HIV Fusion Inhibitors
- Name
- HIV Fusion Inhibitors
- Accession Number
- DBCAT000220
- Description
Inhibitors of the fusion of HIV to host cells, preventing viral entry. This includes compounds that block attachment of HIV ENVELOPE PROTEIN GP120 to CD4 RECEPTORS.
- Drugs
Drug Drug Description Enfuvirtide An HIV-1 gp41 fusion inhibitor used in patients experiencing HIV-1 replication who are already being treated with other anti-retrovirals. Maraviroc A CCR5 co-receptor antagonist used with other antiretroviral medications to treat CCR5-tropic HIV-1 infection. BMS-488043 Investigated for use/treatment in HIV infection. PRO-542 Investigated for use/treatment in acquired immune deficiency syndrome (AIDS) and aids-related infections, HIV infection, and pediatric indications. Leronlimab A humanized monoclonal antibody being investigated Aplaviroc Investigated for use/treatment in HIV infection. Ibalizumab A CD4-specific antibody used to treat HIV infections. Temsavir Not Annotated Fostemsavir An antiretroviral HIV-1 attachment inhibitor targeted against the gp120 subunit within the HIV-1 gp160 envelope glycoprotein. - Drugs & Drug Targets