Mineralocorticoid Receptor Antagonists
- Name
- Mineralocorticoid Receptor Antagonists
- Accession Number
- DBCAT000844
- Description
Drugs that bind to and block the activation of MINERALOCORTICOID RECEPTORS by MINERALOCORTICOIDS such as ALDOSTERONE.
- ATC Classification
- Drugs
Drug Drug Description Spironolactone An aldosterone receptor antagonist used to treat edema, hypertension, heart failure, and aldosteronism. Eplerenone An aldosterone receptor antagonist used to improve survival of patients with symptomatic heart failure and to reduce blood pressure. Canrenoic acid An aldosterone antagonist used in primary hyperaldosteronism and other disorders related to aberrant aldosterone levels. Canrenone An antimineralocorticoid and active metabolite of spironolactone used in the treatment of primary hyperaldosteronism and edematous states caused by secondary hyperaldosteronism (e.g. heart failure). Drospirenone A progestin used in oral contraceptive pills for the prevention of pregnancy and other conditions. Finerenone A nonsteroidal mineralocorticoid receptor antagonist indicated to lower the risk of eGFR decline, end stage kidney disease, cardiovascular death, heart attack, and hospitalization for heart failure in chronic kidney disease associated with type 2 diabetes. - Drugs & Drug Targets