UGT1A1 Substrates with a Narrow Therapeutic Index
- Name
- UGT1A1 Substrates with a Narrow Therapeutic Index
- Accession Number
- DBCAT004530
- Description
Not Available
- Drugs
Drug Drug Description Levothyroxine A synthetic T4 hormone used to treat hypothyroidism that can be used along with surgery and radioiodine therapy to manage thyrotropin-dependent well-differentiated thyroid cancer. Mycophenolic acid An immunosuppressant used to prevent organ transplant rejections. Valproic acid An anticonvulsant used to control complex partial seizures and both simple and complex absence seizures. Enasidenib An isocitrate dehydrogenase-2 inhibitor used to treat relapsed or refractory acute myeloid leukemia with an isocitrate dehydrogenase-2 mutation. Belinostat A histone deacetylase (HDAC) inhibitor used for the treatment of patients with relapsed or refractory peripheral T-cell lymphoma (PTCL). Etoposide A podophyllotoxin derivative used to treat testicular and small cell lung tumors. Binimetinib A medication used to treat metastatic melanoma with specific mutations. Irinotecan An antineoplastic enzyme inhibitor used to treat metastatic carcinoma of the colon or rectum. Axitinib An oral VEGFR and kinase inhibitor used for the treatment of advanced renal cell carcinoma after failure of one prior systemic therapy. Phenytoin An anticonvulsant drug used in the prophylaxis and control of various types of seizures. - Drugs & Drug Targets