Norpregnatrienes

Name
Norpregnatrienes
Accession Number
DBCAT001216
Description

Pregnatrienes which have undergone ring contractions or are lacking carbon-18 or carbon-19.

Drugs
DrugDrug Description
EthinylestradiolAn estradiol used as a contraceptive.
NorgestrienoneNot Annotated
IfidancitinibIfidancitinib is under investigation in clinical trial NCT03585296 (A Study of ATI-502 Topical Solution for the Treatment of Atopic Dermatitis).
MestranolA synthetic estradiol found in oral contraceptive pills for contraception and the treatment of other conditions in the female reproductive system, such as dysmenorrhea and dysfunctional uterine bleeding.
QuinestrolUsed in hormone replacement therapy, treating symptoms of menopause such as hot flashes. Also used to treat breast and prostate cancer.
TetrahydrogestrinoneNot Available
GestrinoneEndometriosis with or without accompanying sterility. Treatment is limited to a single course of 6 months duration per lifetime [L1699, L1700].
MoxestrolNot Annotated
Segesterone acetateSegesterone acetate in combination with ethinyl estradiol is indicated for use by females of reproductive potential to prevent pregnancy as a combination hormonal contraceptive (CHC). It induces contraception for thirteen...
Drugs & Drug Targets
DrugTargetType
EthinylestradiolEstrogen receptor alphatarget
EthinylestradiolNuclear receptor subfamily 1 group I member 2target
EthinylestradiolCytochrome P450 3A4enzyme
EthinylestradiolCytochrome P450 2C8enzyme
EthinylestradiolBile salt export pumptransporter
EthinylestradiolSodium/bile acid cotransportertransporter
EthinylestradiolCanalicular multispecific organic anion transporter 1transporter
EthinylestradiolP-glycoprotein 1transporter
EthinylestradiolUDP-glucuronosyltransferase 1-1enzyme
EthinylestradiolCytochrome P450 2C19enzyme
EthinylestradiolUDP-glucuronosyltransferase 1-4enzyme
EthinylestradiolUDP-glucuronosyltransferase 1-9enzyme
EthinylestradiolCytochrome P450 2C9enzyme
EthinylestradiolCytochrome P450 1A2enzyme
EthinylestradiolEstrogen sulfotransferaseenzyme
EthinylestradiolSulfotransferase 1A3/1A4enzyme
EthinylestradiolCytochrome P450 3A5enzyme
EthinylestradiolUDP-glucuronosyltransferase 2B7enzyme
EthinylestradiolUDP-glucuronosyltransferase 1-3enzyme
EthinylestradiolCatechol O-methyltransferaseenzyme
EthinylestradiolSolute carrier organic anion transporter family member 1A2transporter
EthinylestradiolSerum albumincarrier
EthinylestradiolSex hormone-binding globulincarrier
MestranolEstrogen receptor alphatarget
MestranolCytochrome P450 2C9enzyme
MestranolCytochrome P450 3A4enzyme
MestranolCytochrome P450 2C8enzyme
QuinestrolEstrogen receptor alphatarget
TetrahydrogestrinoneAndrogen receptortarget
GestrinoneSex hormone-binding globulintarget
GestrinoneProgesterone receptortarget
GestrinoneGlucocorticoid receptortarget
GestrinoneAndrogen receptortarget
GestrinoneGonadotropin-releasing hormone receptortarget
GestrinoneEstrogen receptor alphatarget
GestrinoneCytochrome P450 3A4enzyme
Segesterone acetateGlucocorticoid receptortarget
Segesterone acetateProgesterone receptortarget
Segesterone acetateAndrogen receptortarget
Segesterone acetateCytochrome P450 3A4enzyme