Histamine H1 Inhibitors

Accession Number

DBCAT003399

Description

Not Available

Drugs

Drug	Drug Description
Epinastine	An H1 receptor antagonist used to prevent itching in allergic conjunctivitis.
Olopatadine	A histamine H1 antagonist used to treat allergic conjunctivitis and rhinitis.
Ketotifen	A histamine H1 receptor blocker and mast cell stabilizer used to treat mild atopic asthma and allergic conjunctivitis.
Emedastine	A selective H1-receptor antagonist used topically to manage symptoms of allergic conjunctivitis.

Drugs & Drug Targets

Drug	Target	Type
Epinastine	Histamine H1 receptor	target
Epinastine	Histamine H2 receptor	target
Epinastine	Alpha-1A adrenergic receptor	target
Epinastine	Alpha-2A adrenergic receptor	target
Epinastine	5-hydroxytryptamine receptor 2A	target
Epinastine	5-hydroxytryptamine receptor 7	target
Epinastine	P-glycoprotein 1	transporter
Epinastine	Cytochrome P450 2B6	enzyme
Epinastine	Cytochrome P450 2D6	enzyme
Epinastine	Cytochrome P450 3A4	enzyme
Olopatadine	Histamine H1 receptor	target
Olopatadine	Protein S100-A1	target
Olopatadine	Protein S100-A12	target
Olopatadine	Protein S100-B	target
Olopatadine	Protein S100-A13	target
Olopatadine	Protein S100-A2	target
Olopatadine	Cytochrome P450 3A4	enzyme
Olopatadine	Serum albumin	carrier
Olopatadine	Dimethylaniline monooxygenase [N-oxide-forming] 1	enzyme
Olopatadine	Dimethylaniline monooxygenase [N-oxide-forming] 3	enzyme
Olopatadine	P-glycoprotein 1	transporter
Olopatadine	Histamine H2 receptor	target
Olopatadine	Histamine H3 receptor	target
Ketotifen	Histamine H1 receptor	target
Ketotifen	6-phosphogluconate dehydrogenase, decarboxylating	target
Ketotifen	UDP-glucuronosyltransferase 1-3	enzyme
Ketotifen	UDP-glucuronosyltransferase 1-4	enzyme
Ketotifen	UDP-glucuronosyltransferase 2B10	enzyme
Emedastine	Histamine H1 receptor	target