Folate Analog
- Name
- Folate Analog
- Accession Number
- DBCAT004536
- Description
Not Available
- Drugs
Drug Drug Description Leucovorin A folate analog used to treat the toxic effects of methotrexate and other folate antagonists, to treat megaloblastic anemia, and to provide palliative treatment of colorectal cancer. Levoleucovorin A folate analog used after high dose methotrexate for osteosarcoma, to reduce the toxic effects of folate analogs, and with 5-fluorouracil in palliative treatment of advanced metastatic colorectal cancer. Levomefolic acid A folate supplement used to prevent neural tube defects in pregnancy or folate deficiency. - Drugs & Drug Targets
Drug Target Type Leucovorin Solute carrier family 22 member 8 transporter Levoleucovorin Serine hydroxymethyltransferase target Levomefolic acid Proton-coupled folate transporter transporter Levomefolic acid Folate transporter 1 transporter Levomefolic acid Methionine synthase enzyme