Calcium-Regulating Hormones and Agents

Hormones and molecules with calcium regulating hormone-like actions that modulate OSTEOLYSIS and other extra-skeletal activities to maintain calcium homeostasis.
DrugDrug NameDrug Description
DB00017Salmon CalcitoninA synthetic peptide form of calcitonin used to inhibit bone resorption in the treatment of hypercalcemia, osteoporosis, and Paget's disease.
DB00136CalcitriolAn active metabolite of vitamin D that is used to treat hyperparathyroidism and is also used in dialysis patients to combat hypocalcemia.
DB00153ErgocalciferolA vitamin found in many supplement products.
DB00169CholecalciferolA form of Vitamin D used in the treatment of specific medical conditions such as refractory rickets, hypoparathyroidism, and familial hypophosphatemia, as well as osteoporosis and chronic kidney disease.
DB00270IsradipineA dihydropyridine calcium channel blocker used for the treatment of hypertension.
DB00343DiltiazemA calcium channel blocker used to treat hypertension and to manage chronic stable angina.
DB00381AmlodipineA calcium channel blocker used to treat hypertension and angina.
DB00393NimodipineA calcium channel blocker used to improve neurological outcomes in patients with subarachnoid hemorrhage due to a ruptured intracranial aneurysm.
DB00401NisoldipineA calcium channel blocker used as monotherapy or combined with other drugs for the treatment of hypertension.
DB00528LercanidipineFor the treatment of Hypertension, management of angina pectoris and Raynaud's syndrome
DB00555LamotrigineA phenyltriazine antiepileptic used to treat some types of epilepsy and bipolar I disorder.
DB00568CinnarizineFor the treatment of vertigo/meniere's disease, nausea and vomiting, motion sickness and also useful for vestibular symptoms of other origins.
DB00622NicardipineA calcium channel blocker used for the short-term treatment of hypertension and chronic stable angina.
DB00653Magnesium sulfateA drug used to treat convulsions during pregnancy, nephritis in children, magnesium deficiency, and tetany.
DB00884Risedronic acidA bisphosphonate used to treat osteoporosis and Paget's disease.
DB00909ZonisamideA sulfonamide anticonvulsant used to treat partial seizures.
DB01012CinacalcetA calcium sensing receptor agonist used to treat secondary hyperparathyroidism in chronic kidney disease and hypercalcemia in parathyroid carcinoma.
DB01023FelodipineA calcium channel blocker used to treat hypertension.
DB01054NitrendipineFor the treatment of mild to moderate hypertension
DB01074PerhexilineFor the management of severe angina pectoris.
DB01115NifedipineA dihydropyridine calcium channel blocker indicated for the management of several subtypes of angina pectoris, and hypertension.
DB01136CarvedilolA non selective beta-adrenergic antagonist used to treat mild to severe chronic heart failure, hypertension, and left ventricular dysfunction following myocardial infarction in clinically stable patients.
DB01244BepridilFor the treatment of hypertension, and chronic stable angina (classic effort-associated angina).
DB01373CalciumA mineral found in over-the-counter supplements or prescription formulations used for the treatment of specific medical conditions related to calcium deficiency.
DB01388MibefradilFor the treatment of angina and high blood pressure.
DB01427AmrinoneA positive inotropic agent and phosphodiesterase inhibitor used in the management of treatment of congestive heart failure.
DB04825PrenylaminePrenylamine was withdrawn from the Canadian, US, and UK markets in 1988 due to concerns regarding cardiac arrhythmias.
DB04841FlunarizineA selective calcium-entry blocker used as migraine prophylaxis in patients with severe and frequent episodes who have not responded adequately to more common treatments.
DB04920ClevidipineA dihydropyridine L-type calcium channel blocker used to lower blood pressure when oral antihypertensive therapy is not feasible or not desirable.
DB04957AzimilideInvestigated for use/treatment in arrhythmia and atrial fibrillation.
DB05260Gallium nitrateA medication indicated for cancer-related hypercalcemia.
DB05829Parathyroid hormoneAn analog of human parathyroid hormone (PTH) used to treat hypocalcemia caused by hypoparathyroidism.
DB06283ZiconotideAn N-type calcium channel antagonist used to manage patients with severe chronic pain who cannot tolerate, or who have not responded adequately to other treatments such as intrathecal morphine and systemic analgesics.
DB06285TeriparatideA recombinant parathyroid hormone used for the treatment of osteoporosis.
DB06446DotarizineInvestigated for use/treatment in migraine and cluster headaches.
DB06712NilvadipineFor the management of vasospastic angina, chronic stable angina and hypertension.
DB06810PlicamycinFor the treatment of testicular cancer, as well as hypercalcemia and hypercalciuria associated with a variety of advanced forms of cancer.
DB07615TranilastFor the treatment of bronchial asthma, keloid and hypertrophic scar, and allergic disorders such as asthma, allergic rhinitis and atopic dermatitis.
DB08162FasudilFasudil has been investigated in Carotid Stenosis.
DB08980FendilineFendiline is a coronary vasodilator which inhibits calcium function in muscle cells in excitation-contraction coupling. It has been proposed as an antiarrhythmic and antianginal agent. Fendiline is non-selective.
DB08992EperisoneEperisone is an antispasmodic drug which relaxes both skeletal muscles and vascular smooth muscles, and demonstrates a variety of effects such as reduction of myotonia, improvement of circulation, and suppression...
DB09090PinaveriumA spasmolytic agent used for the symptomatic treatment of irritable bowel syndrome (IBS) and functional disorders of the biliary tract.
DB09216Tolfenamic acidIn the information for tolfenamic acid, it is stated that this drug, being an NSAID, is effective in treating the pain associated with the acute attack of migraines in adults.
DB09227BarnidipineIndicated for the treatment of mild to moderate essential hypertension and management of chronic stable angina.
DB09231BenidipineBenidipine is a potent and long-lasting drug indicated for the treatment of cardiovascular diseases such as hypertension, renoparenchymal hypertension and angina pectoris.
DB09232CilnidipineCilnidipine is indicated for the management of hypertension for end-organ protection. It is reported to be useful in elderly patients and in those with diabetes and albuminuria. Cilnidipine has been...
DB09234DarodipineDarodipine is a calcium channel blocker.
DB09235EfonidipineFor the treatment of hypertension.
DB09236LacidipineIndicated for the treatment of hypertension either alone or in combination with other antihypertensive agents, including β-adrenoceptor antagonists, diuretics, and ACE-inhibitors .
DB09238ManidipineFor the treatment of hypertension.
DB09239NiguldipineNiguldipine is a calcium channel blocker drug (CCB) with a1-adrenergic antagonist properties.
DB09240NiludipineNiludipine is a calcium channel blocker.
DB11960CarboxyamidotriazoleCarboxyamidotriazole has been used in trials studying the treatment of Lymphoma, Lung Cancer, Breast Cancer, Kidney Cancer, and Ovarian Cancer, among others.
DB12092NaftopidilNaftopidil has been investigated for the treatment of Disorder of Urinary Stent.
DB12093TetrahydropalmatineTetrahydropalmatine is under investigation in clinical trial NCT02118610 (Treatment of Schizophrenia With L-tetrahydropalmatine (l-THP): a Novel Dopamine Antagonist With Anti-inflammatory and Antiprotozoal Activity).
DB12923GallopamilGallopamil has been used in trials studying the treatment of Asthma.
DB13488BencyclaneA vasodilator agent found to be effective in a variety of peripheral circulation disorders. It has various other potentially useful pharmacological effects. Its mechanism may involve block of calcium channels.
DB13500OtiloniumNot Annotated
DB13725TerodilineNot Annotated
DB13742ElcatoninNot Annotated
DB13766LidoflazineNot Annotated
DB13835CaroverineNot Annotated
DB13950WIN 55212-2WIN 55,212-2 is a chemical described as an aminoalkylindole derivative, which produces effects similar to those of cannabinoids such as tetrahydrocannabinol (THC) but has an entirely different chemical structure. It...
DB14063DexverapamilNot Annotated
DB14064EmopamilPrevents renal injury after warm & cold ischemia.
DB14065LomerizineUsed to treat migraines.
DB14066TetrandrineNot Annotated
DB14068DexniguldipineNot Annotated
DB15366SOR-C13SOR-C13 is under investigation in clinical trial NCT01578564 (Safety and Tolerability Study of SOR-C13 in Subjects With Advanced Cancers Commonly Known to Express the TRPV6 Channel).
DrugDrug NameTargetType
DB00017Salmon CalcitoninCalcitonin receptortarget
DB00136CalcitriolVitamin D3 receptortarget
DB00136Calcitriol1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrialenzyme
DB00136CalcitriolCytochrome P450 3A4enzyme
DB00136CalcitriolHomeobox protein Hox-A10target
DB00136CalcitriolVitamin D-binding proteincarrier
DB00153ErgocalciferolVitamin D3 receptortarget
DB00153Ergocalciferol1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrialenzyme
DB00153Ergocalciferol25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrialenzyme
DB00153ErgocalciferolSterol 26-hydroxylase, mitochondrialenzyme
DB00153ErgocalciferolVitamin D 25-hydroxylaseenzyme
DB00153ErgocalciferolVitamin D-binding proteincarrier
DB00153ErgocalciferolVoltage-dependent calcium channeltarget
DB00153ErgocalciferolRibulose-phosphate 3-epimeraseenzyme
DB00153ErgocalciferolCholesterol side-chain cleavage enzyme, mitochondrialenzyme
DB00169CholecalciferolVitamin D-binding proteincarrier
DB00169CholecalciferolCholesterol side-chain cleavage enzyme, mitochondrialenzyme
DB00169CholecalciferolVitamin D 25-hydroxylaseenzyme
DB00169CholecalciferolSterol 26-hydroxylase, mitochondrialenzyme
DB00169CholecalciferolCytochrome P450 2J2enzyme
DB00169CholecalciferolCytochrome P450 3A4enzyme
DB00169CholecalciferolVitamin D3 receptortarget
DB00169CholecalciferolCytochrome P450 1A1enzyme
DB00169CholecalciferolCytochrome P450 2C8enzyme
DB00270IsradipineVoltage-dependent calcium channel subunit alpha-2/delta-1target
DB00270IsradipineVoltage-dependent L-type calcium channel subunit alpha-1Ctarget
DB00270IsradipineCytochrome P450 3A4enzyme
DB00270IsradipineVoltage-dependent T-type calcium channel subunit alpha-1Htarget
DB00270IsradipineVoltage-dependent calcium channel subunit alpha-2/delta-2target
DB00270IsradipineVoltage-dependent L-type calcium channel subunit beta-2target
DB00270IsradipineVoltage-dependent L-type calcium channel subunit alpha-1Dtarget
DB00270IsradipineVoltage-dependent L-type calcium channel subunit alpha-1Starget
DB00270IsradipineBile salt export pumptransporter
DB00343DiltiazemVoltage-dependent calcium channel gamma-1 subunittarget
DB00343DiltiazemCytochrome P450 3A4enzyme
DB00343DiltiazemCytochrome P450 2C19enzyme
DB00343DiltiazemCytochrome P450 2D6enzyme
DB00343DiltiazemCytochrome P450 3A5enzyme
DB00343DiltiazemCytochrome P450 3A7enzyme
DB00343DiltiazemP-glycoprotein 1transporter
DB00343DiltiazemCytochrome P450 2C8enzyme
DB00343DiltiazemSerum albumincarrier
DB00343DiltiazemAlpha-1-acid glycoprotein 1carrier
DB00343DiltiazemVoltage-dependent L-type calcium channel subunit alpha-1Ctarget
DB00381AmlodipineCarbonic anhydrase 1target
DB00381AmlodipineCytochrome P450 3A4enzyme
DB00381AmlodipineVoltage-dependent L-type calcium channel subunit alpha-1Ctarget
DB00381AmlodipineCytochrome P450 1A1enzyme
DB00381AmlodipineCytochrome P450 2B6enzyme
DB00381AmlodipineVoltage-dependent N-type calcium channel subunit alpha-1Btarget
DB00381AmlodipineVoltage-dependent L-type calcium channel subunit beta-1target
DB00381AmlodipineVoltage-dependent calcium channel subunit alpha-2/delta-3target
DB00381AmlodipineCytochrome P450 3A5enzyme
DB00381AmlodipineP-glycoprotein 1transporter
DB00381AmlodipineCytochrome P450 2C8enzyme
DB00381AmlodipineCytochrome P450 2D6enzyme
DB00381AmlodipineSphingomyelin phosphodiesterasetarget
DB00381AmlodipineVoltage-dependent T-type calcium channel subunit alpha-1Itarget
DB00381AmlodipineVoltage-dependent N-type calcium channeltarget
DB00393NimodipineCytochrome P450 3A4enzyme
DB00393NimodipineMineralocorticoid receptortarget
DB00393NimodipineVoltage-dependent L-type calcium channel subunit alpha-1Dtarget
DB00393NimodipineVoltage-dependent L-type calcium channel subunit alpha-1Starget
DB00393NimodipineVoltage-dependent L-type calcium channel subunit alpha-1Ctarget
DB00393NimodipineVoltage-dependent L-type calcium channel subunit beta-2target
DB00393NimodipineVoltage-dependent L-type calcium channel subunit alpha-1Ftarget
DB00393NimodipineVoltage-dependent L-type calcium channel subunit beta-1target
DB00393NimodipineVoltage-dependent L-type calcium channel subunit beta-3target
DB00393NimodipineVoltage-dependent L-type calcium channel subunit beta-4target
DB00393NimodipineAryl hydrocarbon receptortarget
DB00401NisoldipineCytochrome P450 3A4enzyme
DB00401NisoldipineVoltage-dependent L-type calcium channel subunit alpha-1Dtarget
DB00401NisoldipineVoltage-dependent L-type calcium channel subunit alpha-1Starget
DB00401NisoldipineVoltage-dependent L-type calcium channel subunit alpha-1Ctarget
DB00401NisoldipineVoltage-dependent calcium channel subunit alpha-2/delta-1target
DB00401NisoldipineVoltage-dependent L-type calcium channel subunit beta-2target
DB00401NisoldipineCytochrome P450 3A5enzyme
DB00401NisoldipineCytochrome P450 3A7enzyme
DB00401NisoldipineP-glycoprotein 1transporter
DB00528LercanidipineVoltage-dependent calcium channel gamma-1 subunittarget
DB00528LercanidipineCytochrome P450 3A4enzyme
DB00528LercanidipineCytochrome P450 3A5enzyme
DB00528LercanidipineCytochrome P450 3A7enzyme
DB00528LercanidipineCytochrome P450 2D6enzyme
DB00555LamotrigineSodium channel protein type 2 subunit alphatarget
DB00555LamotrigineUDP-glucuronosyltransferase 1-4enzyme
DB00555LamotrigineP-glycoprotein 1transporter
DB00555LamotrigineUDP-glucuronosyltransferase 1-3enzyme
DB00555LamotrigineDihydrofolate reductaseenzyme
DB00555Lamotrigine5-hydroxytryptamine receptor 3Atarget
DB00555LamotrigineVoltage-dependent R-type calcium channel subunit alpha-1E (CACNA1E)target
DB00555LamotrigineAdenosine receptor A1target
DB00555LamotrigineAdenosine receptor A2atarget
DB00555LamotrigineAlpha-1A adrenergic receptortarget
DB00555LamotrigineAlpha-2A adrenergic receptortarget
DB00555LamotrigineBeta-1 adrenergic receptortarget
DB00555LamotrigineD(1) dopamine receptortarget
DB00555LamotrigineDopamine D2 receptortarget
DB00555LamotrigineGABA-A receptor (anion channel)target
DB00555LamotrigineGABA-A receptor (benzodiazepine site)target
DB00555LamotrigineHistamine H1 receptortarget
DB00555LamotrigineKappa-type opioid receptortarget
DB00555LamotrigineMuscarinic acetylcholine receptortarget
DB00555Lamotrigine5-hydroxytryptamine receptor 2Atarget
DB00555LamotrigineUDP-glucuronosyltransferase 1-1enzyme
DB00555LamotrigineSolute carrier family 22 member 2transporter
DB00568CinnarizineHistamine H1 receptortarget
DB00568CinnarizineDopamine D2 receptortarget
DB00568CinnarizineVoltage-dependent T-type calcium channel subunit alpha-1Htarget
DB00568CinnarizineCytochrome P450 2D6enzyme
DB00568CinnarizineCytochrome P450 2B6enzyme
DB00568CinnarizineCytochrome P450 2C9enzyme
DB00568CinnarizineCytochrome P450 1A1enzyme
DB00568CinnarizineCytochrome P450 1A2enzyme
DB00568CinnarizineCytochrome P450 2A6enzyme
DB00568CinnarizineVoltage-dependent L-type calcium channel subunit alpha-1Ctarget
DB00568CinnarizineVoltage-dependent L-type calcium channel subunit alpha-1Starget
DB00568CinnarizineVoltage-dependent L-type calcium channel subunit alpha-1Ftarget
DB00568CinnarizineVoltage-dependent L-type calcium channel subunit alpha-1Dtarget
DB00568CinnarizineVoltage-dependent T-type calcium channel subunit alpha-1Gtarget
DB00568CinnarizineVoltage-dependent T-type calcium channel subunit alpha-1Itarget
DB00568CinnarizineD(1) dopamine receptortarget
DB00568CinnarizineMuscarinic acetylcholine receptortarget
DB00568CinnarizineCytochrome P450 3A4enzyme
DB00622NicardipineVoltage-dependent L-type calcium channel subunit alpha-1Ctarget
DB00622NicardipineCytochrome P450 3A4enzyme
DB00622NicardipineCytochrome P450 2C19enzyme
DB00622NicardipineCytochrome P450 2C8enzyme
DB00622NicardipineCytochrome P450 2D6enzyme
DB00622NicardipineCalcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1Btarget
DB00622NicardipineCalcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1Atarget
DB00622NicardipineAlpha-1A adrenergic receptortarget
DB00622NicardipineAlpha-1D adrenergic receptortarget
DB00622NicardipineAlpha-1B adrenergic receptortarget
DB00622NicardipineMuscarinic acetylcholine receptor M1target
DB00622NicardipineMuscarinic acetylcholine receptor M2target
DB00622NicardipineMuscarinic acetylcholine receptor M3target
DB00622NicardipineMuscarinic acetylcholine receptor M4target
DB00622NicardipineMuscarinic acetylcholine receptor M5target
DB00622NicardipineVoltage-dependent calcium channel subunit alpha-2/delta-1target
DB00622NicardipineVoltage-dependent L-type calcium channel subunit beta-2target
DB00622NicardipineVoltage-dependent L-type calcium channel subunit alpha-1Dtarget
DB00622NicardipineCalmodulintarget
DB00622NicardipineP-glycoprotein 1transporter
DB00622NicardipineCytochrome P450 2B6enzyme
DB00622NicardipineCytochrome P450 2E1enzyme
DB00622NicardipineCytochrome P450 3A5enzyme
DB00622NicardipineSolute carrier organic anion transporter family member 1B1transporter
DB00622NicardipineBile salt export pumptransporter
DB00622NicardipineCytochrome P450 2C9enzyme
DB00653Magnesium sulfateVoltage-dependent calcium channel gamma-1 subunittarget
DB00653Magnesium sulfateVoltage-dependent calcium channel subunit alpha-2/delta-1target
DB00653Magnesium sulfateVoltage-dependent L-type calcium channel subunit alpha-1Ctarget
DB00653Magnesium sulfateVoltage-dependent L-type calcium channel subunit beta-1target
DB00653Magnesium sulfateVoltage-dependent L-type calcium channel subunit beta-2target
DB00653Magnesium sulfateVoltage-dependent L-type calcium channel subunit alpha-1Starget
DB00884Risedronic acidFarnesyl pyrophosphate synthasetarget
DB00884Risedronic acidHydroxylapatitetarget
DB00884Risedronic acidProstaglandin G/H synthase 2enzyme
DB00909ZonisamideSodium channel protein type 1 subunit alphatarget
DB00909ZonisamideCarbonic anhydrase 1target
DB00909ZonisamideVoltage-dependent T-type calcium channel subunit alpha-1Gtarget
DB00909ZonisamideCytochrome P450 3A4enzyme
DB00909ZonisamideAldehyde oxidaseenzyme
DB00909ZonisamideAmine oxidase [flavin-containing] Btarget
DB00909ZonisamideCarbonic anhydrase 2target
DB00909ZonisamideCarbonic anhydrase 3target
DB00909ZonisamideCarbonic anhydrase 4target
DB00909ZonisamideCarbonic anhydrase 5A, mitochondrialtarget
DB00909ZonisamideCarbonic anhydrase 5B, mitochondrialtarget
DB00909ZonisamideCarbonic anhydrase 6target
DB00909ZonisamideCarbonic anhydrase 7target
DB00909ZonisamideCarbonic anhydrase-related proteintarget
DB00909ZonisamideCarbonic anhydrase 9target
DB00909ZonisamideCarbonic anhydrase-related protein 10target
DB00909ZonisamideCarbonic anhydrase-related protein 11target
DB00909ZonisamideCarbonic anhydrase 12target
DB00909ZonisamideCarbonic anhydrase 13target
DB00909ZonisamideCarbonic anhydrase 14target
DB00909ZonisamideVoltage-dependent T-type calcium channel subunit alpha-1Htarget
DB00909ZonisamideVoltage-dependent T-type calcium channel subunit alpha-1Itarget
DB00909ZonisamideSodium channel protein type 2 subunit alphatarget
DB00909ZonisamideSodium channel protein type 3 subunit alphatarget
DB00909ZonisamideSodium channel protein type 4 subunit alphatarget
DB00909ZonisamideSodium channel protein type 5 subunit alphatarget
DB00909ZonisamideSodium channel protein type 9 subunit alphatarget
DB00909ZonisamideSodium channel protein type 11 subunit alphatarget
DB00909ZonisamideSodium channel subunit beta-1target
DB00909ZonisamideSodium channel subunit beta-2target
DB00909ZonisamideSodium channel subunit beta-3target
DB00909ZonisamideSodium channel subunit beta-4target
DB00909ZonisamideAmine oxidase [flavin-containing] Atarget
DB00909ZonisamideCytochrome P450 2C19enzyme
DB00909ZonisamideUDP-glucuronosyltransferase 1-1enzyme
DB00909ZonisamideCytochrome P450 3A5enzyme
DB01012CinacalcetExtracellular calcium-sensing receptortarget
DB01012CinacalcetCytochrome P450 3A4enzyme
DB01012CinacalcetCytochrome P450 2D6enzyme
DB01012CinacalcetCytochrome P450 1A2enzyme
DB01023FelodipineVoltage-dependent calcium channel subunit alpha-2/delta-1target
DB01023FelodipineCalmodulintarget
DB01023FelodipineCytochrome P450 3A4enzyme
DB01023FelodipineVoltage-dependent L-type calcium channel subunit alpha-1Ctarget
DB01023FelodipineVoltage-dependent L-type calcium channel subunit beta-2target
DB01023FelodipineCytochrome P450 2C8enzyme
DB01023FelodipineCalcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1Btarget
DB01023FelodipineCalcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1Atarget
DB01023FelodipineVoltage-dependent T-type calcium channel subunit alpha-1Htarget
DB01023FelodipineVoltage-dependent calcium channel subunit alpha-2/delta-2target
DB01023FelodipineTroponin C, skeletal muscletarget
DB01023FelodipineTroponin C, slow skeletal and cardiac musclestarget
DB01023FelodipineMineralocorticoid receptortarget
DB01023FelodipineVoltage-dependent L-type calcium channel subunit alpha-1Dtarget
DB01023FelodipineVoltage-dependent L-type calcium channel subunit alpha-1Starget
DB01023FelodipineCytochrome P450 3A5enzyme
DB01023FelodipineCytochrome P450 3A7enzyme
DB01023FelodipineP-glycoprotein 1transporter
DB01023FelodipineCytochrome P450 2C9enzyme
DB01023FelodipineCytochrome P450 2D6enzyme
DB01023FelodipineBile salt export pumptransporter
DB01054NitrendipineVoltage-dependent calcium channel gamma-1 subunittarget
DB01054NitrendipineCytochrome P450 3A4enzyme
DB01054NitrendipineVoltage-dependent T-type calcium channel subunit alpha-1Htarget
DB01054NitrendipineVoltage-dependent calcium channel subunit alpha-2/delta-2target
DB01054NitrendipineVoltage-dependent L-type calcium channel subunit alpha-1Dtarget
DB01054NitrendipineVoltage-dependent L-type calcium channel subunit alpha-1Starget
DB01054NitrendipineVoltage-dependent L-type calcium channel subunit alpha-1Ctarget
DB01054NitrendipineVoltage-dependent calcium channel subunit alpha-2/delta-1target
DB01054NitrendipineVoltage-dependent L-type calcium channel subunit beta-2target
DB01054NitrendipineCytochrome P450 3A5enzyme
DB01054NitrendipineCytochrome P450 3A7enzyme
DB01054NitrendipineP-glycoprotein 1transporter
DB01054NitrendipineBile salt export pumptransporter
DB01074PerhexilineCarnitine O-palmitoyltransferase 1, liver isoformtarget
DB01074PerhexilineCarnitine O-palmitoyltransferase 2, mitochondrialtarget
DB01074PerhexilineCytochrome P450 2D6enzyme
DB01074PerhexilineCytochrome P450 2B6enzyme
DB01074PerhexilineCytochrome P450 3A4enzyme
DB01074PerhexilinePotassium voltage-gated channel subfamily H member 2target
DB01115NifedipineVoltage-dependent calcium channel subunit alpha-2/delta-1target
DB01115NifedipineCytochrome P450 3A4enzyme
DB01115NifedipineCytochrome P450 2E1enzyme
DB01115NifedipineCytochrome P450 2D6enzyme
DB01115NifedipineCalmodulintarget
DB01115NifedipineVoltage-dependent L-type calcium channel subunit alpha-1Dtarget
DB01115NifedipineVoltage-dependent L-type calcium channel subunit alpha-1Starget
DB01115NifedipineVoltage-dependent L-type calcium channel subunit alpha-1Ctarget
DB01115NifedipineVoltage-dependent L-type calcium channel subunit beta-2target
DB01115NifedipinePotassium voltage-gated channel subfamily A member 1target
DB01115NifedipineVoltage-dependent T-type calcium channel subunit alpha-1Htarget
DB01115NifedipineCytochrome P450 1A2enzyme
DB01115NifedipineCytochrome P450 2A6enzyme
DB01115NifedipineCytochrome P450 2C8enzyme
DB01115NifedipineCanalicular multispecific organic anion transporter 2transporter
DB01115NifedipineP-glycoprotein 1transporter
DB01115NifedipineCanalicular multispecific organic anion transporter 1transporter
DB01115NifedipineCytochrome P450 1A1enzyme
DB01115NifedipineCytochrome P450 2B6enzyme
DB01115NifedipineNuclear receptor subfamily 1 group I member 2target
DB01115NifedipineSolute carrier organic anion transporter family member 1B1transporter
DB01115NifedipineBile salt export pumptransporter
DB01115NifedipineCytochrome P450 2C9enzyme
DB01115NifedipineSerum albumincarrier
DB01115Nifedipinealpha1-acid glycoproteincarrier
DB01115NifedipineCytochrome P450 3A5enzyme
DB01136CarvedilolAlpha-1A adrenergic receptortarget
DB01136CarvedilolBeta-1 adrenergic receptortarget
DB01136CarvedilolNADH dehydrogenase [ubiquinone] 1 subunit C2target
DB01136CarvedilolBeta-2 adrenergic receptortarget
DB01136CarvedilolVascular endothelial growth factor Atarget
DB01136CarvedilolNatriuretic peptides Btarget
DB01136CarvedilolGap junction alpha-1 proteintarget
DB01136CarvedilolPotassium voltage-gated channel subfamily H member 2target
DB01136CarvedilolVascular cell adhesion protein 1target
DB01136CarvedilolCytochrome P450 2C9enzyme
DB01136CarvedilolCytochrome P450 2D6enzyme
DB01136CarvedilolXanthine dehydrogenase/oxidaseenzyme
DB01136CarvedilolP-glycoprotein 1transporter
DB01136CarvedilolCytochrome P450 1A2enzyme
DB01136CarvedilolCytochrome P450 3A4enzyme
DB01136CarvedilolCytochrome P450 1A1enzyme
DB01136CarvedilolCytochrome P450 2E1enzyme
DB01136CarvedilolAlpha-1D adrenergic receptortarget
DB01136CarvedilolAlpha-1B adrenergic receptortarget
DB01136CarvedilolAlpha-2C adrenergic receptortarget
DB01136CarvedilolAlpha-2B adrenergic receptortarget
DB01136CarvedilolAlpha-2A adrenergic receptortarget
DB01136CarvedilolE-selectintarget
DB01136CarvedilolHypoxia-inducible factor 1-alphatarget
DB01136CarvedilolInward rectifier potassium channel 4target
DB01136CarvedilolUDP-glucuronosyltransferase 1-1enzyme
DB01136CarvedilolSerum albumincarrier
DB01136CarvedilolUDP-glucuronosyltransferase 2B4enzyme
DB01136CarvedilolUDP-glucuronosyltransferase 2B7enzyme
DB01136CarvedilolInward rectifier potassium channel 2target
DB01244BepridilVoltage-dependent P/Q-type calcium channel subunit alpha-1Atarget
DB01244BepridilSodium/potassium-transporting ATPase subunit alpha-1target
DB01244BepridilPotassium voltage-gated channel subfamily KQT member 1target
DB01244BepridilTroponin C, slow skeletal and cardiac musclestarget
DB01244BepridilCalmodulintarget
DB01244BepridilVoltage-dependent T-type calcium channel subunit alpha-1Htarget
DB01244BepridilVoltage-dependent calcium channel subunit alpha-2/delta-2target
DB01244BepridilCalcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1Btarget
DB01244BepridilCalcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1Atarget
DB01244BepridilP-glycoprotein 1transporter
DB01244BepridilCytochrome P450 2D6enzyme
DB01244BepridilPotassium voltage-gated channel subfamily H member 2target
DB01244BepridilCytochrome P450 3A4enzyme
DB01373CalciumProtein S100-Btarget
DB01373CalciumCalpastatintarget
DB01373CalciumCartilage oligomeric matrix proteintarget
DB01373CalciumCalmodulintarget
DB01373CalciumSpectrin beta chain, non-erythrocytic 1target
DB01373CalciumVoltage-dependent L-type calcium channel subunit alpha-1Ctarget
DB01373CalciumTroponin C, skeletal muscletarget
DB01373CalciumTroponin C, slow skeletal and cardiac musclestarget
DB01373CalciumCalcium-transporting ATPase type 2C member 1target
DB01373CalciumAmiloride-sensitive amine oxidase [copper-containing]target
DB01373CalciumProtein S100-A13target
DB01373CalciumAlkaline phosphatase, placental typetarget
DB01373CalciumProtein S100-A8target
DB01373CalciumProtein S100-A9target
DB01373CalciumProtein S100-A2target
DB01373CalciumCeruloplasmintarget
DB01373CalciumBone morphogenetic protein 4target
DB01373CalciumMatrix Gla proteintarget
DB01373CalciumProtocadherin-19target
DB01373CalciumProgrammed cell death protein 6target
DB01388MibefradilVoltage-dependent T-type calcium channel subunit alpha-1Gtarget
DB01388MibefradilVoltage-dependent T-type calcium channel subunit alpha-1Htarget
DB01388MibefradilVoltage-dependent L-type calcium channel subunit alpha-1Ctarget
DB01388MibefradilVoltage-dependent L-type calcium channel subunit beta-1target
DB01388MibefradilCytochrome P450 3A4enzyme
DB01388MibefradilCytochrome P450 1A2enzyme
DB01388MibefradilCytochrome P450 2D6enzyme
DB01388MibefradilCytochrome P450 3A5enzyme
DB01388MibefradilCytochrome P450 3A7enzyme
DB01388MibefradilP-glycoprotein 1transporter
DB01388MibefradilVoltage-dependent T-type calcium channel subunit alpha-1Itarget
DB01388MibefradilVoltage-dependent L-type calcium channel subunit alpha-1Starget
DB01388MibefradilVoltage-dependent L-type calcium channel subunit alpha-1Ftarget
DB01388MibefradilVoltage-dependent L-type calcium channel subunit alpha-1Dtarget
DB01388MibefradilVoltage-dependent L-type calcium channel subunit beta-2target
DB01388MibefradilVoltage-dependent L-type calcium channel subunit beta-3target
DB01388MibefradilVoltage-dependent L-type calcium channel subunit beta-4target
DB01388MibefradilCytochrome P450 11B1, mitochondrialenzyme
DB01388MibefradilCytochrome P450 11B2, mitochondrialenzyme
DB01427AmrinonecAMP-specific 3',5'-cyclic phosphodiesterase 4Btarget
DB01427AmrinoneTumor necrosis factortarget
DB01427AmrinonecGMP-inhibited 3',5'-cyclic phosphodiesterase Atarget
DB01427AmrinonecGMP-inhibited 3',5'-cyclic phosphodiesterase Btarget
DB04825PrenylamineCalmodulintarget
DB04825PrenylamineMyosin light chain kinase 2, skeletal/cardiac muscletarget
DB04825PrenylamineCytochrome P450 3A4enzyme
DB04841FlunarizineHistamine H1 receptortarget
DB04841FlunarizineVoltage-dependent T-type calcium channel subunit alpha-1Gtarget
DB04841FlunarizineVoltage-dependent T-type calcium channel subunit alpha-1Htarget
DB04841FlunarizineVoltage-dependent T-type calcium channel subunit alpha-1Itarget
DB04841FlunarizineCalmodulintarget
DB04841FlunarizineCytochrome P450 2D6enzyme
DB04841FlunarizineCytochrome P450 2C9enzyme
DB04841FlunarizineCytochrome P450 1A1enzyme
DB04841FlunarizineCytochrome P450 1A2enzyme
DB04841FlunarizineCytochrome P450 2A6enzyme
DB04841FlunarizineCytochrome P450 3A4enzyme
DB04920ClevidipineVoltage-dependent L-type calcium channel subunit alpha-1Ftarget
DB04920ClevidipineVoltage-dependent L-type calcium channel subunit alpha-1Starget
DB04920ClevidipineVoltage-dependent L-type calcium channel subunit alpha-1Dtarget
DB04920ClevidipineVoltage-dependent L-type calcium channel subunit alpha-1Ctarget
DB04920ClevidipineCytochrome P450 2C9enzyme
DB04920ClevidipineCytochrome P450 2D6enzyme
DB04920ClevidipineCytochrome P450 2E1enzyme
DB04920ClevidipineCytochrome P450 2C19enzyme
DB04920ClevidipineCytochrome P450 3A4enzyme
DB04920ClevidipineCholinesteraseenzyme
DB04957AzimilidePotassium voltage-gated channel subfamily E member 1target
DB04957AzimilidePotassium voltage-gated channel subfamily KQT member 1target
DB04957AzimilidePotassium voltage-gated channel subfamily H member 2target
DB04957AzimilideCytochrome P450 1A1enzyme
DB04957AzimilideCytochrome P450 3A4enzyme
DB04957AzimilideCytochrome P450 3A5enzyme
DB04957AzimilideCytochrome P450 2D6enzyme
DB05260Gallium nitrateSerotransferrincarrier
DB05260Gallium nitrateRibonucleoside-diphosphate reductase subunit M2target
DB05260Gallium nitrateProtein-tyrosine-phosphatasetarget
DB05260Gallium nitrateInterleukin-1 betatarget
DB05260Gallium nitrateHydroxylapatitetarget
DB05260Gallium nitrateOsteocalcintarget
DB05260Gallium nitrateV-type proton ATPase subunit B, brain isoformtarget
DB05260Gallium nitrateTransferrin receptortransporter
DB05829Parathyroid hormoneParathyroid hormone/parathyroid hormone-related peptide receptortarget
DB05829Parathyroid hormoneParathyroid hormone 2 receptortarget
DB06283ZiconotideCytochrome P450 3A4enzyme
DB06285TeriparatideParathyroid hormone/parathyroid hormone-related peptide receptortarget
DB06446Dotarizine5-hydroxytryptamine receptor 2Atarget
DB06446Dotarizine5-hydroxytryptamine receptor 1Atarget
DB06446DotarizineVoltage-dependent P/Q-type calcium channel subunit alpha-1Atarget
DB06446Dotarizine5-hydroxytryptamine receptor 2Ctarget
DB06446DotarizineCytochrome P450 3A4enzyme
DB06712NilvadipineCytochrome P450 3A4enzyme
DB06712NilvadipineCytochrome P450 2A6enzyme
DB06712NilvadipineCytochrome P450 2C19enzyme
DB06712NilvadipineCytochrome P450 2C8enzyme
DB06712NilvadipineCytochrome P450 2E1enzyme
DB06712NilvadipineVoltage-dependent L-type calcium channel subunit alpha-1Ctarget
DB06712NilvadipineVoltage-dependent calcium channel subunit alpha-2/delta-1target
DB06712NilvadipineVoltage-dependent L-type calcium channel subunit beta-2target
DB06712NilvadipineVoltage-dependent L-type calcium channel subunit alpha-1Dtarget
DB06712NilvadipineVoltage-dependent L-type calcium channel subunit alpha-1Starget
DB06712NilvadipineVoltage-dependent calcium channel subunit alpha-2/delta-3target
DB06810PlicamycinDNAtarget
DB07615TranilastHematopoietic prostaglandin D synthasetarget
DB07615TranilastCytochrome P450 3A4enzyme
DB07615TranilastCytochrome P450 2C9enzyme
DB08162FasudilcAMP-dependent protein kinase inhibitor alphatarget
DB08162FasudilcAMP-dependent protein kinase catalytic subunit alphatarget
DB08162FasudilRho-associated protein kinase 1target
DB08162FasudilRho-associated protein kinase 2target
DB08980FendilineCytochrome P450 3A4enzyme
DB08992EperisoneCytochrome P450 3A4enzyme
DB09090PinaveriumVoltage-dependent L-type calcium channel subunit alpha-1Starget
DB09090PinaveriumCytochrome P450 3A4enzyme
DB09216Tolfenamic acidProstaglandin G/H synthase 1target
DB09216Tolfenamic acidProstaglandin G/H synthase 2target
DB09216Tolfenamic acidCytochrome P450 3A4enzyme
DB09227BarnidipineVoltage-dependent L-type calcium channel subunit alpha-1Ctarget
DB09227BarnidipineCytochrome P450 3A4enzyme
DB09231BenidipineVoltage-dependent L-type calcium channeltarget
DB09231BenidipineVoltage-dependent N-type calcium channel subunit alpha-1Btarget
DB09231BenidipineVoltage-dependent T-type calcium channeltarget
DB09231BenidipineCytochrome P450 3A4enzyme
DB09231BenidipineCytochrome P450 3A5enzyme
DB09232CilnidipineVoltage-dependent N-type calcium channel subunit alpha-1Btarget
DB09232CilnidipineVoltage-dependent L-type calcium channeltarget
DB09232CilnidipineCytochrome P450 3A4enzyme
DB09234DarodipineCytochrome P450 3A4enzyme
DB09235EfonidipineVoltage-dependent T-type calcium channel subunit alpha-1Itarget
DB09235EfonidipineVoltage-dependent L-type calcium channel subunit alpha-1Ctarget
DB09235EfonidipineCytochrome P450 3A4enzyme
DB09236LacidipineCytochrome P450 3A4enzyme
DB09236LacidipineSerum albumincarrier
DB09236LacidipineAlpha-1-acid glycoprotein 1carrier
DB09236LacidipineVoltage-dependent L-type calcium channeltarget
DB09238ManidipineVoltage-dependent L-type calcium channeltarget
DB09238ManidipineVoltage-dependent T-type calcium channeltarget
DB09238ManidipineCytochrome P450 2C9enzyme
DB09238ManidipineCytochrome P450 2D6enzyme
DB09238ManidipineCytochrome P450 1A1enzyme
DB09238ManidipineCytochrome P450 2B6enzyme
DB09238ManidipineCytochrome P450 2C19enzyme
DB09238ManidipineCytochrome P450 3A4enzyme
DB09239NiguldipineAlpha-1A adrenergic receptortarget
DB09239NiguldipineCytochrome P450 3A4enzyme
DB09240NiludipineCytochrome P450 3A4enzyme
DB11960CarboxyamidotriazoleCytochrome P450 3A4enzyme
DB12092NaftopidilCytochrome P450 3A4enzyme
DB12093TetrahydropalmatineDopamine D1 receptortarget
DB12093TetrahydropalmatineDopamine D2 receptortarget
DB12093TetrahydropalmatineCytochrome P450 3A4enzyme
DB12923GallopamilCytochrome P450 3A4enzyme
DB13488BencyclaneCytochrome P450 3A4enzyme
DB13500OtiloniumCytochrome P450 3A4enzyme
DB13725TerodilineCytochrome P450 3A4enzyme
DB13766LidoflazineCytochrome P450 3A4enzyme
DB13835CaroverineCytochrome P450 3A4enzyme
DB13950WIN 55212-2Cytochrome P450 3A4enzyme
DB14063DexverapamilP-glycoprotein 1target
DB14063DexverapamilCytochrome P450 3A4enzyme
DB14064EmopamilP-glycoprotein 1target
DB14064EmopamilCytochrome P450 3A4enzyme
DB14065LomerizineP-glycoprotein 1target
DB14065LomerizineCytochrome P450 3A4enzyme
DB14066TetrandrineP-glycoprotein 1target
DB14066TetrandrineCytochrome P450 3A4enzyme
DB14068DexniguldipineP-glycoprotein 1target
DB14068DexniguldipineCytochrome P450 3A4enzyme