Direct Vasodilators

Name
Direct Vasodilators
Accession Number
DBCAT003665
Description

Not Available

Drugs
DrugDrug Description
NitroprussideA direct acting vasodilator used to treat hypertension, to induce controlled hypotension to reduce postoperative bleeding, and to manage acute heart failure.
MinoxidilAn antihypertensive vasodilating agent used for resistant hypertension that is symptomatic or has caused end organ damage.
DiazoxideA non diuretic benzothiadiazine indicated for the management of hypoglycemia in patients who produce an excess of insulin caused by a variety of conditions.
HydralazineAn antihypertensive agent used for the management of essential hypertension or severe hypertension associated with conditions requiring immediate action, heart failure, and pre-eclampsia or eclampsia .
Drugs & Drug Targets
DrugTargetType
NitroprussideAtrial natriuretic peptide receptor 1target
NitroprussideCytochrome P450 1A1enzyme
MinoxidilATP-sensitive inward rectifier potassium channel 1target
MinoxidilProstaglandin G/H synthase 1target
MinoxidilRenintarget
MinoxidilUDP-glucuronosyltransferase 1-1enzyme
DiazoxideATP-sensitive inward rectifier potassium channel 11target
DiazoxideSerum albumincarrier
DiazoxideMitochondrial ATP synthase F1 domaintarget
HydralazineMembrane primary amine oxidasetarget
HydralazineProlyl 4-hydroxylase subunit alpha-1target
HydralazineCytochrome P450 3A4enzyme
HydralazineSerum albumincarrier
HydralazineHypoxia-inducible factor 1-alphatarget