Proto-Oncogene Proteins c-sis
- Name
- Proto-Oncogene Proteins c-sis
- Accession Number
- DBCAT004971
- Description
Cellular DNA-binding proteins encoded by the sis gene (GENES, SIS). c-sis proteins make up the B chain of PLATELET-DERIVED GROWTH FACTOR. Overexpression of c-sis causes tumorigenesis.
- Drugs
Drug Drug Description Becaplermin A recombinant form of human platelet-derived growth factor used to treat ulcers due to diabetic neuropathy in the lower extremities when there is adequate blood supply to the area. - Drugs & Drug Targets
Drug Target Type Becaplermin Platelet-derived growth factor receptor beta target Becaplermin Alpha-2-macroglobulin target Becaplermin Platelet-derived growth factor receptor alpha target