IMP Dehydrogenase, antagonists & inhibitors

Accession Number

DBCAT001071

Description

Not Available

Drugs

Drug	Drug Description
Mycophenolate mofetil	An inosine monophosphate dehydrogenase inhibitor used to prevent the rejection of kidney, heart, or liver transplants.
Merimepodib	For the treatment of hepatitis C virus (HCV) infection.
AVN-944	Investigated for use/treatment in cancer/tumors (unspecified), leukemia (unspecified), lymphoma (unspecified), multiple myeloma, and pancreatic cancer.
Mizoribine	Mizoribine has been investigated for the treatment of Rheumatoid Arthritis.

Drugs & Drug Targets

Drug	Target	Type
Mycophenolate mofetil	Inosine-5'-monophosphate dehydrogenase 2	target
Mycophenolate mofetil	Inosine-5'-monophosphate dehydrogenase 1	target
Mycophenolate mofetil	UDP-glucuronosyltransferase 1-1	enzyme
Mycophenolate mofetil	UDP-glucuronosyltransferase 1-7	enzyme
Mycophenolate mofetil	UDP-glucuronosyltransferase 1-6	enzyme
Mycophenolate mofetil	UDP-glucuronosyltransferase 1-9	enzyme
Mycophenolate mofetil	UDP-glucuronosyltransferase 2B7	enzyme
Mycophenolate mofetil	UDP-glucuronosyltransferase 1-8	enzyme
Mycophenolate mofetil	UDP-glucuronosyltransferase 1-10	enzyme
Mycophenolate mofetil	Liver carboxylesterase 1	enzyme
Mycophenolate mofetil	Cytochrome P450 3A4	enzyme
Mycophenolate mofetil	Cytochrome P450 3A5	enzyme
Mycophenolate mofetil	Cytochrome P450 2C8	enzyme
Mycophenolate mofetil	Solute carrier organic anion transporter family member 1B1	transporter
Mycophenolate mofetil	Solute carrier organic anion transporter family member 1B3	transporter
Mycophenolate mofetil	ATP-binding cassette sub-family G member 2	transporter
Mycophenolate mofetil	P-glycoprotein 1	transporter
Mycophenolate mofetil	6-pyruvoyl tetrahydrobiopterin synthase	target
Mycophenolate mofetil	Carboxylic ester hydrolase	enzyme
Mycophenolate mofetil	Canalicular multispecific organic anion transporter 1	transporter
Merimepodib	Inosine-5'-monophosphate dehydrogenase	target