Cytochrome P-450 CYP3A5 Inhibitors (strength unknown)

DrugDrug NameDrug Description
DB00091CyclosporineA steroid-sparing immunosuppressant used in organ and bone marrow transplants as well as inflammatory conditions such as ulcerative colitis, rheumatoid arthritis, and atopic dermatitis.
DB01232SaquinavirAn HIV protease inhibitor used in combination with other antiretroviral agents for the treatment of HIV-1 with advanced immunodeficiency.
DB00619ImatinibA tyrosine kinase inhibitor used to treat a number of leukemias, myelodysplastic/myeloproliferative disease, systemic mastocytosis, hypereosinophilic syndrome, dermatofibrosarcoma protuberans, and gastrointestinal stromal tumors.
DB00976TelithromycinAn ketolide used to treat community acquired pneumonia of mild to moderate severity.
DB00673AprepitantA substance P/neurokinin 1 receptor antagonist used to treat nausea and vomiting caused by chemotherapy and surgery.
DB00446ChloramphenicolA broad spectrum antibiotic that is effective against a variety of susceptible and serious bacterial infections but is not frequently used because of its high risk of bone marrow toxicity.
DB00705DelavirdineA non-nucleoside reverse transcriptase inhibitor used to treat HIV infection.
DB06730GestodeneGestodene is a progestogen hormonal contraceptive. Products containing gestoden include Meliane, which contains 20 mcg of ethinylestradiol and 75 mcg of gestodene; and Gynera, which contains 30 mcg of ethinylestradiol...
DB01388MibefradilFor the treatment of angina and high blood pressure.
DB06731SeproxetineSeproxetine is also known as (S)-norfluoxetine. It is a selective serotonin reuptake inhibitor (SSRI). It is an active metabolite of fluoxetine. Seproxetine was being investigated by Eli Lilly as an...
DB00582VoriconazoleA triazole compound used to treat fungal infections.
DB00780PhenelzineA monoamine oxidase inhibitor used to treat atypical, nonendogenous, or neurotic depression.
DB01098RosuvastatinAn HMG-CoA reductase inhibitor used to lower lipid levels and reduce the risk of cardiovascular disease including myocardial infarction and stroke.
DB00588Fluticasone propionateA glucocorticoid used to treat asthma, inflammatory pruritic dermatoses, and nonallergic rhinitis.
DB08865CrizotinibA receptor tyrosine kinase inhibitor used to treat metastatic non-small cell lung cancer (NSCLC) where the tumors have been confirmed to be anaplastic lymphoma kinase (ALK), or ROS1-positive.
DB09054IdelalisibAn antineoplastic kinase inhibitor used to treat chronic lymphocytic leukemia (CLL), relapsed follicular B-cell non-Hodgkin lymphoma (FL), and relapsed small lymphocytic lymphoma (SLL).
DB06412OxymetholoneAn anabolic steroid used for the treatment of types of anemia, such as acquired aplastic anemia, congenital aplastic anemia, myelofibrosis, and the hypoplastic anemias.
DB11574ElbasvirAn antiviral and NS5A inhibitor used to treat hepatitis C infections.
DB12332RucaparibAn anti-cancer agent used to treat recurrent ovarian, fallopian tube, or peritoneal cancer.
DB12070LetermovirAn antiviral medication used to treat CMV infections and disease in adult CMV-seropositive recipients of an allogeneic hematopoietic stem cell transplant (HSCT).
DB06654SafinamideA MAO-B inhibitor used as an add-on treatment to levodopa/carbidopa for Parkinson's disease during "off" episodes.
DB00197TroglitazoneFor the treatment of Type II diabetes mellitus. It is used alone or in combination with a sulfonylurea, metformin, or insulin as an adjunct to diet and exercise.
DB06287TemsirolimusA antineoplastic agent used in the treatment of renal cell carcinoma (RCC) that works by inhibiting mTOR.
DB00199ErythromycinA macrolide antibiotic used to treat and prevent a variety of bacterial infections.
DB13867FluticasoneFluticasone's 2 esters are indicated as inhalers for the treatment and management of asthma by prophylaxis[FDA Label] as well as inflammatory and pruritic dermatoses . A DB00588 nasal spray is...
DB08906Fluticasone furoateAn inhaled corticosteroid that can be used as maintenance treatment of asthma and/or chronic obstructive pulmonary disease (COPD) depending on the product. Also available as a nasal spray to manage symptoms of allergic rhinitis.
DB02520DitiocarbA chelating agent that has been used to mobilize toxic metals from the tissues of man and experimental animals. It is the main metabolite of DISULFIRAM.
DB00622NicardipineA calcium channel blocker used for the short-term treatment of hypertension and chronic stable angina.
DB09061CannabidiolAn active cannabinoid used as an adjunctive treatment for the management of seizures associated with Lennox-Gastaut syndrome or Dravet syndrome and symptomatic relief of moderate to severe neuropathic pain or other painful conditions, like cancer.
DB14009Medical CannabisThe use of the plant species Cannabis sativa and Cannabis indica, popularly known as marijuana, has gained popularity in recent years for the management of a wide variety of medical...
DB14011NabiximolsIn Canada, Sativex has received a Notice of Compliance (NOC) for use as an as adjunctive treatment for symptomatic relief of spasticity in patients with multiple sclerosis (MS) who have...
DB14635Curcumin sulfateNo approved therapeutic indications.
DB00776OxcarbazepineAn anti-epileptic used in the treatment of partial-onset seizures.
DB04855DronedaroneAn antiarrhythmic agent used in the reduce the risk of hospitalization in patients with paroxysmal or persistent atrial fibrillation.
DrugDrug NameTargetType
DB00091CyclosporineCalcium signal-modulating cyclophilin ligandtarget
DB00091CyclosporinePeptidyl-prolyl cis-trans isomerase Atarget
DB00091CyclosporineCalcineurin subunit B type 2target
DB00091CyclosporineCytochrome P450 3A5enzyme
DB00091CyclosporineCytochrome P450 3A4enzyme
DB00091CyclosporineCytochrome P450 3A7enzyme
DB00091CyclosporineP-glycoprotein 1transporter
DB00091CyclosporineCanalicular multispecific organic anion transporter 2transporter
DB00091CyclosporineBile salt export pumptransporter
DB00091CyclosporineSolute carrier organic anion transporter family member 1A2transporter
DB00091CyclosporineIleal sodium/bile acid cotransportertransporter
DB00091CyclosporineSodium/bile acid cotransportertransporter
DB00091CyclosporineSolute carrier family 22 member 6transporter
DB00091CyclosporineMultidrug resistance-associated protein 7transporter
DB00091CyclosporineCanalicular multispecific organic anion transporter 1transporter
DB00091CyclosporineATP-binding cassette sub-family G member 2transporter
DB00091CyclosporineSolute carrier organic anion transporter family member 1B1transporter
DB00091CyclosporineCytochrome P450 2C19enzyme
DB00091CyclosporineCytochrome P450 2C9enzyme
DB00091CyclosporineCytochrome P450 2D6enzyme
DB00091CyclosporinePeptidyl-prolyl cis-trans isomerase F, mitochondrialtarget
DB00091CyclosporineSolute carrier organic anion transporter family member 1B3transporter
DB01232SaquinavirHuman immunodeficiency virus type 1 proteasetarget
DB01232SaquinavirCytochrome P450 3A4enzyme
DB01232SaquinavirCytochrome P450 3A5enzyme
DB01232SaquinavirAlpha-1-acid glycoprotein 1carrier
DB01232SaquinavirSerum albumincarrier
DB01232SaquinavirCytochrome P450 3A7enzyme
DB01232SaquinavirP-glycoprotein 1transporter
DB01232SaquinavirSolute carrier family 22 member 1transporter
DB01232SaquinavirSolute carrier organic anion transporter family member 1A2transporter
DB01232SaquinavirATP-binding cassette sub-family G member 2transporter
DB01232SaquinavirSolute carrier organic anion transporter family member 1B1transporter
DB01232SaquinavirMultidrug resistance-associated protein 1transporter
DB01232SaquinavirCanalicular multispecific organic anion transporter 1transporter
DB01232SaquinavirCytochrome P450 2C8enzyme
DB01232SaquinavirCytochrome P450 2D6enzyme
DB01232SaquinavirSolute carrier organic anion transporter family member 2B1transporter
DB01232SaquinavirBile salt export pumptransporter
DB00619ImatinibPlatelet-derived growth factor receptor betatarget
DB00619ImatinibTyrosine-protein kinase ABL1target
DB00619ImatinibMast/stem cell growth factor receptor Kittarget
DB00619ImatinibRET proto-oncogenetarget
DB00619ImatinibHigh affinity nerve growth factor receptortarget
DB00619ImatinibMacrophage colony-stimulating factor 1 receptortarget
DB00619ImatinibPlatelet-derived growth factor receptor alphatarget
DB00619ImatinibEpithelial discoidin domain-containing receptor 1target
DB00619ImatinibCytochrome P450 3A4enzyme
DB00619ImatinibBreakpoint cluster region proteintarget
DB00619ImatinibCytochrome P450 1A2enzyme
DB00619ImatinibCytochrome P450 2D6enzyme
DB00619ImatinibCytochrome P450 2C9enzyme
DB00619ImatinibCytochrome P450 2C19enzyme
DB00619ImatinibCytochrome P450 3A5enzyme
DB00619ImatinibCytochrome P450 3A7enzyme
DB00619ImatinibSolute carrier family 22 member 1transporter
DB00619ImatinibP-glycoprotein 1transporter
DB00619ImatinibSolute carrier family 22 member 2transporter
DB00619ImatinibATP-binding cassette sub-family G member 2transporter
DB00619ImatinibATP-binding cassette sub-family A member 3transporter
DB00619ImatinibProstaglandin G/H synthase 1enzyme
DB00619ImatinibSerum albumincarrier
DB00619ImatinibAlpha-1-acid glycoprotein 1carrier
DB00619ImatinibBile salt export pumptransporter
DB00619ImatinibCytochrome P450 2C8enzyme
DB00976Telithromycin23S ribosomal RNAtarget
DB00976TelithromycinCytochrome P450 3A4enzyme
DB00976TelithromycinSolute carrier organic anion transporter family member 1B1transporter
DB00976TelithromycinSolute carrier organic anion transporter family member 1B3transporter
DB00673AprepitantNeurokinin 1 receptortarget
DB00673AprepitantCytochrome P450 3A4enzyme
DB00673AprepitantCytochrome P450 2C9enzyme
DB00673AprepitantCytochrome P450 2C19enzyme
DB00446ChloramphenicolComplement decay-accelerating factortarget
DB00446ChloramphenicolDr hemagglutinin structural subunittarget
DB00446ChloramphenicolCytochrome P450 2C19enzyme
DB00446ChloramphenicolCytochrome P450 3A4enzyme
DB00446ChloramphenicolCytochrome P450 3A5enzyme
DB00446ChloramphenicolCytochrome P450 3A7enzyme
DB00446ChloramphenicolSolute carrier family 22 member 6transporter
DB00446Chloramphenicol50S ribosomal protein L16target
DB00446ChloramphenicolChloramphenicol acetyltransferase 3enzyme
DB00446ChloramphenicolChloramphenicol acetyltransferaseenzyme
DB00446ChloramphenicolChloramphenicol 3-O phosphotransferaseenzyme
DB00705DelavirdineCytochrome P450 3A4enzyme
DB00705DelavirdineCytochrome P450 2C9enzyme
DB00705DelavirdineCytochrome P450 2D6enzyme
DB00705DelavirdineCytochrome P450 3A5enzyme
DB00705DelavirdineCytochrome P450 3A7enzyme
DB00705DelavirdineCytochrome P450 2C19enzyme
DB00705DelavirdineReverse transcriptase/RNaseHtarget
DB06730GestodeneCytochrome P450 3A5enzyme
DB06730GestodeneCytochrome P450 3A7enzyme
DB06730GestodeneProgesterone receptortarget
DB06730GestodeneCytochrome P450 3A4enzyme
DB06730GestodeneCytochrome P450 2C19enzyme
DB01388MibefradilVoltage-dependent T-type calcium channel subunit alpha-1Gtarget
DB01388MibefradilVoltage-dependent T-type calcium channel subunit alpha-1Htarget
DB01388MibefradilVoltage-dependent L-type calcium channel subunit alpha-1Ctarget
DB01388MibefradilVoltage-dependent L-type calcium channel subunit beta-1target
DB01388MibefradilCytochrome P450 3A4enzyme
DB01388MibefradilCytochrome P450 1A2enzyme
DB01388MibefradilCytochrome P450 2D6enzyme
DB01388MibefradilCytochrome P450 3A5enzyme
DB01388MibefradilCytochrome P450 3A7enzyme
DB01388MibefradilP-glycoprotein 1transporter
DB01388MibefradilVoltage-dependent T-type calcium channel subunit alpha-1Itarget
DB01388MibefradilVoltage-dependent L-type calcium channel subunit alpha-1Starget
DB01388MibefradilVoltage-dependent L-type calcium channel subunit alpha-1Ftarget
DB01388MibefradilVoltage-dependent L-type calcium channel subunit alpha-1Dtarget
DB01388MibefradilVoltage-dependent L-type calcium channel subunit beta-2target
DB01388MibefradilVoltage-dependent L-type calcium channel subunit beta-3target
DB01388MibefradilVoltage-dependent L-type calcium channel subunit beta-4target
DB01388MibefradilCytochrome P450 11B1, mitochondrialenzyme
DB01388MibefradilCytochrome P450 11B2, mitochondrialenzyme
DB06731SeproxetineCytochrome P450 3A5enzyme
DB06731SeproxetineCytochrome P450 3A7enzyme
DB06731SeproxetineCytochrome P450 2C9enzyme
DB06731SeproxetineCytochrome P450 2C19enzyme
DB06731SeproxetineCytochrome P450 3A4enzyme
DB00582VoriconazoleCytochrome P450 2C19enzyme
DB00582VoriconazoleCytochrome P450 3A4enzyme
DB00582VoriconazoleCytochrome P450 2C9enzyme
DB00582VoriconazoleDimethylaniline monooxygenase [N-oxide-forming] 1enzyme
DB00582VoriconazoleDimethylaniline monooxygenase [N-oxide-forming] 3enzyme
DB00582VoriconazoleCytochrome P450 3A5enzyme
DB00582VoriconazoleCytochrome P450 3A7enzyme
DB00582VoriconazoleProstaglandin G/H synthase 1enzyme
DB00582VoriconazoleCytochrome P450 51target
DB00582VoriconazoleCytochrome P450 2B6enzyme
DB00780PhenelzineMembrane primary amine oxidasetarget
DB00780PhenelzineAmine oxidase [flavin-containing] Btarget
DB00780PhenelzineAmine oxidase [flavin-containing] Atarget
DB00780PhenelzineAmine oxidase [flavin-containing] Aenzyme
DB00780PhenelzineAmine oxidase [flavin-containing] Benzyme
DB00780PhenelzineCytochrome P450 2E1enzyme
DB00780Phenelzine4-aminobutyrate aminotransferase, mitochondrialtarget
DB00780PhenelzineGlutamic acid decarboxylasetarget
DB00780PhenelzineAlanine aminotransferase 1target
DB00780PhenelzineAlanine aminotransferase 2target
DB00780PhenelzineCytochrome P450 2C19enzyme
DB00780PhenelzineCytochrome P450 2C8enzyme
DB00780PhenelzineCytochrome P450 3A4enzyme
DB00780PhenelzineCytochrome P450 3A5enzyme
DB00780PhenelzineCytochrome P450 3A7enzyme
DB00780PhenelzineCytochrome P450 2D6enzyme
DB00780PhenelzineCytochrome P450 3A Subfamilyenzyme
DB01098Rosuvastatin3-hydroxy-3-methylglutaryl-coenzyme A reductasetarget
DB01098RosuvastatinCytochrome P450 2C9enzyme
DB01098RosuvastatinMultidrug resistance-associated protein 4transporter
DB01098RosuvastatinSolute carrier organic anion transporter family member 1A2transporter
DB01098RosuvastatinSolute carrier organic anion transporter family member 1B3transporter
DB01098RosuvastatinSolute carrier organic anion transporter family member 2B1transporter
DB01098RosuvastatinCystine/glutamate transportertransporter
DB01098RosuvastatinSolute carrier organic anion transporter family member 1B1transporter
DB01098RosuvastatinBile salt export pumptransporter
DB01098RosuvastatinATP-binding cassette sub-family G member 2transporter
DB01098RosuvastatinSerum albumincarrier
DB01098RosuvastatinCanalicular multispecific organic anion transporter 1transporter
DB01098RosuvastatinSolute carrier family 22 member 8transporter
DB01098RosuvastatinSodium/bile acid cotransportertransporter
DB01098RosuvastatinIntegrin alpha-Ltarget
DB00588Fluticasone propionateCorticosteroid-binding globulincarrier
DB00588Fluticasone propionateCytosolic phospholipase A2target
DB00588Fluticasone propionateGlucocorticoid receptortarget
DB00588Fluticasone propionateCytochrome P450 3A4enzyme
DB00588Fluticasone propionateProgesterone receptortarget
DB00588Fluticasone propionateMineralocorticoid receptortarget
DB00588Fluticasone propionateCytochrome P450 3A5enzyme
DB00588Fluticasone propionateCytochrome P450 3A7enzyme
DB00588Fluticasone propionateCytochrome P450 2C8enzyme
DB00588Fluticasone propionateP-glycoprotein 1carrier
DB00588Fluticasone propionateSolute carrier organic anion transporter family member 1B1carrier
DB08865CrizotinibCytochrome P450 3A4enzyme
DB08865CrizotinibCytochrome P450 3A5enzyme
DB08865CrizotinibP-glycoprotein 1transporter
DB08865CrizotinibALK tyrosine kinase receptortarget
DB08865CrizotinibHepatocyte growth factor receptortarget
DB08865CrizotinibCytochrome P450 2B6enzyme
DB08865CrizotinibCytochrome P450 3A Subfamilyenzyme
DB09054IdelalisibPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoformtarget
DB09054IdelalisibATP-binding cassette sub-family G member 2transporter
DB09054IdelalisibP-glycoprotein 1transporter
DB09054IdelalisibAldehyde oxidaseenzyme
DB09054IdelalisibUDP-glucuronosyltransferase 1-4enzyme
DB09054IdelalisibUDP-glucuronosyltransferase 1-4enzyme
DB09054IdelalisibCytochrome P450 2C8enzyme
DB09054IdelalisibCytochrome P450 2C19enzyme
DB09054IdelalisibCytochrome P450 2B6enzyme
DB09054IdelalisibCytochrome P450 3A4enzyme
DB09054IdelalisibSolute carrier organic anion transporter family member 1B1transporter
DB09054IdelalisibSolute carrier organic anion transporter family member 1B3transporter
DB09054IdelalisibCytochrome P450 3A5enzyme
DB09054IdelalisibCytochrome P450 3A43enzyme
DB09054IdelalisibCytochrome P450 3A7enzyme
DB06412OxymetholoneAndrogen receptortarget
DB06412OxymetholoneSerum albumincarrier
DB06412OxymetholoneSex hormone-binding globulincarrier
DB06412OxymetholoneNatriuretic peptides Btarget
DB06412OxymetholoneAmine oxidase [flavin-containing] Aenzyme
DB06412OxymetholoneCytochrome P450 2D6enzyme
DB06412Oxymetholone3-oxo-5-alpha-steroid 4-dehydrogenase 1enzyme
DB06412OxymetholoneCytochrome P450 3A4enzyme
DB06412OxymetholoneCytochrome P450 3A5enzyme
DB06412OxymetholoneCytochrome P450 3A7enzyme
DB06412OxymetholoneCytochrome P450 3A43enzyme
DB11574ElbasvirNonstructural protein 5Atarget
DB11574ElbasvirP-glycoprotein 1transporter
DB11574ElbasvirCytochrome P450 3A4enzyme
DB11574ElbasvirCytochrome P450 3A5enzyme
DB11574ElbasvirCytochrome P450 3A7enzyme
DB11574ElbasvirCytochrome P450 3A43enzyme
DB12332RucaparibPoly [ADP-ribose] polymerase 1target
DB12332RucaparibPoly [ADP-ribose] polymerase 2target
DB12332RucaparibPoly [ADP-ribose] polymerase 3target
DB12332RucaparibCytochrome P450 2D6enzyme
DB12332RucaparibCytochrome P450 1A2enzyme
DB12332RucaparibCytochrome P450 3A4enzyme
DB12332RucaparibP-glycoprotein 1transporter
DB12332RucaparibATP-binding cassette sub-family G member 2transporter
DB12332RucaparibMultidrug and toxin extrusion protein 1transporter
DB12332RucaparibMultidrug and toxin extrusion protein 2transporter
DB12332RucaparibSolute carrier family 22 member 1transporter
DB12332RucaparibMultidrug resistance-associated protein 4transporter
DB12332RucaparibSolute carrier organic anion transporter family member 1B1transporter
DB12332RucaparibSolute carrier organic anion transporter family member 1B3transporter
DB12332RucaparibSolute carrier family 22 member 6transporter
DB12332RucaparibSolute carrier family 22 member 8transporter
DB12332RucaparibCytochrome P450 3A5enzyme
DB12332RucaparibCytochrome P450 3A7enzyme
DB12332RucaparibCytochrome P450 3A43enzyme
DB12332RucaparibCytochrome P450 2C19enzyme
DB12332RucaparibCytochrome P450 2C9enzyme
DB12332RucaparibCytochrome P450 2C8enzyme
DB12332RucaparibUDP-glucuronosyltransferase 1-1enzyme
DB12070LetermovirUDP-glucuronosyltransferase 1-1enzyme
DB12070LetermovirUDP-glucuronosyltransferase 1-3enzyme
DB12070LetermovirSolute carrier organic anion transporter family member 1B1transporter
DB12070LetermovirSolute carrier organic anion transporter family member 1B3transporter
DB12070LetermovirTripartite terminase subunit 1target
DB12070LetermovirTripartite terminase subunit 2target
DB12070LetermovirTripartite terminase subunit 3target
DB12070LetermovirCytochrome P450 2D6enzyme
DB12070LetermovirCytochrome P450 2C8enzyme
DB12070LetermovirCytochrome P450 2C19enzyme
DB12070LetermovirCytochrome P450 2C9enzyme
DB12070LetermovirCytochrome P450 2B6enzyme
DB12070LetermovirP-glycoprotein 1transporter
DB12070LetermovirATP-binding cassette sub-family G member 2transporter
DB12070LetermovirBile salt export pumptransporter
DB12070LetermovirSolute carrier family 22 member 8transporter
DB12070LetermovirCanalicular multispecific organic anion transporter 1transporter
DB12070LetermovirCytochrome P450 3A4enzyme
DB12070LetermovirCytochrome P450 3A5enzyme
DB12070LetermovirCytochrome P450 3A7enzyme
DB12070LetermovirCytochrome P450 3A43enzyme
DB06654SafinamideAmine oxidase [flavin-containing] Btarget
DB06654SafinamideAmine oxidase [flavin-containing] Aenzyme
DB06654SafinamideATP-binding cassette sub-family G member 2transporter
DB06654SafinamideSolute carrier organic anion transporter family member 3A1transporter
DB06654SafinamideCytochrome P450 3A4enzyme
DB06654SafinamideCytochrome P450 1A1enzyme
DB06654SafinamideCytochrome P450 1A2enzyme
DB06654SafinamideCytochrome P450 2B6enzyme
DB06654SafinamideCytochrome P450 2C9enzyme
DB06654SafinamideCytochrome P450 2D6enzyme
DB06654SafinamideCytochrome P450 2C19enzyme
DB06654SafinamideCytochrome P450 2E1enzyme
DB06654SafinamideCytochrome P450 3A5enzyme
DB00197TroglitazonePeroxisome proliferator-activated receptor gammatarget
DB00197TroglitazoneLong-chain-fatty-acid--CoA ligase 4target
DB00197TroglitazonePlasminogen activator inhibitor 1target
DB00197TroglitazoneEquilibrative nucleoside transporter 1target
DB00197TroglitazoneCytochrome P450 3A4enzyme
DB00197TroglitazoneCytochrome P450 2C19enzyme
DB00197TroglitazoneUDP-glucuronosyltransferase 1-1enzyme
DB00197TroglitazoneCytochrome P450 2C8enzyme
DB00197TroglitazoneBile salt export pumptransporter
DB00197TroglitazoneSolute carrier organic anion transporter family member 1B1transporter
DB00197TroglitazoneEstrogen-related receptor gammatarget
DB00197TroglitazoneSteroid hormone receptor ERR1target
DB00197TroglitazoneCytochrome P450 19A1enzyme
DB00197TroglitazoneCytochrome P450 1A1enzyme
DB00197TroglitazoneCytochrome P450 2B6enzyme
DB00197TroglitazoneCytochrome P450 2C9enzyme
DB00197TroglitazoneCytochrome P450 3A5enzyme
DB00197TroglitazoneCytochrome P450 3A7enzyme
DB00197TroglitazoneUDP-glucuronosyltransferase 1-3enzyme
DB00197TroglitazoneUDP-glucuronosyltransferase 1-4enzyme
DB00197TroglitazoneUDP-glucuronosyltransferase 1-6enzyme
DB00197TroglitazoneUDP-glucuronosyltransferase 1-7enzyme
DB00197TroglitazoneUDP-glucuronosyltransferase 1-8enzyme
DB00197TroglitazoneUDP-glucuronosyltransferase 1-9enzyme
DB00197TroglitazoneUDP-glucuronosyltransferase 1-10enzyme
DB00197TroglitazoneUDP-glucuronosyltransferase 2B7enzyme
DB00197TroglitazoneUDP-glucuronosyltransferase 2B15enzyme
DB00197TroglitazonePeroxisome proliferator-activated receptor deltatarget
DB00197TroglitazonePeroxisome proliferator-activated receptor alphatarget
DB00197TroglitazoneGlutathione S-transferase Ptarget
DB06287TemsirolimusSerine/threonine-protein kinase mTORtarget
DB06287TemsirolimusCytochrome P450 3A4enzyme
DB06287TemsirolimusCytochrome P450 3A5enzyme
DB06287TemsirolimusCytochrome P450 3A7enzyme
DB06287TemsirolimusCytochrome P450 2D6enzyme
DB06287TemsirolimusP-glycoprotein 1transporter
DB00199Erythromycin23S ribosomal RNAtarget
DB00199ErythromycinCytochrome P450 3A4enzyme
DB00199ErythromycinCytochrome P450 3A7enzyme
DB00199ErythromycinP-glycoprotein 1transporter
DB00199ErythromycinSolute carrier organic anion transporter family member 1B1transporter
DB00199ErythromycinMotilin receptortarget
DB00199ErythromycinPotassium voltage-gated channel subfamily H member 2target
DB00199ErythromycinCytochrome P450 3A5enzyme
DB00199ErythromycinSolute carrier organic anion transporter family member 1B3transporter
DB00199ErythromycinBile salt export pumptransporter
DB00199ErythromycinCanalicular multispecific organic anion transporter 1transporter
DB00199ErythromycinSolute carrier organic anion transporter family member 1A2transporter
DB13867FluticasoneCytochrome P450 3A4enzyme
DB13867FluticasoneCytochrome P450 2C8enzyme
DB13867FluticasoneP-glycoprotein 1carrier
DB13867FluticasoneSolute carrier organic anion transporter family member 1B1carrier
DB13867FluticasoneP-glycoprotein 1transporter
DB13867FluticasoneSolute carrier organic anion transporter family member 1B1transporter
DB13867FluticasoneGlucocorticoid receptortarget
DB13867FluticasoneCorticosteroid-binding globulincarrier
DB13867FluticasoneCytochrome P450 3A5enzyme
DB13867FluticasoneCytochrome P450 3A7enzyme
DB13867FluticasoneProgesterone receptortarget
DB13867FluticasoneCytosolic phospholipase A2target
DB13867FluticasoneMineralocorticoid receptortarget
DB08906Fluticasone furoateCytochrome P450 3A4enzyme
DB08906Fluticasone furoateGlucocorticoid receptortarget
DB08906Fluticasone furoateP-glycoprotein 1transporter
DB08906Fluticasone furoateCytochrome P450 2C8enzyme
DB08906Fluticasone furoateSolute carrier organic anion transporter family member 1B1transporter
DB08906Fluticasone furoateCorticosteroid-binding globulincarrier
DB08906Fluticasone furoateP-glycoprotein 1carrier
DB08906Fluticasone furoateSolute carrier organic anion transporter family member 1B1carrier
DB08906Fluticasone furoateCytochrome P450 3A5enzyme
DB08906Fluticasone furoateCytochrome P450 3A7enzyme
DB08906Fluticasone furoateProgesterone receptortarget
DB08906Fluticasone furoateMineralocorticoid receptortarget
DB02520DitiocarbCytochrome P450 2E1enzyme
DB02520DitiocarbCytochrome P450 3A4enzyme
DB02520DitiocarbCytochrome P450 3A5enzyme
DB00622NicardipineVoltage-dependent L-type calcium channel subunit alpha-1Ctarget
DB00622NicardipineCytochrome P450 3A4enzyme
DB00622NicardipineCytochrome P450 2C19enzyme
DB00622NicardipineCytochrome P450 2C8enzyme
DB00622NicardipineCytochrome P450 2D6enzyme
DB00622NicardipineCalcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1Btarget
DB00622NicardipineCalcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1Atarget
DB00622NicardipineAlpha-1A adrenergic receptortarget
DB00622NicardipineAlpha-1D adrenergic receptortarget
DB00622NicardipineAlpha-1B adrenergic receptortarget
DB00622NicardipineMuscarinic acetylcholine receptor M1target
DB00622NicardipineMuscarinic acetylcholine receptor M2target
DB00622NicardipineMuscarinic acetylcholine receptor M3target
DB00622NicardipineMuscarinic acetylcholine receptor M4target
DB00622NicardipineMuscarinic acetylcholine receptor M5target
DB00622NicardipineVoltage-dependent calcium channel subunit alpha-2/delta-1target
DB00622NicardipineVoltage-dependent L-type calcium channel subunit beta-2target
DB00622NicardipineVoltage-dependent L-type calcium channel subunit alpha-1Dtarget
DB00622NicardipineCalmodulintarget
DB00622NicardipineP-glycoprotein 1transporter
DB00622NicardipineCytochrome P450 2B6enzyme
DB00622NicardipineCytochrome P450 2E1enzyme
DB00622NicardipineCytochrome P450 3A5enzyme
DB00622NicardipineSolute carrier organic anion transporter family member 1B1transporter
DB00622NicardipineBile salt export pumptransporter
DB00622NicardipineCytochrome P450 2C9enzyme
DB09061CannabidiolCytochrome P450 2C9enzyme
DB09061CannabidiolCytochrome P450 2C19enzyme
DB09061CannabidiolCytochrome P450 2D6enzyme
DB09061CannabidiolCytochrome P450 3A4enzyme
DB09061CannabidiolCannabinoid receptor 1target
DB09061CannabidiolCannabinoid receptor 2target
DB09061CannabidiolG-protein coupled receptor 12target
DB09061CannabidiolGlycine receptor subunit alpha-1target
DB09061CannabidiolGlycine receptor (alpha-1/beta)target
DB09061CannabidiolGlycine receptor subunit alpha-3target
DB09061CannabidiolN-arachidonyl glycine receptortarget
DB09061CannabidiolG-protein coupled receptor 55target
DB09061Cannabidiol5-hydroxytryptamine receptor 1Atarget
DB09061Cannabidiol5-hydroxytryptamine receptor 2Atarget
DB09061CannabidiolNeuronal acetylcholine receptor subunit alpha-7target
DB09061CannabidiolDelta-type opioid receptortarget
DB09061CannabidiolMu-type opioid receptortarget
DB09061CannabidiolPeroxisome proliferator-activated receptor gammatarget
DB09061CannabidiolCytochrome P450 3A5enzyme
DB09061CannabidiolArylalkylamine N-acetyltransferaseenzyme
DB09061CannabidiolCytochrome P450 1A1enzyme
DB09061CannabidiolFatty-acid amide hydrolase 1enzyme
DB09061CannabidiolArachidonate 5-lipoxygenaseenzyme
DB09061CannabidiolArachidonate 15-lipoxygenaseenzyme
DB09061CannabidiolQuinone oxidoreductaseenzyme
DB09061CannabidiolMultidrug resistance-associated protein 1transporter
DB09061CannabidiolATP-binding cassette sub-family G member 2transporter
DB09061CannabidiolEquilibrative nucleoside transporter 1transporter
DB09061CannabidiolTransient receptor potential cation channel subfamily V member 1target
DB09061CannabidiolVoltage-dependent T-type calcium channel subunit alpha-1Gtarget
DB09061CannabidiolVoltage-dependent T-type calcium channel subunit alpha-1Htarget
DB09061CannabidiolVoltage-dependent T-type calcium channel subunit alpha-1Itarget
DB09061CannabidiolTransient receptor potential cation channel subfamily A member 1target
DB09061CannabidiolTransient receptor potential cation channel subfamily M member 8target
DB09061CannabidiolTransient receptor potential cation channel subfamily V member 2target
DB09061CannabidiolTransient receptor potential cation channel subfamily V member 3target
DB09061CannabidiolTransient receptor potential cation channel subfamily V member 4target
DB09061CannabidiolVoltage-dependent anion-selective channel protein 1target
DB09061Cannabidiol5-hydroxytryptamine receptor 3Atarget
DB09061CannabidiolAdenosine receptor A1target
DB09061CannabidiolProstaglandin G/H synthase 1target
DB09061CannabidiolProstaglandin G/H synthase 2target
DB09061CannabidiolAcetyl-CoA acetyltransferase, mitochondrialtarget
DB09061CannabidiolSteroid 17-alpha-hydroxylase/17,20 lyasetarget
DB09061Cannabidiol3-hydroxy-3-methylglutaryl-coenzyme A reductasetarget
DB09061CannabidiolGlutathione reductase, mitochondrialtarget
DB09061CannabidiolGlutathione peroxidase 1target
DB09061CannabidiolIndoleamine 2,3-dioxygenase 1target
DB09061CannabidiolCytochrome P450 1B1target
DB09061CannabidiolNAD(P)H dehydrogenase [quinone] 1target
DB09061CannabidiolCatalasetarget
DB09061CannabidiolCytochrome P450 3A5target
DB09061CannabidiolCytochrome P450 2D6target
DB09061CannabidiolSuperoxide dismutase [Cu-Zn]target
DB09061CannabidiolCytochrome P450 1A2target
DB09061CannabidiolCytochrome P450 3A7target
DB09061CannabidiolArylalkylamine N-acetyltransferasetarget
DB09061CannabidiolN-acylethanolamine-hydrolyzing acid amidasetarget
DB14009Medical CannabisCannabinoid receptor 1target
DB14009Medical CannabisCannabinoid receptor 2target
DB14009Medical CannabisCytochrome P450 2C9enzyme
DB14009Medical CannabisCytochrome P450 2C19enzyme
DB14009Medical CannabisCytochrome P450 2D6enzyme
DB14009Medical CannabisCytochrome P450 3A4enzyme
DB14009Medical CannabisG-protein coupled receptor 12target
DB14009Medical CannabisGlycine receptor subunit alpha-1target
DB14009Medical CannabisGlycine receptor (alpha-1/beta)target
DB14009Medical CannabisGlycine receptor subunit alpha-3target
DB14009Medical CannabisN-arachidonyl glycine receptortarget
DB14009Medical CannabisG-protein coupled receptor 55target
DB14009Medical Cannabis5-hydroxytryptamine receptor 1Atarget
DB14009Medical Cannabis5-hydroxytryptamine receptor 2Atarget
DB14009Medical CannabisNeuronal acetylcholine receptor subunit alpha-7target
DB14009Medical CannabisDelta-type opioid receptortarget
DB14009Medical CannabisMu-type opioid receptortarget
DB14009Medical CannabisPeroxisome proliferator-activated receptor gammatarget
DB14009Medical CannabisCytochrome P450 3A5enzyme
DB14009Medical CannabisCytochrome P450 3A7enzyme
DB14009Medical CannabisCytochrome P450 1A1enzyme
DB14009Medical CannabisCytochrome P450 1A2enzyme
DB14009Medical CannabisCytochrome P450 1B1enzyme
DB14009Medical CannabisArachidonate 5-lipoxygenaseenzyme
DB14009Medical CannabisArachidonate 15-lipoxygenaseenzyme
DB14009Medical CannabisSuperoxide dismutase [Cu-Zn]enzyme
DB14009Medical CannabisMultidrug resistance-associated protein 1transporter
DB14009Medical CannabisATP-binding cassette sub-family G member 2transporter
DB14009Medical CannabisEquilibrative nucleoside transporter 1transporter
DB14009Medical CannabisTransient receptor potential cation channel subfamily V member 1target
DB14009Medical CannabisVoltage-dependent T-type calcium channel subunit alpha-1Gtarget
DB14009Medical CannabisVoltage-dependent T-type calcium channel subunit alpha-1Htarget
DB14009Medical CannabisVoltage-dependent T-type calcium channel subunit alpha-1Itarget
DB14009Medical CannabisTransient receptor potential cation channel subfamily A member 1target
DB14009Medical CannabisTransient receptor potential cation channel subfamily M member 8target
DB14009Medical CannabisTransient receptor potential cation channel subfamily V member 2target
DB14009Medical CannabisTransient receptor potential cation channel subfamily V member 3target
DB14009Medical CannabisTransient receptor potential cation channel subfamily V member 4target
DB14009Medical CannabisVoltage-dependent anion-selective channel protein 1target
DB14009Medical CannabisN-acyl-phosphatidylethanolamine-hydrolyzing phospholipase Dtarget
DB14009Medical CannabisN-acylethanolamine-hydrolyzing acid amidasetarget
DB14009Medical CannabisArylalkylamine N-acetyltransferasetarget
DB14009Medical CannabisPhospholipase A2target
DB14009Medical CannabisSuperoxide dismutase [Cu-Zn]target
DB14009Medical CannabisFatty-acid amide hydrolase 1target
DB14009Medical CannabisCatalasetarget
DB14009Medical CannabisQuinone oxidoreductasetarget
DB14009Medical CannabisSphingomyelin phosphodiesterasetarget
DB14009Medical CannabisGlutathione peroxidase 1target
DB14009Medical CannabisGlutathione reductase, mitochondrialtarget
DB14009Medical Cannabis3-hydroxy-3-methylglutaryl-coenzyme A reductasetarget
DB14009Medical CannabisIndoleamine 2,3-dioxygenase 1target
DB14009Medical CannabisProstaglandin G/H synthase 1target
DB14009Medical CannabisProstaglandin G/H synthase 2target
DB14009Medical CannabisSteroid 17-alpha-hydroxylase/17,20 lyasetarget
DB14009Medical CannabisAcetyl-CoA acetyltransferase, mitochondrialtarget
DB14011NabiximolsCannabinoid receptor 1target
DB14011NabiximolsCannabinoid receptor 2target
DB14011NabiximolsG-protein coupled receptor 12target
DB14011NabiximolsCytochrome P450 2C9enzyme
DB14011NabiximolsCytochrome P450 2C19enzyme
DB14011NabiximolsCytochrome P450 2D6enzyme
DB14011NabiximolsCytochrome P450 3A4enzyme
DB14011NabiximolsGlycine receptor subunit alpha-1target
DB14011NabiximolsGlycine receptor (alpha-1/beta)target
DB14011NabiximolsGlycine receptor subunit alpha-3target
DB14011NabiximolsN-arachidonyl glycine receptortarget
DB14011NabiximolsG-protein coupled receptor 55target
DB14011Nabiximols5-hydroxytryptamine receptor 1Atarget
DB14011Nabiximols5-hydroxytryptamine receptor 2Atarget
DB14011NabiximolsNeuronal acetylcholine receptor subunit alpha-7target
DB14011NabiximolsDelta-type opioid receptortarget
DB14011NabiximolsMu-type opioid receptortarget
DB14011NabiximolsPeroxisome proliferator-activated receptor gammatarget
DB14011NabiximolsCytochrome P450 3A5enzyme
DB14011NabiximolsArachidonate 5-lipoxygenaseenzyme
DB14011NabiximolsArachidonate 15-lipoxygenaseenzyme
DB14011NabiximolsMultidrug resistance-associated protein 1transporter
DB14011NabiximolsATP-binding cassette sub-family G member 2transporter
DB14011NabiximolsEquilibrative nucleoside transporter 1transporter
DB14011NabiximolsTransient receptor potential cation channel subfamily V member 1target
DB14011NabiximolsVoltage-dependent T-type calcium channel subunit alpha-1Gtarget
DB14011NabiximolsVoltage-dependent T-type calcium channel subunit alpha-1Htarget
DB14011NabiximolsVoltage-dependent T-type calcium channel subunit alpha-1Itarget
DB14011NabiximolsTransient receptor potential cation channel subfamily A member 1target
DB14011NabiximolsTransient receptor potential cation channel subfamily M member 8target
DB14011NabiximolsTransient receptor potential cation channel subfamily V member 2target
DB14011NabiximolsTransient receptor potential cation channel subfamily V member 3target
DB14011NabiximolsTransient receptor potential cation channel subfamily V member 4target
DB14011NabiximolsVoltage-dependent anion-selective channel protein 1target
DB14011NabiximolsProstaglandin G/H synthase 1target
DB14011NabiximolsProstaglandin G/H synthase 2target
DB14011NabiximolsAcetyl-CoA acetyltransferase, mitochondrialtarget
DB14011NabiximolsSteroid 17-alpha-hydroxylase/17,20 lyasetarget
DB14011Nabiximols3-hydroxy-3-methylglutaryl-coenzyme A reductasetarget
DB14011NabiximolsGlutathione reductase, mitochondrialtarget
DB14011NabiximolsGlutathione peroxidase 1target
DB14011NabiximolsIndoleamine 2,3-dioxygenase 1target
DB14011NabiximolsArylalkylamine N-acetyltransferasetarget
DB14011NabiximolsCytochrome P450 1B1target
DB14011NabiximolsCytochrome P450 3A5target
DB14011NabiximolsCytochrome P450 2D6target
DB14011NabiximolsCytochrome P450 1A2target
DB14011NabiximolsCytochrome P450 1A1target
DB14011NabiximolsCytochrome P450 3A7target
DB14011NabiximolsQuinone oxidoreductasetarget
DB14011NabiximolsCatalasetarget
DB14011NabiximolsFatty-acid amide hydrolase 1target
DB14011NabiximolsSuperoxide dismutase [Cu-Zn]target
DB14011NabiximolsN-acylethanolamine-hydrolyzing acid amidasetarget
DB14635Curcumin sulfatePeroxisome proliferator-activated receptor gammatarget
DB14635Curcumin sulfateVitamin D3 receptortarget
DB14635Curcumin sulfateMultidrug resistance-associated protein 5target
DB14635Curcumin sulfateCarbonyl reductase [NADPH] 1target
DB14635Curcumin sulfateGlutathione S-transferase Ptarget
DB14635Curcumin sulfateCytochrome P450 2C9enzyme
DB14635Curcumin sulfateCytochrome P450 2B6enzyme
DB14635Curcumin sulfateCytochrome P450 1A2enzyme
DB14635Curcumin sulfateCytochrome P450 2D6enzyme
DB14635Curcumin sulfateP-glycoprotein 1transporter
DB14635Curcumin sulfateCytochrome P450 3A4enzyme
DB14635Curcumin sulfateCytochrome P450 3A5enzyme
DB14635Curcumin sulfateUDP-glucuronosyltransferases (UGTs)enzyme
DB14635Curcumin sulfateCytochrome P450 2C19enzyme
DB14635Curcumin sulfateSulfotransferase 1A3/1A4enzyme
DB14635Curcumin sulfateSulfotransferase family cytosolic 1B member 1enzyme
DB14635Curcumin sulfateEstrogen sulfotransferaseenzyme
DB14635Curcumin sulfateSulfotransferase 1C4enzyme
DB00776OxcarbazepineCytochrome P450 2C19enzyme
DB00776OxcarbazepineCytochrome P450 3A4enzyme
DB00776OxcarbazepineCytochrome P450 3A5enzyme
DB00776OxcarbazepineSerum albumincarrier
DB00776OxcarbazepineP-glycoprotein 1transporter
DB00776OxcarbazepineAldo-keto reductase family 1 member C1enzyme
DB00776OxcarbazepineAldo-keto reductase family 1 member C2enzyme
DB00776OxcarbazepineAldo-keto reductase family 1 member C3enzyme
DB00776OxcarbazepineAldo-keto reductase family 1 member C4enzyme
DB00776OxcarbazepineCarbonyl reductase [NADPH] 1enzyme
DB00776OxcarbazepineCarbonyl reductase [NADPH] 3enzyme
DB00776OxcarbazepineSodium channel proteintarget
DB04855DronedaroneAlpha-1A adrenergic receptortarget
DB04855DronedaroneBeta-1 adrenergic receptortarget
DB04855DronedaroneAlpha-1B adrenergic receptortarget
DB04855DronedaroneAlpha-1D adrenergic receptortarget
DB04855DronedaroneAlpha-2A adrenergic receptortarget
DB04855DronedaroneAlpha-2B adrenergic receptortarget
DB04855DronedaroneAlpha-2C adrenergic receptortarget
DB04855DronedaronePotassium voltage-gated channel subfamily H member 2target
DB04855DronedaroneVoltage-dependent L-type calcium channel subunit alpha-1Ctarget
DB04855DronedaroneVoltage-dependent L-type calcium channel subunit alpha-1Dtarget
DB04855DronedaroneVoltage-dependent L-type calcium channel subunit alpha-1Ftarget
DB04855DronedaroneVoltage-dependent L-type calcium channel subunit alpha-1Starget
DB04855DronedaroneVoltage-dependent L-type calcium channel subunit beta-1target
DB04855DronedaroneVoltage-dependent L-type calcium channel subunit beta-2target
DB04855DronedaroneVoltage-dependent L-type calcium channel subunit beta-3target
DB04855DronedaroneVoltage-dependent L-type calcium channel subunit beta-4target
DB04855DronedaroneCytochrome P450 2D6enzyme
DB04855DronedaroneCytochrome P450 3A4enzyme
DB04855DronedaroneP-glycoprotein 1transporter
DB04855DronedaronePotassium channel subfamily K member 2target
DB04855DronedaroneSerum albumincarrier
DB04855DronedaroneSolute carrier family 22 member 2transporter
DB04855DronedaroneSolute carrier family 22 member 1transporter
DB04855DronedaroneSolute carrier organic anion transporter family member 1B1transporter
DB04855DronedaroneSolute carrier organic anion transporter family member 1B3transporter
DB04855DronedaroneSolute carrier family 22 member 8transporter
DB04855DronedaroneCytochrome P450 3A5enzyme
DB04855DronedaroneCytochrome P450 2J2enzyme
DB04855DronedaroneThyroid hormone receptor alphatarget
DB04855DronedaroneSodium channel protein type 5 subunit alphatarget
DB04855DronedaroneG protein-activated inward rectifier potassium channel 1target
DB04855DronedaronePotassium voltage-gated channel subfamily KQT member 1target
DB04855DronedaroneInward rectifier potassium channeltarget
DB04855DronedaroneSodium/calcium exchanger 1target
DB04855DronedaronePotassium voltage-gated channel subfamily D member 3target