Calcium-Regulating Hormones and Agents
- Calcium-Regulating Hormones and Agents
- Accession Number
Hormones and molecules with calcium regulating hormone-like actions that modulate OSTEOLYSIS and other extra-skeletal activities to maintain calcium homeostasis.
Drug Drug Description Salmon calcitonin A synthetic peptide form of calcitonin used to inhibit bone resorption in the treatment of hypercalcemia, osteoporosis, and Paget's disease. Calcitriol An active metabolite of vitamin D that is used to treat hyperparathyroidism and is also used in dialysis patients to combat hypocalcemia. Ergocalciferol A vitamin found in many supplement products. Cholecalciferol A form of Vitamin D used in the treatment of specific medical conditions such as refractory rickets, hypoparathyroidism, and familial hypophosphatemia, as well as osteoporosis and chronic kidney disease. Isradipine A dihydropyridine calcium channel blocker used for the treatment of hypertension. Diltiazem A calcium channel blocker used to treat hypertension and to manage chronic stable angina. Amlodipine A calcium channel blocker used to treat hypertension and angina. Nimodipine A calcium channel blocker used to improve neurological outcomes in patients with subarachnoid hemorrhage due to a ruptured intracranial aneurysm. Nisoldipine A calcium channel blocker used as monotherapy or combined with other drugs for the treatment of hypertension. Lercanidipine For the treatment of Hypertension, management of angina pectoris and Raynaud's syndrome Lamotrigine A phenyltriazine antiepileptic used to treat some types of epilepsy and bipolar I disorder. Cinnarizine For the treatment of vertigo/meniere's disease, nausea and vomiting, motion sickness and also useful for vestibular symptoms of other origins. Nicardipine A calcium channel blocker used for the short-term treatment of hypertension and chronic stable angina. Magnesium sulfate A drug used to treat convulsions during pregnancy, nephritis in children, magnesium deficiency, and tetany. Risedronic acid A bisphosphonate used to treat osteoporosis and Paget's disease. Zonisamide A sulfonamide anticonvulsant used to treat partial seizures. Cinacalcet A calcium sensing receptor agonist used to treat secondary hyperparathyroidism in chronic kidney disease and hypercalcemia in parathyroid carcinoma. Felodipine A calcium channel blocker used to treat hypertension. Nitrendipine For the treatment of mild to moderate hypertension Perhexiline For the management of severe angina pectoris. Nifedipine A dihydropyridine calcium channel blocker indicated for the management of several subtypes of angina pectoris, and hypertension. Carvedilol A non selective beta-adrenergic antagonist used to treat mild to severe chronic heart failure, hypertension, and left ventricular dysfunction following myocardial infarction in clinically stable patients. Bepridil For the treatment of hypertension, and chronic stable angina (classic effort-associated angina). Calcium A mineral found in over-the-counter supplements or prescription formulations used for the treatment of specific medical conditions related to calcium deficiency. Mibefradil For the treatment of angina and high blood pressure. Amrinone A positive inotropic agent and phosphodiesterase inhibitor used in the management of treatment of congestive heart failure. Prenylamine Prenylamine was withdrawn from the Canadian, US, and UK markets in 1988 due to concerns regarding cardiac arrhythmias. Flunarizine A selective calcium-entry blocker used as migraine prophylaxis in patients with severe and frequent episodes who have not responded adequately to more common treatments. Clevidipine A dihydropyridine L-type calcium channel blocker used to lower blood pressure when oral antihypertensive therapy is not feasible or not desirable. Azimilide Investigated for use/treatment in arrhythmia and atrial fibrillation. Gallium nitrate A medication indicated for cancer-related hypercalcemia. Parathyroid hormone An analog of human parathyroid hormone (PTH) used to treat hypocalcemia caused by hypoparathyroidism. Ziconotide An N-type calcium channel antagonist used to manage patients with severe chronic pain who cannot tolerate, or who have not responded adequately to other treatments such as intrathecal morphine and systemic analgesics. Teriparatide A recombinant parathyroid hormone used for the treatment of osteoporosis. Dotarizine Investigated for use/treatment in migraine and cluster headaches. Nilvadipine For the management of vasospastic angina, chronic stable angina and hypertension. Plicamycin For the treatment of testicular cancer, as well as hypercalcemia and hypercalciuria associated with a variety of advanced forms of cancer. Tranilast For the treatment of bronchial asthma, keloid and hypertrophic scar, and allergic disorders such as asthma, allergic rhinitis and atopic dermatitis. Fasudil Fasudil has been investigated in Carotid Stenosis. Fendiline Fendiline is a coronary vasodilator which inhibits calcium function in muscle cells in excitation-contraction coupling. It has been proposed as an antiarrhythmic and antianginal agent. Fendiline is non-selective. Eperisone Eperisone is an antispasmodic drug which relaxes both skeletal muscles and vascular smooth muscles, and demonstrates a variety of effects such as reduction of myotonia, improvement of circulation, and suppression... Pinaverium A spasmolytic agent used for the symptomatic treatment of irritable bowel syndrome (IBS) and functional disorders of the biliary tract. Tolfenamic acid In the information for tolfenamic acid, it is stated that this drug, being an NSAID, is effective in treating the pain associated with the acute attack of migraines in adults. Barnidipine Indicated for the treatment of mild to moderate essential hypertension and management of chronic stable angina. Benidipine Benidipine is a potent and long-lasting drug indicated for the treatment of cardiovascular diseases such as hypertension, renoparenchymal hypertension and angina pectoris. Cilnidipine Cilnidipine is indicated for the management of hypertension for end-organ protection. It is reported to be useful in elderly patients and in those with diabetes and albuminuria. Cilnidipine has been... Darodipine Darodipine is a calcium channel blocker. Efonidipine For the treatment of hypertension. Lacidipine Indicated for the treatment of hypertension either alone or in combination with other antihypertensive agents, including β-adrenoceptor antagonists, diuretics, and ACE-inhibitors . Manidipine For the treatment of hypertension. Niguldipine Niguldipine is a calcium channel blocker drug (CCB) with a1-adrenergic antagonist properties. Niludipine Niludipine is a calcium channel blocker. Carboxyamidotriazole Carboxyamidotriazole has been used in trials studying the treatment of Lymphoma, Lung Cancer, Breast Cancer, Kidney Cancer, and Ovarian Cancer, among others. Naftopidil Naftopidil has been investigated for the treatment of Disorder of Urinary Stent. Tetrahydropalmatine Tetrahydropalmatine is under investigation in clinical trial NCT02118610 (Treatment of Schizophrenia With L-tetrahydropalmatine (l-THP): a Novel Dopamine Antagonist With Anti-inflammatory and Antiprotozoal Activity). Gallopamil Gallopamil has been used in trials studying the treatment of Asthma. Bencyclane A vasodilator agent found to be effective in a variety of peripheral circulation disorders. It has various other potentially useful pharmacological effects. Its mechanism may involve block of calcium channels. Otilonium Not Annotated Terodiline Not Annotated Elcatonin Not Annotated Lidoflazine Not Annotated Caroverine Not Annotated WIN 55212-2 WIN 55,212-2 is a chemical described as an aminoalkylindole derivative, which produces effects similar to those of cannabinoids such as tetrahydrocannabinol (THC) but has an entirely different chemical structure. It... Dexverapamil Not Annotated Emopamil Prevents renal injury after warm & cold ischemia. Lomerizine Used to treat migraines. Tetrandrine Not Annotated Dexniguldipine Not Annotated SOR-C13 SOR-C13 is under investigation in clinical trial NCT01578564 (Safety and Tolerability Study of SOR-C13 in Subjects With Advanced Cancers Commonly Known to Express the TRPV6 Channel).
- Drugs & Drug Targets