Receptors, Thrombopoietin, agonists
- Name
- Receptors, Thrombopoietin, agonists
- Accession Number
- DBCAT001695
- Description
Not Available
- Drugs
Drug Drug Description Romiplostim A fusion protein thrombopoietin (TPO) peptide analog that increases platelet counts by binding to and activating the human TPO receptor. Used to treat thrombocytopenia associated with chronic immune thrombocytopenia (ITP). Avatrombopag A thrombopoietin receptor agonist used pre-operatively to treat thrombocytopenia in patients with chronic liver disease and in patients with chronic refractory thrombocytopenia. - Drugs & Drug Targets
Drug Target Type Romiplostim Thrombopoietin receptor target Avatrombopag Cytochrome P450 2C8 enzyme Avatrombopag Cytochrome P450 2C9 enzyme Avatrombopag Thrombopoietin receptor target Avatrombopag P-glycoprotein 1 transporter Avatrombopag Cytochrome P450 3A4 enzyme Avatrombopag ATP-binding cassette sub-family G member 2 transporter Avatrombopag Solute carrier family 22 member 8 transporter