Polyvalent cation containing laxatives, antacids, oral supplements

This category is comprised of polyvalent cation-containing drugs that may interfere with the absorption of other drugs.
DrugDrug NameDrug Description
DB11093Calcium CitrateAn ingredient found in a variety of supplements and vitamins.
DB06724Calcium carbonateAn ionic compound used as a calcium supplement or antacid used for the symptomatic relief of heartburn, acid indigestion, and sour stomach.
DB14485Zinc ascorbateA medication used to prevent the absorption of copper in Wilson's disease and also as part of natural health products.
DB14494Zinc carbonateNot Annotated
DB11135SeleniumAn ingredient found in a variety of supplements and vitamins.
DB14519Aluminum cationNot Annotated
DB01378Magnesium cationMagnesium hydroxide is used primarily in "Milk of Magnesia", a white aqueous, mildly alkaline suspension of magnesium hydroxide formulated at about 8%w/v. Milk of magnesia is primarily used to alleviate...
DB14532Zinc cationNot Annotated
DB14577Calcium cationNot Annotated
DB13949Ferric cationFor the control of serum phosphorus levels in patients with chronic kidney disease on dialysis, as ferric citrate.
DB14490Ferrous ascorbateA medication used to treat iron-deficiency anemia.
DB14488Ferrous gluconateA medication used to treat iron-deficiency anemia.
DB13257Ferrous sulfate anhydrousAn iron supplement used to prevent iron deficiency anemia.
DrugDrug NameTargetType
DB11093Calcium CitrateTransient receptor potential cation channel subfamily V member 6transporter
DB11093Calcium CitrateCalbindincarrier
DB11093Calcium CitrateProtein S100-Gcarrier
DB11093Calcium CitrateSodium/calcium exchanger 1transporter
DB11093Calcium CitrateTransient receptor potential cation channel subfamily V member 5transporter
DB11093Calcium CitrateExtracellular calcium-sensing receptortarget
DB11093Calcium CitrateCalreticulintarget
DB11093Calcium CitrateCalcium and integrin-binding protein 1target
DB11093Calcium CitrateProgrammed cell death protein 6target
DB11093Calcium CitrateSorcintarget
DB11093Calcium CitrateCalcineurin B homologous protein 1target
DB11093Calcium CitrateSPARCtarget
DB11093Calcium CitrateCalnexintarget
DB11093Calcium CitrateFibrillin-2target
DB11093Calcium CitrateProtein S100-Btarget
DB11093Calcium CitrateCalsequestrin-2target
DB11093Calcium CitrateRegucalcintarget
DB11093Calcium CitratePeflintarget
DB11093Calcium CitrateProtein S100-A6target
DB11093Calcium CitrateTranslationally-controlled tumor proteintarget
DB11093Calcium CitrateCalcium and integrin-binding family member 2target
DB11093Calcium CitrateProtein S100-A13target
DB11093Calcium CitrateCalsequestrin-1target
DB11093Calcium CitrateNucleobindin-1target
DB11093Calcium CitrateNucleobindin-2target
DB11093Calcium CitrateCalmodulintarget
DB11093Calcium CitrateFibrillin-3target
DB11093Calcium CitrateGrancalcintarget
DB11093Calcium CitrateCalcium-dependent secretion activator 1target
DB11093Calcium CitrateSerum albumincarrier
DB11093Calcium CitrateCalmodulin-2target
DB11093Calcium CitrateCalmodulin-3target
DB11093Calcium CitrateProtein S100-A16target
DB11093Calcium CitrateCalretinintarget
DB11093Calcium CitrateCalcyphosintarget
DB11093Calcium CitrateCalcium-dependent secretion activator 2target
DB11093Calcium CitrateCalreticulin-3target
DB11093Calcium CitrateRyanodine receptor 1transporter
DB11093Calcium CitrateRyanodine receptor 2transporter
DB11093Calcium CitratePolycystic kidney disease 2-like 1 proteintransporter
DB11093Calcium CitrateNeurexin-1target
DB11093Calcium CitrateNeuronal calcium sensor 1target
DB11093Calcium CitrateRyanodine receptor 3transporter
DB11093Calcium CitratePolycystic kidney disease protein 1-like 3transporter
DB11093Calcium CitrateCation channel sperm-associated protein 1transporter
DB11093Calcium CitrateVoltage-dependent L-type calcium channeltransporter
DB11093Calcium CitrateVoltage-dependent P/Q-type calcium channeltransporter
DB11093Calcium CitrateVoltage-dependent T-type calcium channeltransporter
DB11093Calcium CitrateVoltage-dependent R-type calcium channeltransporter
DB11135SeleniumSelenocysteine lyaseenzyme
DB11135SeleniumGlutathione reductase, mitochondrialenzyme
DB11135SeleniumThioredoxin reductase 1, cytoplasmicenzyme
DB01378Magnesium cationSodium/potassium-transporting ATPase subunit alpha-1target
DB13949Ferric cationSerotransferrincarrier
DB13949Ferric cationIron(3+)-hydroxamate-binding protein FhuDtarget
DB13949Ferric cationIntegrin beta-3carrier
DB13949Ferric cationCalreticulincarrier
DB13949Ferric cationTransferrin receptor protein 1target
DB14490Ferrous ascorbateTransferrin receptor protein 1target
DB14490Ferrous ascorbateEgl nine homolog 1target
DB14490Ferrous ascorbateHistone deacetylase 8target
DB14490Ferrous ascorbateAlpha-hemoglobin-stabilizing proteintarget
DB14490Ferrous ascorbateHemoglobin subunit alphatarget
DB14490Ferrous ascorbateFrataxin, mitochondrialtarget
DB14490Ferrous ascorbateFerritin heavy chaintarget
DB14490Ferrous ascorbateFlap endonuclease 1target
DB14490Ferrous ascorbateEndonuclease 8-like 1target
DB14490Ferrous ascorbateEndonuclease 8-like 2target
DB14490Ferrous ascorbateDNA polymerase betatarget
DB14490Ferrous ascorbateCeruloplasmintarget
DB14490Ferrous ascorbateSerotransferrintarget
DB14488Ferrous gluconateTransferrin receptor protein 1target
DB14488Ferrous gluconateEgl nine homolog 1target
DB14488Ferrous gluconateHistone deacetylase 8target
DB14488Ferrous gluconateAlpha-hemoglobin-stabilizing proteintarget
DB14488Ferrous gluconateHemoglobin subunit alphatarget
DB14488Ferrous gluconateFrataxin, mitochondrialtarget
DB14488Ferrous gluconateFerritin heavy chaintarget
DB14488Ferrous gluconateFlap endonuclease 1target
DB14488Ferrous gluconateEndonuclease 8-like 1target
DB14488Ferrous gluconateEndonuclease 8-like 2target
DB14488Ferrous gluconateDNA polymerase betatarget
DB14488Ferrous gluconateCeruloplasmintarget
DB14488Ferrous gluconateSerotransferrintarget
DB13257Ferrous sulfate anhydrousSerotransferrintransporter
DB13257Ferrous sulfate anhydrousFerritin light chaintransporter
DB13257Ferrous sulfate anhydrousFerritin heavy chaintransporter
DB13257Ferrous sulfate anhydrousDivalent metal ion transporter 1transporter
DB13257Ferrous sulfate anhydrousIron binding protein FbpAtransporter
DB13257Ferrous sulfate anhydrousNADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrialenzyme
DB13257Ferrous sulfate anhydrousSuccinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrialenzyme
DB13257Ferrous sulfate anhydrousXanthine dehydrogenase/oxidaseenzyme
DB13257Ferrous sulfate anhydrousAconitate hydratase, mitochondrialenzyme
DB13257Ferrous sulfate anhydrousCytochrome P450 4A11enzyme
DB13257Ferrous sulfate anhydrousSulfite oxidase, mitochondrialenzyme
DB13257Ferrous sulfate anhydrousMyeloperoxidaseenzyme
DB13257Ferrous sulfate anhydrousCatalaseenzyme
DB13257Ferrous sulfate anhydrousNitric oxide synthase, inducibleenzyme
DB13257Ferrous sulfate anhydrousProstaglandin G/H synthase 1enzyme
DB13257Ferrous sulfate anhydrousProstaglandin G/H synthase 2enzyme
DB13257Ferrous sulfate anhydrousTryptophan 5-hydroxylase 1enzyme
DB13257Ferrous sulfate anhydrousProlyl 4-hydroxylase subunit alpha-1enzyme
DB13257Ferrous sulfate anhydrousPterin-4-alpha-carbinolamine dehydrataseenzyme
DB13257Ferrous sulfate anhydrousCeruloplasminenzyme
DB13257Ferrous sulfate anhydrousFree radicalstarget