Folate Analog

Name
Folate Analog
Accession Number
DBCAT004536
Description

Not Available

Drugs
DrugDrug Description
LeucovorinA folate analog used to treat the toxic effects of methotrexate and other folate antagonists, to treat megaloblastic anemia, and to provide palliative treatment of colorectal cancer.
LevoleucovorinA folate analog used after high dose methotrexate for osteosarcoma, to reduce the toxic effects of folate analogs, and with 5-fluorouracil in palliative treatment of advanced metastatic colorectal cancer.
Levomefolic acidA folate supplement used to prevent neural tube defects in pregnancy or folate deficiency.
Drugs & Drug Targets
DrugTargetType
LeucovorinSolute carrier family 22 member 8transporter
LevoleucovorinSerine hydroxymethyltransferasetarget
Levomefolic acidProton-coupled folate transportertransporter
Levomefolic acidFolate transporter 1transporter
Levomefolic acidMethionine synthaseenzyme