Epithelial Sodium Channel Blockers

Name

Epithelial Sodium Channel Blockers

Accession Number

DBCAT000817

Description

A subclass of sodium channel blockers that are specific for EPITHELIAL SODIUM CHANNELS.

Drugs

Drug	Drug Description
Triamterene	A potassium-sparing diuretic used in the treatment of edema and in the management of hypertension.
Amiloride	A pyrizine compound used to treat hypertension and congestive heart failure.

Drugs & Drug Targets

Drug	Target	Type
Triamterene	Amiloride-sensitive sodium channel subunit gamma	target
Triamterene	Amiloride-sensitive sodium channel subunit alpha	target
Triamterene	Amiloride-sensitive sodium channel subunit beta	target
Triamterene	Amiloride-sensitive sodium channel subunit delta	target
Triamterene	Cytochrome P450 1A2	enzyme
Amiloride	Amiloride-sensitive sodium channel subunit beta	target
Amiloride	Acid-sensing ion channel 1	target
Amiloride	Amiloride-sensitive amine oxidase [copper-containing]	target
Amiloride	Amiloride-sensitive sodium channel subunit alpha	target
Amiloride	Amiloride-sensitive sodium channel subunit gamma	target
Amiloride	Sodium/hydrogen exchanger 1	target
Amiloride	Acid-sensing ion channel 2	target
Amiloride	Amiloride-sensitive sodium channel subunit delta	target
Amiloride	Urokinase-type plasminogen activator	target
Amiloride	Solute carrier family 22 member 2	transporter
Amiloride	Solute carrier family 22 member 4	transporter
Amiloride	Amiloride-sensitive amine oxidase [copper-containing]	enzyme
Amiloride	Amiloride-sensitive amine oxidase [copper-containing]	enzyme