Glycoside Hydrolases
- Name
- Glycoside Hydrolases
- Accession Number
- DBCAT000166
- Description
Biological catalysts and their cofactors.
- Drugs
Drug Drug Description Hyaluronidase (ovine) A purified form of sheep hyaluronidase enzyme used as an adjunct in subcutaneous rehydration therapy and to increase absorption of other drugs and radiopaque imaging agents. Imiglucerase A form of recombinant human beta-glucocerebrosidase enzyme used to replace the deficient endogenous enzyme in the treatment of Gaucher disease. Alglucerase A form of recombinant beta-glucocerebrosidase enzyme used to replace the deficient endogenous enzyme in the treatment of Gaucher disease. Agalsidase beta A recombinant human alpha-galactosidase indicated to treat Fabry disease, a genetic deficiency in the enzyme leading to buildup of globotriaosylceramide. Alglucosidase alfa An acid alpha- glucosidase (GAA) derivative used as an enzyme replacement therapy for the treatment of Pompe disease in infants and pediatric patients caused by GAA deficiency. ALTU-135 Investigated for use/treatment in cystic fibrosis and pancreatic disorders. Sacrosidase An enzyme replacement therapy used for the treatment of congenital sucrase-isomaltase deficiency (CSID). Taliglucerase alfa A hydrolytic lysosomal glucocerebroside specific enzyme, used for long term enzyme replacement therapy in patients with Type 1 Gaucher disease. Pancrelipase amylase A lipase used to treat pancreatic exocrine insufficiency. Aviscumine Cy 503 is under investigation in clinical trial NCT00658437 (Aviscumine for the Treatment of Malignant Melanoma Stage IV After Failure of Prior Therapy). Lysozyme An enzyme indicated in the treatment of gastrointestinal disorders in infants, as well as Herpes zoster and Herpes simplex. Tilactase A beta-D-galactosidase use to treat lactose intolerance. Hyaluronidase (human recombinant) An enzyme used to improve the absorption and dispersion of parenterally administered fluids, drugs, and contrast agents. Hyaluronidase An enzyme used to improve the absorption and dispersion of parenterally administered fluids, drugs, and contrast agents. Valanafusp alfa Valanafusp alfa is under investigation in clinical trial NCT03071341 (Extension Study Evaluating Long Term Safety and Activity of AGT-181 in Children With MPS I). Agalsidase alfa A recombinant human alpha-galactosidase indicated to treat Fabry disease, a genetic deficiency in the enzyme leading to buildup of globotriaosylceramide. Laronidase A form of recombinant human alpha-L-iduronidase used to treat Hurler and Hurler-Scheie forms of mucopolysaccharidosis, a genetic deficiency of alpha-L-iduronidase. Vestronidase alfa A recombinant beta-glucuronidase used to treat mucopolysaccharidosis VII. Pegvorhyaluronidase alfa Pegvorhyaluronidase alfa is under investigation in clinical trial NCT02241187 (Two Stage Study Of Single Dose PEGPH20 And Cetuximab In Patients With Pancreatic Adenocarcinoma Prior To Surgical Resection). Tralesinidase alfa Tralesinidase alfa is a chimeric fusion protein comprised of recombinant human NAGLU and a modified human insulin-like growth factor 2. It is being investigated for the treatment of mucopolysaccharidosis type... XMMME-001-RTA Not Annotated XomaZyme-791 Not Annotated Liprotamase lipase Not Annotated - Drugs & Drug Targets