Intercalating Agents
- Name
- Intercalating Agents
- Accession Number
- DBCAT000657
- Description
Agents that are capable of inserting themselves between the successive bases in DNA, thus kinking, uncoiling or otherwise deforming it and therefore preventing its proper functioning. They are used in the study of DNA.
- Drugs
Drug Drug Description Amsacrine A cytotoxic agent used to induce remission in acute adult leukemia that is not adequately responsive to other agents. Propidium Quaternary ammonium analog of ethidium; an intercalating dye with a specific affinity to certain forms of DNA and, used as diiodide, to separate them in density gradients; also forms fluorescent... 1,10-Phenanthroline Not Available Amonafide Investigated for use/treatment in breast cancer, ovarian cancer, and prostate cancer. Pyrazoloacridine Pyrazoloacridine has been used in trials studying the treatment of Lung Cancer, Liver Cancer, Breast Cancer, Melanoma (Skin), and Metastatic Cancer, among others. Acriflavine A topical antiseptic indicated in the treatment of infected wounds and for skin disinfection. - Drugs & Drug Targets