Non COX-2 selective NSAIDS

Name
Non COX-2 selective NSAIDS
Accession Number
DBCAT004608
Description

This category is only comprised of NSAIDS that non selectively inhibit COX and show no selectivity for COX2. They may inhibit both COX1 and COX2, but not COX2 alone.

Drugs
DrugDrug Description
AcemetacinAcemetacin is not FDA, Canada or EMA approved, but in the countries where it is marketed it is indicated for the symptomatic treatment of pain and swelling in acute inflammation...
Acetylsalicylic acidA salicylate used to treat pain, fever, inflammation, migraines, and reducing the risk of major adverse cardiovascular events.
AlclofenacAlclofenac is indicated in rheumatology, in particular for the treatment of rheumatoid arthritis, ankylosing spondylitis and, as an analgesic, in painful arthritic pathologies.
AlminoprofenAlminoprofen is a non-steroidal anti-inflammatory drug (NSAID) whose physiochemical characteristics make it a member of the phenylpropionic acid class of chemical substances.
AminophenazoneFormerly widely used as an antipyretic and analgesic in rheumatism, neuritis, and common colds. Currently used to measure total body water.
AntipyrineAn antipyretic agent used for the symptomatic treatment of acute otitis media, most commonly in combination with benzocaine.
AntrafenineAntrafenine is used as an anti-inflammatory and analgesic agent for the relief of mild to moderate pain.
BalsalazideAn aminosalicylate used to treat ulcerative colitis.
BendazacPrior to the withdrawal of bendazac from various international regions of use due to concerns for hepatotoxicity [A39891, A39892, A39893, L4778] the chemical had demonstrated potential usefulness predominantly as the...
BenorilateNot Annotated
BenzydamineA locally-acting NSAID indicated for the symptomatic relief of pain in acute sore throat and for the symptomatic relief of oropharyngeal mucositis caused by radiation therapy.
Betulinic AcidBetulinic Acid has been used in trials studying the treatment of Dysplastic Nevus Syndrome.
BufexamacAn NSAID used to treat skin conditions like atopic eczema and inflammatory dermatoses.
BumadizoneBumadizone has been approved for use in Germany and Austria, it is a drug with anti-inflammatory, antipyretic, and analgesic properties, and was marketed for the treatment of both rheumatoid arthritis...
Carbaspirin calciumNot Annotated
Choline magnesium trisalicylateCholine magnesium trisalicylate is used to reduce pain and inflammation caused by conditions such as arthritis. This medication is also used to treat fever in adults.
ClonixinIndicated for use in the management of chronic arthritic conditions and certain soft tissue disorders associated with pain and inflammation.
DexibuprofenFor more information, refer to ibuprofen.
DexketoprofenFor short-term treatment of mild to moderate pain, including dysmenorrhoea, musculoskeletal pain and toothache .
DiclofenacAn NSAID used to treat the signs and symptoms of osteoarthritis and rheumatoid arthritis.
DifenpiramideNot Annotated
DiflunisalAn NSAID used to treat mild to moderate pain, inflammation, osteoarthritis, and rheumatoid arthritis.
DroxicamDroxicam is an NSAID previously used for the treatment of inflammation and rheumatoid arthritis .
EpirizoleEpirizole is an oral nonsteroidal anti-inflammatory drug (NSAID) used for muscle and joint pain.
EthenzamideNot Annotated
EtofenamateEtofenamate is used to treat muscle and joint paint. It is a non-steroidal anti-inflammatory drug (NSAID).
FelbinacNot Available
FenbufenFenbufen is a non-steroidal anti-inflammatory drug used primarily to treat inflammation in osteoarthritis, ankylosing spondylitis, and tendinitis. It can also be used to relieve backaches, sprains, and fractures. Fenbufen is...
FenoprofenAn anti-inflammatory analgesic used to treat mild to moderate pain in addition to the signs and symptoms of rheumatoid arthritis and osteoarthritis.
FentiazacNot Annotated
FeprazoneNot Annotated
FloctafenineAn anti-inflammatory analgesic used to manage mild to moderate acute pain.
FlunixinFlunixin is a non-steroidal anti-inflammatory drug for use in pigs, cattle and horses. It exerts analgesic and antipyretic effects. This drug is often prepared for use in meglumine salt form....
FlunoxaprofenNot Annotated
FlurbiprofenAn NSAID used to treat the signs and symptoms of osteoarthritis and rheumatoid arthritis.
GuacetisalNot Annotated
IbuprofenAn NSAID and non-selective COX inhibitor used to treat mild-moderate pain, fever, and inflammation.
IbuproxamIbuproxam is a non steroidal anti-inflammatory drug (NSAID).
IcosapentA polyunsaturated fatty acid, usually found in fish oils, that is used in many supplements.
Imidazole salicylateNot Annotated
IndobufenIndobufen has been used in trials studying the supportive care and prevention of Atrial Fibrillation.
IndomethacinA nonsteroidal anti-inflammatory (NSAID) used for symptomatic management of chronic musculoskeletal pain conditions and to induce closure of a hemodynamically significant patent ductus arteriosus in premature infants.
IndoprofenA drug that has analgesic and anti-inflammatory properties. Following reports of adverse reactions including reports of carcinogenicity in animal studies it was withdrawn from the market worldwide.
IsoxicamIsoxicam is a non-steroidal anti-inflammatory drug that is not marketed in the United States.
KebuzoneKebuzone (also known as ketophenylbutazone ) is a non-steroidal anti-inflammatory drug.
KetoprofenAn NSAID used to treat rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, dysmenorrhea, mild to moderate muscle pain, postoperative pain, and postpartum pain.
KetorolacAn NSAID used to treat moderate to severe pain, rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, menstrual disorders, and headaches.
LonazolacNot Annotated
LornoxicamFor the treatment of acute mild to moderate pain, as well as pain and inflammation of the joints caused by certain types of rheumatic diseases.
LoxoprofenLoxoprofen is non-steroidal anti-inflammatory medication (NSAID) indicated for pain and inflammation related to musculoskeletal and joint disorders. In addition to its effects on pain, it is an antipyretic and anti-inflammatory...
Magnesium salicylateAn NSAID analgesic used in the symptomatic relief of mild to moderate muscular pain.
Meclofenamic acidAn NSAID used to treat mild to moderate pain, primary dysmenorrhea, heavy menstrual blood loss, rheumatoid arthritis, and osteoarthritis.
MesalazineAn aminosalicylate drug used to treat mild to moderate active ulcerative colitis and also to maintain remission once achieved.
MetamizoleUsed in the past as a powerful painkiller and fever reducer.
NaproxenAn NSAID used to treat rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, polyarticular juvenile idiopathic arthritis, tendinitis, bursitis, acute gout, primary dysmenorrhea, and mild to moderate pain.
NifenazoneNot Annotated
NitroaspirinNitroaspirin has been investigated for the treatment of Intermittent Claudication.
OlsalazineAn anti-inflammatory agent used in the treatment of inflammatory bowel disease and ulcerative colitis.
OxaprozinAn NSAID used to treat osteoarthritis, rheumatoid arthritis, and juvenile rheumatoid arthritis.
OxyphenbutazoneA nonsteroidal anti-inflammatory drug (NSAID) no longer commonly used for the symptomatic relief of musculoskeletal pain.
PhenylbutazoneAn NSAID used to treat backache and ankylosing spondylitis.
PiroxicamAn NSAID used to treat the symptoms of osteoarthritis and rheumatoid arthritis.
PirprofenNot Annotated
PranoprofenNot Annotated
ProglumetacinNot Annotated
PropacetamolPropacetamol is a paracetamol prodrug of intravenous administration used to control fever and pain of perioperative period in multimodal analgesia therapy.
PropyphenazoneNot Annotated
SalicylamideSalicylamide is the common name for the substance o-hydroxybenzamide, or amide of salicyl. Salicylamide is a non-prescription drug with analgesic and antipyretic properties. It has similar medicinal uses to aspirin....
Salicylic acidAn acid used to treat acne, psoriasis, calluses, corns, keratosis pilaris, and warts.
SalsalateA nonsteroidal anti-inflammatory agent used in the symptomatic relief of rheumatoid arthritis, osteoarthritis and related rheumatic disorders.
SulfasalazineAn anti-inflammatory drug used to treat Crohn's disease and rheumatoid arthritis.
SulindacAn NSAID used to treat osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, acute subacromial bursitis or supraspinatus tendinitis, and acute gouty arthritis.
SuprofenAn NSAID used to prevent pupil constriction in ocular surgery.
ZaltoprofenA non-steroidal anti-inflammatory drug approved for use in Japan in 1993.
SuxibuzoneNot Annotated
TaxifolinNot Available
TenidapNot Annotated
TenoxicamAn anti inflammatory analgesic used to treat mild to moderate pain as well as the signs and symptoms of rheumatoid arthritis and osteoarthritis.
TepoxalinTepoxalin is a nonsteroidal anti-inflammatory drug approved for veterinary use in the United States and many other countries. It is primarily used to reduce inflammation and relief of pain caused...
Tiaprofenic acidA nonsteroidal anti-inflammatory (NSAID) used to manage inflammation and analgesia associated with rheumatoid arthritis and osteoarthritis.
Tolfenamic acidIn the information for tolfenamic acid, it is stated that this drug, being an NSAID, is effective in treating the pain associated with the acute attack of migraines in adults.
TolmetinAn NSAID used to treat acute flares of various painful conditions and used for the long term management of osteoarthritis, rheumatoid arthritis, and juvenile arthritis.
Trolamine salicylateA medication used to relieve minor aches and pains of the muscles and joints.
ZomepiracZomepirac was indicated for the management of mild to severe pain.
Drugs & Drug Targets
DrugTargetType
AcemetacinProstaglandin G/H synthase 1target
AcemetacinProstaglandin G/H synthase 2target
AcemetacinUDP-glucuronosyltransferase 2B7enzyme
AcemetacinMultidrug resistance-associated protein 1transporter
Acetylsalicylic acidProstaglandin G/H synthase 1target
Acetylsalicylic acidProstaglandin G/H synthase 2target
Acetylsalicylic acidAldo-keto reductase family 1 member C1target
Acetylsalicylic acidSolute carrier family 22 member 6transporter
Acetylsalicylic acidP-glycoprotein 1transporter
Acetylsalicylic acidCytochrome P450 2C19enzyme
Acetylsalicylic acidCytochrome P450 2C9enzyme
Acetylsalicylic acid5'-AMP-activated protein kinasetarget
Acetylsalicylic acidEndothelin-1 receptortarget
Acetylsalicylic acidCellular tumor antigen p53target
Acetylsalicylic acid78 kDa glucose-regulated proteintarget
Acetylsalicylic acidRibosomal protein S6 kinase alpha-3target
Acetylsalicylic acidNF-kappa-B inhibitor alphatarget
Acetylsalicylic acidTumor necrosis factor-inducible gene 6 proteintarget
Acetylsalicylic acidCaspase-1target
Acetylsalicylic acidCaspase-3target
Acetylsalicylic acidInhibitor of nuclear factor kappa-B kinase subunit betatarget
Acetylsalicylic acidExtracellular signal-regulated kinase (ERK)target
Acetylsalicylic acidG1/S-specific cyclin-D1target
Acetylsalicylic acidMyc proto-oncogene proteintarget
Acetylsalicylic acidProliferating cell nuclear antigentarget
Acetylsalicylic acidCyclin Atarget
Acetylsalicylic acidUDP-glucuronosyltransferase 1-6enzyme
Acetylsalicylic acidArylamine N-acetyltransferase 2enzyme
Acetylsalicylic acidSolute carrier family 22 member 8transporter
AlclofenacProstaglandin G/H synthase 2target
AminophenazoneCytochrome P450 2C19enzyme
AminophenazoneCytochrome P450 1A2enzyme
AminophenazoneCytochrome P450 2C8enzyme
AminophenazoneSolute carrier family 22 member 6transporter
AminophenazoneCytochrome P450 2C9enzyme
AminophenazoneCytochrome P450 2D6enzyme
AminophenazoneCytochrome P450 3A4enzyme
AminophenazoneCytochrome P450 2C18enzyme
AminophenazoneSteroid 17-alpha-hydroxylase/17,20 lyaseenzyme
AntipyrineCytochrome P450 2C8enzyme
AntipyrineCytochrome P450 2C9enzyme
AntipyrineCytochrome P450 1A2enzyme
AntipyrineCytochrome P450 2C19enzyme
AntipyrineCytochrome P450 3A4enzyme
AntipyrineSolute carrier family 22 member 6transporter
AntipyrineCytochrome P450 2A6enzyme
AntipyrineCytochrome P450 2B6enzyme
AntipyrineCytochrome P450 2C18enzyme
AntipyrineCytochrome P450 2D6enzyme
AntipyrineCytochrome P450 2E1enzyme
AntipyrineProstaglandin G/H synthase 2target
AntipyrineProstaglandin G/H synthase 1target
AntrafenineProstaglandin G/H synthase 1target
AntrafenineProstaglandin G/H synthase 2target
BalsalazideProstaglandin G/H synthase 1target
BalsalazideProstaglandin G/H synthase 2target
BalsalazideArachidonate 5-lipoxygenasetarget
BalsalazidePeroxisome proliferator-activated receptor gammatarget
BalsalazideNADPH azoreductaseenzyme
BendazacFree radicalstarget
BendazacProstaglandin G/H synthase 1target
BendazacProstaglandin G/H synthase 2target
BufexamacProstaglandin G/H synthase 1target
BufexamacProstaglandin G/H synthase 2target
BufexamacHistone deacetylase 6target
BufexamacHistone deacetylase 10target
Choline magnesium trisalicylateProstaglandin G/H synthase 1target
Choline magnesium trisalicylateProstaglandin G/H synthase 2target
DexibuprofenProstaglandin G/H synthase 1target
DexibuprofenProstaglandin G/H synthase 2target
DexibuprofenApoptosis regulator Bcl-2target
DexibuprofenThrombomodulintarget
DexibuprofenTissue-type plasminogen activatortarget
DexibuprofenFatty acid-binding protein, intestinaltarget
DexibuprofenPeroxisome proliferator-activated receptor gammatarget
DexibuprofenCystic fibrosis transmembrane conductance regulatortarget
DexibuprofenCytochrome P450 2C9enzyme
DexibuprofenSerum albumincarrier
DexibuprofenMultidrug resistance-associated protein 4transporter
DexibuprofenMultidrug resistance-associated protein 1transporter
DexibuprofenSolute carrier organic anion transporter family member 1A2transporter
DexibuprofenSolute carrier family 22 member 6transporter
DexibuprofenSolute carrier family 22 member 8transporter
DexibuprofenSolute carrier family 22 member 11transporter
DexibuprofenSolute carrier organic anion transporter family member 2B1transporter
DexibuprofenP-glycoprotein 1transporter
DexibuprofenUDP-glucuronosyltransferase 1-1enzyme
DexibuprofenUDP-glucuronosyltransferase 1-3enzyme
DexibuprofenUDP-glucuronosyltransferase 1-9enzyme
DexibuprofenUDP-glucuronosyltransferase 2B4enzyme
DexibuprofenUDP-glucuronosyltransferase 2B7enzyme
DexibuprofenCytochrome P450 2C8enzyme
DexibuprofenCytochrome P450 2C19enzyme
DexibuprofenSolute carrier family 15 member 1target
DexibuprofenPeroxisome proliferator-activated receptor alphatarget
DexibuprofenPlatelet glycoprotein Ib alpha chaintarget
DexibuprofenProtein S100-A7target
DexibuprofenAlpha-methylacyl-CoA racemaseenzyme
DexketoprofenProstaglandin G/H synthase 1target
DexketoprofenProstaglandin G/H synthase 2target
DexketoprofenProstaglandin G/H synthase 1enzyme
DexketoprofenProstaglandin G/H synthase 2enzyme
DiclofenacProstaglandin G/H synthase 1target
DiclofenacProstaglandin G/H synthase 2target
DiclofenacTransthyretincarrier
DiclofenacCytochrome P450 2C9enzyme
DiclofenacCytochrome P450 2C19enzyme
DiclofenacCytochrome P450 1A2enzyme
DiclofenacCytochrome P450 2C8enzyme
DiclofenacSerum albumincarrier
DiclofenacMultidrug resistance-associated protein 4transporter
DiclofenacMultidrug resistance-associated protein 1transporter
DiclofenacSolute carrier family 22 member 6transporter
DiclofenacSolute carrier family 22 member 8transporter
DiclofenacSolute carrier organic anion transporter family member 1C1transporter
DiclofenacSolute carrier family 22 member 11transporter
DiclofenacUDP-glucuronosyltransferase 2B7enzyme
DiclofenacCytochrome P450 3A4enzyme
DiclofenacCytochrome P450 2B6enzyme
DiclofenacCytochrome P450 2C18enzyme
DiclofenacCytochrome P450 2E1enzyme
DiclofenacSolute carrier organic anion transporter family member 1B1transporter
DiclofenacBile salt export pumptransporter
DiclofenacUDP-glucuronosyltransferase 1-3enzyme
DiclofenacUDP-glucuronosyltransferase 1-9enzyme
DiclofenacUDP-glucuronosyltransferase 2B4enzyme
DiclofenacArachidonate 5-lipoxygenaseenzyme
DiclofenacSodium channel protein type 4 subunit alphatransporter
DiclofenacAcid-sensing ion channel 1transporter
DiclofenacPotassium voltage-gated channel subfamily KQT member 2transporter
DiclofenacPotassium voltage-gated channel subfamily KQT member 3transporter
DiclofenacPhospholipase A2, membrane associatedenzyme
DiclofenacP-glycoprotein 1transporter
DiflunisalProstaglandin G/H synthase 1target
DiflunisalProstaglandin G/H synthase 2target
DiflunisalTransthyretincarrier
DiflunisalSerum albumincarrier
DiflunisalSolute carrier family 22 member 6transporter
DiflunisalUDP-glucuronosyltransferase 1-8enzyme
DiflunisalUDP-glucuronosyltransferase 1-9enzyme
DroxicamProstaglandin G/H synthase 1target
DroxicamProstaglandin G/H synthase 2target
EtofenamateThyroxine-binding globulincarrier
FelbinacCathepsin L1target
FenoprofenProstaglandin G/H synthase 1target
FenoprofenProstaglandin G/H synthase 2target
FenoprofenSerum albumincarrier
FenoprofenPeroxisome proliferator-activated receptor alphatarget
FenoprofenPeroxisome proliferator-activated receptor gammatarget
FlurbiprofenProstaglandin G/H synthase 2target
FlurbiprofenProstaglandin G/H synthase 1target
FlurbiprofenCytochrome P450 2C9enzyme
FlurbiprofenSerum albumincarrier
FlurbiprofenMultidrug resistance-associated protein 4transporter
FlurbiprofenSolute carrier family 22 member 6transporter
FlurbiprofenUDP-glucuronosyltransferase 2B7enzyme
FlurbiprofenUDP-glucuronosyltransferase 1-1enzyme
FlurbiprofenUDP-glucuronosyltransferase 1-3enzyme
FlurbiprofenUDP-glucuronosyltransferase 1-9enzyme
FlurbiprofenUDP-glucuronosyltransferase 2B4enzyme
IbuprofenProstaglandin G/H synthase 1target
IbuprofenProstaglandin G/H synthase 2target
IbuprofenCytochrome P450 2C9enzyme
IbuprofenSerum albumincarrier
IbuprofenMultidrug resistance-associated protein 4transporter
IbuprofenMultidrug resistance-associated protein 1transporter
IbuprofenSolute carrier organic anion transporter family member 1A2transporter
IbuprofenSolute carrier family 22 member 6transporter
IbuprofenSolute carrier family 22 member 8transporter
IbuprofenSolute carrier family 22 member 11transporter
IbuprofenSolute carrier organic anion transporter family member 2B1transporter
IbuprofenP-glycoprotein 1transporter
IbuprofenUDP-glucuronosyltransferase 1-3enzyme
IbuprofenUDP-glucuronosyltransferase 1-9enzyme
IbuprofenUDP-glucuronosyltransferase 2B4enzyme
IbuprofenUDP-glucuronosyltransferase 2B7enzyme
IbuprofenCytochrome P450 2C8enzyme
IbuprofenCytochrome P450 2C19enzyme
IbuprofenApoptosis regulator Bcl-2target
IbuprofenThrombomodulintarget
IbuprofenFatty acid-binding protein, intestinaltarget
IbuprofenPeroxisome proliferator-activated receptor gammatarget
IbuprofenCystic fibrosis transmembrane conductance regulatortarget
IbuprofenPeroxisome proliferator-activated receptor alphatarget
IbuprofenPlatelet glycoprotein Ib alpha chaintarget
IbuprofenProtein S100-A7target
IbuprofenAlpha-methylacyl-CoA racemaseenzyme
IbuprofenCytochrome P450 3A4enzyme
IcosapentProstaglandin G/H synthase 2target
IcosapentProstaglandin G/H synthase 1target
IcosapentFree fatty acid receptor 1target
IcosapentFatty acid-binding protein, braincarrier
IcosapentFatty acid desaturase 1target
IcosapentLong-chain-fatty-acid--CoA ligase 4target
IcosapentLong-chain-fatty-acid--CoA ligase 3target
IcosapentSodium/calcium exchanger 1target
IcosapentPeroxisome proliferator-activated receptor gammatarget
IcosapentPeroxisome proliferator-activated receptor deltatarget
IcosapentTransient receptor potential cation channel subfamily V member 1target
IcosapentPeroxisome proliferator-activated receptor alphatarget
IcosapentSerum albumincarrier
IndomethacinProstaglandin G/H synthase 1target
IndomethacinProstaglandin G/H synthase 2target
IndomethacinCytochrome P450 2C19enzyme
IndomethacinUDP-glucuronosyltransferase 1-9enzyme
IndomethacinPhospholipase A2, membrane associatedtarget
IndomethacinProstaglandin reductase 2target
IndomethacinLactoylglutathione lyasetarget
IndomethacinProstaglandin D2 receptor 2target
IndomethacinPeroxisome proliferator-activated receptor gammatarget
IndomethacinSerum albumincarrier
IndomethacinCanalicular multispecific organic anion transporter 2transporter
IndomethacinMultidrug resistance-associated protein 4transporter
IndomethacinMultidrug resistance-associated protein 6transporter
IndomethacinP-glycoprotein 1transporter
IndomethacinMultidrug resistance-associated protein 1transporter
IndomethacinSolute carrier organic anion transporter family member 1A2transporter
IndomethacinSolute carrier family 22 member 6transporter
IndomethacinSolute carrier family 22 member 8transporter
IndomethacinCanalicular multispecific organic anion transporter 1transporter
IndomethacinATP-binding cassette sub-family C member 11transporter
IndomethacinSolute carrier family 22 member 11transporter
IndomethacinSodium/bile acid cotransportertransporter
IndomethacinSolute carrier family 22 member 7transporter
IndomethacinCytochrome P450 2C9enzyme
IndomethacinUDP-glucuronosyltransferase 1-1enzyme
IndomethacinLiver carboxylesterase 1enzyme
IndomethacinUDP-glucuronosyltransferase 2B7enzyme
IndomethacinPeroxisome proliferator-activated receptor alphatarget
IndomethacinAldo-keto reductase family 1 member C3target
IndomethacinSolute carrier organic anion transporter family member 1B1transporter
IndomethacinBile salt export pumptransporter
KetoprofenProstaglandin G/H synthase 1target
KetoprofenProstaglandin G/H synthase 2target
KetoprofenC-X-C chemokine receptor type 1target
KetoprofenSerum albumincarrier
KetoprofenMultidrug resistance-associated protein 4transporter
KetoprofenSolute carrier organic anion transporter family member 1A2transporter
KetoprofenSolute carrier family 22 member 6transporter
KetoprofenSolute carrier family 22 member 8transporter
KetoprofenSolute carrier family 22 member 11transporter
KetoprofenSolute carrier family 22 member 7transporter
KetoprofenCytochrome P450 2C9enzyme
KetoprofenCytochrome P450 2C8enzyme
KetoprofenUDP-glucuronosyltransferase 1-1enzyme
KetorolacProstaglandin G/H synthase 1target
KetorolacProstaglandin G/H synthase 2target
KetorolacUDP-glucuronosyltransferase 2B7enzyme
KetorolacCytochrome P450 2C8enzyme
KetorolacCytochrome P450 2C9enzyme
LornoxicamCytochrome P450 2C9enzyme
LornoxicamProstaglandin G/H synthase 1target
LornoxicamProstaglandin G/H synthase 2target
LoxoprofenProstaglandin G/H synthase 2target
LoxoprofenProstaglandin G/H synthase 1target
LoxoprofenCarbonyl reductase [NADPH] 1enzyme
LoxoprofenCytochrome P450 3A Subfamilyenzyme
LoxoprofenUDP-glucuronosyltransferase 2B7enzyme
Magnesium salicylateSerum albumincarrier
Magnesium salicylateProstaglandin G/H synthase 1target
Magnesium salicylateProstaglandin G/H synthase 2target
Meclofenamic acidProstaglandin G/H synthase 1target
Meclofenamic acidProstaglandin G/H synthase 2target
Meclofenamic acidArachidonate 5-lipoxygenasetarget
Meclofenamic acidSolute carrier family 22 member 6transporter
Meclofenamic acidSolute carrier organic anion transporter family member 1C1transporter
Meclofenamic acidPotassium voltage-gated channel subfamily KQT member 2target
Meclofenamic acidPotassium voltage-gated channel subfamily KQT member 3target
Meclofenamic acidThyroxine-binding globulincarrier
MesalazineProstaglandin G/H synthase 1target
MesalazineProstaglandin G/H synthase 2target
MesalazinePeroxisome proliferator-activated receptor gammatarget
MesalazineInhibitor of nuclear factor kappa-B kinase subunit alphatarget
MesalazineInhibitor of nuclear factor kappa-B kinase subunit betatarget
MesalazineArachidonate 5-lipoxygenasetarget
MesalazineMyeloperoxidasetarget
MesalazineArylamine N-acetyltransferasetarget
MesalazineArylamine N-acetyltransferase 1enzyme
MetamizoleProstaglandin G/H synthase 1target
MetamizoleCytochrome P450 2B6enzyme
MetamizoleCytochrome P450 3A4enzyme
NaproxenProstaglandin G/H synthase 1target
NaproxenProstaglandin G/H synthase 2target
NaproxenSerum albumincarrier
NaproxenCytochrome P450 2C9enzyme
NaproxenCytochrome P450 1A2enzyme
NaproxenSolute carrier organic anion transporter family member 1A2transporter
NaproxenSolute carrier family 22 member 6transporter
NaproxenCytochrome P450 2C8enzyme
NaproxenUDP-glucuronosyltransferase 2B7enzyme
NaproxenPeptostreptococcal albumin-binding proteintarget
NaproxenBile salt export pumptransporter
NaproxenP-glycoprotein 1transporter
NaproxenUDP-glucuronosyltransferase 1-3enzyme
NaproxenUDP-glucuronosyltransferase 1-6enzyme
NaproxenUDP-glucuronosyltransferase 1-7enzyme
NaproxenUDP-glucuronosyltransferase 1-8enzyme
NaproxenUDP-glucuronosyltransferase 1-9enzyme
NaproxenUDP-glucuronosyltransferase 1-10enzyme
NaproxenSolute carrier family 22 member 8transporter
NitroaspirinProstaglandin G/H synthase 1target
OlsalazineInterferon gammatarget
OlsalazineThiopurine S-methyltransferasetarget
OxaprozinProstaglandin G/H synthase 2target
OxaprozinProstaglandin G/H synthase 1target
OxyphenbutazoneGroup IIE secretory phospholipase A2target
OxyphenbutazoneSerum albumincarrier
OxyphenbutazoneSolute carrier family 22 member 6transporter
PhenylbutazoneProstaglandin G/H synthase 2target
PhenylbutazoneProstacyclin synthasetarget
PhenylbutazoneCytochrome P450 2C9enzyme
PhenylbutazoneSolute carrier family 22 member 6transporter
PhenylbutazoneSolute carrier family 22 member 8transporter
PhenylbutazoneSolute carrier family 22 member 11transporter
PhenylbutazoneProstaglandin G/H synthase 1target
PhenylbutazoneCytochrome P450 3A4enzyme
PiroxicamProstaglandin G/H synthase 1target
PiroxicamProstaglandin G/H synthase 2target
PiroxicamSerum albumincarrier
PiroxicamCytochrome P450 2C9enzyme
PiroxicamSolute carrier family 22 member 6transporter
PiroxicamSolute carrier family 22 member 8transporter
PiroxicamSolute carrier family 22 member 11transporter
PiroxicamCytochrome P450 2C8enzyme
PiroxicamSolute carrier organic anion transporter family member 2B1transporter
PropacetamolCholinesteraseenzyme
PropacetamolProstaglandin G/H synthase 1target
PropacetamolProstaglandin G/H synthase 2target
PropacetamolTransient receptor potential cation channel subfamily V member 1target
PropacetamolCannabinoid receptor 1target
PropacetamolCytochrome P450 2E1enzyme
PropacetamolCytochrome P450 1A2enzyme
PropacetamolCytochrome P450 2D6enzyme
PropacetamolUDP-glucuronosyltransferase 1-1enzyme
PropacetamolUDP-glucuronosyltransferase 1-6enzyme
PropacetamolUDP-glucuronosyltransferase 1-9enzyme
PropacetamolUDP-glucuronosyltransferase 2B15enzyme
PropacetamolUDP-glucuronosyltransferase 1-10enzyme
PropacetamolSulfotransferase 1A1enzyme
PropacetamolSulfotransferase 1A3/1A4enzyme
PropacetamolEstrogen sulfotransferaseenzyme
PropacetamolBile salt sulfotransferaseenzyme
PropacetamolArylamine N-acetyltransferase 2enzyme
PropacetamolCytochrome P450 2C9enzyme
PropacetamolCytochrome P450 3A4enzyme
Salicylic acidSerum albumincarrier
Salicylic acidProstaglandin G/H synthase 1target
Salicylic acidProstaglandin G/H synthase 2target
Salicylic acidAldo-keto reductase family 1 member C1target
Salicylic acidSolute carrier family 22 member 6transporter
Salicylic acidSolute carrier family 22 member 10transporter
Salicylic acidSolute carrier family 22 member 8transporter
Salicylic acidSolute carrier family 22 member 11transporter
Salicylic acidSolute carrier organic anion transporter family member 2B1transporter
Salicylic acidMonocarboxylate transporter 1transporter
Salicylic acidSolute carrier family 22 member 7transporter
Salicylic acidCytochrome P450 2C9enzyme
SalsalateProstaglandin G/H synthase 1target
SalsalateProstaglandin G/H synthase 2target
SulfasalazineAcetyl-CoA acetyltransferase, mitochondrialtarget
SulfasalazineCystine/glutamate transportertarget
SulfasalazineATP-binding cassette sub-family G member 2transporter
SulfasalazineCanalicular multispecific organic anion transporter 1transporter
SulfasalazineInhibitor of nuclear factor kappa-B kinase subunit alphatarget
SulfasalazineInhibitor of nuclear factor kappa-B kinase subunit betatarget
SulfasalazineProstaglandin G/H synthase 2target
SulfasalazinePeroxisome proliferator-activated receptor gammatarget
SulfasalazineProstaglandin G/H synthase 1target
SulfasalazineArachidonate 5-lipoxygenasetarget
SulfasalazineProton-coupled folate transportertransporter
SulfasalazineThromboxane-A synthasetarget
SulfasalazinePhospholipase A2target
SulfasalazineSolute carrier organic anion transporter family member 1B1transporter
SulfasalazineSolute carrier organic anion transporter family member 1B3transporter
SulfasalazineSolute carrier organic anion transporter family member 2B1transporter
SulindacProstaglandin G/H synthase 2target
SulindacAldose reductasetarget
SulindacProstaglandin G/H synthase 1target
SulindacMitogen-activated protein kinase 3target
SulindacPeroxisome proliferator-activated receptor deltatarget
SulindacProstaglandin D2 receptor 2target
SulindacSerum albumincarrier
SulindacSolute carrier family 22 member 6transporter
SulindacCytochrome P450 1A1enzyme
SulindacAldo-keto reductase family 1 member B10target
SuprofenProstaglandin G/H synthase 1target
SuprofenProstaglandin G/H synthase 2target
SuprofenCytochrome P450 2C9enzyme
SuprofenUDP-glucuronosyltransferase 1-1enzyme
SuprofenSolute carrier family 22 member 12transporter
SuprofenUDP-glucuronosyltransferase 2B7enzyme
SuprofenSerum albumincarrier
ZaltoprofenUDP-glucuronosyltransferase 2B7enzyme
ZaltoprofenCytochrome P450 2C9enzyme
ZaltoprofenProstaglandin G/H synthase 1enzyme
TenoxicamProstaglandin G/H synthase 1target
TenoxicamProstaglandin G/H synthase 2target
TenoxicamCytochrome P450 2C9enzyme
TenoxicamSolute carrier family 22 member 8transporter
Tiaprofenic acidProstaglandin G/H synthase 2target
Tiaprofenic acidProstaglandin G/H synthase 1target
Tolfenamic acidProstaglandin G/H synthase 1target
Tolfenamic acidProstaglandin G/H synthase 2target
Tolfenamic acidCytochrome P450 3A4enzyme
TolmetinProstaglandin G/H synthase 1target
TolmetinProstaglandin G/H synthase 2target
TolmetinSolute carrier family 22 member 6transporter
TolmetinTryptophan 2,3-dioxygenaseenzyme
TolmetinMyeloperoxidaseenzyme
TolmetinSerum albumincarrier
Trolamine salicylateProstaglandin G/H synthase 1target
Trolamine salicylateProstaglandin G/H synthase 2target
ZomepiracProstaglandin D2 receptor 2target
ZomepiracCytochrome P450 3A4enzyme
ZomepiracSerum albumincarrier