Pituitary Hormones, Anterior

Name
Pituitary Hormones, Anterior
Accession Number
DBCAT000095
Description

Hormones secreted by the adenohypophysis (PITUITARY GLAND, ANTERIOR). Structurally, they include polypeptide, protein, and glycoprotein molecules.

Drugs
DrugDrug Description
TetracosactideA diagnostic agent used in the screening of patients presumed to have adrenocortical insufficiency.
CorticotropinA diagnostic agent used in the screening of patients presumed to have adrenocortical insufficiency.
SomatotropinA recombinant human growth hormone used as replacement therapy in various conditions of growth failure, growth hormone deficiency, and weakness in children and adults.
BremelanotideBremelanotide is indicated to treat premenopausal women with hypoactive sexual desire disorder that is not due to a medical or psychiatric condition, problems with the relationship, or the effects of...
SetmelanotideSetmelanotide is indicated to treat obesity caused by genetic POMC, PCSK1, or LEPR deficiencies or Bardet-Biedl syndrome.
SomapacitanA human growth hormone analog subcutaneous injection indicated for adults with growth hormone deficiency.
ThyrotropinA medication indicated in thyroid stimulation before radioactive iodine ablation or for thyroid imaging.
Thyrotropin alfaA recombinant form of thyroid stimulating hormone used in diagnostic testing for thyroid cancer and alongside radioactive agents to destroy thyroid tissue.
MenotropinsA purified combination of human luteinizing hormone and follicle stimulating hormone used to treat female infertility.
FollitropinA form of recombinant human follicle stimulating hormone used to stimulate follicle development in women with primary ovarian hypogonadism and in men with hypogonadotropic hypogonadism.
PegvisomantA growth hormone receptor antagonist used to treat acromegaly.
UrofollitropinA form of purified human follicle stimulating hormone used to treat infertility in females by inducing follicle development in women without primary ovarian failure.
Corifollitropin alfaA FSH analogue indicated for Controlled Ovarian Stimulation (COS) in combination with a GnRH antagonist for the development of multiple follicles in women participating in an Assisted Reproductive Technology (ART) program.
SomatremA recombinant growth hormone used to treat adult growth hormone deficiency and treat disrupted growth in children due to growth hormone insufficiency or deficiency, turner's syndrome, chronic renal failure, and small stature for gestational age.
Chorionic Gonadotropin (Human)A naturally-occurring hormone produced during human placenta used for the treatment of prepubertal cryptorchidism and hypogonadotropic hypogonadism in selected males, and induction of pregnancy in selected infertile women.
AlbusomatropinAlbusomatropin has been used in trials studying the treatment of Growth Hormone-Deficiency and Growth Hormone Deficiency.
AlsactideNot Annotated
Luteinizing hormoneNot Annotated
SomatrogonA long-acting recombinant human growth hormone used as the long-term treatment of pediatric patients who have growth failure due to growth hormone deficiency.
Somatropin pegolSomatropin pegol is under investigation in clinical trial NCT00715689 (Dose Study in Growth Hormone Deficient Adults Investigating Safety, Pharmacokinetics and Pharmacodynamics of NNC126-0083).
LonapegsomatropinA human growth hormone indicated in the treatment of growth failure due to inadequate endogenous growth hormone secretion.
IntermedineNot Annotated
Eftansomatropin alfaEftansomatropin alfa (GX-H9) comprises a recombinant human growth hormone fused to hyFc, a synthetic hybrid Fc fragment. It is under investigation for the treatment of growth hormone deficiency.
Drugs & Drug Targets
DrugTargetType
TetracosactideAdrenocorticotropic hormone receptortarget
CorticotropinAdrenocorticotropic hormone receptortarget
CorticotropinCorticoliberintarget
Corticotropin3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 2enzyme
Corticotropin25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrialenzyme
Corticotropin1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrialenzyme
CorticotropinCytochrome P450 3A4enzyme
SomatotropinGrowth hormone receptortarget
SomatotropinProlactin receptortarget
SomatotropinCytochrome P450 1A2enzyme
SomatotropinCytochrome P450 2C19enzyme
SomatotropinP-glycoprotein 1transporter
BremelanotideMelanocyte-stimulating hormone receptortarget
BremelanotideMelanocortin receptor 4target
BremelanotideMelanocortin receptor 3target
BremelanotideMelanocortin receptor 5target
BremelanotideAdrenocorticotropic hormone receptortarget
SetmelanotideMelanocortin receptor 4target
SomapacitanCorticosteroid 11-beta-dehydrogenase isozyme 1enzyme
SomapacitanCytochrome P450 2C12, female-specificenzyme
SomapacitanCytochrome P450 1A2enzyme
SomapacitanCytochrome P450 2C19enzyme
SomapacitanSerum albumincarrier
SomapacitanGrowth hormone receptortarget
Thyrotropin alfaThyrotropin receptortarget
MenotropinsFollicle-stimulating hormone receptortarget
MenotropinsLutropin-choriogonadotropic hormone receptortarget
FollitropinFollicle-stimulating hormone receptortarget
PegvisomantGrowth hormone receptortarget
PegvisomantSterol 26-hydroxylase, mitochondrialenzyme
PegvisomantGlutamine synthetaseenzyme
PegvisomantCytochrome P450 3A4enzyme
PegvisomantCholinesteraseenzyme
PegvisomantCytochrome P450 4A11enzyme
UrofollitropinFollicle-stimulating hormone receptortarget
Corifollitropin alfaFollicle-stimulating hormone receptortarget
SomatremGrowth hormone receptortarget
SomatremInsulin-like growth factor 1 receptortarget
Chorionic Gonadotropin (Human)Lutropin-choriogonadotropic hormone receptortarget
SomatrogonGrowth hormone receptortarget
LonapegsomatropinCorticosteroid 11-beta-dehydrogenase isozyme 1enzyme
LonapegsomatropinGrowth hormone receptortarget
LonapegsomatropinProlactin receptortarget
LonapegsomatropinCytochrome P450 1A2enzyme
LonapegsomatropinCytochrome P450 2C19enzyme
LonapegsomatropinP-glycoprotein 1transporter