Cytochrome P-450 CYP2B6 Inhibitors (strength unknown)

Name
Cytochrome P-450 CYP2B6 Inhibitors (strength unknown)
Accession Number
DBCAT004517
Description
Not Available
Drugs
DrugDrug Description
NelfinavirA viral protease inhibitor used in the treatment of HIV infection.
SelegilineA monoamine oxidase inhibitor used to treat major depressive disorder and Parkinson's.
AmlodipineA calcium channel blocker used to treat hypertension and angina.
DesipramineA tricyclic antidepressant used in the treatment of depression.
DoxorubicinA medication used to treat various cancers and Kaposi's Sarcoma.
PhencyclidineA hallucinogen formerly used as a veterinary anesthetic, and briefly as a general anesthetic for humans. Phencyclidine is similar to ketamine in structure and in many of its effects. Like...
AzelastineA histamine H1-receptor antagonist used intranasally to treat allergic and vasomotor rhinitis and in an ophthalmic solution to treat allergic conjunctivitis.
ColchicineAn alkaloid used in the symptomatic relief of pain in attacks of gout and to treat the inflammatory symptoms of Familial Mediterranean Fever (FMF).
EthanolFor therapeutic neurolysis of nerves or ganglia for the relief of intractable chronic pain in such conditions as inoperable cancer and trigeminal neuralgia (tic douloureux), in patients for whom neurosurgical...
IsofluraneAn inhaled general anesthetic used in surgery.
MiconazoleAn azole antifungal with broad-spectrum activity used to treat fungal infections affecting the vagina, mouth and skin, including candidiasis.
QuinidineA medication used to restore normal sinus rhythm, treat atrial fibrillation and flutter, and treat ventricular arrhythmias.
RoxithromycinUsed to treat respiratory tract, urinary and soft tissue infections.
SulfaphenazoleFor the treatment bacterial infections.
Nitric OxideA vasodilating agent used in the treatment of hypoxic respiratory failure in premature neonates.
CisplatinA platinum based chemotherapy agent used to treat various sarcomas, carcinomas, lymphomas, and germ cell tumors.
RegorafenibA kinase inhibitor used to treat patients with metastatic colorectal cancer, unresectable, locally advanced, or metastatic gastrointestinal stromal tumors, and hepatocellular carcinoma.
EnzalutamideAn androgen receptor inhibitor used to treat castration-resistant prostate cancer.
QuazepamA long -acting benzodiazepine used to manage insomnia.
CrizotinibA receptor tyrosine kinase inhibitor used to treat metastatic non-small cell lung cancer (NSCLC) where the tumors have been confirmed to be anaplastic lymphoma kinase (ALK), or ROS1-positive.
EnasidenibAn isocitrate dehydrogenase-2 inhibitor used to treat relapsed or refractory acute myeloid leukemia with an isocitrate dehydrogenase-2 mutation.
VoriconazoleA triazole compound used to treat fungal infections.
SafinamideA MAO-B inhibitor used as an add-on treatment to levodopa/carbidopa for Parkinson's disease during "off" episodes.
LenvatinibA receptor tyrosine kinase inhibitor used for the treatment of metastatic thyroid cancer, advanced renal cell carcinoma in combination with everolimus, and unresectable hepatocellular carcinoma.
RifamycinAn antibacterial used to treat traveler's diarrhea.
TriclabendazoleAn anthelmintic drug used to treat fascioliasis.
ParoxetineA selective serotonin reuptake inhibitor used to treat major depressive disorder, panic disorder, OCD, social phobia, generalized anxiety disorder, the vasomotor symptoms of menopause, and premenstrual dysphoric disorder.
PexidartinibAn antitumor agent that is used for the treatment of rare disease tenosynovial giant cell tumors (TGCT) by inhibiting colony-stimulating factor 1 and its receptor.
FluvoxamineA selective serotonin-reuptake inhibitor used to treat obsessive-compulsive disorder.
ModafinilA stimulant used to improve wakefulness in patients with sleep apnea, narcolepsy, or shift work disorder.
Curcumin sulfateNo approved therapeutic indications.
AbemaciclibA medication used to treat HR+ HER2- advanced or metastatic breast cancer.
ElexacaftorA small molecule CFTR corrector used in combination with tezacaftor and ivacaftor for the treatment of cystic fibrosis patients with one F508del-CFTR mutation.
CenobamateA small molecule drug indicated to treat partial onset seizures in adults.
SertralineA selective serotonin reuptake inhibitor (SSRI) indicated to treat major depressive disorder, social anxiety disorder and many other psychiatric conditions.
LopinavirAn HIV-1 protease inhibitor used in combination with ritonavir to treat human immunodeficiency virus (HIV) infection.
RitonavirAn HIV protease inhibitor used in combination with other antivirals in the treatment of HIV infection.
Methylene blueAn oxidation-reduction agent used for the treatment of pediatric and adult patients with acquired methemoglobinemia.
Drugs & Drug Targets
DrugTargetType
NelfinavirHIV-1 proteasetarget
NelfinavirCytochrome P450 2C19enzyme
NelfinavirCytochrome P450 3A4enzyme
NelfinavirCytochrome P450 2B6enzyme
NelfinavirCytochrome P450 3A5enzyme
NelfinavirCytochrome P450 3A7enzyme
NelfinavirP-glycoprotein 1transporter
NelfinavirSolute carrier family 22 member 1transporter
NelfinavirSolute carrier organic anion transporter family member 1A2transporter
NelfinavirATP-binding cassette sub-family G member 2transporter
NelfinavirSolute carrier organic anion transporter family member 1B1transporter
NelfinavirCytochrome P450 2D6enzyme
NelfinavirSerum albumincarrier
NelfinavirUDP-glucuronosyltransferase 1-1enzyme
NelfinavirSolute carrier organic anion transporter family member 1B3transporter
NelfinavirSolute carrier organic anion transporter family member 2B1transporter
NelfinavirBile salt export pumptransporter
NelfinavirCytochrome P450 2C9enzyme
SelegilineAmine oxidase [flavin-containing] Btarget
SelegilineCytochrome P450 2B6enzyme
SelegilineAmine oxidase [flavin-containing] Atarget
SelegilineCytochrome P450 2A6enzyme
SelegilineCytochrome P450 3A4enzyme
SelegilineP-glycoprotein 1transporter
SelegilineCytochrome P450 1A2enzyme
SelegilineCytochrome P450 2C19enzyme
SelegilineCytochrome P450 2C8enzyme
SelegilineCytochrome P450 2C9enzyme
SelegilineCytochrome P450 2D6enzyme
SelegilineCytochrome P450 2E1enzyme
AmlodipineCarbonic anhydrase 1target
AmlodipineCytochrome P450 3A4enzyme
AmlodipineVoltage-dependent L-type calcium channel subunit alpha-1Ctarget
AmlodipineCytochrome P450 1A1enzyme
AmlodipineCytochrome P450 2B6enzyme
AmlodipineVoltage-dependent N-type calcium channel subunit alpha-1Btarget
AmlodipineVoltage-dependent L-type calcium channel subunit beta-1target
AmlodipineVoltage-dependent calcium channel subunit alpha-2/delta-3target
AmlodipineCytochrome P450 3A5enzyme
AmlodipineP-glycoprotein 1transporter
AmlodipineCytochrome P450 2C8enzyme
AmlodipineCytochrome P450 2D6enzyme
AmlodipineSphingomyelin phosphodiesterasetarget
AmlodipineVoltage-dependent T-type calcium channel subunit alpha-1Itarget
AmlodipineVoltage-dependent N-type calcium channeltarget
DesipramineMuscarinic acetylcholine receptor M1target
DesipramineSodium-dependent noradrenaline transportertarget
DesipramineBeta-2 adrenergic receptortarget
DesipramineMuscarinic acetylcholine receptor M2target
DesipramineSodium-dependent serotonin transportertarget
DesipramineHistamine H1 receptortarget
DesipramineBeta-1 adrenergic receptortarget
DesipramineCytochrome P450 2D6enzyme
DesipramineMuscarinic acetylcholine receptor M3target
DesipramineMuscarinic acetylcholine receptor M4target
DesipramineMuscarinic acetylcholine receptor M5target
DesipramineAlpha-1 adrenergic receptorstarget
Desipramine5-hydroxytryptamine receptor 2Atarget
DesipramineAlpha-1-acid glycoprotein 1carrier
DesipramineCytochrome P450 2B6enzyme
DesipramineCytochrome P450 3A4enzyme
DesipramineSolute carrier family 22 member 2transporter
DesipramineSolute carrier family 22 member 1transporter
DesipramineSolute carrier family 22 member 3transporter
DesipramineSolute carrier family 22 member 5transporter
DesipramineP-glycoprotein 1transporter
DesipramineSolute carrier family 22 member 4transporter
DesipramineCytochrome P450 1A2enzyme
DesipramineCytochrome P450 2E1enzyme
DesipramineSphingomyelin phosphodiesterasetarget
Desipramine5-hydroxytryptamine receptor 1Atarget
Desipramine5-hydroxytryptamine receptor 2Ctarget
DesipramineDopamine D2 receptortarget
DesipramineAlpha-2 adrenergic receptorstarget
DoxorubicinDNA topoisomerase 2-alphatarget
DoxorubicinDNAtarget
DoxorubicinCytochrome P450 3A4enzyme
DoxorubicinCytochrome P450 2D6enzyme
DoxorubicinCytochrome P450 2B6enzyme
DoxorubicinP-glycoprotein 1transporter
DoxorubicinCanalicular multispecific organic anion transporter 2transporter
DoxorubicinMultidrug resistance-associated protein 6transporter
DoxorubicinMultidrug resistance-associated protein 1transporter
DoxorubicinMultidrug resistance-associated protein 7transporter
DoxorubicinATP-binding cassette sub-family G member 2transporter
DoxorubicinBile salt export pumptransporter
DoxorubicinSolute carrier family 22 member 16transporter
DoxorubicinATP-binding cassette sub-family B member 8, mitochondrialtransporter
DoxorubicinCytochrome P450 1B1enzyme
DoxorubicinCarbonyl reductase [NADPH] 1enzyme
DoxorubicinCarbonyl reductase [NADPH] 3enzyme
DoxorubicinAlcohol dehydrogenase [NADP(+)]enzyme
DoxorubicinAldo-keto reductase family 1 member C3enzyme
DoxorubicinNAD(P)H dehydrogenase [quinone] 1enzyme
DoxorubicinXanthine dehydrogenase/oxidaseenzyme
DoxorubicinNitric oxide synthase, endothelialenzyme
DoxorubicinNitric oxide synthase, inducibleenzyme
DoxorubicinNitric oxide synthase, brainenzyme
DoxorubicinNADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrialenzyme
DoxorubicinNADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrialenzyme
DoxorubicinNADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrialenzyme
DoxorubicinNADPH--cytochrome P450 reductaseenzyme
DoxorubicinRalA-binding protein 1transporter
DoxorubicinCanalicular multispecific organic anion transporter 1transporter
DoxorubicinSerum albumincarrier
DoxorubicinNucleolar and coiled-body phosphoprotein 1target
PhencyclidineGlutamate receptor ionotropic, NMDA 3Atarget
PhencyclidineSigma non-opioid intracellular receptor 1target
PhencyclidineCytochrome P450 2B6enzyme
AzelastineHistamine H1 receptortarget
AzelastineCytochrome P450 1A2enzyme
AzelastineCytochrome P450 2D6enzyme
AzelastineCytochrome P450 3A4enzyme
AzelastineCytochrome P450 2C19enzyme
AzelastineCytochrome P450 1A1enzyme
AzelastineCytochrome P450 3A5enzyme
AzelastineCytochrome P450 2C9enzyme
AzelastineCytochrome P450 2C8enzyme
AzelastineP-glycoprotein 1transporter
AzelastineCytochrome P450 2A6enzyme
AzelastineCytochrome P450 2E1enzyme
AzelastineHistamine H2 receptortarget
AzelastinePhospholipase A2target
AzelastineLeukotriene C4 synthasetarget
AzelastineCytochrome P450 2B6enzyme
ColchicineTubulin beta chaintarget
ColchicineCytochrome P450 3A4enzyme
ColchicineP-glycoprotein 1transporter
ColchicineCytochrome P450 2B6enzyme
ColchicineCytochrome P450 2C8enzyme
ColchicineCytochrome P450 2E1enzyme
ColchicineSerum albumincarrier
EthanolGamma-aminobutyric acid receptor subunit alpha-1target
EthanolGlutamate receptor ionotropic, NMDA 3Atarget
EthanolGlycine receptor subunit alpha-1target
EthanolGlycine receptor subunit alpha-2target
EthanolCytochrome P450 2E1enzyme
EthanolCytochrome P450 1A1enzyme
EthanolCytochrome P450 1A2enzyme
EthanolCytochrome P450 2B6enzyme
EthanolCytochrome P450 2C19enzyme
EthanolCytochrome P450 2C9enzyme
EthanolCytochrome P450 3A4enzyme
EthanolCytochrome P450 4A11enzyme
EthanolAlcohol dehydrogenase 1Aenzyme
EthanolAlcohol dehydrogenase 1Benzyme
EthanolAlcohol dehydrogenase 1Cenzyme
EthanolAlcohol dehydrogenase class-3enzyme
EthanolVoltage-dependent L-type calcium channel subunit beta-1target
Ethanol5-hydroxytryptamine receptor 3Atarget
EthanolAlcohol dehydrogenase 4enzyme
EthanolGamma-aminobutyric acid receptor subunit alpha-2target
EthanolNeuronal acetylcholine receptor subunit alpha-10target
EthanolVoltage-dependent L-type calcium channel subunit alpha-1Ctarget
EthanolGamma-aminobutyric acid receptor subunit alpha-5target
EthanolGamma-aminobutyric acid receptor subunit alpha-4target
EthanolAlcohol dehydrogenase class 4 mu/sigma chainenzyme
EthanolGamma-aminobutyric acid receptor subunit alpha-3target
EthanolGlutamate receptor 1target
EthanolVoltage-dependent calcium channel gamma-1 subunittarget
EthanolNeuronal acetylcholine receptor subunit alpha-2target
EthanolGamma-aminobutyric acid receptor subunit alpha-6target
EthanolGlutamate receptor 2target
EthanolGlutamate receptor 4target
EthanolGlutamate receptor 3target
EthanolNeuronal acetylcholine receptor subunit alpha-4target
EthanolNeuronal acetylcholine receptor subunit beta-2target
EthanolG protein-activated inward rectifier potassium channel 1target
EthanolG protein-activated inward rectifier potassium channel 2target
EthanolVascular cell adhesion protein 1target
EthanolEquilibrative nucleoside transporter 1target
EthanolG protein-activated inward rectifier potassium channel 4target
EthanolNeuronal acetylcholine receptor subunit alpha-7target
EthanolNeuronal acetylcholine receptor subunit alpha-9target
EthanolGamma-aminobutyric acid receptor subunit beta-1target
EthanolGamma-aminobutyric acid receptor subunit beta-3target
EthanolGamma-aminobutyric acid receptor subunit beta-2target
EthanolVoltage-dependent L-type calcium channel subunit alpha-1Starget
EthanolVoltage-dependent L-type calcium channel subunit alpha-1Dtarget
EthanolAlcohol dehydrogenase 6enzyme
EthanolNeuronal acetylcholine receptor subunit beta-4target
EthanolNeuronal acetylcholine receptor subunit alpha-3target
EthanolNeuronal acetylcholine receptor subunit alpha-5target
EthanolNeuronal acetylcholine receptor subunit alpha-6target
EthanolNeuronal acetylcholine receptor subunit beta-3target
EthanolGamma-aminobutyric acid receptor subunit gamma-1target
EthanolGamma-aminobutyric acid receptor subunit gamma-3target
EthanolGamma-aminobutyric acid receptor subunit epsilontarget
EthanolGamma-aminobutyric acid receptor subunit pitarget
EthanolGamma-aminobutyric acid receptor subunit thetatarget
EthanolGamma-aminobutyric acid receptor subunit deltatarget
EthanolAlcohol dehydrogenase [NADP(+)]enzyme
EthanolEquilibrative nucleoside transporter 2target
Ethanol5-hydroxytryptamine receptor 3Etarget
Ethanol5-hydroxytryptamine receptor 3Btarget
Ethanol5-hydroxytryptamine receptor 3Dtarget
Ethanol5-hydroxytryptamine receptor 3Ctarget
EthanolVoltage-dependent calcium channel gamma-2 subunittarget
EthanolG protein-activated inward rectifier potassium channel 3target
EthanolNeural cell adhesion molecule L1target
IsofluraneCalcium-transporting ATPase type 2C member 1target
IsofluraneATP synthase subunit delta, mitochondrialtarget
IsofluraneGamma-aminobutyric acid receptor subunit alpha-1target
IsofluranePotassium voltage-gated channel subfamily A member 1target
IsofluraneGlutamate receptor 1target
IsofluraneGlycine receptor subunit alpha-1target
IsofluraneCalmodulintarget
IsofluraneCytochrome P450 2E1enzyme
IsofluraneSerum albumincarrier
IsofluraneCytochrome P450 2B6enzyme
IsofluraneNADH-ubiquinone oxidoreductase chain 1enzyme
IsofluraneGABA(A) Receptortarget
IsofluraneNeuronal acetylcholine receptor subunit alpha-4target
IsofluraneNeuronal acetylcholine receptor subunit beta-2target
MiconazoleCytochrome P450 2C9enzyme
MiconazoleCytochrome P450 2D6enzyme
MiconazoleCytochrome P450 3A4enzyme
MiconazoleP-glycoprotein 1transporter
MiconazoleCytochrome P450 51target
MiconazoleNitric oxide synthase, endothelialtarget
MiconazoleNitric oxide synthase, inducibletarget
MiconazoleCytochrome P450 11B1, mitochondrialenzyme
MiconazoleCytochrome P450 2A6enzyme
MiconazoleCytochrome P450 2B6enzyme
MiconazoleCytochrome P450 2C19enzyme
MiconazoleCytochrome P450 2E1enzyme
MiconazoleNuclear receptor subfamily 1 group I member 2target
MiconazoleLanosterol 14-alpha demethylaseenzyme
MiconazoleCytochrome P450 19A1enzyme
MiconazoleCalcium-activated potassium channeltarget
MiconazoleVoltage-gated Potassium Channelstarget
MiconazoleInward rectifier potassium channeltarget
MiconazoleVoltage gated L-type calcium channeltarget
MiconazoleSerum albumincarrier
MiconazoleCytochrome P450 2C8enzyme
QuinidineSodium channel protein type 5 subunit alphatarget
QuinidineAlpha-1-acid glycoprotein 1carrier
QuinidinePotassium voltage-gated channel subfamily H member 2target
QuinidinePotassium channel subfamily K member 1target
QuinidinePotassium channel subfamily K member 6target
QuinidineCytochrome P450 1A2enzyme
QuinidineCytochrome P450 2E1enzyme
QuinidineCytochrome P450 1A1enzyme
QuinidineCytochrome P450 2D6enzyme
QuinidineCytochrome P450 3A4enzyme
QuinidineCytochrome P450 3A7enzyme
QuinidineSolute carrier family 22 member 2transporter
QuinidineSolute carrier family 22 member 1transporter
QuinidineSolute carrier family 22 member 5transporter
QuinidineP-glycoprotein 1transporter
QuinidineSolute carrier organic anion transporter family member 1A2transporter
QuinidineSolute carrier family 22 member 8transporter
QuinidineCanalicular multispecific organic anion transporter 1transporter
QuinidineSolute carrier family 22 member 4transporter
QuinidineSolute carrier organic anion transporter family member 1B1transporter
QuinidineCytochrome P450 2B6enzyme
QuinidineCytochrome P450 2C9enzyme
QuinidineAlpha-1A adrenergic receptortarget
QuinidineAlpha-1B adrenergic receptortarget
QuinidineAlpha-1D adrenergic receptortarget
QuinidineBile salt export pumptransporter
QuinidineCytochrome P450 2C8enzyme
Roxithromycin50S ribosomal protein L10target
RoxithromycinP-glycoprotein 1target
RoxithromycinCytochrome P450 3A4enzyme
RoxithromycinCytochrome P450 2B6enzyme
SulfaphenazoleCytochrome P450 2C9enzyme
SulfaphenazoleCytochrome P450 2B6enzyme
SulfaphenazoleCytochrome P450 2C8enzyme
SulfaphenazoleCytochrome P450 2D6enzyme
SulfaphenazoleDihydropteroate synthasetarget
Nitric OxideGuanylate cyclase soluble subunit alpha-2target
Nitric OxideAldehyde dehydrogenase, mitochondrialenzyme
Nitric OxideCytochrome P450 1A2enzyme
Nitric OxideCytochrome P450 2B6enzyme
Nitric OxideCytochrome P450 3A4enzyme
Nitric OxideMetallothionein-1Atarget
Nitric OxideIndoleamine 2,3-dioxygenase 1target
CisplatinDNAtarget
CisplatinCanalicular multispecific organic anion transporter 2transporter
CisplatinMultidrug resistance-associated protein 5transporter
CisplatinCanalicular multispecific organic anion transporter 1transporter
CisplatinSolute carrier family 22 member 2transporter
CisplatinHigh affinity copper uptake protein 1transporter
CisplatinProbable low affinity copper uptake protein 2transporter
CisplatinMultidrug resistance-associated protein 6transporter
CisplatinP-glycoprotein 1transporter
CisplatinCopper-transporting ATPase 2transporter
CisplatinCopper-transporting ATPase 1transporter
CisplatinProstaglandin G/H synthase 2enzyme
CisplatinMyeloperoxidaseenzyme
CisplatinXanthine dehydrogenase/oxidaseenzyme
CisplatinArylamine N-acetyltransferaseenzyme
CisplatinCytochrome P450 2C9enzyme
CisplatinCytochrome P450 2B6enzyme
CisplatinCholinesteraseenzyme
CisplatinCytochrome P450 4A11enzyme
CisplatinATP-binding cassette sub-family G member 2transporter
CisplatinGlutathione S-transferase theta-1enzyme
CisplatinMetallothionein-1Aenzyme
CisplatinMetallothionein-2enzyme
CisplatinSuperoxide dismutase [Cu-Zn]enzyme
CisplatinGlutathione S-transferase Penzyme
CisplatinNAD(P)H dehydrogenase [quinone] 1enzyme
CisplatinGlutathione S-transferase Mu 1enzyme
CisplatinDNA-3-methyladenine glycosylasetarget
CisplatinAlpha-2-macroglobulintarget
CisplatinSerum albumincarrier
CisplatinSerotransferrintarget
CisplatinCopper transport protein ATOX1target
RegorafenibCytochrome P450 3A4enzyme
RegorafenibUDP-glucuronosyltransferase 1-9enzyme
RegorafenibProto-oncogene tyrosine-protein kinase receptor Rettarget
RegorafenibVascular endothelial growth factor receptor 1target
RegorafenibVascular endothelial growth factor receptor 2target
RegorafenibVascular endothelial growth factor receptor 3target
RegorafenibMast/stem cell growth factor receptor Kittarget
RegorafenibPlatelet-derived growth factor receptor alphatarget
RegorafenibPlatelet-derived growth factor receptor betatarget
RegorafenibFibroblast growth factor receptor 1target
RegorafenibFibroblast growth factor receptor 2target
RegorafenibAngiopoietin-1 receptortarget
RegorafenibDiscoidin domain-containing receptor 2target
RegorafenibHigh affinity nerve growth factor receptortarget
RegorafenibEphrin type-A receptor 2target
RegorafenibRAF proto-oncogene serine/threonine-protein kinasetarget
RegorafenibSerine/threonine-protein kinase B-raftarget
RegorafenibCytochrome P450 2C8enzyme
RegorafenibCytochrome P450 2C9enzyme
RegorafenibCytochrome P450 2B6enzyme
RegorafenibMitogen-activated protein kinase 11target
RegorafenibTyrosine-protein kinase FRKtarget
RegorafenibTyrosine-protein kinase ABL1target
RegorafenibP-glycoprotein 1transporter
RegorafenibATP-binding cassette sub-family G member 2transporter
RegorafenibUDP-glucuronosyltransferase 1-1enzyme
EnzalutamideSerum albumincarrier
EnzalutamideCytochrome P450 2C8enzyme
EnzalutamideCytochrome P450 3A4enzyme
EnzalutamideAndrogen receptortarget
EnzalutamideCytochrome P450 2C9enzyme
EnzalutamideCytochrome P450 2C19enzyme
EnzalutamideCytochrome P450 2B6enzyme
EnzalutamideCytochrome P450 3A5enzyme
EnzalutamideP-glycoprotein 1transporter
EnzalutamideThyroxine-binding globulincarrier
QuazepamCytochrome P450 2C19enzyme
QuazepamCytochrome P450 2C9enzyme
QuazepamCytochrome P450 3A4enzyme
QuazepamGABA(A) Receptortarget
QuazepamCytochrome P450 2B6enzyme
QuazepamGABA(A) Receptor Benzodiazepine Binding Sitetarget
CrizotinibCytochrome P450 3A4enzyme
CrizotinibCytochrome P450 3A5enzyme
CrizotinibP-glycoprotein 1transporter
CrizotinibALK tyrosine kinase receptortarget
CrizotinibHepatocyte growth factor receptortarget
CrizotinibCytochrome P450 2B6enzyme
CrizotinibCytochrome P450 3A Subfamilyenzyme
EnasidenibCytochrome P450 1A2enzyme
EnasidenibCytochrome P450 2B6enzyme
EnasidenibIsocitrate dehydrogenase [NADP], mitochondrialtarget
EnasidenibCytochrome P450 2C8enzyme
EnasidenibCytochrome P450 2C9enzyme
EnasidenibCytochrome P450 2C19enzyme
EnasidenibCytochrome P450 2D6enzyme
EnasidenibCytochrome P450 3A4enzyme
EnasidenibUDP-glucuronosyltransferase 1-1enzyme
EnasidenibUDP-glucuronosyltransferase 1-3enzyme
EnasidenibUDP-glucuronosyltransferase 1-4enzyme
EnasidenibUDP-glucuronosyltransferase 1-9enzyme
EnasidenibUDP-glucuronosyltransferase 2B7enzyme
EnasidenibUDP-glucuronosyltransferase 2B15enzyme
EnasidenibP-glycoprotein 1transporter
EnasidenibATP-binding cassette sub-family G member 2transporter
EnasidenibSolute carrier family 22 member 6transporter
EnasidenibSolute carrier organic anion transporter family member 1B1transporter
EnasidenibSolute carrier family 22 member 2transporter
EnasidenibSolute carrier organic anion transporter family member 1B3transporter
EnasidenibSolute carrier family 22 member 8transporter
VoriconazoleCytochrome P450 2C19enzyme
VoriconazoleCytochrome P450 3A4enzyme
VoriconazoleCytochrome P450 2C9enzyme
VoriconazoleDimethylaniline monooxygenase [N-oxide-forming] 1enzyme
VoriconazoleDimethylaniline monooxygenase [N-oxide-forming] 3enzyme
VoriconazoleCytochrome P450 3A5enzyme
VoriconazoleCytochrome P450 3A7enzyme
VoriconazoleProstaglandin G/H synthase 1enzyme
VoriconazoleCytochrome P450 51target
VoriconazoleCytochrome P450 2B6enzyme
SafinamideAmine oxidase [flavin-containing] Btarget
SafinamideAmine oxidase [flavin-containing] Aenzyme
SafinamideATP-binding cassette sub-family G member 2transporter
SafinamideSolute carrier organic anion transporter family member 3A1transporter
SafinamideCytochrome P450 3A4enzyme
SafinamideCytochrome P450 1A1enzyme
SafinamideCytochrome P450 1A2enzyme
SafinamideCytochrome P450 2B6enzyme
SafinamideCytochrome P450 2C9enzyme
SafinamideCytochrome P450 2D6enzyme
SafinamideCytochrome P450 2C19enzyme
SafinamideCytochrome P450 2E1enzyme
SafinamideCytochrome P450 3A5enzyme
LenvatinibVascular endothelial growth factor receptor 1target
LenvatinibVascular endothelial growth factor receptor 2target
LenvatinibVascular endothelial growth factor receptor 3target
LenvatinibFibroblast growth factor receptor 1target
LenvatinibFibroblast growth factor receptor 2target
LenvatinibFibroblast growth factor receptor 3target
LenvatinibFibroblast growth factor receptor 4target
LenvatinibPlatelet-derived growth factor receptor alphatarget
LenvatinibProto-oncogene tyrosine-protein kinase receptor Rettarget
LenvatinibMast/stem cell growth factor receptor Kittarget
LenvatinibP-glycoprotein 1transporter
LenvatinibATP-binding cassette sub-family G member 2transporter
LenvatinibCytochrome P450 3A4enzyme
LenvatinibAldehyde oxidaseenzyme
LenvatinibCytochrome P450 2C8enzyme
LenvatinibCytochrome P450 2C9enzyme
LenvatinibCytochrome P450 1A2enzyme
LenvatinibCytochrome P450 2B6enzyme
LenvatinibCytochrome P450 2C19enzyme
LenvatinibSolute carrier family 22 member 6transporter
LenvatinibSolute carrier family 22 member 8transporter
LenvatinibSolute carrier family 22 member 2transporter
LenvatinibSolute carrier organic anion transporter family member 1B1transporter
LenvatinibBile salt export pumptransporter
LenvatinibCytochrome P450 2D6enzyme
RifamycinCytochrome P450 3A4enzyme
RifamycinCytochrome P450 2C19enzyme
RifamycinCytochrome P450 2B6enzyme
RifamycinCytochrome P450 2C8enzyme
RifamycinCytochrome P450 2C9enzyme
RifamycinSolute carrier organic anion transporter family member 1A2transporter
RifamycinSolute carrier organic anion transporter family member 1B1transporter
RifamycinSolute carrier organic anion transporter family member 1B3transporter
RifamycinSolute carrier organic anion transporter family member 2A1transporter
RifamycinSolute carrier organic anion transporter family member 2B1transporter
RifamycinSerum albumincarrier
RifamycinDNA-directed RNA polymerase subunit betatarget
RifamycinDNA-directed RNA polymerase subunit alphatarget
RifamycinDNA-directed RNA polymerase subunit beta'target
RifamycinMultidrug and toxin extrusion protein 1transporter
RifamycinCytochrome P450 1A2enzyme
RifamycinP-glycoprotein 1transporter
TriclabendazoleCytochrome P450 1A2enzyme
TriclabendazoleCytochrome P450 2C9enzyme
TriclabendazoleExcretory Secretory (ES) proteinstarget
TriclabendazoleCytochrome P450 3A4enzyme
TriclabendazoleCytochrome P450 1A1enzyme
TriclabendazoleCytochrome P450 1B1enzyme
TriclabendazoleCytochrome P450 2C19enzyme
TriclabendazoleCytochrome P450 2D6enzyme
TriclabendazoleCytochrome P450 2A6enzyme
TriclabendazoleCytochrome P450 2C8enzyme
TriclabendazoleCytochrome P450 2B6enzyme
ParoxetineSodium-dependent serotonin transportertarget
ParoxetineSodium-dependent noradrenaline transportertarget
Paroxetine5-hydroxytryptamine receptor 2Atarget
ParoxetineCytochrome P450 2D6enzyme
ParoxetineCytochrome P450 2C9enzyme
ParoxetineP-glycoprotein 1transporter
ParoxetineCytochrome P450 2B6enzyme
ParoxetineCytochrome P450 1A2enzyme
ParoxetineCytochrome P450 3A4enzyme
ParoxetineAlpha-1 adrenergic receptorstarget
ParoxetineAlpha-2 adrenergic receptorstarget
ParoxetineBeta adrenergic receptortarget
ParoxetineDopamine D2 receptortarget
ParoxetineHistamine H1 receptortarget
ParoxetineSerotonin Receptorstarget
ParoxetineMuscarinic acetylcholine receptortarget
Paroxetine5-hydroxytryptamine receptor 2Btarget
ParoxetineD(1) dopamine receptortarget
ParoxetineCytochrome P450 2C19enzyme
PexidartinibCytochrome P450 3A4enzyme
PexidartinibUDP-glucuronosyltransferase 1-4enzyme
PexidartinibMacrophage colony-stimulating factor 1 receptortarget
PexidartinibCytochrome P450 2B6enzyme
PexidartinibCytochrome P450 2C9enzyme
PexidartinibUDP-glucuronosyltransferase 1-1enzyme
PexidartinibMultidrug and toxin extrusion protein 1transporter
PexidartinibMultidrug and toxin extrusion protein 2transporter
PexidartinibSolute carrier organic anion transporter family member 1B1transporter
PexidartinibSolute carrier organic anion transporter family member 1B3transporter
PexidartinibSolute carrier organic anion transporter family member 2B1transporter
PexidartinibSerum albumincarrier
PexidartinibAlpha-1-acid glycoprotein 1carrier
PexidartinibMast/stem cell growth factor receptor Kittarget
PexidartinibReceptor-type tyrosine-protein kinase FLT3target
PexidartinibPlatelet-derived growth factor receptor betatarget
FluvoxamineSodium-dependent serotonin transportertarget
FluvoxamineCytochrome P450 1A2enzyme
FluvoxamineCytochrome P450 2D6enzyme
FluvoxamineCytochrome P450 2C9enzyme
FluvoxamineCytochrome P450 2C19enzyme
FluvoxamineCytochrome P450 1A1enzyme
FluvoxamineCytochrome P450 3A4enzyme
FluvoxamineCytochrome P450 3A Subfamilyenzyme
FluvoxamineP-glycoprotein 1transporter
FluvoxamineCytochrome P450 2B6enzyme
FluvoxaminePotassium voltage-gated channel subfamily H member 2target
FluvoxamineBile salt export pumptransporter
ModafinilSodium-dependent dopamine transportertarget
ModafinilAlpha-1B adrenergic receptortarget
ModafinilCytochrome P450 3A4enzyme
ModafinilCytochrome P450 2C19enzyme
ModafinilCytochrome P450 1A2enzyme
ModafinilCytochrome P450 2B6enzyme
ModafinilCytochrome P450 2C9enzyme
ModafinilCytochrome P450 3A5enzyme
Curcumin sulfatePeroxisome proliferator-activated receptor gammatarget
Curcumin sulfateVitamin D3 receptortarget
Curcumin sulfateMultidrug resistance-associated protein 5target
Curcumin sulfateCarbonyl reductase [NADPH] 1target
Curcumin sulfateGlutathione S-transferase Ptarget
Curcumin sulfateCytochrome P450 2C9enzyme
Curcumin sulfateCytochrome P450 2B6enzyme
Curcumin sulfateCytochrome P450 1A2enzyme
Curcumin sulfateCytochrome P450 2D6enzyme
Curcumin sulfateP-glycoprotein 1transporter
Curcumin sulfateCytochrome P450 3A4enzyme
Curcumin sulfateCytochrome P450 3A5enzyme
Curcumin sulfateUDP-glucuronosyltransferases (UGTs)enzyme
Curcumin sulfateCytochrome P450 2C19enzyme
Curcumin sulfateSulfotransferase 1A3/1A4enzyme
Curcumin sulfateSulfotransferase family cytosolic 1B member 1enzyme
Curcumin sulfateEstrogen sulfotransferaseenzyme
Curcumin sulfateSulfotransferase 1C4enzyme
AbemaciclibMultidrug and toxin extrusion protein 1transporter
AbemaciclibMultidrug and toxin extrusion protein 2transporter
AbemaciclibCyclin-dependent kinase 4target
AbemaciclibCyclin-dependent kinase 6target
AbemaciclibSerum albumincarrier
Abemaciclibalpha1-acid glycoproteincarrier
AbemaciclibCytochrome P450 3A4enzyme
AbemaciclibP-glycoprotein 1transporter
AbemaciclibATP-binding cassette sub-family G member 2transporter
AbemaciclibSolute carrier family 22 member 2transporter
AbemaciclibCytochrome P450 1A2enzyme
AbemaciclibCytochrome P450 2B6enzyme
AbemaciclibCytochrome P450 2C8enzyme
AbemaciclibCytochrome P450 2C9enzyme
AbemaciclibCytochrome P450 2D6enzyme
ElexacaftorSolute carrier organic anion transporter family member 1B1transporter
ElexacaftorSolute carrier organic anion transporter family member 1B3transporter
ElexacaftorP-glycoprotein 1transporter
ElexacaftorSerum albumincarrier
ElexacaftorCytochrome P450 3A4enzyme
ElexacaftorCytochrome P450 3A5enzyme
ElexacaftorCytochrome P450 1A2enzyme
ElexacaftorCytochrome P450 2B6enzyme
ElexacaftorCytochrome P450 2C8enzyme
ElexacaftorCytochrome P450 2C9enzyme
ElexacaftorCytochrome P450 2C19enzyme
ElexacaftorCytochrome P450 2D6enzyme
ElexacaftorCystic fibrosis transmembrane conductance regulatortarget
CenobamateUDP-glucuronosyltransferase 2B7enzyme
CenobamateUDP-glucuronosyltransferase 2B4enzyme
CenobamateCytochrome P450 2E1enzyme
CenobamateCytochrome P450 2A6enzyme
CenobamateCytochrome P450 2B6enzyme
CenobamateCytochrome P450 2C19enzyme
CenobamateCytochrome P450 3A4enzyme
CenobamateCytochrome P450 3A5enzyme
CenobamateSerum albumincarrier
CenobamateCytochrome P450 2C8enzyme
SertralineSodium-dependent serotonin transportertarget
SertralineCytochrome P450 2B6enzyme
SertralineCytochrome P450 2C19enzyme
SertralineCytochrome P450 2C9enzyme
SertralineCytochrome P450 2D6enzyme
SertralineSodium-dependent dopamine transportertarget
SertralineCYP2B proteinenzyme
SertralineCytochrome P450 3A4enzyme
SertralineAmine oxidase [flavin-containing] Benzyme
SertralineAmine oxidase [flavin-containing] Aenzyme
SertralineP-glycoprotein 1transporter
SertralineSerum albumincarrier
SertralineSigma receptortarget
SertralineSodium-dependent noradrenaline transportertarget
SertralineEquilibrative nucleoside transporter 4target
SertralineCytochrome P450 2E1enzyme
LopinavirHuman immunodeficiency virus type 1 proteasetarget
LopinavirCytochrome P450 3A4enzyme
LopinavirCytochrome P450 2D6enzyme
LopinavirCytochrome P450 2C19enzyme
LopinavirP-glycoprotein 1transporter
LopinavirCytochrome P450 2B6enzyme
LopinavirCytochrome P450 2C9enzyme
LopinavirCytochrome P450 3A Subfamilyenzyme
LopinavirSolute carrier organic anion transporter family member 1B1transporter
LopinavirSolute carrier organic anion transporter family member 1B3transporter
LopinavirBile salt export pumptransporter
LopinavirCytochrome P450 1A2enzyme
LopinavirAlpha-1-acid glycoprotein 1carrier
LopinavirSerum albumincarrier
RitonavirHuman immunodeficiency virus type 1 proteasetarget
RitonavirCytochrome P450 2D6enzyme
RitonavirCytochrome P450 2C9enzyme
RitonavirCytochrome P450 2C19enzyme
RitonavirCytochrome P450 2B6enzyme
RitonavirCytochrome P450 2C8enzyme
RitonavirP-glycoprotein 1transporter
RitonavirMultidrug resistance-associated protein 1transporter
RitonavirCanalicular multispecific organic anion transporter 1transporter
RitonavirSolute carrier organic anion transporter family member 1A2transporter
RitonavirATP-binding cassette sub-family G member 2transporter
RitonavirSolute carrier organic anion transporter family member 1B1transporter
RitonavirCytochrome P450 1A2enzyme
RitonavirNuclear receptor subfamily 1 group I member 2target
RitonavirSerum albumincarrier
RitonavirCytochrome P450 3A4enzyme
RitonavirCytochrome P450 3A5enzyme
RitonavirCytochrome P450 3A7enzyme
RitonavirUDP-glucuronosyltransferases (UGTs)enzyme
RitonavirSolute carrier organic anion transporter family member 2B1transporter
RitonavirBile salt export pumptransporter
RitonavirAlpha-1-acid glycoprotein 1carrier
RitonavirSolute carrier organic anion transporter family member 1B3transporter
Methylene blueGuanylate cyclase soluble subunit alpha-2target
Methylene blueNitric oxide synthase, braintarget
Methylene blueUDP-glucuronosyltransferase 1-4enzyme
Methylene blueUDP-glucuronosyltransferase 1-9enzyme
Methylene blueCytochrome P450 1A2enzyme
Methylene blueCytochrome P450 2B6enzyme
Methylene blueCytochrome P450 2C8enzyme
Methylene blueCytochrome P450 2C9enzyme
Methylene blueCytochrome P450 2C19enzyme
Methylene blueCytochrome P450 3A4enzyme
Methylene blueCytochrome P450 3A5enzyme
Methylene blueSerum albumincarrier
Methylene blueP-glycoprotein 1transporter
Methylene blueSolute carrier family 22 member 2transporter
Methylene blueMultidrug and toxin extrusion protein 2transporter
Methylene blueMultidrug and toxin extrusion protein 1transporter
Methylene blueFlavin reductase (NADPH)enzyme
Methylene blueCytochrome P450 2D6enzyme