceptive. Products containing gestoden include Meliane, which contains 20 mcg of ethinylestradiol and 75 mcg of gestodene; and Gynera, which contains 30 mcg of ethinylestradiol...
DB00715ParoxetineA selective serotonin reuptake inhibitor used to treat major depressive disorder, panic disorder, OCD, social phobia, generalized anxiety disorder, the vasomotor symptoms of menopause, and premenstrual dysphoric disorder.
DB00673AprepitantA substance P/neurokinin 1 receptor antagonist used to treat nausea and vomiting caused by chemotherapy and surgery.
DB06442AvasimibeInvestigated for use/treatment in peripheral vascular disease.
DB14635Curcumin sulfateNo approved therapeutic indications.
DB14575EslicarbazepineAdjunctive Therapy for Adults with Partial-Onset Seizures
DB15444ElexacaftorElexacaftor, in combination with ivacaftor and tezacaftor as the combination product TrikaftaTM, is indicated for the treatment of cystic fibrosis (CF) in patients 12 years of age and older who...
DrugDrug NameTargetType
DB01171MoclobemideAmine oxidase [flavin-containing] Atarget
DB01171MoclobemideCytochrome P450 2C19enzyme
DB01171MoclobemideCytochrome P450 2D6enzyme
DB01171MoclobemideAmine oxidase [flavin-containing] Aenzyme
DB01171MoclobemideAmine oxidase [flavin-containing] Benzyme
DB01171MoclobemideCytochrome P450 2C9enzyme
DB01171MoclobemideMonoamine oxidasetarget
DB01171MoclobemideAmine oxidase [flavin-containing] Btarget
DB00622NicardipineVoltage-dependent L-type calcium channel subunit alpha-1Ctarget
DB00622NicardipineCytochrome P450 3A4enzyme
DB00622NicardipineCytochrome P450 2C19enzyme
DB00622NicardipineCytochrome P450 2C8enzyme
DB00622NicardipineCytochrome P450 2D6enzyme
DB00622NicardipineCalcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1Btarget
DB00622NicardipineCalcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1Atarget
DB00622NicardipineAlpha-1A adrenergic receptortarget
DB00622NicardipineAlpha-1D adrenergic receptortarget
DB00622NicardipineAlpha-1B adrenergic receptortarget
DB00622NicardipineMuscarinic acetylcholine receptor M1target
DB00622NicardipineMuscarinic acetylcholine receptor M2target
DB00622NicardipineMuscarinic acetylcholine receptor M3target
DB00622NicardipineMuscarinic acetylcholine receptor M4target
DB00622NicardipineMuscarinic acetylcholine receptor M5target
DB00622NicardipineVoltage-dependent calcium channel subunit alpha-2/delta-1target
DB00622NicardipineVoltage-dependent L-type calcium channel subunit beta-2target
DB00622NicardipineVoltage-dependent L-type calcium channel subunit alpha-1Dtarget
DB00622NicardipineCalmodulintarget
DB00622NicardipineP-glycoprotein 1transporter
DB00622NicardipineCytochrome P450 2B6enzyme
DB00622NicardipineCytochrome P450 2E1enzyme
DB00622NicardipineCytochrome P450 3A5enzyme
DB00622NicardipineSolute carrier organic anion transporter family member 1B1transporter
DB00622NicardipineBile salt export pumptransporter
DB00622NicardipineCytochrome P450 2C9enzyme
DB00328IndomethacinProstaglandin G/H synthase 1target
DB00328IndomethacinProstaglandin G/H synthase 2target
DB00328IndomethacinCytochrome P450 2C19enzyme
DB00328IndomethacinUDP-glucuronosyltransferase 1-9enzyme
DB00328IndomethacinPhospholipase A2, membrane associatedtarget
DB00328IndomethacinProstaglandin reductase 2target
DB00328IndomethacinLactoylglutathione lyasetarget
DB00328IndomethacinProstaglandin D2 receptor 2target
DB00328IndomethacinPeroxisome proliferator-activated receptor gammatarget
DB00328IndomethacinSerum albumincarrier
DB00328IndomethacinCanalicular multispecific organic anion transporter 2transporter
DB00328IndomethacinMultidrug resistance-associated protein 4transporter
DB00328IndomethacinMultidrug resistance-associated protein 6transporter
DB00328IndomethacinP-glycoprotein 1transporter
DB00328IndomethacinMultidrug resistance-associated protein 1transporter
DB00328IndomethacinSolute carrier organic anion transporter family member 1A2transporter
DB00328IndomethacinSolute carrier family 22 member 6transporter
DB00328IndomethacinSolute carrier family 22 member 8transporter
DB00328IndomethacinCanalicular multispecific organic anion transporter 1transporter
DB00328IndomethacinATP-binding cassette sub-family C member 11transporter
DB00328IndomethacinSolute carrier family 22 member 11transporter
DB00328IndomethacinSodium/bile acid cotransportertransporter
DB00328IndomethacinSolute carrier family 22 member 7transporter
DB00328IndomethacinCytochrome P450 2C9enzyme
DB00328IndomethacinUDP-glucuronosyltransferase 1-1enzyme
DB00328IndomethacinLiver carboxylesterase 1enzyme
DB00328IndomethacinUDP-glucuronosyltransferase 2B7enzyme
DB00328IndomethacinPeroxisome proliferator-activated receptor alphatarget
DB00328IndomethacinAldo-keto reductase family 1 member C3target
DB00328IndomethacinSolute carrier organic anion transporter family member 1B1transporter
DB00328IndomethacinBile salt export pumptransporter
DB00396ProgesteroneProgesterone receptortarget
DB00396ProgesteroneEstrogen receptor alphatarget
DB00396ProgesteroneSteroid 17-alpha-hydroxylase/17,20 lyasetarget
DB00396ProgesteroneCytochrome P450 2C19enzyme
DB00396ProgesteroneCytochrome P450 2C9enzyme
DB00396ProgesteroneCytochrome P450 3A4enzyme
DB00396ProgesteroneCytochrome P450 3A5enzyme
DB00396ProgesteroneCytochrome P450 3A7enzyme
DB00396ProgesteroneP-glycoprotein 1transporter
DB00396ProgesteroneSolute carrier family 22 member 2transporter
DB00396ProgesteroneSolute carrier family 22 member 1transporter
DB00396ProgesteroneSolute carrier family 22 member 3transporter
DB00396ProgesteroneBile salt export pumptransporter
DB00396ProgesteroneMultidrug resistance-associated protein 1transporter
DB00396ProgesteroneSodium/bile acid cotransportertransporter
DB00396ProgesteroneSteroid 17-alpha-hydroxylase/17,20 lyaseenzyme
DB00396ProgesteroneCytochrome P450 1A1enzyme
DB00396ProgesteroneCytochrome P450 1B1enzyme
DB00396ProgesteroneCytochrome P450 2A6enzyme
DB00396ProgesteroneCytochrome P450 2D6enzyme
DB00396ProgesteroneMineralocorticoid receptortarget
DB00396ProgesteroneKappa-type opioid receptortarget
DB00396ProgesteroneAlpha-1-acid glycoprotein 1target
DB00396ProgesteroneGlucocorticoid receptortarget
DB00396ProgesteroneAndrogen receptortarget
DB00396ProgesteroneSex hormone-binding globulintarget
DB00396ProgesteroneSolute carrier organic anion transporter family member 1B1transporter
DB00396ProgesteroneATP-binding cassette sub-family G member 2transporter
DB00396ProgesteroneEstrogen receptor betatarget
DB00396ProgesteroneSolute carrier organic anion transporter family member 1B3transporter
DB00949FelbamateGlutamate receptor ionotropic, NMDA 3Atarget
DB00949FelbamateGlutamate receptor ionotropic, NMDA 2Btarget
DB00949FelbamateGlutamate receptor ionotropic, NMDA 2Atarget
DB00949FelbamateCytochrome P450 2C19enzyme
DB00949FelbamateCytochrome P450 3A4enzyme
DB00949FelbamateCytochrome P450 2E1enzyme
DB00949FelbamateCytochrome P450 2C9enzyme
DB01129RabeprazolePotassium-transporting ATPase alpha chain 1target
DB01129RabeprazoleCytochrome P450 3A4enzyme
DB01129RabeprazoleCytochrome P450 2C19enzyme
DB01129RabeprazoleATP-binding cassette sub-family G member 2transporter
DB01129RabeprazoleCytochrome P450 1A1enzyme
DB01129RabeprazoleCytochrome P450 1A2enzyme
DB01129RabeprazoleCytochrome P450 2C9enzyme
DB01129RabeprazoleCytochrome P450 2D6enzyme
DB01129RabeprazoleCytochrome P450 2C8enzyme
DB00197TroglitazonePeroxisome proliferator-activated receptor gammatarget
DB00197TroglitazoneLong-chain-fatty-acid--CoA ligase 4target
DB00197TroglitazonePlasminogen activator inhibitor 1target
DB00197TroglitazoneEquilibrative nucleoside transporter 1target
DB00197TroglitazoneCytochrome P450 3A4enzyme
DB00197TroglitazoneCytochrome P450 2C19enzyme
DB00197TroglitazoneUDP-glucuronosyltransferase 1-1enzyme
DB00197TroglitazoneCytochrome P450 2C8enzyme
DB00197TroglitazoneBile salt export pumptransporter
DB00197TroglitazoneSolute carrier organic anion transporter family member 1B1transporter
DB00197TroglitazoneEstrogen-related receptor gammatarget
DB00197TroglitazoneSteroid hormone receptor ERR1target
DB00197TroglitazoneCytochrome P450 19A1enzyme
DB00197TroglitazoneCytochrome P450 1A1enzyme
DB00197TroglitazoneCytochrome P450 2B6enzyme
DB00197TroglitazoneCytochrome P450 2C9enzyme
DB00197TroglitazoneCytochrome P450 3A5enzyme
DB00197TroglitazoneCytochrome P450 3A7enzyme
DB00197TroglitazoneUDP-glucuronosyltransferase 1-3enzyme
DB00197TroglitazoneUDP-glucuronosyltransferase 1-4enzyme
DB00197TroglitazoneUDP-glucuronosyltransferase 1-6enzyme
DB00197TroglitazoneUDP-glucuronosyltransferase 1-7enzyme
DB00197TroglitazoneUDP-glucuronosyltransferase 1-8enzyme
DB00197TroglitazoneUDP-glucuronosyltransferase 1-9enzyme
DB00197TroglitazoneUDP-glucuronosyltransferase 1-10enzyme
DB00197TroglitazoneUDP-glucuronosyltransferase 2B7enzyme
DB00197TroglitazoneUDP-glucuronosyltransferase 2B15enzyme
DB00197TroglitazonePeroxisome proliferator-activated receptor deltatarget
DB00197TroglitazonePeroxisome proliferator-activated receptor alphatarget
DB00197TroglitazoneGlutathione S-transferase Ptarget
DB00321AmitriptylineSodium-dependent serotonin transportertarget
DB00321AmitriptylineSodium-dependent noradrenaline transportertarget
DB00321AmitriptylinePotassium voltage-gated channel subfamily KQT member 2target
DB00321AmitriptylineAlpha-2A adrenergic receptortarget
DB00321AmitriptylineCytochrome P450 1A2enzyme
DB00321AmitriptylineCytochrome P450 2C19enzyme
DB00321AmitriptylineCytochrome P450 2D6enzyme
DB00321AmitriptylineSerum albumincarrier
DB00321AmitriptylineAlpha-1-acid glycoprotein 1carrier
DB00321AmitriptylineHistamine H1 receptortarget
DB00321Amitriptyline5-hydroxytryptamine receptor 2Atarget
DB00321Amitriptyline5-hydroxytryptamine receptor 1Atarget
DB00321AmitriptylineAlpha-1A adrenergic receptortarget
DB00321AmitriptylineCytochrome P450 3A4enzyme
DB00321AmitriptylineCytochrome P450 3A5enzyme
DB00321AmitriptylinePotassium voltage-gated channel subfamily A member 1target
DB00321AmitriptylineAlpha-1D adrenergic receptortarget
DB00321AmitriptylineDelta-type opioid receptortarget
DB00321AmitriptylineKappa-type opioid receptortarget
DB00321AmitriptylineHigh affinity nerve growth factor receptortarget
DB00321AmitriptylineBDNF/NT-3 growth factors receptortarget
DB00321AmitriptylineCytochrome P450 2C9enzyme
DB00321AmitriptylineCytochrome P450 2B6enzyme
DB00321AmitriptylineCytochrome P450 2C8enzyme
DB00321AmitriptylineHistamine H2 receptortarget
DB00321AmitriptylineHistamine H4 receptortarget
DB00321AmitriptylineSigma non-opioid intracellular receptor 1target
DB00321Amitriptyline5-hydroxytryptamine receptor 2Ctarget
DB00321AmitriptylineAlpha-1B adrenergic receptortarget
DB00321Amitriptyline5-hydroxytryptamine receptor 7target
DB00321Amitriptyline5-hydroxytryptamine receptor 1Dtarget
DB00321AmitriptylineMu-type opioid receptortarget
DB00321Amitriptyline5-hydroxytryptamine receptor 1Btarget
DB00321Amitriptyline5-hydroxytryptamine receptor 6target
DB00321AmitriptylinePotassium voltage-gated channel subfamily KQT member 3target
DB00321AmitriptylineUDP-glucuronosyltransferase 2B10enzyme
DB00321Amitriptyline5-hydroxytryptamine receptor 1Ctarget
DB00321AmitriptylineMuscarinic acetylcholine receptortarget
DB00321AmitriptylineHERG human cardiac K+ channeltarget
DB00321AmitriptylineP-glycoprotein 1transporter
DB00321AmitriptylineUDP-glucuronosyltransferase 1-4enzyme
DB00458ImipramineSodium-dependent noradrenaline transportertarget
DB00458ImipramineSodium-dependent serotonin transportertarget
DB00458ImipramineCytochrome P450 1A2enzyme
DB00458ImipramineCytochrome P450 2C19enzyme
DB00458ImipramineCytochrome P450 2D6enzyme
DB00458ImipramineHistamine H1 receptortarget
DB00458ImipramineAlpha-1A adrenergic receptortarget
DB00458Imipramine5-hydroxytryptamine receptor 2Atarget
DB00458ImipramineMuscarinic acetylcholine receptor M1target
DB00458ImipramineMuscarinic acetylcholine receptor M2target
DB00458ImipramineMuscarinic acetylcholine receptor M3target
DB00458ImipramineMuscarinic acetylcholine receptor M4target
DB00458ImipramineMuscarinic acetylcholine receptor M5target
DB00458ImipraminePotassium voltage-gated channel subfamily D member 2target
DB00458ImipraminePotassium voltage-gated channel subfamily D member 3target
DB00458ImipramineAlpha-1D adrenergic receptortarget
DB00458ImipramineAlpha-1-acid glycoprotein 1carrier
DB00458ImipramineSolute carrier family 22 member 2transporter
DB00458ImipramineSolute carrier family 22 member 3transporter
DB00458ImipramineP-glycoprotein 1transporter
DB00458ImipramineSolute carrier family 22 member 4transporter
DB00458ImipramineCytochrome P450 3A4enzyme
DB00458ImipramineCytochrome P450 2B6enzyme
DB00458ImipramineCytochrome P450 2C18enzyme
DB00458ImipramineCytochrome P450 2E1enzyme
DB00458ImipramineCytochrome P450 3A7enzyme
DB00458Imipramine5-hydroxytryptamine receptor 2Ctarget
DB00458ImipramineAlpha-1B adrenergic receptortarget
DB00458Imipramine5-hydroxytryptamine receptor 7target
DB00458ImipramineD(1) dopamine receptortarget
DB00458ImipramineDopamine D2 receptortarget
DB00458ImipraminePotassium voltage-gated channel subfamily H member 2target
DB00458ImipramineSodium-dependent dopamine transportertarget
DB00458Imipramine5-hydroxytryptamine receptor 1Atarget
DB00458Imipramine5-hydroxytryptamine receptor 6target
DB00458ImipraminePotassium voltage-gated channel subfamily H member 1target
DB00458ImipramineSerum albumincarrier
DB00458ImipramineAlpha-1-acid glycoprotein 2target
DB00503RitonavirHuman immunodeficiency virus type 1 proteasetarget
DB00503RitonavirCytochrome P450 2D6enzyme
DB00503RitonavirCytochrome P450 2C9enzyme
DB00503RitonavirCytochrome P450 2C19enzyme
DB00503RitonavirCytochrome P450 2B6enzyme
DB00503RitonavirCytochrome P450 2C8enzyme
DB00503RitonavirP-glycoprotein 1transporter
DB00503RitonavirMultidrug resistance-associated protein 1transporter
DB00503RitonavirCanalicular multispecific organic anion transporter 1transporter
DB00503RitonavirSolute carrier organic anion transporter family member 1A2transporter
DB00503RitonavirATP-binding cassette sub-family G member 2transporter
DB00503RitonavirSolute carrier organic anion transporter family member 1B1transporter
DB00503RitonavirCytochrome P450 1A2enzyme
DB00503RitonavirCytochrome P450 2E1enzyme
DB00503RitonavirNuclear receptor subfamily 1 group I member 2target
DB00503RitonavirSerum albumincarrier
DB00503RitonavirCytochrome P450 3A4enzyme
DB00503RitonavirCytochrome P450 3A5enzyme
DB00503RitonavirCytochrome P450 3A7enzyme
DB00503RitonavirCytochrome P450 3A43enzyme
DB00503RitonavirUDP-glucuronosyltransferase 1-1enzyme
DB00503RitonavirSolute carrier organic anion transporter family member 2B1transporter
DB00503RitonavirBile salt export pumptransporter
DB00532MephenytoinSodium channel protein type 5 subunit alphatarget
DB00532MephenytoinCytochrome P450 2B6enzyme
DB00532MephenytoinCytochrome P450 2C9enzyme
DB00532MephenytoinCytochrome P450 2C19enzyme
DB00532MephenytoinCytochrome P450 1A2enzyme
DB00532MephenytoinCytochrome P450 2D6enzyme
DB00532MephenytoinCytochrome P450 2C8enzyme
DB00532MephenytoinNuclear receptor subfamily 1 group I member 2target
DB00532MephenytoinThyroxine-binding globulincarrier
DB00752TranylcypromineAmine oxidase [flavin-containing] Btarget
DB00752TranylcypromineAmine oxidase [flavin-containing] Atarget
DB00752TranylcypromineCytochrome P450 2C19enzyme
DB00752TranylcypromineCytochrome P450 2A6enzyme
DB00752TranylcypromineCytochrome P450 2D6enzyme
DB00752TranylcypromineCytochrome P450 1A2enzyme
DB00752TranylcypromineCytochrome P450 2C9enzyme
DB00752TranylcypromineCytochrome P450 2E1enzyme
DB00776OxcarbazepineCytochrome P450 2C19enzyme
DB00776OxcarbazepineCytochrome P450 3A4enzyme
DB00776OxcarbazepineCytochrome P450 3A5enzyme
DB00776OxcarbazepineSerum albumincarrier
DB00776OxcarbazepineP-glycoprotein 1transporter
DB00776OxcarbazepineAldo-keto reductase family 1 member C1enzyme
DB00776OxcarbazepineAldo-keto reductase family 1 member C2enzyme
DB00776OxcarbazepineAldo-keto reductase family 1 member C3enzyme
DB00776OxcarbazepineAldo-keto reductase family 1 member C4enzyme
DB00776OxcarbazepineCarbonyl reductase [NADPH] 1enzyme
DB00776OxcarbazepineCarbonyl reductase [NADPH] 3enzyme
DB00776OxcarbazepineSodium channel proteintarget
DB01026KetoconazoleCytochrome P450 3A4enzyme
DB01026KetoconazoleCytochrome P450 2C9enzyme
DB01026KetoconazoleCytochrome P450 2C19enzyme
DB01026KetoconazoleCytochrome P450 3A5enzyme
DB01026KetoconazoleCytochrome P450 1A2enzyme
DB01026KetoconazoleCytochrome P450 2C8enzyme
DB01026KetoconazoleCytochrome P450 1A1enzyme
DB01026KetoconazoleCytochrome P450 2D6enzyme
DB01026KetoconazoleBile salt export pumptransporter
DB01026KetoconazoleP-glycoprotein 1transporter
DB01026KetoconazoleCytochrome P450 11B1, mitochondrialenzyme
DB01026KetoconazoleCytochrome P450 1B1enzyme
DB01026KetoconazoleCytochrome P450 2A6enzyme
DB01026KetoconazoleCytochrome P450 2B6enzyme
DB01026KetoconazoleLanosterol 14-alpha demethylasetarget
DB01026KetoconazoleAndrogen receptortarget
DB01026KetoconazoleSteroid 17-alpha-hydroxylase/17,20 lyasetarget
DB01026KetoconazoleSteroid 21-hydroxylasetarget
DB01026KetoconazolePotassium voltage-gated channel subfamily H member 2target
DB01026KetoconazoleNuclear receptor subfamily 1 group I member 2target
DB01026KetoconazoleNuclear receptor subfamily 1 group I member 3target
DB01026KetoconazoleUDP-glucuronosyltransferase 1-1enzyme
DB01026KetoconazoleUDP-glucuronosyltransferase 2B7enzyme
DB01026KetoconazoleSolute carrier organic anion transporter family member 1B1transporter
DB01026KetoconazoleCytochrome P450 4F12enzyme
DB01026KetoconazoleLeukotriene-B(4) omega-hydroxylase 1enzyme
DB01026KetoconazoleSerum albumincarrier
DB01026KetoconazoleSex hormone-binding globulincarrier
DB01026KetoconazoleCytochrome P450 19A1enzyme
DB01026KetoconazoleUDP-glucuronosyltransferase 1-7enzyme
DB01041ThalidomideTumor necrosis factortarget
DB01041ThalidomideNuclear factor NF-kappa-B p105 subunittarget
DB01041ThalidomideProstaglandin G/H synthase 2target
DB01041ThalidomideCytochrome P450 2C19enzyme
DB01041ThalidomideCytochrome P450 1A1enzyme
DB01041ThalidomideCytochrome P450 2E1enzyme
DB01041ThalidomideCytochrome P450 2C9enzyme
DB01041ThalidomideProstaglandin G/H synthase 1enzyme
DB01041ThalidomideProstaglandin G/H synthase 2enzyme
DB01041ThalidomideCytochrome P450 3A5enzyme
DB01041ThalidomideFibroblast growth factor receptor 2target
DB01041ThalidomideDNAtarget
DB01041ThalidomideProtein cereblontarget
DB01041Thalidomidealpha1-acid glycoproteintarget
DB01424AminophenazoneCytochrome P450 2C19enzyme
DB01424AminophenazoneCytochrome P450 1A2enzyme
DB01424AminophenazoneCytochrome P450 2C8enzyme
DB01424AminophenazoneSolute carrier family 22 member 6transporter
DB01424AminophenazoneCytochrome P450 2C9enzyme
DB01424AminophenazoneCytochrome P450 2D6enzyme
DB01424AminophenazoneCytochrome P450 3A4enzyme
DB01424AminophenazoneCytochrome P450 2C18enzyme
DB01424AminophenazoneSteroid 17-alpha-hydroxylase/17,20 lyaseenzyme
DB01095Fluvastatin3-hydroxy-3-methylglutaryl-coenzyme A reductasetarget
DB01095FluvastatinCytochrome P450 2C9enzyme
DB01095FluvastatinCytochrome P450 3A4enzyme
DB01095FluvastatinCytochrome P450 2C8enzyme
DB01095FluvastatinCytochrome P450 2D6enzyme
DB01095FluvastatinCytochrome P450 2C19enzyme
DB01095FluvastatinCytochrome P450 1A1enzyme
DB01095FluvastatinSolute carrier organic anion transporter family member 1B1transporter
DB01095FluvastatinSolute carrier organic anion transporter family member 1B3transporter
DB01095FluvastatinSolute carrier organic anion transporter family member 2B1transporter
DB01095FluvastatinSolute carrier family 15 member 1transporter
DB01095FluvastatinCytochrome P450 3A5enzyme
DB01095FluvastatinUDP-glucuronosyltransferase 1-1enzyme
DB01095FluvastatinUDP-glucuronosyltransferase 1-3enzyme
DB01095FluvastatinUDP-glucuronosyltransferase 2B7enzyme
DB01095FluvastatinCanalicular multispecific organic anion transporter 1transporter
DB01095FluvastatinCytochrome P450 2B6enzyme
DB01095FluvastatinHistone deacetylase 2target
DB00468QuininePlatelet glycoprotein IXtarget
DB00468QuinineIntermediate conductance calcium-activated potassium channel protein 4target
DB00468QuinineCytochrome P450 3A4enzyme
DB00468QuinineCytochrome P450 3A5enzyme
DB00468QuinineCytochrome P450 1A1enzyme
DB00468QuinineCytochrome P450 2D6enzyme
DB00468QuinineCytochrome P450 1A2enzyme
DB00468QuinineCytochrome P450 2C8enzyme
DB00468QuinineCytochrome P450 2C9enzyme
DB00468QuinineCytochrome P450 2C19enzyme
DB00468QuinineCytochrome P450 2E1enzyme
DB00468QuinineCytochrome P450 3A7enzyme
DB00468QuinineSolute carrier family 22 member 2transporter
DB00468QuinineSolute carrier family 22 member 1transporter
DB00468QuinineSolute carrier family 22 member 5transporter
DB00468QuinineP-glycoprotein 1transporter
DB00468QuinineSolute carrier organic anion transporter family member 1A2transporter
DB00468QuinineSolute carrier family 22 member 4transporter
DB00468QuinineFe(II)-protoporphyrin IXtarget
DB00468QuinineSolute carrier organic anion transporter family member 1B1transporter
DB00682WarfarinVitamin K epoxide reductase complex subunit 1target
DB00682WarfarinCytochrome P450 2C8enzyme
DB00682WarfarinCytochrome P450 1A2enzyme
DB00682WarfarinCytochrome P450 2C9enzyme
DB00682WarfarinAlpha-1-acid glycoprotein 1carrier
DB00682WarfarinSerum albumincarrier
DB00682WarfarinCytochrome P450 2C19enzyme
DB00682WarfarinCytochrome P450 3A4enzyme
DB00682WarfarinCytochrome P450 2C18enzyme
DB00682WarfarinNuclear receptor subfamily 1 group I member 2target
DB00829DiazepamTranslocator proteintarget
DB00829DiazepamGamma-aminobutyric acid receptor subunit alpha-1target
DB00829DiazepamGamma-aminobutyric acid receptor subunit alpha-2target
DB00829DiazepamGamma-aminobutyric acid receptor subunit alpha-3target
DB00829DiazepamCytochrome P450 3A4enzyme
DB00829DiazepamSerum albumincarrier
DB00829DiazepamCytochrome P450 2C9enzyme
DB00829DiazepamCytochrome P450 2C19enzyme
DB00829DiazepamCytochrome P450 3A5enzyme
DB00829DiazepamCytochrome P450 3A7enzyme
DB00829DiazepamGamma-aminobutyric acid receptor subunit alpha-5target
DB00829DiazepamGamma-aminobutyric acid receptor subunit beta-1target
DB00829DiazepamGamma-aminobutyric acid receptor subunit beta-2target
DB00829DiazepamGamma-aminobutyric acid receptor subunit beta-3target
DB00829DiazepamGamma-aminobutyric acid receptor subunit gamma-1target
DB00829DiazepamGamma-aminobutyric acid receptor subunit gamma-2target
DB00829DiazepamGamma-aminobutyric acid receptor subunit gamma-3target
DB00829DiazepamGamma-aminobutyric acid receptor subunit deltatarget
DB00829DiazepamGamma-aminobutyric acid receptor subunit epsilontarget
DB00829DiazepamGamma-aminobutyric acid receptor subunit pitarget
DB00829DiazepamGamma-aminobutyric acid receptor subunit rho-1target
DB00829DiazepamGamma-aminobutyric acid receptor subunit rho-2target
DB00829DiazepamGamma-aminobutyric acid receptor subunit rho-3target
DB00829DiazepamGamma-aminobutyric acid receptor subunit thetatarget
DB00829DiazepamP-glycoprotein 1transporter
DB00829DiazepamCytochrome P450 2B6enzyme
DB00829DiazepamProstaglandin G/H synthase 1enzyme
DB00829DiazepamCytochrome P450 2C18enzyme
DB00829DiazepamCytochrome P450 2C8enzyme
DB00829DiazepamCytochrome P450 2E1enzyme
DB00829DiazepamGABA-A receptor (anion channel)target
DB00501CimetidineHistamine H2 receptortarget
DB00501CimetidineCytochrome P450 1A2enzyme
DB00501CimetidineCytochrome P450 2D6enzyme
DB00501CimetidineCytochrome P450 2C19enzyme
DB00501CimetidineCytochrome P450 3A4enzyme
DB00501CimetidineCytochrome P450 3A5enzyme
DB00501CimetidineP-glycoprotein 1transporter
DB00501CimetidineSolute carrier family 22 member 2transporter
DB00501CimetidineSolute carrier family 22 member 1transporter
DB00501CimetidineSolute carrier family 22 member 3transporter
DB00501CimetidineSolute carrier family 22 member 5transporter
DB00501CimetidineSolute carrier family 22 member 6transporter
DB00501CimetidineSolute carrier family 22 member 8transporter
DB00501CimetidineMultidrug and toxin extrusion protein 1transporter
DB00501CimetidineSolute carrier family 22 member 4transporter
DB00501CimetidineSolute carrier family 22 member 11transporter
DB00501CimetidineSolute carrier family 22 member 7transporter
DB00501CimetidineCytochrome P450 11B1, mitochondrialenzyme
DB00501CimetidineCytochrome P450 2C8enzyme
DB00501CimetidineCytochrome P450 2C9enzyme
DB00501CimetidineCytochrome P450 2E1enzyme
DB00501CimetidineDimethylaniline monooxygenase [N-oxide-forming] 3enzyme
DB00501CimetidineDimethylaniline monooxygenase [N-oxide-forming] 1enzyme
DB00501CimetidineBile salt export pumptransporter
DB00501CimetidineMultidrug and toxin extrusion protein 2transporter
DB01032ProbenecidSolute carrier family 22 member 8target
DB01032ProbenecidSolute carrier family 22 member 11target
DB01032ProbenecidSerum albumincarrier
DB01032ProbenecidSolute carrier family 22 member 2transporter
DB01032ProbenecidSolute carrier family 22 member 1transporter
DB01032ProbenecidCanalicular multispecific organic anion transporter 2transporter
DB01032ProbenecidMultidrug resistance-associated protein 4transporter
DB01032ProbenecidMultidrug resistance-associated protein 5transporter
DB01032ProbenecidMonocarboxylate transporter 2transporter
DB01032ProbenecidSolute carrier family 22 member 5transporter
DB01032ProbenecidMultidrug resistance-associated protein 6transporter
DB01032ProbenecidMultidrug resistance-associated protein 1transporter
DB01032ProbenecidSolute carrier organic anion transporter family member 1A2transporter
DB01032ProbenecidMonocarboxylate transporter 1transporter
DB01032ProbenecidSodium/bile acid cotransportertransporter
DB01032ProbenecidSolute carrier family 22 member 6transporter
DB01032ProbenecidSolute carrier family 22 member 10transporter
DB01032ProbenecidSolute carrier family 22 member 8transporter
DB01032ProbenecidCanalicular multispecific organic anion transporter 1transporter
DB01032ProbenecidATP-binding cassette sub-family C member 11transporter
DB01032ProbenecidSolute carrier family 22 member 11transporter
DB01032ProbenecidSolute carrier organic anion transporter family member 1C1transporter
DB01032ProbenecidSolute carrier family 22 member 7transporter
DB01032ProbenecidSolute carrier family 22 member 6target
DB01032ProbenecidPannexin-1target
DB01032ProbenecidCytochrome P450 2C8enzyme
DB01032ProbenecidCytochrome P450 3A4enzyme
DB01032ProbenecidSolute carrier family 22 member 12transporter
DB01032ProbenecidSolute carrier family 2, facilitated glucose transporter member 9transporter
DB01032ProbenecidTaste receptor type 2 member 16target
DB01032ProbenecidUDP-glucuronosyltransferase 1-1enzyme
DB01032ProbenecidCytochrome P450 2C9enzyme
DB00564CarbamazepineVoltage-gated sodium channel alpha subunittarget
DB00564CarbamazepineCytochrome P450 2C8enzyme
DB00564CarbamazepineCytochrome P450 2B6enzyme
DB00564CarbamazepineCytochrome P450 3A4enzyme
DB00564CarbamazepineCytochrome P450 1A2enzyme
DB00564CarbamazepineCytochrome P450 2C19enzyme
DB00564CarbamazepineCytochrome P450 2C9enzyme
DB00564CarbamazepineP-glycoprotein 1transporter
DB00564CarbamazepineCytochrome P450 3A5enzyme
DB00564CarbamazepineUDP-glucuronosyltransferase 2B7enzyme
DB00564CarbamazepineRalA-binding protein 1transporter
DB00564CarbamazepineCanalicular multispecific organic anion transporter 1transporter
DB00564CarbamazepineNeuronal acetylcholine receptor subunit alpha-4target
DB00564CarbamazepineNuclear receptor subfamily 1 group I member 2target
DB00564CarbamazepineUDP-glucuronosyltransferase 1-1enzyme
DB00564CarbamazepineUDP-glucuronosyltransferase 1-6enzyme
DB00564CarbamazepineUDP-glucuronosyltransferase 1-7enzyme
DB00921BuprenorphineKappa-type opioid receptortarget
DB00921BuprenorphineMu-type opioid receptortarget
DB00921BuprenorphineCytochrome P450 3A4enzyme
DB00921BuprenorphineCytochrome P450 2D6enzyme
DB00921BuprenorphineP-glycoprotein 1transporter
DB00921BuprenorphineATP-binding cassette sub-family G member 2transporter
DB00921BuprenorphineCytochrome P450 2C9enzyme
DB00921BuprenorphineCytochrome P450 3A5enzyme
DB00921BuprenorphineCytochrome P450 2C8enzyme
DB00921BuprenorphineCytochrome P450 3A7enzyme
DB00921BuprenorphineDelta-type opioid receptortarget
DB00921BuprenorphineCytochrome P450 2C18enzyme
DB00921BuprenorphineCytochrome P450 2C19enzyme
DB00921BuprenorphineNociceptin receptortarget
DB00091CyclosporineCalcium signal-modulating cyclophilin ligandtarget
DB00091CyclosporinePeptidyl-prolyl cis-trans isomerase Atarget
DB00091CyclosporineCalcineurin subunit B type 2target
DB00091CyclosporineCytochrome P450 3A5enzyme
DB00091CyclosporineCytochrome P450 3A4enzyme
DB00091CyclosporineCytochrome P450 3A7enzyme
DB00091CyclosporineP-glycoprotein 1transporter
DB00091CyclosporineCanalicular multispecific organic anion transporter 2transporter
DB00091CyclosporineBile salt export pumptransporter
DB00091CyclosporineSolute carrier organic anion transporter family member 1A2transporter
DB00091CyclosporineIleal sodium/bile acid cotransportertransporter
DB00091CyclosporineSodium/bile acid cotransportertransporter
DB00091CyclosporineSolute carrier family 22 member 6transporter
DB00091CyclosporineMultidrug resistance-associated protein 7transporter
DB00091CyclosporineCanalicular multispecific organic anion transporter 1transporter
DB00091CyclosporineATP-binding cassette sub-family G member 2transporter
DB00091CyclosporineSolute carrier organic anion transporter family member 1B1transporter
DB00091CyclosporineCytochrome P450 2C19enzyme
DB00091CyclosporineCytochrome P450 2C9enzyme
DB00091CyclosporineCytochrome P450 2D6enzyme
DB00091CyclosporinePeptidyl-prolyl cis-trans isomerase F, mitochondrialtarget
DB00091CyclosporineSolute carrier organic anion transporter family member 1B3transporter
DB01093Dimethyl sulfoxideTransthyretincarrier
DB01093Dimethyl sulfoxideCytochrome P450 2C19enzyme
DB01093Dimethyl sulfoxideCytochrome P450 2D6enzyme
DB01093Dimethyl sulfoxideCytochrome P450 3A4enzyme
DB00678LosartanType-1 angiotensin II receptortarget
DB00678LosartanCytochrome P450 3A4enzyme
DB00678LosartanCytochrome P450 2C9enzyme
DB00678LosartanP-glycoprotein 1transporter
DB00678LosartanSolute carrier family 22 member 6transporter
DB00678LosartanUDP-glucuronosyltransferase 1-1enzyme
DB00678LosartanUDP-glucuronosyltransferase 1-3enzyme
DB00678LosartanUDP-glucuronosyltransferase 1-10enzyme
DB00678LosartanUDP-glucuronosyltransferase 2B7enzyme
DB00678LosartanUDP-glucuronosyltransferase 2B17enzyme
DB00678LosartanCytochrome P450 2C19enzyme
DB00678LosartanSerum albumincarrier
DB00678LosartanSolute carrier family 22 member 12transporter
DB00678LosartanSolute carrier family 2, facilitated glucose transporter member 9transporter
DB00678LosartanBile salt export pumptransporter
DB00678LosartanCytochrome P450 2C8enzyme
DB00780PhenelzineMembrane primary amine oxidasetarget
DB00780PhenelzineAmine oxidase [flavin-containing] Btarget
DB00780PhenelzineAmine oxidase [flavin-containing] Atarget
DB00780PhenelzineAmine oxidase [flavin-containing] Aenzyme
DB00780PhenelzineAmine oxidase [flavin-containing] Benzyme
DB00780PhenelzineCytochrome P450 2E1enzyme
DB00780Phenelzine4-aminobutyrate aminotransferase, mitochondrialtarget
DB00780PhenelzineGlutamic acid decarboxylasetarget
DB00780PhenelzineAlanine aminotransferase 1target
DB00780PhenelzineAlanine aminotransferase 2target
DB00780PhenelzineCytochrome P450 2C19enzyme
DB00780PhenelzineCytochrome P450 2C8enzyme
DB00780PhenelzineCytochrome P450 3A4enzyme
DB00780PhenelzineCytochrome P450 3A5enzyme
DB00780PhenelzineCytochrome P450 3A7enzyme
DB00780PhenelzineCytochrome P450 2D6enzyme
DB00780PhenelzineCytochrome P450 3A Subfamilyenzyme
DB00259SulfanilamideDihydropteroate synthasetarget
DB00259SulfanilamideCytochrome P450 2C19enzyme
DB00259SulfanilamideCytochrome P450 2D6enzyme
DB00259SulfanilamideCytochrome P450 2E1enzyme
DB00259SulfanilamideCytochrome P450 3A4enzyme
DB00966TelmisartanType-1 angiotensin II receptortarget
DB00966TelmisartanPeroxisome proliferator-activated receptor gammatarget
DB00966TelmisartanP-glycoprotein 1transporter
DB00966TelmisartanCanalicular multispecific organic anion transporter 1transporter
DB00966TelmisartanATP-binding cassette sub-family G member 2transporter
DB00966TelmisartanCytochrome P450 2C19enzyme
DB00966TelmisartanBile salt export pumptransporter
DB00966TelmisartanUDP-glucuronosyltransferase 1-3enzyme
DB00763MethimazoleThyroid peroxidasetarget
DB00763MethimazoleCytochrome P450 1A2enzyme
DB00763MethimazoleCytochrome P450 2A6enzyme
DB00763MethimazoleCytochrome P450 2B6enzyme
DB00763MethimazoleCytochrome P450 2C19enzyme
DB00763MethimazoleCytochrome P450 2C9enzyme
DB00763MethimazoleCytochrome P450 2D6enzyme
DB00763MethimazoleCytochrome P450 2E1enzyme
DB00763MethimazoleCytochrome P450 3A4enzyme
DB00763MethimazoleDimethylaniline monooxygenase [N-oxide-forming] 3enzyme
DB00313Valproic acidHistone deacetylase 9target
DB00313Valproic acidShort/branched chain specific acyl-CoA dehydrogenase, mitochondrialtarget
DB00313Valproic acidCytochrome P450 2A6enzyme
DB00313Valproic acidCytochrome P450 2B6enzyme
DB00313Valproic acidCytochrome P450 2C9enzyme
DB00313Valproic acidSolute carrier family 22 member 5transporter
DB00313Valproic acidSolute carrier family 22 member 6transporter
DB00313Valproic acidSolute carrier family 22 member 8transporter
DB00313Valproic acidMonocarboxylate transporter 1transporter
DB00313Valproic acidSolute carrier family 22 member 7transporter
DB00313Valproic acidCytochrome P450 3A5enzyme
DB00313Valproic acidUDP-glucuronosyltransferase 1-9enzyme
DB00313Valproic acidProstaglandin G/H synthase 1enzyme
DB00313Valproic acidCytochrome P450 1A2enzyme
DB00313Valproic acidCytochrome P450 2C19enzyme
DB00313Valproic acidCytochrome P450 3A4enzyme
DB00313Valproic acidUDP-glucuronosyltransferase 1-4enzyme
DB00313Valproic acidUDP-glucuronosyltransferase 1-8enzyme
DB00313Valproic acidUDP-glucuronosyltransferase 1-10enzyme
DB00313Valproic acidUDP-glucuronosyltransferase 1-6enzyme
DB00313Valproic acidUDP-glucuronosyltransferase 1-3enzyme
DB00313Valproic acidUDP-glucuronosyltransferase 2B7enzyme
DB00313Valproic acidUDP-glucuronosyltransferase 2B15enzyme
DB00313Valproic acid2-oxoglutarate dehydrogenase, mitochondrialtarget
DB00313Valproic acidSuccinate-semialdehyde dehydrogenase, mitochondrialtarget
DB00313Valproic acidSodium channel proteintarget
DB00313Valproic acidHistone deacetylase 2target
DB00313Valproic acidPeroxisome proliferator-activated receptor alphatarget
DB00313Valproic acidPeroxisome proliferator-activated receptor deltatarget
DB00313Valproic acidPeroxisome proliferator-activated receptor gammatarget
DB00313Valproic acidSerum albumincarrier
DB00313Valproic acidUDP-glucuronosyltransferase 1-1enzyme
DB00313Valproic acidSolute carrier organic anion transporter family member 2B1transporter
DB00398SorafenibSerine/threonine-protein kinase B-raftarget
DB00398SorafenibReceptor-type tyrosine-protein kinase FLT3target
DB00398SorafenibRAF proto-oncogene serine/threonine-protein kinasetarget
DB00398SorafenibVascular endothelial growth factor receptor 3target
DB00398SorafenibPlatelet-derived growth factor receptor betatarget
DB00398SorafenibMast/stem cell growth factor receptor Kittarget
DB00398SorafenibVascular endothelial growth factor receptor 2target
DB00398SorafenibCytochrome P450 3A4enzyme
DB00398SorafenibUDP-glucuronosyltransferase 1-9enzyme
DB00398SorafenibCytochrome P450 2B6enzyme
DB00398SorafenibCytochrome P450 2C8enzyme
DB00398SorafenibCytochrome P450 3A5enzyme
DB00398SorafenibCytochrome P450 3A7enzyme
DB00398SorafenibCytochrome P450 2C9enzyme
DB00398SorafenibMultidrug resistance-associated protein 4transporter
DB00398SorafenibP-glycoprotein 1transporter
DB00398SorafenibCanalicular multispecific organic anion transporter 1transporter
DB00398SorafenibATP-binding cassette sub-family G member 2transporter
DB00398SorafenibCytochrome P450 1A2enzyme
DB00398SorafenibCytochrome P450 2C19enzyme
DB00398SorafenibCytochrome P450 2D6enzyme
DB00398SorafenibUDP-glucuronosyltransferase 1-1enzyme
DB00398SorafenibRalA-binding protein 1transporter
DB00398SorafenibFibroblast growth factor receptor 1target
DB00398SorafenibProto-oncogene tyrosine-protein kinase receptor Rettarget
DB00398SorafenibVascular endothelial growth factor receptor 1target
DB00398SorafenibSolute carrier organic anion transporter family member 1B1transporter
DB01128BicalutamideAndrogen receptortarget
DB01128BicalutamideCytochrome P450 3A4enzyme
DB01128BicalutamideCytochrome P450 2C19enzyme
DB01128BicalutamideCytochrome P450 2C9enzyme
DB01128BicalutamideCytochrome P450 2D6enzyme
DB04920ClevidipineVoltage-dependent L-type calcium channel subunit alpha-1Ftarget
DB04920ClevidipineVoltage-dependent L-type calcium channel subunit alpha-1Starget
DB04920ClevidipineVoltage-dependent L-type calcium channel subunit alpha-1Dtarget
DB04920ClevidipineVoltage-dependent L-type calcium channel subunit alpha-1Ctarget
DB04920ClevidipineCytochrome P450 2C9enzyme
DB04920ClevidipineCytochrome P450 2D6enzyme
DB04920ClevidipineCytochrome P450 2E1enzyme
DB04920ClevidipineCytochrome P450 2C19enzyme
DB04920ClevidipineCytochrome P450 3A4enzyme
DB04920ClevidipineCholinesteraseenzyme
DB08828VismodegibSmoothened homologtarget
DB08828VismodegibCytochrome P450 2C9enzyme
DB08828VismodegibCytochrome P450 3A4enzyme
DB08828VismodegibP-glycoprotein 1transporter
DB08828VismodegibCytochrome P450 2C8enzyme
DB08828VismodegibCytochrome P450 2C19enzyme
DB08828VismodegibATP-binding cassette sub-family G member 2transporter
DB08828VismodegibSerum albumincarrier
DB08828VismodegibAlpha-1-acid glycoprotein 1carrier
DB09054IdelalisibPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoformtarget
DB09054IdelalisibATP-binding cassette sub-family G member 2transporter
DB09054IdelalisibP-glycoprotein 1transporter
DB09054IdelalisibAldehyde oxidaseenzyme
DB09054IdelalisibUDP-glucuronosyltransferase 1-4enzyme
DB09054IdelalisibUDP-glucuronosyltransferase 1-4enzyme
DB09054IdelalisibCytochrome P450 2C8enzyme
DB09054IdelalisibCytochrome P450 2C19enzyme
DB09054IdelalisibCytochrome P450 2B6enzyme
DB09054IdelalisibCytochrome P450 3A4enzyme
DB09054IdelalisibSolute carrier organic anion transporter family member 1B1transporter
DB09054IdelalisibSolute carrier organic anion transporter family member 1B3transporter
DB09054IdelalisibCytochrome P450 3A5enzyme
DB09054IdelalisibCytochrome P450 3A43enzyme
DB09054IdelalisibCytochrome P450 3A7enzyme
DB01685TopiroxostatXanthine dehydrogenase/oxidasetarget
DB01685TopiroxostatATP-binding cassette sub-family G member 2transporter
DB01685TopiroxostatSerum albumincarrier
DB01685TopiroxostatAlpha-1-acid glycoprotein 1carrier
DB01685TopiroxostatCytochrome P450 2C8enzyme
DB01685TopiroxostatCytochrome P450 2C9enzyme
DB01685TopiroxostatCytochrome P450 1A1enzyme
DB01685TopiroxostatCytochrome P450 3A4enzyme
DB01685TopiroxostatCytochrome P450 2C19enzyme
DB01685TopiroxostatSolute carrier family 22 member 8transporter
DB01685TopiroxostatSolute carrier family 22 member 6transporter
DB01685TopiroxostatUDP-glucuronosyltransferase 1-9enzyme
DB09198LobeglitazoneSolute carrier organic anion transporter family member 1B1transporter
DB09198LobeglitazoneSolute carrier organic anion transporter family member 3A1transporter
DB09198LobeglitazoneP-glycoprotein 1transporter
DB09198LobeglitazoneCytochrome P450 1A2enzyme
DB09198LobeglitazoneCytochrome P450 2C9enzyme
DB09198LobeglitazoneCytochrome P450 2C19enzyme
DB09198LobeglitazonePeroxisome proliferator-activated receptor gammatarget
DB09198LobeglitazoneCytochrome P450 3A4enzyme
DB09198LobeglitazoneCytochrome P450 2C8enzyme
DB09167Dosulepin5-hydroxytryptamine receptor 1Atarget
DB09167Dosulepin5-hydroxytryptamine receptor 2Atarget
DB09167DosulepinCytochrome P450 2D6enzyme
DB09167DosulepinCytochrome P450 1A2enzyme
DB09167DosulepinCytochrome P450 2C19enzyme
DB09167DosulepinCytochrome P450 2C9enzyme
DB09167DosulepinHistamine H1 receptortarget
DB09167DosulepinMuscarinic acetylcholine receptor M1target
DB09167DosulepinMuscarinic acetylcholine receptor M2target
DB09167DosulepinMuscarinic acetylcholine receptor M3target
DB09167DosulepinMuscarinic acetylcholine receptor M4target
DB09167DosulepinMuscarinic acetylcholine receptor M5target
DB09167DosulepinSodium-dependent noradrenaline transportertarget
DB09167DosulepinSodium-dependent serotonin transportertarget
DB09167DosulepinAlpha-1 adrenergic receptorstarget
DB09167DosulepinAlpha-2 adrenergic receptorstarget
DB12319BenzbromaroneCytochrome P450 2C9target
DB12319BenzbromaroneCytochrome P450 2C19target
DB12319BenzbromaroneSolute carrier organic anion transporter family member 1B1transporter
DB12319BenzbromaroneSolute carrier organic anion transporter family member 2B1transporter
DB12319BenzbromaroneBile salt export pumptransporter
DB12319BenzbromaroneCytochrome P450 2C19enzyme
DB13874EnasidenibCytochrome P450 1A2enzyme
DB13874EnasidenibCytochrome P450 2B6enzyme
DB13874EnasidenibIsocitrate dehydrogenase [NADP], mitochondrialtarget
DB13874EnasidenibCytochrome P450 2C8enzyme
DB13874EnasidenibCytochrome P450 2C9enzyme
DB13874EnasidenibCytochrome P450 2C19enzyme
DB13874EnasidenibCytochrome P450 2D6enzyme
DB13874EnasidenibCytochrome P450 3A4enzyme
DB13874EnasidenibUDP-glucuronosyltransferase 1-1enzyme
DB13874EnasidenibUDP-glucuronosyltransferase 1-3enzyme
DB13874EnasidenibUDP-glucuronosyltransferase 1-4enzyme
DB13874EnasidenibUDP-glucuronosyltransferase 1-9enzyme
DB13874EnasidenibUDP-glucuronosyltransferase 2B7enzyme
DB13874EnasidenibUDP-glucuronosyltransferase 2B15enzyme
DB13874EnasidenibP-glycoprotein 1transporter
DB13874EnasidenibATP-binding cassette sub-family G member 2transporter
DB13874EnasidenibSolute carrier family 22 member 6transporter
DB13874EnasidenibSolute carrier organic anion transporter family member 1B1transporter
DB13874EnasidenibSolute carrier family 22 member 2transporter
DB13874EnasidenibSolute carrier organic anion transporter family member 1B3transporter
DB13874EnasidenibSolute carrier family 22 member 8transporter
DB13941PiperaquineCytochrome P450 3A4enzyme
DB13941PiperaquineCytochrome P450 2C19enzyme
DB13941PiperaquineCytochrome P450 2C9enzyme
DB13941PiperaquineCytochrome P450 2B6enzyme
DB13941PiperaquineCytochrome P450 2E1enzyme
DB11633IsavuconazoleCytochrome P450 3A4enzyme
DB11633IsavuconazoleCytochrome P450 3A5enzyme
DB11633IsavuconazoleCytochrome P450 2C8enzyme
DB11633IsavuconazoleCytochrome P450 2C9enzyme
DB11633IsavuconazoleCytochrome P450 2C19enzyme
DB11633IsavuconazoleCytochrome P450 2D6enzyme
DB11633IsavuconazoleCytochrome P450 2B6enzyme
DB11633IsavuconazoleUDP-glucuronosyltransferase 1-9enzyme
DB11633IsavuconazoleUDP-glucuronosyltransferase 1-8enzyme
DB11633IsavuconazoleP-glycoprotein 1transporter
DB11633IsavuconazoleATP-binding cassette sub-family G member 2transporter
DB11633IsavuconazoleSolute carrier family 22 member 2transporter
DB11633IsavuconazoleLanosterol 14-alpha demethylasetarget
DB11633IsavuconazolePotassium voltage-gated channel subfamily H member 2target
DB11633IsavuconazoleVoltage-dependent L-type calcium channel subunit alpha-1Ctarget
DB11633IsavuconazoleG protein-activated inward rectifier potassium channel 2target
DB11633IsavuconazoleG protein-activated inward rectifier potassium channel 3target
DB11633IsavuconazoleATP-sensitive inward rectifier potassium channel 11target
DB11633IsavuconazolePotassium voltage-gated channel subfamily A member 5target
DB11633IsavuconazolePotassium voltage-gated channel subfamily D member 3target
DB11633IsavuconazolePotassium voltage-gated channel subfamily KQT member 1target
DB11633IsavuconazoleSodium channel protein type 5 subunit alphatarget
DB06654SafinamideAmine oxidase [flavin-containing] Btarget
DB06654SafinamideAmine oxidase [flavin-containing] Aenzyme
DB06654SafinamideATP-binding cassette sub-family G member 2transporter
DB06654SafinamideSolute carrier organic anion transporter family member 3A1transporter
DB06654SafinamideCytochrome P450 3A4enzyme
DB06654SafinamideCytochrome P450 1A1enzyme
DB06654SafinamideCytochrome P450 1A2enzyme
DB06654SafinamideCytochrome P450 2B6enzyme
DB06654SafinamideCytochrome P450 2C9enzyme
DB06654SafinamideCytochrome P450 2D6enzyme
DB06654SafinamideCytochrome P450 2C19enzyme
DB06654SafinamideCytochrome P450 2E1enzyme
DB06654SafinamideCytochrome P450 3A5enzyme
DB09078LenvatinibVascular endothelial growth factor receptor 1target
DB09078LenvatinibVascular endothelial growth factor receptor 2target
DB09078LenvatinibVascular endothelial growth factor receptor 3target
DB09078LenvatinibFibroblast growth factor receptor 1target
DB09078LenvatinibFibroblast growth factor receptor 2target
DB09078LenvatinibFibroblast growth factor receptor 3target
DB09078LenvatinibFibroblast growth factor receptor 4target
DB09078LenvatinibPlatelet-derived growth factor receptor alphatarget
DB09078LenvatinibProto-oncogene tyrosine-protein kinase receptor Rettarget
DB09078LenvatinibMast/stem cell growth factor receptor Kittarget
DB09078LenvatinibP-glycoprotein 1transporter
DB09078LenvatinibATP-binding cassette sub-family G member 2transporter
DB09078LenvatinibCytochrome P450 3A4enzyme
DB09078LenvatinibAldehyde oxidaseenzyme
DB09078LenvatinibCytochrome P450 2C8enzyme
DB09078LenvatinibCytochrome P450 2C9enzyme
DB09078LenvatinibCytochrome P450 1A2enzyme
DB09078LenvatinibCytochrome P450 2B6enzyme
DB09078LenvatinibCytochrome P450 2C19enzyme
DB09078LenvatinibSolute carrier family 22 member 6transporter
DB09078LenvatinibSolute carrier family 22 member 8transporter
DB09078LenvatinibSolute carrier family 22 member 2transporter
DB09078LenvatinibSolute carrier organic anion transporter family member 1B1transporter
DB09078LenvatinibBile salt export pumptransporter
DB09078LenvatinibCytochrome P450 2D6enzyme
DB05246MethsuximideCytochrome P450 2C19enzyme
DB05246MethsuximideVoltage-dependent T-type calcium channel subunit alpha-1Gtarget
DB06414EtravirineCytochrome P450 2C19enzyme
DB06414EtravirineCytochrome P450 2C9enzyme
DB06414EtravirineCytochrome P450 3A4enzyme
DB06414EtravirineGag-Pol polyproteintarget
DB06414EtravirineGag-Pol polyproteintarget
DB06414EtravirineP-glycoprotein 1transporter
DB06414EtravirineMultidrug resistance protein 3transporter
DB00745ModafinilSodium-dependent dopamine transportertarget
DB00745ModafinilAlpha-1B adrenergic receptortarget
DB00745ModafinilCytochrome P450 3A4enzyme
DB00745ModafinilCytochrome P450 2C19enzyme
DB00745ModafinilCytochrome P450 1A2enzyme
DB00745ModafinilCytochrome P450 2B6enzyme
DB00745ModafinilCytochrome P450 2C9enzyme
DB00745ModafinilCytochrome P450 3A5enzyme
DB01118AmiodaroneBeta-1 adrenergic receptortarget
DB01118AmiodaronePotassium voltage-gated channel subfamily H member 2target
DB01118AmiodaroneCytochrome P450 2C8enzyme
DB01118AmiodaroneCytochrome P450 2C9enzyme
DB01118AmiodaroneCytochrome P450 2D6enzyme
DB01118AmiodaroneVoltage-dependent T-type calcium channel subunit alpha-1Htarget
DB01118AmiodaroneVoltage-dependent calcium channel subunit alpha-2/delta-2target
DB01118AmiodaroneCytochrome P450 3A4enzyme
DB01118AmiodaroneCytochrome P450 1A2enzyme
DB01118AmiodaroneCytochrome P450 1A1enzyme
DB01118AmiodaroneP-glycoprotein 1transporter
DB01118AmiodaroneCytochrome P450 2C19enzyme
DB01118AmiodaroneCytochrome P450 2A6enzyme
DB01118AmiodaroneThyroid hormone receptor alphatarget
DB01118AmiodaroneThyroid hormone receptor betatarget
DB01118AmiodaronePeroxisome proliferator-activated receptor gammatarget
DB01118AmiodaroneBile salt export pumptransporter
DB01118AmiodaroneSolute carrier family 22 member 2transporter
DB01118AmiodaroneCytochrome P450 2J2enzyme
DB00972AzelastineHistamine H1 receptortarget
DB00972AzelastineCytochrome P450 1A2enzyme
DB00972AzelastineCytochrome P450 2D6enzyme
DB00972AzelastineCytochrome P450 3A4enzyme
DB00972AzelastineCytochrome P450 2C19enzyme
DB00972AzelastineCytochrome P450 1A1enzyme
DB00972AzelastineCytochrome P450 3A5enzyme
DB00972AzelastineCytochrome P450 2C9enzyme
DB00972AzelastineCytochrome P450 2C8enzyme
DB00972AzelastineP-glycoprotein 1transporter
DB00972AzelastineCytochrome P450 2A6enzyme
DB00972AzelastineCytochrome P450 2E1enzyme
DB00972AzelastineHistamine H2 receptortarget
DB00972AzelastinePhospholipase A2target
DB00972AzelastineLeukotriene C4 synthasetarget
DB00972AzelastineCytochrome P450 2B6enzyme
DB06268SitaxentanCytochrome P450 2C19enzyme
DB06268SitaxentanCytochrome P450 2C9enzyme
DB06268SitaxentanCytochrome P450 3A4enzyme
DB06268SitaxentanEndothelin-1 receptortarget
DB06268SitaxentanEndothelin B receptortarget
DB00363ClozapineDopamine D4 receptortarget
DB00363ClozapineHistamine H1 receptortarget
DB00363ClozapineDopamine D2 receptortarget
DB00363ClozapineNeuron-specific vesicular protein calcyontarget
DB00363ClozapineHistamine H4 receptortarget
DB00363Clozapine5-hydroxytryptamine receptor 2Atarget
DB00363Clozapine5-hydroxytryptamine receptor 1Atarget
DB00363Clozapine5-hydroxytryptamine receptor 2Ctarget
DB00363ClozapineDopamine D1 receptortarget
DB00363ClozapineCytochrome P450 1A2enzyme
DB00363ClozapineCytochrome P450 2D6enzyme
DB00363ClozapineDopamine D3 receptortarget
DB00363ClozapineMuscarinic acetylcholine receptor M1target
DB00363ClozapineMuscarinic acetylcholine receptor M2target
DB00363ClozapineMuscarinic acetylcholine receptor M3target
DB00363ClozapineMuscarinic acetylcholine receptor M4target
DB00363ClozapineMuscarinic acetylcholine receptor M5target
DB00363Clozapine5-hydroxytryptamine receptor 1Btarget
DB00363Clozapine5-hydroxytryptamine receptor 1Dtarget
DB00363Clozapine5-hydroxytryptamine receptor 1Etarget
DB00363Clozapine5-hydroxytryptamine receptor 3Atarget
DB00363Clozapine5-hydroxytryptamine receptor 6target
DB00363Clozapine5-hydroxytryptamine receptor 7target
DB00363ClozapineAlpha-1A adrenergic receptortarget
DB00363ClozapineAlpha-1B adrenergic receptortarget
DB00363ClozapineAlpha-2A adrenergic receptortarget
DB00363ClozapineAlpha-2B adrenergic receptortarget
DB00363ClozapineAlpha-2C adrenergic receptortarget
DB00363ClozapineCytochrome P450 2C9enzyme
DB00363ClozapineP-glycoprotein 1transporter
DB00363ClozapineCytochrome P450 3A4enzyme
DB00363ClozapineCytochrome P450 2C19enzyme
DB00363ClozapineDimethylaniline monooxygenase [N-oxide-forming] 3enzyme
DB00363ClozapineUDP-glucuronosyltransferase 1-4enzyme
DB00363ClozapineCytochrome P450 1A1enzyme
DB00363ClozapineCytochrome P450 2A6enzyme
DB00363ClozapineCytochrome P450 2C8enzyme
DB00363ClozapineGlutathione S-transferase Ptarget
DB00701AmprenavirHuman immunodeficiency virus type 1 proteasetarget
DB00701AmprenavirCytochrome P450 3A4enzyme
DB00701AmprenavirP-glycoprotein 1transporter
DB00701AmprenavirMultidrug resistance-associated protein 1transporter
DB00701AmprenavirCytochrome P450 2B6enzyme
DB00701AmprenavirCytochrome P450 2C19enzyme
DB00701AmprenavirCytochrome P450 2C9enzyme
DB00701AmprenavirCytochrome P450 2D6enzyme
DB00701AmprenavirCytochrome P450 3A5enzyme
DB00701AmprenavirSolute carrier organic anion transporter family member 1B1transporter
DB01110MiconazoleCytochrome P450 2C9enzyme
DB01110MiconazoleCytochrome P450 2D6enzyme
DB01110MiconazoleCytochrome P450 3A4enzyme
DB01110MiconazoleP-glycoprotein 1transporter
DB01110MiconazoleCytochrome P450 51target
DB01110MiconazoleNitric oxide synthase, endothelialtarget
DB01110MiconazoleNitric oxide synthase, inducibletarget
DB01110MiconazoleCalcium-activated potassium channel subunit alpha-1target
DB01110MiconazoleCalcium-activated potassium channel subunit beta-1target
DB01110MiconazoleCalcium-activated potassium channel subunit beta-2target
DB01110MiconazoleCalcium-activated potassium channel subunit beta-3target
DB01110MiconazoleCalcium-activated potassium channel subunit beta-4target
DB01110MiconazoleIntermediate conductance calcium-activated potassium channel protein 4target
DB01110MiconazoleSmall conductance calcium-activated potassium channel protein 1target
DB01110MiconazoleSmall conductance calcium-activated potassium channel protein 2target
DB01110MiconazoleSmall conductance calcium-activated potassium channel protein 3target
DB01110MiconazolePotassium voltage-gated channel subfamily H member 2target
DB01110MiconazolePotassium voltage-gated channel subfamily H member 6target
DB01110MiconazolePotassium voltage-gated channel subfamily H member 7target
DB01110MiconazoleCytochrome P450 11B1, mitochondrialenzyme
DB01110MiconazoleCytochrome P450 2A6enzyme
DB01110MiconazoleCytochrome P450 2B6enzyme
DB01110MiconazoleCytochrome P450 2C19enzyme
DB01110MiconazoleCytochrome P450 2E1enzyme
DB01110MiconazoleNuclear receptor subfamily 1 group I member 2target
DB01110MiconazoleLanosterol 14-alpha demethylaseenzyme
DB01110MiconazoleCytochrome P450 19A1enzyme
DB00317GefitinibEpidermal growth factor receptortarget
DB00317GefitinibCytochrome P450 3A4enzyme
DB00317GefitinibCytochrome P450 2D6enzyme
DB00317GefitinibP-glycoprotein 1transporter
DB00317GefitinibATP-binding cassette sub-family G member 2transporter
DB00317GefitinibCytochrome P450 3A5enzyme
DB00317GefitinibCytochrome P450 1A1enzyme
DB00317GefitinibCytochrome P450 2C9enzyme
DB00317GefitinibCytochrome P450 2C19enzyme
DB00317GefitinibSerum albumincarrier
DB00317GefitinibAlpha-1-acid glycoprotein 1carrier
DB06731SeproxetineCytochrome P450 3A5enzyme
DB06731SeproxetineCytochrome P450 3A7enzyme
DB06731SeproxetineCytochrome P450 2C9enzyme
DB06731SeproxetineCytochrome P450 2C19enzyme
DB06731SeproxetineCytochrome P450 3A4enzyme
DB11753RifamycinCytochrome P450 3A4enzyme
DB11753RifamycinCytochrome P450 2C19enzyme
DB11753RifamycinCytochrome P450 2B6enzyme
DB11753RifamycinCytochrome P450 2C8enzyme
DB11753RifamycinCytochrome P450 2C9enzyme
DB11753RifamycinSolute carrier organic anion transporter family member 1A2transporter
DB11753RifamycinSolute carrier organic anion transporter family member 1B1transporter
DB11753RifamycinSolute carrier organic anion transporter family member 1B3transporter
DB11753RifamycinSolute carrier organic anion transporter family member 2A1transporter
DB11753RifamycinSolute carrier organic anion transporter family member 2B1transporter
DB11753RifamycinSerum albumincarrier
DB11753RifamycinDNA-directed RNA polymerase subunit betatarget
DB11753RifamycinDNA-directed RNA polymerase subunit alphatarget
DB11753RifamycinDNA-directed RNA polymerase subunit beta'target
DB11753RifamycinMultidrug and toxin extrusion protein 1transporter
DB11753RifamycinCytochrome P450 1A2enzyme
DB11753RifamycinP-glycoprotein 1transporter
DB00196FluconazoleCytochrome P450 3A4enzyme
DB00196FluconazoleCytochrome P450 2C9enzyme
DB00196FluconazoleCytochrome P450 2C19enzyme
DB00196FluconazoleP-glycoprotein 1transporter
DB00196FluconazoleCytochrome P450 51target
DB00196FluconazoleCytochrome P450 3A5enzyme
DB12245TriclabendazoleCytochrome P450 1A2enzyme
DB12245TriclabendazoleCytochrome P450 2C9enzyme
DB12245TriclabendazoleExcretory Secretory (ES) proteinstarget
DB12245TriclabendazoleCytochrome P450 3A4enzyme
DB12245TriclabendazoleCytochrome P450 1A1enzyme
DB12245TriclabendazoleCytochrome P450 1B1enzyme
DB12245TriclabendazoleCytochrome P450 2C19enzyme
DB12245TriclabendazoleCytochrome P450 2D6enzyme
DB12245TriclabendazoleCytochrome P450 2A6enzyme
DB12245TriclabendazoleCytochrome P450 2C8enzyme
DB12245TriclabendazoleCytochrome P450 2B6enzyme
DB12015AlpelisibPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoformtarget
DB12015AlpelisibCytochrome P450 3A4enzyme
DB12015AlpelisibCytochrome P450 2C9enzyme
DB12015AlpelisibCytochrome P450 2C8enzyme
DB12015AlpelisibCytochrome P450 2C19enzyme
DB12015AlpelisibATP-binding cassette sub-family G member 2transporter
DB12015AlpelisibP-glycoprotein 1transporter
DB12474LynestrenolCytochrome P450 3A4enzyme
DB12474LynestrenolCytochrome P450 2C9enzyme
DB12474LynestrenolCytochrome P450 2C19enzyme
DB00977EthinylestradiolEstrogen receptor alphatarget
DB00977EthinylestradiolNuclear receptor subfamily 1 group I member 2target
DB00977EthinylestradiolCytochrome P450 3A4enzyme
DB00977EthinylestradiolCytochrome P450 2C8enzyme
DB00977EthinylestradiolBile salt export pumptransporter
DB00977EthinylestradiolSodium/bile acid cotransportertransporter
DB00977EthinylestradiolCanalicular multispecific organic anion transporter 1transporter
DB00977EthinylestradiolP-glycoprotein 1transporter
DB00977EthinylestradiolSex hormone-binding globulintarget
DB00977EthinylestradiolUDP-glucuronosyltransferase 1-1enzyme
DB00977EthinylestradiolCytochrome P450 2C19enzyme
DB06730GestodeneCytochrome P450 3A5enzyme
DB06730GestodeneCytochrome P450 3A7enzyme
DB06730GestodeneProgesterone receptortarget
DB06730GestodeneCytochrome P450 3A4enzyme
DB06730GestodeneCytochrome P450 2C19enzyme
DB00715ParoxetineSodium-dependent serotonin transportertarget
DB00715ParoxetineSodium-dependent noradrenaline transportertarget
DB00715Paroxetine5-hydroxytryptamine receptor 2Atarget
DB00715ParoxetineCytochrome P450 2D6enzyme
DB00715ParoxetineCytochrome P450 2C9enzyme
DB00715ParoxetineP-glycoprotein 1transporter
DB00715ParoxetineCytochrome P450 2B6enzyme
DB00715ParoxetineCytochrome P450 1A2enzyme
DB00715ParoxetineCytochrome P450 3A4enzyme
DB00715ParoxetineAlpha-1 adrenergic receptorstarget
DB00715ParoxetineAlpha-2 adrenergic receptorstarget
DB00715ParoxetineBeta adrenergic receptortarget
DB00715ParoxetineDopamine D2 receptortarget
DB00715ParoxetineHistamine H1 receptortarget
DB00715ParoxetineSerotonin Receptorstarget
DB00715ParoxetineMuscarinic acetylcholine receptortarget
DB00715Paroxetine5-hydroxytryptamine receptor 2Btarget
DB00715ParoxetineD(1) dopamine receptortarget
DB00715ParoxetineCytochrome P450 2C19enzyme
DB00673AprepitantNeurokinin 1 receptortarget
DB00673AprepitantCytochrome P450 3A4enzyme
DB00673AprepitantCytochrome P450 2C9enzyme
DB00673AprepitantCytochrome P450 2C19enzyme
DB06442AvasimibeLiver carboxylesterase 1target
DB06442AvasimibeCytochrome P450 3A4enzyme
DB06442AvasimibeCytochrome P450 2C9enzyme
DB06442AvasimibeCytochrome P450 1A2enzyme
DB06442AvasimibeCytochrome P450 2C19enzyme
DB14635Curcumin sulfatePeroxisome proliferator-activated receptor gammatarget
DB14635Curcumin sulfateVitamin D3 receptortarget
DB14635Curcumin sulfateMultidrug resistance-associated protein 5target
DB14635Curcumin sulfateCarbonyl reductase [NADPH] 1target
DB14635Curcumin sulfateGlutathione S-transferase Ptarget
DB14635Curcumin sulfateCytochrome P450 2C9enzyme
DB14635Curcumin sulfateCytochrome P450 2B6enzyme
DB14635Curcumin sulfateCytochrome P450 1A2enzyme
DB14635Curcumin sulfateCytochrome P450 2D6enzyme
DB14635Curcumin sulfateP-glycoprotein 1transporter
DB14635Curcumin sulfateCytochrome P450 3A4enzyme
DB14635Curcumin sulfateCytochrome P450 3A5enzyme
DB14635Curcumin sulfateUDP-glucuronosyltransferases (UGTs)enzyme
DB14635Curcumin sulfateCytochrome P450 2C19enzyme
DB14635Curcumin sulfateSulfotransferase 1A3/1A4enzyme
DB14635Curcumin sulfateSulfotransferase family cytosolic 1B member 1enzyme
DB14635Curcumin sulfateEstrogen sulfotransferaseenzyme
DB14635Curcumin sulfateSulfotransferase 1C4enzyme
DB14575EslicarbazepineUDP-glucuronosyltransferase 1-1enzyme
DB14575EslicarbazepineCytochrome P450 2C19enzyme
DB14575EslicarbazepineP2X purinoceptor 4target
DB14575EslicarbazepineCytochrome P450 3A4enzyme
DB15444ElexacaftorSolute carrier organic anion transporter family member 1B1transporter
DB15444ElexacaftorSolute carrier organic anion transporter family member 1B3transporter
DB15444ElexacaftorP-glycoprotein 1transporter
DB15444ElexacaftorSerum albumincarrier
DB15444ElexacaftorCytochrome P450 3A4enzyme
DB15444ElexacaftorCytochrome P450 3A5enzyme
DB15444ElexacaftorCytochrome P450 1A2enzyme
DB15444ElexacaftorCytochrome P450 2B6enzyme
DB15444ElexacaftorCytochrome P450 2C8enzyme
DB15444ElexacaftorCytochrome P450 2C9enzyme
DB15444ElexacaftorCytochrome P450 2C19enzyme
DB15444ElexacaftorCytochrome P450 2D6enzyme
DB15444ElexacaftorCystic fibrosis transmembrane conductance regulatortarget